ES2660415T3 - Kit cerrado para contención y estabilización de tejidos para diagnósticos moleculares e histopatológicos - Google Patents
Kit cerrado para contención y estabilización de tejidos para diagnósticos moleculares e histopatológicos Download PDFInfo
- Publication number
- ES2660415T3 ES2660415T3 ES08841406.5T ES08841406T ES2660415T3 ES 2660415 T3 ES2660415 T3 ES 2660415T3 ES 08841406 T ES08841406 T ES 08841406T ES 2660415 T3 ES2660415 T3 ES 2660415T3
- Authority
- ES
- Spain
- Prior art keywords
- container
- hole
- fluid
- sample holder
- injection device
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 230000006641 stabilisation Effects 0.000 title description 4
- 238000011105 stabilization Methods 0.000 title description 4
- 239000000523 sample Substances 0.000 claims abstract description 140
- 239000012530 fluid Substances 0.000 claims abstract description 61
- 238000002347 injection Methods 0.000 claims abstract description 59
- 239000007924 injection Substances 0.000 claims abstract description 59
- 239000012472 biological sample Substances 0.000 claims abstract description 15
- 230000008878 coupling Effects 0.000 claims description 7
- 238000010168 coupling process Methods 0.000 claims description 7
- 238000005859 coupling reaction Methods 0.000 claims description 7
- 238000009423 ventilation Methods 0.000 claims description 7
- 239000003153 chemical reaction reagent Substances 0.000 description 45
- 239000000243 solution Substances 0.000 description 23
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 description 12
- 239000000834 fixative Substances 0.000 description 11
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 10
- WSFSSNUMVMOOMR-UHFFFAOYSA-N Formaldehyde Chemical compound O=C WSFSSNUMVMOOMR-UHFFFAOYSA-N 0.000 description 8
- 238000003860 storage Methods 0.000 description 6
- 238000002405 diagnostic procedure Methods 0.000 description 5
- 238000000034 method Methods 0.000 description 5
- HEDRZPFGACZZDS-UHFFFAOYSA-N Chloroform Chemical compound ClC(Cl)Cl HEDRZPFGACZZDS-UHFFFAOYSA-N 0.000 description 4
- 239000007788 liquid Substances 0.000 description 4
- 150000007523 nucleic acids Chemical class 0.000 description 4
- 102000039446 nucleic acids Human genes 0.000 description 4
- 108020004707 nucleic acids Proteins 0.000 description 4
- 230000008569 process Effects 0.000 description 4
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 description 3
- 201000010099 disease Diseases 0.000 description 3
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 3
- 239000000463 material Substances 0.000 description 3
- 239000003381 stabilizer Substances 0.000 description 3
- 238000012360 testing method Methods 0.000 description 3
- CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 description 2
- 238000003745 diagnosis Methods 0.000 description 2
- 230000007246 mechanism Effects 0.000 description 2
- 239000000203 mixture Substances 0.000 description 2
- 230000007704 transition Effects 0.000 description 2
- 150000001298 alcohols Chemical class 0.000 description 1
- 239000003708 ampul Substances 0.000 description 1
- 230000004888 barrier function Effects 0.000 description 1
- 230000015556 catabolic process Effects 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 238000004891 communication Methods 0.000 description 1
- 238000011109 contamination Methods 0.000 description 1
- 238000012864 cross contamination Methods 0.000 description 1
- 230000002380 cytological effect Effects 0.000 description 1
- 238000006731 degradation reaction Methods 0.000 description 1
- 238000007435 diagnostic evaluation Methods 0.000 description 1
- 230000006353 environmental stress Effects 0.000 description 1
- 230000002068 genetic effect Effects 0.000 description 1
- 239000011521 glass Substances 0.000 description 1
- 238000002372 labelling Methods 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 229940127554 medical product Drugs 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 238000013518 transcription Methods 0.000 description 1
- 230000035897 transcription Effects 0.000 description 1
- 238000012546 transfer Methods 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
- 238000009736 wetting Methods 0.000 description 1
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/508—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/30—Staining; Impregnating ; Fixation; Dehydration; Multistep processes for preparing samples of tissue, cell or nucleic acid material and the like for analysis
- G01N1/31—Apparatus therefor
- G01N1/312—Apparatus therefor for samples mounted on planar substrates
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/36—Embedding or analogous mounting of samples
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/02—Adapting objects or devices to another
- B01L2200/026—Fluid interfacing between devices or objects, e.g. connectors, inlet details
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/04—Closures and closing means
- B01L2300/041—Connecting closures to device or container
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/04—Closures and closing means
- B01L2300/046—Function or devices integrated in the closure
- B01L2300/047—Additional chamber, reservoir
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/04—Closures and closing means
- B01L2300/046—Function or devices integrated in the closure
- B01L2300/048—Function or devices integrated in the closure enabling gas exchange, e.g. vents
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/06—Auxiliary integrated devices, integrated components
- B01L2300/0609—Holders integrated in container to position an object
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Analytical Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Hematology (AREA)
- Clinical Laboratory Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Sampling And Sample Adjustment (AREA)
- Packages (AREA)
- Devices For Use In Laboratory Experiments (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US98204907P | 2007-10-23 | 2007-10-23 | |
US982049P | 2007-10-23 | ||
PCT/US2008/080995 WO2009055595A1 (en) | 2007-10-23 | 2008-10-23 | Closed kit for tissue containment and stabilization for molecular and histopathology diagnostics |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2660415T3 true ES2660415T3 (es) | 2018-03-22 |
Family
ID=40254381
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES08841406.5T Active ES2660415T3 (es) | 2007-10-23 | 2008-10-23 | Kit cerrado para contención y estabilización de tejidos para diagnósticos moleculares e histopatológicos |
ES17190999T Active ES2752754T3 (es) | 2007-10-23 | 2008-10-23 | Kit cerrado para contención y estabilización de tejidos para diagnósticos moleculares e histopatológicos |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES17190999T Active ES2752754T3 (es) | 2007-10-23 | 2008-10-23 | Kit cerrado para contención y estabilización de tejidos para diagnósticos moleculares e histopatológicos |
Country Status (10)
Country | Link |
---|---|
US (2) | US20090105611A1 (pt) |
EP (2) | EP2214826B1 (pt) |
JP (1) | JP5124651B2 (pt) |
CN (1) | CN101835538B (pt) |
AU (1) | AU2008316775B2 (pt) |
BR (1) | BRPI0818614B1 (pt) |
CA (1) | CA2700914C (pt) |
ES (2) | ES2660415T3 (pt) |
MX (1) | MX2010004419A (pt) |
WO (1) | WO2009055595A1 (pt) |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP5211170B2 (ja) | 2007-10-23 | 2013-06-12 | ベクトン・ディキンソン・アンド・カンパニー | 破損し易い膜を組み込んだ分子的及び組織的診断のための組織容器 |
CA2911481C (en) * | 2007-10-23 | 2017-07-04 | Becton, Dickinson And Company | Container system for tissue stabilization for molecular and histopathology diagnostics |
BRPI0818876B1 (pt) | 2007-10-23 | 2019-12-17 | Becton Dickinson Co | conjunto de recipiente e método associado para alojar uma amostra biológica |
US20090105611A1 (en) | 2007-10-23 | 2009-04-23 | Becton, Dickinson And Company | Closed Kit for Tissue Containment and Stabilization for Molecular and Histopathology Diagnostics |
CN102466581B (zh) * | 2010-11-09 | 2015-09-30 | 艾博生物医药(杭州)有限公司 | 一种装置 |
CN113941381A (zh) * | 2015-02-20 | 2022-01-18 | 文塔纳医疗系统公司 | 用于储存和运输浸入在流体中的组织样本的组件 |
WO2017156375A1 (en) * | 2016-03-10 | 2017-09-14 | Arthrex, Inc. | Systems and methods for preparing a thrombin serum |
EP3426400B1 (en) * | 2016-03-10 | 2020-09-02 | Arthrex Inc | System for preparing protein enhanced serums |
EP3385697A1 (en) * | 2017-04-04 | 2018-10-10 | Raman Health Technologies, S.L | Sample holder |
DE102017119140B3 (de) * | 2017-08-22 | 2019-02-28 | Thomas Märsch | Kassette zum Einlegen einer Gewebeprobe |
CN108990961A (zh) * | 2018-05-22 | 2018-12-14 | 河南中医药大学 | 容纳和稳定组织以用于分子和组织病理学诊断的密闭组件 |
EP4361054A2 (en) * | 2018-07-18 | 2024-05-01 | Bicocchi, Enrico | System and method for preserving a surgically explanted tissue sample |
EP3620772B1 (en) * | 2018-09-06 | 2021-10-13 | Milestone S.r.l. | System and method for filling a closed container with a fixative solution |
US20200309649A1 (en) * | 2019-03-08 | 2020-10-01 | Samantree Medical Sa | Receptacles for staining and/or rinsing samples and methods of their use |
CN109975347B (zh) * | 2019-03-13 | 2021-05-07 | 安徽理工大学 | 一种热分析用坩埚的乳胶状试样填充方法及辅助装置 |
CN112224667A (zh) * | 2019-07-15 | 2021-01-15 | 京东方科技集团股份有限公司 | 包装结构及利用其包装膜片的方法 |
US12054320B2 (en) | 2019-09-23 | 2024-08-06 | Cepheid | Multi-chambered lid apparatus with reagent port |
CN114430701B (zh) * | 2019-09-23 | 2024-09-13 | 塞弗德公司 | 具有试剂端口的多腔室盖装置 |
GB2600091A (en) * | 2020-10-12 | 2022-04-27 | Cellpath Ltd | Cassette assembly and processing method |
CN112924364B (zh) * | 2021-01-22 | 2024-07-23 | 贝克曼库尔特生物科技(苏州)有限公司 | 喷嘴、载体、喷嘴组件及样本处理仪 |
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US20080025877A1 (en) * | 2006-05-15 | 2008-01-31 | Alley Kenneth A | Specimen collection and testing apparatus |
ES2357169T3 (es) * | 2006-10-06 | 2011-04-19 | Bard Peripheral Vascular, Inc. | Sistema de manipulación de tejidos con exposición reducida del operador. |
KR20100016517A (ko) | 2007-04-16 | 2010-02-12 | 오라슈어 테크놀로지스, 인크. | 샘플 수집기 |
US20090105611A1 (en) | 2007-10-23 | 2009-04-23 | Becton, Dickinson And Company | Closed Kit for Tissue Containment and Stabilization for Molecular and Histopathology Diagnostics |
BRPI0818876B1 (pt) | 2007-10-23 | 2019-12-17 | Becton Dickinson Co | conjunto de recipiente e método associado para alojar uma amostra biológica |
CA2911481C (en) | 2007-10-23 | 2017-07-04 | Becton, Dickinson And Company | Container system for tissue stabilization for molecular and histopathology diagnostics |
JP5211170B2 (ja) | 2007-10-23 | 2013-06-12 | ベクトン・ディキンソン・アンド・カンパニー | 破損し易い膜を組み込んだ分子的及び組織的診断のための組織容器 |
BRPI0818068B1 (pt) | 2007-10-23 | 2019-06-25 | Becton, Dickinson And Company | Recipiente para tecido com deslocamento de fluido para diagnóstico molecular e histológico |
JP2011505550A (ja) | 2007-11-20 | 2011-02-24 | スリーエム イノベイティブ プロパティズ カンパニー | 試料を調製及び収集するためのシステム及び方法 |
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- 2008-10-23 ES ES08841406.5T patent/ES2660415T3/es active Active
- 2008-10-23 BR BRPI0818614-6A patent/BRPI0818614B1/pt active IP Right Grant
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- 2008-10-23 EP EP08841406.5A patent/EP2214826B1/en active Active
- 2008-10-23 EP EP17190999.7A patent/EP3284537B1/en active Active
- 2008-10-23 CN CN2008801130043A patent/CN101835538B/zh active Active
- 2008-10-23 WO PCT/US2008/080995 patent/WO2009055595A1/en active Application Filing
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ES2752754T3 (es) | 2020-04-06 |
EP3284537B1 (en) | 2019-08-28 |
US20090105611A1 (en) | 2009-04-23 |
JP5124651B2 (ja) | 2013-01-23 |
AU2008316775A1 (en) | 2009-04-30 |
EP3284537A1 (en) | 2018-02-21 |
AU2008316775B2 (en) | 2011-12-08 |
CN101835538A (zh) | 2010-09-15 |
CA2700914A1 (en) | 2009-04-30 |
CN101835538B (zh) | 2013-09-04 |
EP2214826B1 (en) | 2017-11-29 |
US10639636B2 (en) | 2020-05-05 |
EP2214826A1 (en) | 2010-08-11 |
BRPI0818614A2 (pt) | 2015-04-07 |
CA2700914C (en) | 2013-05-14 |
US20170361317A1 (en) | 2017-12-21 |
JP2011502253A (ja) | 2011-01-20 |
WO2009055595A1 (en) | 2009-04-30 |
MX2010004419A (es) | 2010-05-05 |
BRPI0818614B1 (pt) | 2019-06-25 |
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