ES2687706T3 - Anticuerpos útiles en la inmunización pasiva contra la gripe - Google Patents
Anticuerpos útiles en la inmunización pasiva contra la gripe Download PDFInfo
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- ES2687706T3 ES2687706T3 ES11796555.8T ES11796555T ES2687706T3 ES 2687706 T3 ES2687706 T3 ES 2687706T3 ES 11796555 T ES11796555 T ES 11796555T ES 2687706 T3 ES2687706 T3 ES 2687706T3
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
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- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
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- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
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| US201161443103P | 2011-02-15 | 2011-02-15 | |
| US201161443103P | 2011-02-15 | ||
| US201161445455P | 2011-02-22 | 2011-02-22 | |
| US201161445455P | 2011-02-22 | ||
| PCT/US2011/040982 WO2011160083A1 (en) | 2010-06-17 | 2011-06-17 | Antibodies useful in passive influenza immuization |
Publications (1)
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| ES2687706T3 true ES2687706T3 (es) | 2018-10-26 |
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| EP (1) | EP2582721B1 (enExample) |
| JP (1) | JP6050747B2 (enExample) |
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| WO2013086052A2 (en) | 2011-12-05 | 2013-06-13 | Trellis Bioscience, Llc | Antibodies useful in passive influenza immunization |
| US9969794B2 (en) | 2012-05-10 | 2018-05-15 | Visterra, Inc. | HA binding agents |
| EA201892509A1 (ru) | 2012-11-13 | 2019-04-30 | Дженентек, Инк. | Антитела к гемагглютинину и способы применения |
| US11827693B2 (en) | 2013-03-14 | 2023-11-28 | Contrafect Corporation | Composition and methods based on neutralizing antibodies delivered intranasally for enhanced therapeutic efficacy |
| WO2015120097A2 (en) | 2014-02-04 | 2015-08-13 | Contrafect Corporation | Antibodies useful in passive influenza immunization, and compositions, combinations and methods for use thereof |
| US10639370B2 (en) * | 2014-02-04 | 2020-05-05 | Contrafect Corporation | Antibodies useful in passive influenza immunization, and compositions, combinations and methods for use thereof |
| WO2015140304A1 (en) * | 2014-03-20 | 2015-09-24 | Inflarx Gmbh | Inhibitors of c5a for the treatment of viral pneumonia |
| TWI702229B (zh) | 2014-12-19 | 2020-08-21 | 美商再生元醫藥公司 | 流行性感冒病毒血球凝集素之人類抗體 |
| EP3374390A1 (en) | 2015-11-13 | 2018-09-19 | Visterra, Inc. | Compositions and methods for treating and preventing influenza |
| JP7104629B2 (ja) | 2016-02-24 | 2022-07-21 | ビステラ， インコーポレイテッド | インフルエンザウイルスに対する抗体分子の製剤 |
| CN109476728A (zh) | 2016-07-14 | 2019-03-15 | 生命北极公司 | 脑部递送蛋白 |
| EP3731862A1 (en) * | 2017-12-29 | 2020-11-04 | Development Center for Biotechnology | A universal vaccine against influenza |
| CA3088194A1 (en) | 2018-01-26 | 2019-08-01 | Regeneron Pharmaceuticals, Inc. | Human antibodies to influenza hemagglutinin |
| AU2020248404A1 (en) | 2019-03-25 | 2021-09-30 | Visterra, Inc. | Compositions and methods for treating and preventing influenza |
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| US6235708B1 (en) | 1998-11-20 | 2001-05-22 | Zymogenetics, Inc | Testis-specific cystatin-like protein cystatin T |
| US20020006656A1 (en) | 1999-12-23 | 2002-01-17 | Holloway James L. | Zcys5: a member of the cystatin superfamily |
| US8420353B2 (en) | 2002-03-22 | 2013-04-16 | Aprogen, Inc. | Humanized antibody and process for preparing same |
| NZ542226A (en) | 2003-03-07 | 2008-08-29 | Merck & Co Inc | Influenza virus vaccine |
| KR101206206B1 (ko) | 2003-07-22 | 2012-11-29 | 크루셀 홀란드 비.브이. | 사스-코로나바이러스에 대한 결합분자 및 그것의 용도 |
| CN1934133B (zh) * | 2003-07-23 | 2011-12-14 | 富士瑞必欧株式会社 | 抗a型流感病毒单克隆抗体及使用该抗体的免疫测定器具 |
| US7413868B2 (en) | 2003-11-05 | 2008-08-19 | Trellis Bioscience, Inc. | Use of particulate labels in bioanalyte detection methods |
| US20080014205A1 (en) | 2006-05-15 | 2008-01-17 | Lawrence Horowitz | Neutralizing Antibodies to Influenza Viruses |
| US8192927B2 (en) | 2006-09-07 | 2012-06-05 | Crucell Holland B.V. | Human bind molecules capable of neutralizing influenza virus h5n1 and uses thereof |
| RU2448979C2 (ru) * | 2006-12-14 | 2012-04-27 | Ридженерон Фармасьютикалз, Инк. | Антитела человека к дельта-подобному лиганду-4 человека |
| EP3333187B1 (en) * | 2007-12-06 | 2022-06-22 | Dana-Farber Cancer Institute, Inc. | Antibodies against influenza virus and methods of use thereof |
| CA2719201A1 (en) * | 2008-03-28 | 2009-10-01 | Sea Lane Biotechnologies, Llc. | Neutralizing molecules to viral antigens |
| AU2009275226B2 (en) * | 2008-07-25 | 2015-05-14 | Institute For Research In Biomedicine | Neutralizing anti-influenza a virus antibodies and uses thereof |
| TW201019959A (en) | 2008-08-19 | 2010-06-01 | Regeneron Pharma | Human antibodies to human RANKL |
| CN102292350A (zh) | 2008-12-24 | 2011-12-21 | 淡马锡生命科学研究院有限公司 | 对来自甲型流感病毒血凝素的融合肽特异的单克隆抗体及其用途 |
| WO2011117848A1 (en) | 2010-03-26 | 2011-09-29 | Pomona Ricerca S.R.L. | Full-length immunoglobulins of the igg isotvpe capable of recognizing a heterosubtvpe neutralizing epitope on the hemagglutinin stem region and their use as anti-influenza medicament |
| EP2603237A4 (en) * | 2010-08-12 | 2014-05-21 | Theraclone Sciences Inc | ANTI-HEMAGGLUTININE ANTIBODY COMPOSITIONS AND METHOD FOR THEIR USE |
| WO2012045001A2 (en) * | 2010-09-30 | 2012-04-05 | Vanderbilt University | Influenza virus antibodies and immunogens and uses therefor |
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| BR112012032185A2 (pt) | 2016-10-11 |
| AU2011268072A1 (en) | 2013-01-31 |
| KR20130137584A (ko) | 2013-12-17 |
| AU2011268072B2 (en) | 2017-03-09 |
| US20120020971A1 (en) | 2012-01-26 |
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| EP2582721A1 (en) | 2013-04-24 |
| AU2017203924B2 (en) | 2019-08-08 |
| KR101849738B1 (ko) | 2018-04-17 |
| JP2013531993A (ja) | 2013-08-15 |
| CN106397584A (zh) | 2017-02-15 |
| AU2011268072C1 (en) | 2017-10-19 |
| RU2013102073A (ru) | 2014-07-27 |
| RU2635999C2 (ru) | 2017-11-17 |
| WO2011160083A1 (en) | 2011-12-22 |
| DK2582721T3 (en) | 2018-10-01 |
| EP2582721B1 (en) | 2018-08-22 |
| US10676520B2 (en) | 2020-06-09 |
| CA2839421C (en) | 2019-12-03 |
| AU2011268072A2 (en) | 2013-02-28 |
| JP6050747B2 (ja) | 2016-12-21 |
| EP2582721A4 (en) | 2013-11-20 |
| CA2839421A1 (en) | 2011-12-22 |
| CN103209994A (zh) | 2013-07-17 |
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