ES2582655T3 - Proteína linfopoyetina estromal tímica canina y usos de la misma - Google Patents

Proteína linfopoyetina estromal tímica canina y usos de la misma Download PDF

Info

Publication number
ES2582655T3
ES2582655T3 ES07867705.1T ES07867705T ES2582655T3 ES 2582655 T3 ES2582655 T3 ES 2582655T3 ES 07867705 T ES07867705 T ES 07867705T ES 2582655 T3 ES2582655 T3 ES 2582655T3
Authority
ES
Spain
Prior art keywords
seq
tslp
protein
amino acid
canine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES07867705.1T
Other languages
English (en)
Spanish (es)
Inventor
Jeanine D. Mattson
Daniel M. Gorman
Rene De Waal Malefyt
Mohamad A. Morsey
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Intervet International BV
Original Assignee
Intervet International BV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Intervet International BV filed Critical Intervet International BV
Application granted granted Critical
Publication of ES2582655T3 publication Critical patent/ES2582655T3/es
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/415—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants
    • C07K14/43—Sweetening agents, e.g. thaumatin, monellin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/20—Interleukins [IL]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/54—Interleukins [IL]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/54—Interleukins [IL]
    • C07K14/5418—IL-7
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/46—Hybrid immunoglobulins
    • C07K16/461—Igs containing Ig-regions, -domains or -residues form different species
    • C07K16/464—Igs containing CDR-residues from one specie grafted between FR-residues from another
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/53—DNA (RNA) vaccination
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
    • A61K2039/552—Veterinary vaccine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/33—Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/52—Assays involving cytokines
    • G01N2333/54—Interleukins [IL]
    • G01N2333/5418—IL-7
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/20—Dermatological disorders
    • G01N2800/202—Dermatitis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • Zoology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Toxicology (AREA)
  • Pulmonology (AREA)
  • Dermatology (AREA)
  • Transplantation (AREA)
  • Botany (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
ES07867705.1T 2006-12-14 2007-12-11 Proteína linfopoyetina estromal tímica canina y usos de la misma Active ES2582655T3 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US87513506P 2006-12-14 2006-12-14
US875135P 2006-12-14
PCT/US2007/025318 WO2008076255A2 (en) 2006-12-14 2007-12-11 Canine thymic stromal lymphopoietin protein and uses thereof

Publications (1)

Publication Number Publication Date
ES2582655T3 true ES2582655T3 (es) 2016-09-14

Family

ID=39430681

Family Applications (1)

Application Number Title Priority Date Filing Date
ES07867705.1T Active ES2582655T3 (es) 2006-12-14 2007-12-11 Proteína linfopoyetina estromal tímica canina y usos de la misma

Country Status (18)

Country Link
US (3) US7718772B2 (https=)
EP (1) EP2104683B1 (https=)
JP (4) JP2010512744A (https=)
KR (1) KR101525631B1 (https=)
CN (2) CN102584998B (https=)
AU (1) AU2007334531B2 (https=)
BR (1) BRPI0720001A2 (https=)
CA (1) CA2671865C (https=)
CO (1) CO6210756A2 (https=)
ES (1) ES2582655T3 (https=)
IL (2) IL199170A (https=)
IN (1) IN2009CN03372A (https=)
MX (1) MX2009006470A (https=)
NZ (1) NZ578352A (https=)
RU (2) RU2457217C2 (https=)
UA (3) UA120027C2 (https=)
WO (1) WO2008076255A2 (https=)
ZA (1) ZA200904152B (https=)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
UA120027C2 (uk) * 2006-12-14 2019-09-25 Шерінг-Плау Лтд. Ізольоване антитіло проти собачого тимусного стромального лімфопоетину (tslp)
JP5492158B2 (ja) 2011-08-24 2014-05-14 富士フイルム株式会社 ヒトｔｓｈ及び犬ｔｓｈに対する抗体
WO2013119419A1 (en) 2012-02-08 2013-08-15 North Carolina State University Treatment of allergic diseases with recombinant antibodies
AR090915A1 (es) 2012-05-04 2014-12-17 Intervet Int Bv Proteina de fusion de proteina linfopoyetina estromal timica canina con la region fc de igg
US20160052985A1 (en) * 2013-04-04 2016-02-25 Ieo - Istituto Europeo Di Oncologia Srl Thymic stromal lymphopoietin fragments and uses thereof
UA119328C2 (uk) * 2013-08-09 2019-06-10 Астеллас Фарма Інк. Антитіло до тslp-рецептора людини
CN106029697B (zh) 2013-12-20 2021-06-04 英特维特国际股份有限公司 具有经修饰的ch2-ch3序列的犬抗体
WO2015118124A1 (en) * 2014-02-06 2015-08-13 Vib Vzw Thymic stromal lymphopoietin receptor antagonist
CA2980087A1 (en) 2015-04-02 2016-10-06 Intervet International B.V. Antibodies to canine interleukin-4 receptor alpha
EA038332B1 (ru) 2015-09-09 2021-08-10 Новартис Аг Молекулы, связывающиеся с тимусным стромальным лимфопоэтином (tslp), и способы применения таких молекул
HRP20210650T1 (hr) 2015-09-09 2021-05-28 Novartis Ag Protutijela koja vežu timusni stromalni limfopoetin (tslp) i postupci uporabe protutijela
CA3005696A1 (en) 2015-12-18 2017-06-22 Intervet International B.V. Caninized human antibodies to human and canine il-4r alpha
US11091556B2 (en) 2015-12-18 2021-08-17 Intervet Inc. Caninized human antibodies to human IL-4R alpha
WO2018089335A1 (en) 2016-11-09 2018-05-17 North Carolina State University Treatment of allergic diseases with chimeric protein
US12060437B2 (en) 2018-03-23 2024-08-13 North Carolina State University Methods and compositions for antibody to high affinity receptor for IgE
CN115028722B (zh) * 2021-03-05 2024-09-03 拜西欧斯（北京）生物技术有限公司 抗tslp抗体及其制备方法和用途

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4281061A (en) 1979-07-27 1981-07-28 Syva Company Double antibody for enhanced sensitivity in immunoassay
ZA887773B (en) 1987-10-26 1989-07-26 Immunex Corp Interleukin-7
US5714585A (en) 1987-10-26 1998-02-03 Sterling Winthrop, Inc. Antibodies that are immunoreactive with interleukin-7
US5413914A (en) 1993-07-07 1995-05-09 The Regents Of The University Of Colorado Yeast assay to identify inhibitors of dibasic amino acid processing endoproteases
US6844170B1 (en) 1998-03-19 2005-01-18 Human Genome Sciences, Inc. Cytokine receptor common gamma chain like
US20030099947A1 (en) 1998-09-21 2003-05-29 Bazan J. Fernando Mammalian cytokines; related reagents and methods
DE69936105T3 (de) 1998-11-13 2017-07-27 Immunex Corporation Menschliche tslp nukleinsäuren und polypeptide
EP1140976A4 (en) 1998-12-30 2003-05-21 Millennium Pharm Inc SECRETED PROTEINS AND THEIR USES
GB9908533D0 (en) * 1999-04-14 1999-06-09 Novartis Ag Organic compounds
ES2391124T3 (es) 2000-06-28 2012-11-21 Amgen Inc. Moléculas de receptor de linfopoyetina estromal tímica y usos de las mismas
US6890734B2 (en) 2000-11-10 2005-05-10 Schering Corporation Nucleic acids encoding a cytokine receptor complex
SI1651247T1 (sl) * 2003-07-18 2009-02-28 Schering Corp Zdravljenje in diagnoza neoplazem z uporabo timusnega stromalnega limfopoietina
US20090156467A1 (en) * 2004-07-28 2009-06-18 Zhengbin Yao Thymic stromal lymphpoietin promoter and use therefor
SE532251C2 (sv) * 2006-11-28 2009-11-24 Theravac Pharmaceuticals Ab Nya formuleringar av TSLP för behandling av TH2-medierade inflammatoriska sjukdomar genom vaccinering
UA120027C2 (uk) 2006-12-14 2019-09-25 Шерінг-Плау Лтд. Ізольоване антитіло проти собачого тимусного стромального лімфопоетину (tslp)

Also Published As

Publication number Publication date
RU2012113162A (ru) 2013-10-20
US20110033478A1 (en) 2011-02-10
CA2671865C (en) 2017-01-10
US20130183291A1 (en) 2013-07-18
US7718772B2 (en) 2010-05-18
EP2104683B1 (en) 2016-05-25
BRPI0720001A2 (pt) 2013-12-24
AU2007334531B2 (en) 2012-04-12
MX2009006470A (es) 2009-06-26
UA120027C2 (uk) 2019-09-25
US8791242B2 (en) 2014-07-29
CA2671865A1 (en) 2008-06-26
JP2013048637A (ja) 2013-03-14
CN102584998B (zh) 2017-07-04
WO2008076255A2 (en) 2008-06-26
RU2617957C2 (ru) 2017-04-28
JP2012090647A (ja) 2012-05-17
UA108064C2 (uk) 2015-03-25
UA95329C2 (ru) 2011-07-25
JP6117767B2 (ja) 2017-04-19
RU2457217C2 (ru) 2012-07-27
JP2010512744A (ja) 2010-04-30
KR20090097921A (ko) 2009-09-16
US20080152620A1 (en) 2008-06-26
KR101525631B1 (ko) 2015-06-04
RU2009126617A (ru) 2011-01-20
WO2008076255A3 (en) 2008-09-18
JP5707380B2 (ja) 2015-04-30
CO6210756A2 (es) 2010-10-20
EP2104683A2 (en) 2009-09-30
US8076456B2 (en) 2011-12-13
CN101631800A (zh) 2010-01-20
CN101631800B (zh) 2012-12-05
IL199170A (en) 2015-04-30
JP2015107121A (ja) 2015-06-11
IN2009CN03372A (https=) 2015-08-07
NZ578352A (en) 2012-05-25
CN102584998A (zh) 2012-07-18
IL215507A0 (en) 2011-11-30
ZA200904152B (en) 2011-11-30
AU2007334531A1 (en) 2008-06-26

Similar Documents

Publication Publication Date Title
ES2582655T3 (es) Proteína linfopoyetina estromal tímica canina y usos de la misma
Tu et al. Transmembrane segments form tertiary hairpins in the folding vestibule of the ribosome
Bao et al. Highly efficient expression and purification system of small-size protein domains in Escherichia coli for biochemical characterization
EP2663642B1 (en) Treponema pallidum triplet antigen
ES2896100T3 (es) Dominio FKBP con sitio de reconocimiento de transglutaminasa
EP3383887B1 (fr) Polypeptides mutés de hev et leur utilisation pour le dosage d'anticorps anti-hev
CN101939330B (zh) 新型风疹e1包膜蛋白变体及其在检测抗风疹抗体中的用途
Kumar et al. Peptide-recombinant VP6 protein based enzyme immunoassay for the detection of group a rotaviruses in multiple host species
Mirzadeh et al. Production of refolded Toxoplasma gondii recombinant SAG1-related sequence 3 (SRS3) and its use for serodiagnosis of human toxoplasmosis
Allahyari et al. Production of in-vitro refolded and highly antigenic SAG1 for development of a sensitive and specific Toxoplasma IgG ELISA
CN110669109B (zh) 一种酶联标签短肽及其应用
Mirzadeh et al. Expression, purification and in vitro refolding of the recombinant truncated Saposin-like protein 2 antigen for development of diagnosis of human fascioliasis
Zhao et al. Prokaryotic expression, refolding, and purification of fragment 450–650 of the spike protein of SARS-coronavirus
JP4310608B2 (ja) Ｈｓｐ７０ファミリータンパク質基質結合ドメインフラグメントの利用方法
CN104610443A (zh) 一种高稳定性重组降钙素原、制备方法及用途
Käkönen et al. Purification and characterization of recombinant osteocalcin fusion protein expressed inEscherichia coli
CN113874384A (zh) 生产高度多样性肽文库和促进蛋白质折叠的方法
JP4193499B2 (ja) 組換え発光蛋白質およびその複合体
JP5614409B2 (ja) トキソカラ症を検出するための組換え抗原
JP7222511B2 (ja) ペプチド及びその利用
CN107344963A (zh) 体外重折叠波形蛋白的方法及其应用
CN110128549A (zh) 脱酰胺基麦胶蛋白多肽重组抗原、重组抗原表达基因、重组表达载体及其制备方法和应用
CN102796752A (zh) 原核来源的泛素样分子的应用
Richter et al. Site specific biotinylation of the human aldo/keto reductase AKR1A1 for immobilization
KR102259974B1 (ko) 재조합 항원을 이용하여 목적 항원 특이적인 항체를 제조하는 방법