ES2596402T3 - Proteasas estabilizadas para su uso en el cuidado de la piel - Google Patents

Proteasas estabilizadas para su uso en el cuidado de la piel Download PDF

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Publication number
ES2596402T3
ES2596402T3 ES11735144.5T ES11735144T ES2596402T3 ES 2596402 T3 ES2596402 T3 ES 2596402T3 ES 11735144 T ES11735144 T ES 11735144T ES 2596402 T3 ES2596402 T3 ES 2596402T3
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Spain
Prior art keywords
protease
papain
stabilized
dma
weeks
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ES11735144.5T
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English (en)
Spanish (es)
Inventor
Manasi Chavan
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BASF Corp
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BASF Corp
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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64Proteins; Peptides; Derivatives or degradation products thereof
    • A61K8/66Enzymes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46Hydrolases (3)
    • A61K38/48Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/4873Cysteine endopeptidases (3.4.22), e.g. stem bromelain, papain, ficin, cathepsin H
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/58Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. poly[meth]acrylate, polyacrylamide, polystyrene, polyvinylpyrrolidone, polyvinylalcohol or polystyrene sulfonic acid resin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/007Preparations for dry skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/08Anti-ageing preparations
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/48Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/63Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from plants
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/96Stabilising an enzyme by forming an adduct or a composition; Forming enzyme conjugates
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y304/00Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/22Cysteine endopeptidases (3.4.22)
    • C12Y304/22002Papain (3.4.22.2)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/57Compounds covalently linked to a(n inert) carrier molecule, e.g. conjugates, pro-fragrances

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Gerontology & Geriatric Medicine (AREA)
  • Immunology (AREA)
  • Birds (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Botany (AREA)
  • Cosmetics (AREA)
  • Medicinal Preparation (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
ES11735144.5T 2010-01-19 2011-01-19 Proteasas estabilizadas para su uso en el cuidado de la piel Active ES2596402T3 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US29605210P 2010-01-19 2010-01-19
US296052P 2010-01-19
PCT/US2011/021773 WO2011091084A2 (en) 2010-01-19 2011-01-19 Stabilized proteases for use in skin care

Publications (1)

Publication Number Publication Date
ES2596402T3 true ES2596402T3 (es) 2017-01-09

Family

ID=44277727

Family Applications (1)

Application Number Title Priority Date Filing Date
ES11735144.5T Active ES2596402T3 (es) 2010-01-19 2011-01-19 Proteasas estabilizadas para su uso en el cuidado de la piel

Country Status (7)

Country Link
US (1) US8778336B2 (enExample)
EP (1) EP2525828B1 (enExample)
JP (1) JP5848260B2 (enExample)
KR (1) KR101759755B1 (enExample)
CN (2) CN106480008A (enExample)
ES (1) ES2596402T3 (enExample)
WO (1) WO2011091084A2 (enExample)

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WO2013025986A2 (en) 2011-08-17 2013-02-21 Basf Corporation Marine based cosmetic active ingredients and use thereof
JP6162449B2 (ja) * 2012-03-28 2017-07-12 株式会社コーセー (カルボマー/パパイン)クロスポリマー含有組成物
JP5912759B2 (ja) * 2012-03-29 2016-04-27 株式会社コーセー (カルボマー/パパイン)クロスポリマー含有組成物
KR101936687B1 (ko) * 2012-04-06 2019-01-11 (주)아모레퍼시픽 파우더 타입 화장료 조성물
GB201305023D0 (en) 2013-03-19 2013-05-01 Biocant Associa O De Transfer Ncia De Tecnologia Aspartic proteases
JP6292602B2 (ja) * 2013-04-15 2018-03-14 学校法人神奈川大学 濡れ性低減又は増加に用いられる製剤及びその製造用原料、並びに濡れ性を低減又は増加させる方法
JP6182975B2 (ja) * 2013-05-21 2017-08-23 日油株式会社 ジェル状皮膚化粧料
CN105053812A (zh) * 2015-08-18 2015-11-18 凤台县龙泰面粉有限责任公司 一种高蛋白含量木耳莲子补血面粉及其制备方法
CN105077064A (zh) * 2015-08-18 2015-11-25 凤台县永新工贸有限责任公司 一种具有健脾益肾功效的蔬菜面粉及其制备方法
CN105165953A (zh) * 2015-08-18 2015-12-23 凤台县龙泰面粉有限责任公司 一种红曲米健胃消食面粉及其制备方法
CN105145717A (zh) * 2015-08-18 2015-12-16 凤台县永新工贸有限责任公司 一种高血脂人群食用的降脂面粉及其制备方法
CN105192017A (zh) * 2015-08-18 2015-12-30 凤台县龙泰面粉有限责任公司 一种蓝莓枸杞明目保健面粉及其制备方法
CN105053809A (zh) * 2015-08-18 2015-11-18 凤台县永新工贸有限责任公司 一种香菇鸡肉味营养面粉及其制备方法
CN105053811A (zh) * 2015-08-18 2015-11-18 凤台县龙泰面粉有限责任公司 一种咖喱味虾仁面粉及其制备方法
CN105211695A (zh) * 2015-09-30 2016-01-06 安徽省达亿粮油食品有限公司 一种山慈菇木瓜益气生津保健面粉及其制备方法
CN105166657A (zh) * 2015-09-30 2015-12-23 安徽省达亿粮油食品有限公司 一种补肾强筋保健面粉及其制备方法
CN105166660A (zh) * 2015-09-30 2015-12-23 安徽省达亿粮油食品有限公司 一种益气健脾保健面粉及其制备方法
CN105211696A (zh) * 2015-09-30 2016-01-06 安徽省达亿粮油食品有限公司 一种苦瓜杏仁营养面粉及其制备方法
CN105166658A (zh) * 2015-09-30 2015-12-23 安徽省达亿粮油食品有限公司 一种辣木籽健胃消食面粉及其制备方法
KR102376345B1 (ko) * 2016-01-31 2022-03-18 메디운드 리미티드 상처 치료용 괴사조직제거 조성물
CN109475608A (zh) * 2016-04-18 2019-03-15 麦迪伍德有限公司 慢性伤口清创的方法
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CN109248326A (zh) * 2018-11-09 2019-01-22 深圳先进技术研究院 一种骨靶向纳米粒递送系统及其制备方法
US20230142078A1 (en) * 2019-10-09 2023-05-11 Phoenix Eagle Company Pty Ltd Enhancement and stabilisation of proteolytic activity of proteases
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Also Published As

Publication number Publication date
US8778336B2 (en) 2014-07-15
CN102802670A (zh) 2012-11-28
CN106480008A (zh) 2017-03-08
KR20120118040A (ko) 2012-10-25
KR101759755B1 (ko) 2017-07-19
US20110177052A1 (en) 2011-07-21
EP2525828B1 (en) 2016-07-06
EP2525828A4 (en) 2013-07-31
WO2011091084A2 (en) 2011-07-28
JP5848260B2 (ja) 2016-01-27
JP2013517328A (ja) 2013-05-16
EP2525828A2 (en) 2012-11-28
WO2011091084A3 (en) 2011-12-29

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