ES2531483T3 - Péptidos HER-2 - Google Patents

Péptidos HER-2 Download PDF

Info

Publication number
ES2531483T3
ES2531483T3 ES06785065.1T ES06785065T ES2531483T3 ES 2531483 T3 ES2531483 T3 ES 2531483T3 ES 06785065 T ES06785065 T ES 06785065T ES 2531483 T3 ES2531483 T3 ES 2531483T3
Authority
ES
Spain
Prior art keywords
epitope
seq
peptides
epitopes
peptide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES06785065.1T
Other languages
English (en)
Spanish (es)
Inventor
Pravin T. P. Kaumaya
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ohio State University Research Foundation
Original Assignee
Ohio State University Research Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ohio State University Research Foundation filed Critical Ohio State University Research Foundation
Application granted granted Critical
Publication of ES2531483T3 publication Critical patent/ES2531483T3/es
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
    • A61K39/0011—Cancer antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/71—Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/82—Translation products from oncogenes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biophysics (AREA)
  • Oncology (AREA)
  • Biochemistry (AREA)
  • Epidemiology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Cell Biology (AREA)
  • Toxicology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
ES06785065.1T 2005-06-15 2006-06-15 Péptidos HER-2 Active ES2531483T3 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US69057405P 2005-06-15 2005-06-15
US690574P 2005-06-15
PCT/US2006/023672 WO2006138675A2 (en) 2005-06-15 2006-06-15 Her-2 peptides

Publications (1)

Publication Number Publication Date
ES2531483T3 true ES2531483T3 (es) 2015-03-16

Family

ID=37571268

Family Applications (1)

Application Number Title Priority Date Filing Date
ES06785065.1T Active ES2531483T3 (es) 2005-06-15 2006-06-15 Péptidos HER-2

Country Status (7)

Country Link
US (3) US7691396B2 (enExample)
EP (1) EP1912680B1 (enExample)
JP (2) JP5222134B2 (enExample)
AU (1) AU2006261342B2 (enExample)
CA (1) CA2612394C (enExample)
ES (1) ES2531483T3 (enExample)
WO (1) WO2006138675A2 (enExample)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU6620300A (en) * 1999-08-03 2001-02-19 Ohio State University, The Polypeptides and polynucleotides for enhancing immune reactivity to her-2 protein
WO2006138675A2 (en) 2005-06-15 2006-12-28 The Ohio State University Research Foundation Her-2 peptides
US8945573B2 (en) * 2005-09-08 2015-02-03 The Henry M. Jackson Foundation For The Advancement Of Military Medicine, Inc. Targeted identification of immunogenic peptides
WO2008097229A1 (en) * 2007-02-09 2008-08-14 The Government Of The Usa As Represented By The Secretary Of The Dept. Of Health And Human Services Method for spectroscopic quantitation of her-2 in biological samples
US20110044882A1 (en) * 2008-04-22 2011-02-24 David Buckley Method of making high purity lithium hydroxide and hydrochloric acid
US20100234283A1 (en) 2009-02-04 2010-09-16 The Ohio State University Research Foundation Immunogenic epitopes, peptidomimetics, and anti-peptide antibodies, and methods of their use
US9125848B2 (en) 2010-06-10 2015-09-08 The Cleveland Clinic Foundation Alpha lactalbumin immunization methods
CA2812948C (en) * 2010-09-28 2019-01-22 Nono Inc. Nd2 peptides and methods of treating neurological disease
WO2013158553A1 (en) 2012-04-16 2013-10-24 The Cleveland Clinic Foundation Multivalent breast cancer vaccine
WO2014131019A2 (en) 2013-02-25 2014-08-28 Ohio State Innovation Foundation Her-1, her-3 and igf-1r compositions and uses thereof
CN105017425B (zh) * 2014-04-30 2018-02-16 京天成生物技术(北京)有限公司 抗her2中和活性单克隆抗体及其应用
US20180327453A1 (en) * 2015-11-06 2018-11-15 Evorx Technologies, Inc. Her-2-specific cyclized supr peptides
EP3576764A4 (en) 2017-02-03 2020-12-16 The Medical College of Wisconsin, Inc. KRAS PEPTIDIC VACCINE COMPOSITIONS AND METHOD OF USE
WO2018183488A1 (en) * 2017-03-28 2018-10-04 Ohio State Innovation Foundation Human pd1 peptide vaccines and uses thereof
US20200179500A1 (en) * 2018-12-05 2020-06-11 Wayne State University Methods and immunogenic compositions relating to her2 with selective sequence modifications
EP3941947A4 (en) * 2019-03-22 2022-12-14 Olivia Newton-John Cancer Research Institute ANTI-HER2 BINDING MOLECULES
JP7749543B2 (ja) * 2019-09-17 2025-10-06 オハイオ・ステイト・イノベーション・ファウンデーション ヒト抗ｐｄ－ｌ１ペプチドワクチン及びその使用方法
CA3243636A1 (en) 2022-02-28 2023-08-31 Tridem Bioscience Gmbh & Co Kg CONJUGATED COMPRISING AT LEAST ONE β-GLUCANE OR ONE MANNANA
CN119019569B (zh) * 2024-08-19 2025-10-24 中国人民解放军陆军军医大学 一种可定向增强胸腺新生t细胞杀伤乳腺癌的多肽及其应用

Family Cites Families (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3040121B2 (ja) * 1988-01-12 2000-05-08 ジェネンテク，インコーポレイテッド 増殖因子レセプターの機能を阻害することにより腫瘍細胞を処置する方法
EP0474727B1 (en) * 1989-05-19 1997-07-23 Genentech, Inc. Her2 extracellular domain
ATE120860T1 (de) * 1990-01-26 1995-04-15 Washington Res Found Immunreaktivität gegenüber exprimierten aktivierten oncogenen zur diagnose und behandlung von bösartigen geschwülsten.
IL101943A0 (en) * 1991-05-24 1992-12-30 Genentech Inc Structure,production and use of heregulin
CA2138997C (en) 1992-06-25 2003-06-03 Jean-Paul Prieels Vaccine composition containing adjuvants
JPH08502253A (ja) 1992-09-28 1996-03-12 ファイザー・インコーポレイテッド 細胞媒介性免疫応答の増強方法
WO1994007530A1 (en) 1992-09-30 1994-04-14 The Ohio State University Research Foundation Vaccines and antigenic conjugates
US5869445A (en) * 1993-03-17 1999-02-09 University Of Washington Methods for eliciting or enhancing reactivity to HER-2/neu protein
US5801005A (en) * 1993-03-17 1998-09-01 University Of Washington Immune reactivity to HER-2/neu protein for diagnosis of malignancies in which the HER-2/neu oncogene is associated
GB9326253D0 (en) 1993-12-23 1994-02-23 Smithkline Beecham Biolog Vaccines
EP1167378B1 (en) 1994-07-15 2011-05-11 University of Iowa Research Foundation Immunomodulatory oligonucleotides
UA56132C2 (uk) 1995-04-25 2003-05-15 Смітклайн Бічем Байолоджікалс С.А. Композиція вакцини (варіанти), спосіб стабілізації qs21 відносно гідролізу (варіанти), спосіб приготування композиції вакцини
US6410022B1 (en) 1995-05-01 2002-06-25 Avant Immunotherapeutics, Inc. Modulation of cholesteryl ester transfer protein (CETP) activity
CA2251464A1 (en) 1996-04-03 1997-10-16 Pepresearch A/S Non-dendritic backbone peptide carrier
CN101412758A (zh) 1996-10-18 2009-04-22 基因技术股份有限公司 抗ErbB2抗体
CN1181422A (zh) * 1996-10-31 1998-05-13 上海市肿瘤研究所 与生长因子受体结合的多肽所构建的基因转移载体
DE69827138T2 (de) 1997-08-11 2006-02-23 Allergan, Inc., Irvine Steriles Retinoid enthaltendes biodegradierbares Implantat mit verbesserter Biokompatibilität und Verfahren zu dessen Herstellung
ZA9811162B (en) 1997-12-12 2000-06-07 Genentech Inc Treatment with anti-ERBB2 antibodies.
EP0953823A2 (en) 1998-05-01 1999-11-03 Aisin Cosmos R & D Co. Ltd. Micro yaw rate sensors
WO2000034337A1 (en) 1998-12-10 2000-06-15 Tsukuba Research Laboratory, Toagosei Co., Ltd. Humanized monoclonal antibodies against vascular endothelial cell growth factor
AU782325B2 (en) * 1999-05-14 2005-07-21 Genentech Inc. Treatment with anti-ErbB2 antibodies
AU6620300A (en) 1999-08-03 2001-02-19 Ohio State University, The Polypeptides and polynucleotides for enhancing immune reactivity to her-2 protein
US20030235594A1 (en) * 1999-09-14 2003-12-25 Antigen Express, Inc. Ii-Key/antigenic epitope hybrid peptide vaccines
US6432409B1 (en) * 1999-09-14 2002-08-13 Antigen Express, Inc. Hybrid peptides modulate the immune response
US20020193329A1 (en) * 2000-08-14 2002-12-19 Corixa Corporation Compositions and methods for the therapy and diagnosis of Her-2/neu-associated malignancies
GB0213878D0 (en) * 2002-06-17 2002-07-31 Protherics Plc Use
WO2004030616A2 (en) * 2002-09-17 2004-04-15 Antigen Express, Inc. Ii-KEY/ANTIGENIC EPITOPE HYBRID PEPTIDE VACCINES
CA2517518A1 (en) * 2003-03-04 2004-09-16 Intercell Ag Streptococcus pyogenes antigens
CN1812996A (zh) * 2003-06-25 2006-08-02 渥太华健康研究所 心营养素调节干细胞增殖的用途
DE602004028266D1 (de) * 2003-10-29 2010-09-02 Univ Ramot Angiogene peptide und ihre verwendungen
CA2555274A1 (en) 2004-02-05 2005-08-25 The Ohio State University Research Foundation Chimeric vegf peptides
SE0402565L (sv) 2004-10-19 2005-12-20 Mia Kumm Anordning och system för ventilation av tunnel vid brand
WO2006075486A1 (ja) * 2004-12-20 2006-07-20 Ajinomoto Co., Inc. ペプチド生成活性を有する変異型タンパク質
WO2006138675A2 (en) 2005-06-15 2006-12-28 The Ohio State University Research Foundation Her-2 peptides
US20100234283A1 (en) * 2009-02-04 2010-09-16 The Ohio State University Research Foundation Immunogenic epitopes, peptidomimetics, and anti-peptide antibodies, and methods of their use
JP5510272B2 (ja) 2010-06-21 2014-06-04 株式会社リコー 画像形成装置

Also Published As

Publication number Publication date
CA2612394C (en) 2017-02-21
US20140010831A1 (en) 2014-01-09
JP2009500298A (ja) 2009-01-08
EP1912680B1 (en) 2014-11-26
EP1912680A4 (en) 2010-09-22
JP2012136555A (ja) 2012-07-19
JP5542865B2 (ja) 2014-07-09
US9452204B2 (en) 2016-09-27
AU2006261342B2 (en) 2012-02-02
US7691396B2 (en) 2010-04-06
AU2006261342A1 (en) 2006-12-28
JP5222134B2 (ja) 2013-06-26
US8470333B2 (en) 2013-06-25
EP1912680A2 (en) 2008-04-23
WO2006138675A9 (en) 2010-01-28
US20110086055A1 (en) 2011-04-14
US20070060516A1 (en) 2007-03-15
WO2006138675A2 (en) 2006-12-28
CA2612394A1 (en) 2006-12-28

Similar Documents

Publication Publication Date Title
ES2531483T3 (es) Péptidos HER-2
ES2222728T3 (es) Procedimiento de vacunacion terapeutica.
ES2264419T3 (es) Vacunas y proteinas de streptococcus pneumoniae.
KR101914779B1 (ko) 노로 바이러스 백신을 생산하기 위한 재조합 발현 벡터
JPH04501719A (ja) ポリペプチド
JP5187883B2 (ja) 抗原ペプチドおよびその利用
EA016818B1 (ru) Слитые белки, содержащие антигены отторжения опухоли ny-eso-1 и lage-1
KR20230084478A (ko) 면역원성 코로나 바이러스 융합 단백질 및 관련 방법
ES2541779T3 (es) Péptidos VEGF quiméricos
CN113896805B (zh) 一种vegf-crm197重组融合蛋白疫苗及其制备方法和应用
CN119770633A (zh) 一种改进型多肽肿瘤疫苗组成与应用
CN107365367A (zh) A型口蹄疫病毒vp1蛋白抗原表位基因多肽及其应用
JP4838238B2 (ja) 組換え走化抗原遺伝子ワクチン
JP4651495B2 (ja) Ｉｓｇ１５タンパク質と特異的に反応するモノクローナル抗体及びそれを産生するハイブリドーマ並びに癌およびウイルス感染の検出方法
CN103290047A (zh) 一种快速制备植物富含亮氨酸的单跨膜受体蛋白激酶多克隆抗体的方法和应用
US20230054648A1 (en) Chimeric immunogens and methods for making polyclonal antibodies against specific epitopes
CN119462855B (zh) 一种GnRH核酸疫苗
ES2288884T3 (es) Acido nucleico que codifica una proteina de la familia ctage, su uso y produccion.
Ren et al. Improved method to raise polyclonal antibody using enhanced green fluorescent protein transgenic mice
Algate et al. Antigens
CN1408866A (zh) 人受精促进肽受体tcp11及其编码序列及制法和用途
WO2003074556A1 (fr) Marqueur tumoral et ses applications
CN101168562A (zh) Cbp c端蛋白、其单克隆抗体及其制备与应用