ES2711881T3 - Detección y cuantificación de ácidos nucleicos para valorar la biomasa microbiana en los defectos del papel y en los fieltros de máquina - Google Patents
Detección y cuantificación de ácidos nucleicos para valorar la biomasa microbiana en los defectos del papel y en los fieltros de máquina Download PDFInfo
- Publication number
- ES2711881T3 ES2711881T3 ES13741346T ES13741346T ES2711881T3 ES 2711881 T3 ES2711881 T3 ES 2711881T3 ES 13741346 T ES13741346 T ES 13741346T ES 13741346 T ES13741346 T ES 13741346T ES 2711881 T3 ES2711881 T3 ES 2711881T3
- Authority
- ES
- Spain
- Prior art keywords
- organisms
- article
- defect
- pcr analysis
- organism
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 230000007547 defect Effects 0.000 title claims abstract description 62
- 230000000813 microbial effect Effects 0.000 title description 24
- 238000001514 detection method Methods 0.000 title description 11
- 108020004707 nucleic acids Proteins 0.000 title description 6
- 102000039446 nucleic acids Human genes 0.000 title description 6
- 150000007523 nucleic acids Chemical class 0.000 title description 6
- 239000002028 Biomass Substances 0.000 title description 2
- 238000011002 quantification Methods 0.000 title description 2
- 238000000034 method Methods 0.000 claims abstract description 107
- 244000005700 microbiome Species 0.000 claims abstract description 69
- 238000004458 analytical method Methods 0.000 claims abstract description 26
- 238000010222 PCR analysis Methods 0.000 claims abstract description 23
- 230000008569 process Effects 0.000 claims abstract description 20
- 208000015181 infectious disease Diseases 0.000 claims abstract description 9
- 108091028043 Nucleic acid sequence Proteins 0.000 claims abstract description 4
- 238000005259 measurement Methods 0.000 claims abstract description 4
- 241000894006 Bacteria Species 0.000 claims description 25
- 238000011529 RT qPCR Methods 0.000 claims description 18
- 230000003044 adaptive effect Effects 0.000 claims description 12
- 238000001035 drying Methods 0.000 claims description 6
- 230000003115 biocidal effect Effects 0.000 claims description 3
- 238000010438 heat treatment Methods 0.000 claims description 2
- 238000005067 remediation Methods 0.000 claims description 2
- 239000000123 paper Substances 0.000 description 66
- 108020004414 DNA Proteins 0.000 description 28
- 238000009740 moulding (composite fabrication) Methods 0.000 description 20
- 239000000523 sample Substances 0.000 description 20
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 19
- 230000001580 bacterial effect Effects 0.000 description 11
- 239000000126 substance Substances 0.000 description 11
- 230000015572 biosynthetic process Effects 0.000 description 10
- 238000003752 polymerase chain reaction Methods 0.000 description 10
- 210000004027 cell Anatomy 0.000 description 9
- 239000007788 liquid Substances 0.000 description 9
- 239000004744 fabric Substances 0.000 description 7
- 238000004519 manufacturing process Methods 0.000 description 7
- 239000000047 product Substances 0.000 description 7
- 238000011282 treatment Methods 0.000 description 6
- 238000006243 chemical reaction Methods 0.000 description 5
- 230000000694 effects Effects 0.000 description 5
- 239000000835 fiber Substances 0.000 description 5
- 239000000463 material Substances 0.000 description 5
- 239000000203 mixture Substances 0.000 description 5
- 238000012544 monitoring process Methods 0.000 description 5
- 238000011269 treatment regimen Methods 0.000 description 5
- 239000000654 additive Substances 0.000 description 4
- 238000011109 contamination Methods 0.000 description 4
- 230000003247 decreasing effect Effects 0.000 description 4
- 239000012467 final product Substances 0.000 description 4
- FEMOMIGRRWSMCU-UHFFFAOYSA-N ninhydrin Chemical compound C1=CC=C2C(=O)C(O)(O)C(=O)C2=C1 FEMOMIGRRWSMCU-UHFFFAOYSA-N 0.000 description 4
- 239000007800 oxidant agent Substances 0.000 description 4
- 238000007747 plating Methods 0.000 description 4
- 238000003825 pressing Methods 0.000 description 4
- 238000003753 real-time PCR Methods 0.000 description 4
- 230000009467 reduction Effects 0.000 description 4
- 229920002477 rna polymer Polymers 0.000 description 4
- 241000894007 species Species 0.000 description 4
- 108020004635 Complementary DNA Proteins 0.000 description 3
- 241000921347 Meiothermus Species 0.000 description 3
- 239000003139 biocide Substances 0.000 description 3
- 238000010804 cDNA synthesis Methods 0.000 description 3
- 230000008859 change Effects 0.000 description 3
- 239000002299 complementary DNA Substances 0.000 description 3
- 230000006872 improvement Effects 0.000 description 3
- 238000011065 in-situ storage Methods 0.000 description 3
- 239000002773 nucleotide Substances 0.000 description 3
- 125000003729 nucleotide group Chemical group 0.000 description 3
- 108090000623 proteins and genes Proteins 0.000 description 3
- 238000004445 quantitative analysis Methods 0.000 description 3
- 238000003786 synthesis reaction Methods 0.000 description 3
- 229920003043 Cellulose fiber Polymers 0.000 description 2
- 241000233866 Fungi Species 0.000 description 2
- 102100034343 Integrase Human genes 0.000 description 2
- 241001647875 Pseudoxanthomonas Species 0.000 description 2
- 108010092799 RNA-directed DNA polymerase Proteins 0.000 description 2
- 230000003321 amplification Effects 0.000 description 2
- 238000009835 boiling Methods 0.000 description 2
- 239000007795 chemical reaction product Substances 0.000 description 2
- 210000000038 chest Anatomy 0.000 description 2
- 230000000295 complement effect Effects 0.000 description 2
- 230000002950 deficient Effects 0.000 description 2
- 239000000284 extract Substances 0.000 description 2
- -1 newspaper Substances 0.000 description 2
- 238000003199 nucleic acid amplification method Methods 0.000 description 2
- 238000004451 qualitative analysis Methods 0.000 description 2
- 239000002994 raw material Substances 0.000 description 2
- 239000007787 solid Substances 0.000 description 2
- 238000010186 staining Methods 0.000 description 2
- 108091093088 Amplicon Proteins 0.000 description 1
- 239000004382 Amylase Substances 0.000 description 1
- 102000013142 Amylases Human genes 0.000 description 1
- 108010065511 Amylases Proteins 0.000 description 1
- 241001626813 Anoxybacillus Species 0.000 description 1
- 241000193830 Bacillus <bacterium> Species 0.000 description 1
- 208000035143 Bacterial infection Diseases 0.000 description 1
- 241001453380 Burkholderia Species 0.000 description 1
- 102100035882 Catalase Human genes 0.000 description 1
- 108010053835 Catalase Proteins 0.000 description 1
- ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 description 1
- 238000007400 DNA extraction Methods 0.000 description 1
- 238000013382 DNA quantification Methods 0.000 description 1
- 108010014303 DNA-directed DNA polymerase Proteins 0.000 description 1
- 102000016928 DNA-directed DNA polymerase Human genes 0.000 description 1
- 241000192093 Deinococcus Species 0.000 description 1
- 241000192095 Deinococcus-Thermus Species 0.000 description 1
- 102000004190 Enzymes Human genes 0.000 description 1
- 108090000790 Enzymes Proteins 0.000 description 1
- 206010017533 Fungal infection Diseases 0.000 description 1
- 241000204444 Haliscomenobacter Species 0.000 description 1
- 241000863029 Herpetosiphon Species 0.000 description 1
- 241000862991 Leptothrix <Bacteria> Species 0.000 description 1
- 208000031888 Mycoses Diseases 0.000 description 1
- 239000004677 Nylon Substances 0.000 description 1
- 241000589516 Pseudomonas Species 0.000 description 1
- 241000191112 Saprospira Species 0.000 description 1
- 241001597509 Schlegelella Species 0.000 description 1
- 241001478896 Sphaerotilus natans Species 0.000 description 1
- 241000131972 Sphingomonadaceae Species 0.000 description 1
- 241000736131 Sphingomonas Species 0.000 description 1
- 229920002472 Starch Polymers 0.000 description 1
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 description 1
- 108010046334 Urease Proteins 0.000 description 1
- 229920002522 Wood fibre Polymers 0.000 description 1
- 230000002411 adverse Effects 0.000 description 1
- 235000019418 amylase Nutrition 0.000 description 1
- 208000022362 bacterial infectious disease Diseases 0.000 description 1
- 230000004071 biological effect Effects 0.000 description 1
- 238000004061 bleaching Methods 0.000 description 1
- 238000004364 calculation method Methods 0.000 description 1
- 238000003490 calendering Methods 0.000 description 1
- 239000003518 caustics Substances 0.000 description 1
- 230000001413 cellular effect Effects 0.000 description 1
- 239000002894 chemical waste Substances 0.000 description 1
- 239000000460 chlorine Substances 0.000 description 1
- 229910052801 chlorine Inorganic materials 0.000 description 1
- 238000004140 cleaning Methods 0.000 description 1
- 230000001332 colony forming effect Effects 0.000 description 1
- 239000003086 colorant Substances 0.000 description 1
- 230000002860 competitive effect Effects 0.000 description 1
- 108091036078 conserved sequence Proteins 0.000 description 1
- 239000000356 contaminant Substances 0.000 description 1
- 238000003745 diagnosis Methods 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 230000029087 digestion Effects 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 230000002255 enzymatic effect Effects 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 230000001815 facial effect Effects 0.000 description 1
- 230000002349 favourable effect Effects 0.000 description 1
- 239000012634 fragment Substances 0.000 description 1
- 239000013505 freshwater Substances 0.000 description 1
- 230000002538 fungal effect Effects 0.000 description 1
- 239000001963 growth medium Substances 0.000 description 1
- 125000001475 halogen functional group Chemical group 0.000 description 1
- 238000000338 in vitro Methods 0.000 description 1
- 239000008235 industrial water Substances 0.000 description 1
- 230000007257 malfunction Effects 0.000 description 1
- 239000012528 membrane Substances 0.000 description 1
- 108020004999 messenger RNA Proteins 0.000 description 1
- 230000002906 microbiologic effect Effects 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 235000015097 nutrients Nutrition 0.000 description 1
- 229920001778 nylon Polymers 0.000 description 1
- 230000008520 organization Effects 0.000 description 1
- 230000001590 oxidative effect Effects 0.000 description 1
- 230000002085 persistent effect Effects 0.000 description 1
- 150000003141 primary amines Chemical class 0.000 description 1
- 238000007639 printing Methods 0.000 description 1
- 230000035755 proliferation Effects 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 238000004537 pulping Methods 0.000 description 1
- 239000011541 reaction mixture Substances 0.000 description 1
- 230000002829 reductive effect Effects 0.000 description 1
- 238000007670 refining Methods 0.000 description 1
- 230000033764 rhythmic process Effects 0.000 description 1
- 210000003705 ribosome Anatomy 0.000 description 1
- 150000003335 secondary amines Chemical class 0.000 description 1
- 239000010802 sludge Substances 0.000 description 1
- 238000004611 spectroscopical analysis Methods 0.000 description 1
- 239000007921 spray Substances 0.000 description 1
- 239000008107 starch Substances 0.000 description 1
- 235000019698 starch Nutrition 0.000 description 1
- 238000003860 storage Methods 0.000 description 1
- 239000000758 substrate Substances 0.000 description 1
- 239000011593 sulfur Substances 0.000 description 1
- 229910052717 sulfur Inorganic materials 0.000 description 1
- 239000000725 suspension Substances 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
- 210000001519 tissue Anatomy 0.000 description 1
- 238000013519 translation Methods 0.000 description 1
- 230000035899 viability Effects 0.000 description 1
- 238000003809 water extraction Methods 0.000 description 1
- 239000002025 wood fiber Substances 0.000 description 1
- 210000002268 wool Anatomy 0.000 description 1
Classifications
-
- D—TEXTILES; PAPER
- D21—PAPER-MAKING; PRODUCTION OF CELLULOSE
- D21H—PULP COMPOSITIONS; PREPARATION THEREOF NOT COVERED BY SUBCLASSES D21C OR D21D; IMPREGNATING OR COATING OF PAPER; TREATMENT OF FINISHED PAPER NOT COVERED BY CLASS B31 OR SUBCLASS D21G; PAPER NOT OTHERWISE PROVIDED FOR
- D21H21/00—Non-fibrous material added to the pulp, characterised by its function, form or properties; Paper-impregnating or coating material, characterised by its function, form or properties
- D21H21/02—Agents for preventing deposition on the paper mill equipment, e.g. pitch or slime control
- D21H21/04—Slime-control agents
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
- C12Q1/689—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria
-
- D—TEXTILES; PAPER
- D21—PAPER-MAKING; PRODUCTION OF CELLULOSE
- D21H—PULP COMPOSITIONS; PREPARATION THEREOF NOT COVERED BY SUBCLASSES D21C OR D21D; IMPREGNATING OR COATING OF PAPER; TREATMENT OF FINISHED PAPER NOT COVERED BY CLASS B31 OR SUBCLASS D21G; PAPER NOT OTHERWISE PROVIDED FOR
- D21H17/00—Non-fibrous material added to the pulp, characterised by its constitution; Paper-impregnating material characterised by its constitution
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Analytical Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Paper (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US13/374,949 US8613837B2 (en) | 2012-01-24 | 2012-01-24 | Detection and quantification of nucleic acid to assess microbial biomass in paper defects and machine felts |
| PCT/US2013/022845 WO2013112656A1 (en) | 2012-01-24 | 2013-01-24 | Detection and quantification of nucleic acid to assess microbial biomass in paper defects and machine felts |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2711881T3 true ES2711881T3 (es) | 2019-05-08 |
Family
ID=48796278
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES13741346T Active ES2711881T3 (es) | 2012-01-24 | 2013-01-24 | Detección y cuantificación de ácidos nucleicos para valorar la biomasa microbiana en los defectos del papel y en los fieltros de máquina |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US8613837B2 (https=) |
| EP (1) | EP2807268B1 (https=) |
| JP (2) | JP6466715B2 (https=) |
| KR (1) | KR102037510B1 (https=) |
| CN (1) | CN104039976B (https=) |
| BR (1) | BR112014016391B1 (https=) |
| CA (1) | CA2858102C (https=) |
| ES (1) | ES2711881T3 (https=) |
| IN (1) | IN2014DN06136A (https=) |
| WO (1) | WO2013112656A1 (https=) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9295745B2 (en) | 2012-01-24 | 2016-03-29 | Nalco Company | Method for constructing a diversity index and a viability index of microorganisms in process samples |
| US9290802B2 (en) * | 2012-01-24 | 2016-03-22 | Nalco Company | Detection and quantification of nucleic acid to assess microbial biomass in paper defects and machine felts |
| TWI582238B (zh) | 2012-07-17 | 2017-05-11 | 奈寇公司 | 建構於處理樣品中微生物的多樣性指數及生存力指數之方法 |
| US9908796B2 (en) | 2012-10-23 | 2018-03-06 | Ecolab Usa Inc. | Use of oxidizing and non-oxidizing biocides for control of bacteria tolerant to stabilized-oxidant treatment |
| US9909219B2 (en) | 2014-04-14 | 2018-03-06 | Ecolab Usa Inc. | Slurry biocide |
| FI128362B (en) | 2015-02-27 | 2020-04-15 | Kemira Oyj | Procedure for Quantitative Monitoring of Endospores in the Aquatic Environment of a Paper or Cardboard Factory |
| US11608516B2 (en) * | 2015-04-15 | 2023-03-21 | Ecolab Usa Inc. | Method for determination of diversity and viability thresholds used to assess microorganisms in process samples |
| CN110868856A (zh) | 2017-07-12 | 2020-03-06 | 埃科莱布美国股份有限公司 | 在工业工艺中快速检测细菌孢子的方法 |
| CN110643504A (zh) * | 2019-11-08 | 2020-01-03 | 芬欧汇川(中国)有限公司 | 用于检测纸机系统浆样中蛋白质物质的设备及方法 |
| CN118922522A (zh) | 2022-01-20 | 2024-11-08 | 埃科莱布美国股份有限公司 | 从工业设备中移除微生物或生物膜的酶促清洁方法 |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3817828A (en) * | 1970-09-30 | 1974-06-18 | B Bendiner | Method of microbiological control of paper mill processes |
| US5190728A (en) | 1991-10-21 | 1993-03-02 | Nalco Chemical Company | Apparatus for monitoring fouling in commercial waters |
| JP3788999B2 (ja) | 1994-04-12 | 2006-06-21 | ソマール株式会社 | 抄紙斑点の原因となる微生物の検知方法及びそれに用いるプライマー |
| US5928875A (en) | 1998-05-27 | 1999-07-27 | Betzdearborn Inc. | Primers for the detection of spore forming bacteria |
| US20040014122A1 (en) * | 1998-05-27 | 2004-01-22 | Breen Alexander W. | Detection of spore forming bacteria |
| BRPI0206375B1 (pt) * | 2001-01-09 | 2015-08-04 | Kurita Water Ind Ltd | Método para seleção de agente antimicrobiano e utilização do mesmo |
| JP4207419B2 (ja) * | 2001-11-29 | 2009-01-14 | 栗田工業株式会社 | 製紙工程における製品の付着物の付着原因発生場所の探索方法および微生物制御方法 |
| JP2003164282A (ja) * | 2001-11-29 | 2003-06-10 | Rakan:Kk | 微生物の検出方法、及び微生物の検出用プライマーセット |
| US7306702B2 (en) | 2002-07-12 | 2007-12-11 | Hercules Incorporation | Enzymatic press felt treatment |
| WO2004042082A1 (en) | 2002-11-06 | 2004-05-21 | Kemira Oyj | A method for monitoring the presence of harmful microorganisms in paper industry |
| JP2005006557A (ja) * | 2003-06-19 | 2005-01-13 | Asahi Breweries Ltd | Ｐｃｒによるビール有害乳酸菌の同定法 |
| JP4788150B2 (ja) | 2005-02-10 | 2011-10-05 | 栗田工業株式会社 | 製紙工程における付着物の分析方法 |
| WO2006137183A1 (ja) * | 2005-06-22 | 2006-12-28 | Hsp Hanbai Kabushiki Kaisha | 製紙方法 |
| CA2524086A1 (en) | 2005-10-21 | 2007-04-21 | Canadian Blood Services | A method for detection of bacterial contamination in a blood sample |
| FI119903B (fi) * | 2006-03-16 | 2009-05-15 | Kemira Oyj | Bakteeri-itiöiden muodostumisen estäminen kartonkikoneen hylkysysteemissä |
| US7949432B2 (en) | 2007-02-16 | 2011-05-24 | Nalco Company | Method of monitoring surface associated microbiological activity in process streams |
| US8012758B2 (en) | 2007-02-16 | 2011-09-06 | Nalco Company | Method of monitoring microbiological activity in process streams |
| US7981679B2 (en) | 2007-02-16 | 2011-07-19 | Nalco Company | Method of monitoring bulk (total) microbiological activity in process streams |
| EP2480719A1 (en) * | 2009-09-22 | 2012-08-01 | SONOCO Development Inc. | Paperboard containing a biocide and method for making the same |
| JP5574221B2 (ja) * | 2010-02-22 | 2014-08-20 | 独立行政法人酒類総合研究所 | 醸造酒に含まれる微生物由来のｄｎａの検出方法 |
-
2012
- 2012-01-24 US US13/374,949 patent/US8613837B2/en active Active
-
2013
- 2013-01-24 EP EP13741346.4A patent/EP2807268B1/en active Active
- 2013-01-24 ES ES13741346T patent/ES2711881T3/es active Active
- 2013-01-24 KR KR1020147023565A patent/KR102037510B1/ko active Active
- 2013-01-24 CA CA2858102A patent/CA2858102C/en active Active
- 2013-01-24 JP JP2014553545A patent/JP6466715B2/ja active Active
- 2013-01-24 WO PCT/US2013/022845 patent/WO2013112656A1/en not_active Ceased
- 2013-01-24 IN IN6136DEN2014 patent/IN2014DN06136A/en unknown
- 2013-01-24 CN CN201380004704.XA patent/CN104039976B/zh active Active
- 2013-01-24 BR BR112014016391-0A patent/BR112014016391B1/pt active IP Right Grant
-
2017
- 2017-06-07 JP JP2017112557A patent/JP2017153488A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| JP6466715B2 (ja) | 2019-02-06 |
| US20130186582A1 (en) | 2013-07-25 |
| CN104039976B (zh) | 2017-02-22 |
| CA2858102A1 (en) | 2013-08-01 |
| WO2013112656A1 (en) | 2013-08-01 |
| US8613837B2 (en) | 2013-12-24 |
| JP2015505460A (ja) | 2015-02-23 |
| IN2014DN06136A (https=) | 2015-08-14 |
| CA2858102C (en) | 2021-04-06 |
| EP2807268A1 (en) | 2014-12-03 |
| BR112014016391A8 (pt) | 2017-07-04 |
| EP2807268A4 (en) | 2016-05-11 |
| JP2017153488A (ja) | 2017-09-07 |
| BR112014016391B1 (pt) | 2021-10-13 |
| BR112014016391A2 (pt) | 2017-06-13 |
| CN104039976A (zh) | 2014-09-10 |
| EP2807268B1 (en) | 2018-11-28 |
| KR20140131928A (ko) | 2014-11-14 |
| KR102037510B1 (ko) | 2019-10-28 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ES2711881T3 (es) | Detección y cuantificación de ácidos nucleicos para valorar la biomasa microbiana en los defectos del papel y en los fieltros de máquina | |
| CN104471072B (zh) | 构建工艺样品中微生物的多样性指数和生存力指数的方法 | |
| US9295745B2 (en) | Method for constructing a diversity index and a viability index of microorganisms in process samples | |
| AU2021289073A1 (en) | Methods of determining bacteria and manufacturing a fibrous web and tools and uses related thereto | |
| JP6892390B2 (ja) | プロセスサンプル中の微生物を評価するために使用される多様度及び生存度の閾値の決定のための方法 | |
| US9290802B2 (en) | Detection and quantification of nucleic acid to assess microbial biomass in paper defects and machine felts | |
| WO2015100123A1 (en) | Detection and quantification of nucleic acid to assess microbial biomass in paper defects and machine felts | |
| US20230220621A1 (en) | A method of controlling enzymatic activities and tools related thereto | |
| Haapala | i, United States Patent (10) Patent No.: US 8,613.837 B2 | |
| BR112017021943B1 (pt) | Método para antecipar um problema causado por microrganismo em um sistema de processo de água |