JP5848260B2 - スキンケアでの利用のための安定化プロテアーゼ - Google Patents

スキンケアでの利用のための安定化プロテアーゼ Download PDF

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JP5848260B2
JP5848260B2 JP2012550094A JP2012550094A JP5848260B2 JP 5848260 B2 JP5848260 B2 JP 5848260B2 JP 2012550094 A JP2012550094 A JP 2012550094A JP 2012550094 A JP2012550094 A JP 2012550094A JP 5848260 B2 JP5848260 B2 JP 5848260B2
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protease
cross
stabilized
papain
amine
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JP2013517328A5 (enExample
JP2013517328A (ja
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チャバン，マナシ
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BASF Corp
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BASF Corp
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/96—Stabilising an enzyme by forming an adduct or a composition; Forming enzyme conjugates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/4873—Cysteine endopeptidases (3.4.22), e.g. stem bromelain, papain, ficin, cathepsin H
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/58—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. poly[meth]acrylate, polyacrylamide, polystyrene, polyvinylpyrrolidone, polyvinylalcohol or polystyrene sulfonic acid resin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
    • A61K8/66—Enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/007—Preparations for dry skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/08—Anti-ageing preparations
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/63—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from plants
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/22—Cysteine endopeptidases (3.4.22)
    • C12Y304/22002—Papain (3.4.22.2)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/57—Compounds covalently linked to a(n inert) carrier molecule, e.g. conjugates, pro-fragrances

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Gerontology & Geriatric Medicine (AREA)
  • Immunology (AREA)
  • Birds (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Botany (AREA)
  • Cosmetics (AREA)
  • Medicinal Preparation (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
JP2012550094A 2010-01-19 2011-01-19 スキンケアでの利用のための安定化プロテアーゼ Active JP5848260B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US29605210P 2010-01-19 2010-01-19
US61/296,052 2010-01-19
PCT/US2011/021773 WO2011091084A2 (en) 2010-01-19 2011-01-19 Stabilized proteases for use in skin care

Publications (3)

Publication Number Publication Date
JP2013517328A JP2013517328A (ja) 2013-05-16
JP2013517328A5 JP2013517328A5 (enExample) 2014-02-20
JP5848260B2 true JP5848260B2 (ja) 2016-01-27

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JP2012550094A Active JP5848260B2 (ja) 2010-01-19 2011-01-19 スキンケアでの利用のための安定化プロテアーゼ

Country Status (7)

Country Link
US (1) US8778336B2 (enExample)
EP (1) EP2525828B1 (enExample)
JP (1) JP5848260B2 (enExample)
KR (1) KR101759755B1 (enExample)
CN (2) CN106480008A (enExample)
ES (1) ES2596402T3 (enExample)
WO (1) WO2011091084A2 (enExample)

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WO2013025986A2 (en) 2011-08-17 2013-02-21 Basf Corporation Marine based cosmetic active ingredients and use thereof
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JP5912759B2 (ja) * 2012-03-29 2016-04-27 株式会社コーセー （カルボマー／パパイン）クロスポリマー含有組成物
KR101936687B1 (ko) * 2012-04-06 2019-01-11 (주)아모레퍼시픽 파우더 타입 화장료 조성물
GB201305023D0 (en) 2013-03-19 2013-05-01 Biocant Associa O De Transfer Ncia De Tecnologia Aspartic proteases
JP6292602B2 (ja) * 2013-04-15 2018-03-14 学校法人神奈川大学 濡れ性低減又は増加に用いられる製剤及びその製造用原料、並びに濡れ性を低減又は増加させる方法
JP6182975B2 (ja) * 2013-05-21 2017-08-23 日油株式会社 ジェル状皮膚化粧料
CN105053812A (zh) * 2015-08-18 2015-11-18 凤台县龙泰面粉有限责任公司 一种高蛋白含量木耳莲子补血面粉及其制备方法
CN105077064A (zh) * 2015-08-18 2015-11-25 凤台县永新工贸有限责任公司 一种具有健脾益肾功效的蔬菜面粉及其制备方法
CN105165953A (zh) * 2015-08-18 2015-12-23 凤台县龙泰面粉有限责任公司 一种红曲米健胃消食面粉及其制备方法
CN105145717A (zh) * 2015-08-18 2015-12-16 凤台县永新工贸有限责任公司 一种高血脂人群食用的降脂面粉及其制备方法
CN105192017A (zh) * 2015-08-18 2015-12-30 凤台县龙泰面粉有限责任公司 一种蓝莓枸杞明目保健面粉及其制备方法
CN105053809A (zh) * 2015-08-18 2015-11-18 凤台县永新工贸有限责任公司 一种香菇鸡肉味营养面粉及其制备方法
CN105053811A (zh) * 2015-08-18 2015-11-18 凤台县龙泰面粉有限责任公司 一种咖喱味虾仁面粉及其制备方法
CN105211695A (zh) * 2015-09-30 2016-01-06 安徽省达亿粮油食品有限公司 一种山慈菇木瓜益气生津保健面粉及其制备方法
CN105166657A (zh) * 2015-09-30 2015-12-23 安徽省达亿粮油食品有限公司 一种补肾强筋保健面粉及其制备方法
CN105166660A (zh) * 2015-09-30 2015-12-23 安徽省达亿粮油食品有限公司 一种益气健脾保健面粉及其制备方法
CN105211696A (zh) * 2015-09-30 2016-01-06 安徽省达亿粮油食品有限公司 一种苦瓜杏仁营养面粉及其制备方法
CN105166658A (zh) * 2015-09-30 2015-12-23 安徽省达亿粮油食品有限公司 一种辣木籽健胃消食面粉及其制备方法
KR102376345B1 (ko) * 2016-01-31 2022-03-18 메디운드 리미티드 상처 치료용 괴사조직제거 조성물
CN109475608A (zh) * 2016-04-18 2019-03-15 麦迪伍德有限公司 慢性伤口清创的方法
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CN109248326A (zh) * 2018-11-09 2019-01-22 深圳先进技术研究院 一种骨靶向纳米粒递送系统及其制备方法
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Also Published As

Publication number Publication date
US8778336B2 (en) 2014-07-15
CN102802670A (zh) 2012-11-28
CN106480008A (zh) 2017-03-08
KR20120118040A (ko) 2012-10-25
KR101759755B1 (ko) 2017-07-19
US20110177052A1 (en) 2011-07-21
EP2525828B1 (en) 2016-07-06
ES2596402T3 (es) 2017-01-09
EP2525828A4 (en) 2013-07-31
WO2011091084A2 (en) 2011-07-28
JP2013517328A (ja) 2013-05-16
EP2525828A2 (en) 2012-11-28
WO2011091084A3 (en) 2011-12-29

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