ES2687706T3 - Anticuerpos útiles en la inmunización pasiva contra la gripe - Google Patents
Anticuerpos útiles en la inmunización pasiva contra la gripe Download PDFInfo
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- ES2687706T3 ES2687706T3 ES11796555.8T ES11796555T ES2687706T3 ES 2687706 T3 ES2687706 T3 ES 2687706T3 ES 11796555 T ES11796555 T ES 11796555T ES 2687706 T3 ES2687706 T3 ES 2687706T3
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
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- General Health & Medical Sciences (AREA)
- Virology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Communicable Diseases (AREA)
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- Biotechnology (AREA)
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- Mycology (AREA)
- Inorganic Chemistry (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
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Applications Claiming Priority (7)
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| US35597810P | 2010-06-17 | 2010-06-17 | |
| US355978P | 2010-06-17 | ||
| US201161443103P | 2011-02-15 | 2011-02-15 | |
| US201161443103P | 2011-02-15 | ||
| US201161445455P | 2011-02-22 | 2011-02-22 | |
| US201161445455P | 2011-02-22 | ||
| PCT/US2011/040982 WO2011160083A1 (en) | 2010-06-17 | 2011-06-17 | Antibodies useful in passive influenza immuization |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2687706T3 true ES2687706T3 (es) | 2018-10-26 |
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| ES11796555.8T Active ES2687706T3 (es) | 2010-06-17 | 2011-06-17 | Anticuerpos útiles en la inmunización pasiva contra la gripe |
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| EP (1) | EP2582721B1 (OSRAM) |
| JP (1) | JP6050747B2 (OSRAM) |
| KR (1) | KR101849738B1 (OSRAM) |
| CN (2) | CN103209994B (OSRAM) |
| AU (2) | AU2011268072C1 (OSRAM) |
| BR (1) | BR112012032185A2 (OSRAM) |
| CA (1) | CA2839421C (OSRAM) |
| DK (1) | DK2582721T3 (OSRAM) |
| ES (1) | ES2687706T3 (OSRAM) |
| RU (1) | RU2635999C2 (OSRAM) |
| WO (1) | WO2011160083A1 (OSRAM) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
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| US10654915B2 (en) | 2011-12-05 | 2020-05-19 | Trellis Bioscience, Llc | Antibodies useful in passive influenza immunization |
| US9969794B2 (en) | 2012-05-10 | 2018-05-15 | Visterra, Inc. | HA binding agents |
| JP6386465B2 (ja) | 2012-11-13 | 2018-09-05 | ジェネンテック， インコーポレイテッド | 抗ヘマグルチニン抗体及び使用方法 |
| BR112015022623A2 (pt) | 2013-03-14 | 2017-07-18 | Contrafect Corp | composição e métodos baseados em anticorpos neutralizantes, administrados por via intranasal para eficácia terapêutica melhorada |
| US10639370B2 (en) | 2014-02-04 | 2020-05-05 | Contrafect Corporation | Antibodies useful in passive influenza immunization, and compositions, combinations and methods for use thereof |
| CN106795216B (zh) * | 2014-02-04 | 2021-04-20 | 抗非特公司 | 可用于被动流感免疫的抗体及其组合物、组合和使用方法 |
| EP3119802B1 (en) * | 2014-03-20 | 2019-12-04 | InflaRx GmbH | Inhibitors of c5a for the treatment of viral pneumonia |
| TWI701258B (zh) | 2014-12-19 | 2020-08-11 | 美商再生元醫藥公司 | 流行性感冒病毒血球凝集素之人類抗體 |
| EP3374390A1 (en) | 2015-11-13 | 2018-09-19 | Visterra, Inc. | Compositions and methods for treating and preventing influenza |
| AU2017222564A1 (en) | 2016-02-24 | 2018-09-06 | Visterra, Inc. | Formulations of antibody molecules to influenza virus |
| SG10201912842VA (en) | 2016-07-14 | 2020-02-27 | Bioarctic Ab | Brain delivery protein |
| US20210052719A1 (en) * | 2017-12-29 | 2021-02-25 | Development Center For Biotechnology | A universal vaccine against influenza |
| MX2020007772A (es) | 2018-01-26 | 2020-09-18 | Regeneron Pharma | Anticuerpos humanos contra hemaglutinina de influenza. |
| US11230593B2 (en) | 2019-03-25 | 2022-01-25 | Visterra, Inc. | Compositions and methods for treating and preventing influenza |
Family Cites Families (18)
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| US6235708B1 (en) | 1998-11-20 | 2001-05-22 | Zymogenetics, Inc | Testis-specific cystatin-like protein cystatin T |
| US20020006656A1 (en) | 1999-12-23 | 2002-01-17 | Holloway James L. | Zcys5: a member of the cystatin superfamily |
| WO2003080672A1 (en) | 2002-03-22 | 2003-10-02 | Aprogen, Inc. | Humanized antibody and process for preparing same |
| JP2006519775A (ja) | 2003-03-07 | 2006-08-31 | メルク エンド カムパニー インコーポレーテッド | インフルエンザウイルスワクチン |
| AU2004260884B2 (en) * | 2003-07-22 | 2009-11-19 | Crucell Holland B.V. | Binding molecules against SARS-coronavirus and uses thereof |
| RU2366662C2 (ru) * | 2003-07-23 | 2009-09-10 | Фуджирибайо Инк. | Моноклональное антитело к вирусу типа а гриппа и устройство для иммунного анализа с использованием антитела |
| US7413868B2 (en) | 2003-11-05 | 2008-08-19 | Trellis Bioscience, Inc. | Use of particulate labels in bioanalyte detection methods |
| EP2522678A1 (en) | 2006-05-15 | 2012-11-14 | Sea Lane Biotechnologies, LLC | Neutralizing antibodies to influenza viruses |
| HRP20130163T1 (hr) * | 2006-09-07 | 2013-03-31 | Crucell Holland B.V. | Ljudske molekule za vezanje koje mogu neutralizirati virus influence h5n1 i njihova uporaba |
| NO347649B1 (no) * | 2006-12-14 | 2024-02-12 | Regeneron Pharma | Humant antistoff eller antistoff fragment som spesifikt binder human deltaliknende ligand 4 (hDII4), nukleinsyremolekyl som koder for slike og vektor og vert-vektorsystemer, samt fremgangsmåte for fremstilling, sammensetning og anvendelse. |
| WO2009079259A2 (en) * | 2007-12-06 | 2009-06-25 | Dana-Farber Cancer Institute, Inc. | Antibodies against influenza virus and methods of use thereof |
| CN102046656A (zh) * | 2008-03-28 | 2011-05-04 | 航道生物技术有限责任公司 | 针对病毒抗原的中和性分子 |
| RU2553325C2 (ru) * | 2008-07-25 | 2015-06-10 | Институт Фо Ресёч Ин Биомедицин | Нейтрализующие антитела против вируса гриппа а и их использование |
| CL2009001735A1 (es) * | 2008-08-19 | 2010-02-19 | Regeneron Pharma | Anticuerpo humano o fragmento de union a antigeno del mismo que une e inhibe actividad de ligando del activador del receptor de nf-kb (rankl); adn codificante; vector de expresion; metodo para producir dicho anticuerpo; composicion farmaceutica que lo comprende; uso para atenuar o inhibir enfermedad o condicion mediada por rankl |
| SG172333A1 (en) | 2008-12-24 | 2011-07-28 | Temasek Life Sciences Lab Ltd | Monoclonal antibodies specific to the fusion peptide from hemagglutinin from influenza a viruses and uses thereof |
| SI2552485T1 (sl) | 2010-03-26 | 2017-05-31 | Pomona Ricerca S.R.L. | Imunoglobulini polne dolžine igg izotipa, sposobni prepoznave heteropodtipskega nevtralizacijskega epitopa na hemagglutininskem izvornem področju in njih uporaba kot zdravilo proti gripi |
| US8900590B2 (en) * | 2010-08-12 | 2014-12-02 | Theraclone Sciences, Inc. | Anti-hemagglutinin antibody compositions and methods of use thereof |
| WO2012045001A2 (en) * | 2010-09-30 | 2012-04-05 | Vanderbilt University | Influenza virus antibodies and immunogens and uses therefor |
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- 2011-06-17 CN CN201610806357.8A patent/CN106397584A/zh active Pending
- 2011-06-17 RU RU2013102073A patent/RU2635999C2/ru active
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- 2011-06-17 BR BR112012032185A patent/BR112012032185A2/pt not_active IP Right Cessation
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Also Published As
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| AU2017203924B2 (en) | 2019-08-08 |
| EP2582721A1 (en) | 2013-04-24 |
| DK2582721T3 (en) | 2018-10-01 |
| EP2582721B1 (en) | 2018-08-22 |
| CA2839421A1 (en) | 2011-12-22 |
| BR112012032185A2 (pt) | 2016-10-11 |
| KR20130137584A (ko) | 2013-12-17 |
| CA2839421C (en) | 2019-12-03 |
| AU2011268072B2 (en) | 2017-03-09 |
| CN103209994B (zh) | 2016-10-12 |
| US20120020971A1 (en) | 2012-01-26 |
| US10676520B2 (en) | 2020-06-09 |
| AU2011268072C1 (en) | 2017-10-19 |
| KR101849738B1 (ko) | 2018-04-17 |
| RU2013102073A (ru) | 2014-07-27 |
| CN106397584A (zh) | 2017-02-15 |
| AU2011268072A1 (en) | 2013-01-31 |
| JP6050747B2 (ja) | 2016-12-21 |
| AU2011268072A2 (en) | 2013-02-28 |
| WO2011160083A1 (en) | 2011-12-22 |
| EP2582721A4 (en) | 2013-11-20 |
| RU2635999C2 (ru) | 2017-11-17 |
| JP2013531993A (ja) | 2013-08-15 |
| AU2017203924A1 (en) | 2017-07-06 |
| CN103209994A (zh) | 2013-07-17 |
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