CA2612394C - Her-2 peptides - Google Patents

Her-2 peptides Download PDF

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Publication number
CA2612394C
CA2612394C CA2612394A CA2612394A CA2612394C CA 2612394 C CA2612394 C CA 2612394C CA 2612394 A CA2612394 A CA 2612394A CA 2612394 A CA2612394 A CA 2612394A CA 2612394 C CA2612394 C CA 2612394C
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CA
Canada
Prior art keywords
seq
epitope
sequence
epitopes
peptide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CA2612394A
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English (en)
French (fr)
Other versions
CA2612394A1 (en
Inventor
Pravin T. P. Kaumaya
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ohio State University Research Foundation
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Ohio State University Research Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ohio State University Research Foundation filed Critical Ohio State University Research Foundation
Publication of CA2612394A1 publication Critical patent/CA2612394A1/en
Application granted granted Critical
Publication of CA2612394C publication Critical patent/CA2612394C/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/0005Vertebrate antigens
    • A61K39/0011Cancer antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/71Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/82Translation products from oncogenes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Zoology (AREA)
  • Oncology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Toxicology (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
CA2612394A 2005-06-15 2006-06-15 Her-2 peptides Active CA2612394C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US69057405P 2005-06-15 2005-06-15
US60/690,574 2005-06-15
PCT/US2006/023672 WO2006138675A2 (en) 2005-06-15 2006-06-15 Her-2 peptides

Publications (2)

Publication Number Publication Date
CA2612394A1 CA2612394A1 (en) 2006-12-28
CA2612394C true CA2612394C (en) 2017-02-21

Family

ID=37571268

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2612394A Active CA2612394C (en) 2005-06-15 2006-06-15 Her-2 peptides

Country Status (7)

Country Link
US (3) US7691396B2 (enExample)
EP (1) EP1912680B1 (enExample)
JP (2) JP5222134B2 (enExample)
AU (1) AU2006261342B2 (enExample)
CA (1) CA2612394C (enExample)
ES (1) ES2531483T3 (enExample)
WO (1) WO2006138675A2 (enExample)

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WO2006138675A2 (en) 2005-06-15 2006-12-28 The Ohio State University Research Foundation Her-2 peptides
US8945573B2 (en) * 2005-09-08 2015-02-03 The Henry M. Jackson Foundation For The Advancement Of Military Medicine, Inc. Targeted identification of immunogenic peptides
WO2008097229A1 (en) * 2007-02-09 2008-08-14 The Government Of The Usa As Represented By The Secretary Of The Dept. Of Health And Human Services Method for spectroscopic quantitation of her-2 in biological samples
JP5269186B2 (ja) * 2008-04-22 2013-08-21 ロックウッド・リチウム・インコーポレイテッド 高純度水酸化リチウムと塩酸とを製造する方法
US20100234283A1 (en) 2009-02-04 2010-09-16 The Ohio State University Research Foundation Immunogenic epitopes, peptidomimetics, and anti-peptide antibodies, and methods of their use
US9125848B2 (en) 2010-06-10 2015-09-08 The Cleveland Clinic Foundation Alpha lactalbumin immunization methods
RU2607033C2 (ru) * 2010-09-28 2017-01-10 Ноно Инк. Пептиды nd2 и способы лечения неврологического заболевания
RU2645085C2 (ru) 2012-04-16 2018-02-15 Дзе Кливленд Клиник Фаундейшн Мультивалентная вакцина против рака молочной железы
WO2014131019A2 (en) 2013-02-25 2014-08-28 Ohio State Innovation Foundation Her-1, her-3 and igf-1r compositions and uses thereof
CN105017425B (zh) * 2014-04-30 2018-02-16 京天成生物技术(北京)有限公司 抗her2中和活性单克隆抗体及其应用
WO2017078761A2 (en) * 2015-11-06 2017-05-11 Evorx Technologies, Inc. Her-2-specific cyclized supr peptides
WO2018145020A1 (en) 2017-02-03 2018-08-09 The Medical College Of Wisconsin, Inc. Kras peptide vaccine compositions and method of use
CA3058393A1 (en) * 2017-03-28 2018-10-04 Ohio State Innovation Foundation Human pd1 peptide vaccines and uses thereof
US20200179500A1 (en) * 2018-12-05 2020-06-11 Wayne State University Methods and immunogenic compositions relating to her2 with selective sequence modifications
US20220169747A1 (en) * 2019-03-22 2022-06-02 Olivia Newton-John Cancer Research Institute Anti-her2 binding molecules
AU2020350666A1 (en) * 2019-09-17 2022-03-31 Ohio State Innovation Foundation Human anti-PD-L1 peptide vaccines and methods of their use
CN119136838A (zh) 2022-02-28 2024-12-13 特瑞德姆生物科技有限责任两合公司 由至少一种β-葡聚糖或甘露聚糖组成或包含至少一种β-葡聚糖或甘露聚糖的偶联物
CN119019569B (zh) * 2024-08-19 2025-10-24 中国人民解放军陆军军医大学 一种可定向增强胸腺新生t细胞杀伤乳腺癌的多肽及其应用

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US5801005A (en) * 1993-03-17 1998-09-01 University Of Washington Immune reactivity to HER-2/neu protein for diagnosis of malignancies in which the HER-2/neu oncogene is associated
US5869445A (en) * 1993-03-17 1999-02-09 University Of Washington Methods for eliciting or enhancing reactivity to HER-2/neu protein
GB9326253D0 (en) 1993-12-23 1994-02-23 Smithkline Beecham Biolog Vaccines
JP3468773B2 (ja) 1994-07-15 2003-11-17 ザ ユニバーシティ オブ アイオワ リサーチ ファウンデーション 免疫調節オリゴヌクレオチド
UA56132C2 (uk) 1995-04-25 2003-05-15 Смітклайн Бічем Байолоджікалс С.А. Композиція вакцини (варіанти), спосіб стабілізації qs21 відносно гідролізу (варіанти), спосіб приготування композиції вакцини
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JP2008500015A (ja) * 2003-10-29 2008-01-10 ラモト アット テル アヴィヴ ユニヴァーシティ リミテッド 血管形成ペプチドおよびその使用
WO2005076972A2 (en) * 2004-02-05 2005-08-25 The Ohio State University Research Foundation Chimeric vegf peptides
SE527089C2 (sv) 2004-10-19 2005-12-20 Mia Kumm Anordning och system för ventilation av tunnel vid brand
BRPI0519172A2 (pt) * 2004-12-20 2008-12-30 Ajimoto Kk proteÍna mutante, polinucleotÍdeo, microorganismo transformado, e, mÉtodos de produzir uma proteÍna mutante, um peptÍdeo, e alfa-l-aspartil-l-fenilalanina-beta-Éster, e de projetar e produzir uma proteÍna mutante
WO2006138675A2 (en) 2005-06-15 2006-12-28 The Ohio State University Research Foundation Her-2 peptides
US20100234283A1 (en) * 2009-02-04 2010-09-16 The Ohio State University Research Foundation Immunogenic epitopes, peptidomimetics, and anti-peptide antibodies, and methods of their use
JP5510272B2 (ja) 2010-06-21 2014-06-04 株式会社リコー 画像形成装置

Also Published As

Publication number Publication date
WO2006138675A2 (en) 2006-12-28
US7691396B2 (en) 2010-04-06
EP1912680A2 (en) 2008-04-23
AU2006261342A1 (en) 2006-12-28
JP5542865B2 (ja) 2014-07-09
ES2531483T3 (es) 2015-03-16
EP1912680A4 (en) 2010-09-22
US20070060516A1 (en) 2007-03-15
CA2612394A1 (en) 2006-12-28
US9452204B2 (en) 2016-09-27
AU2006261342B2 (en) 2012-02-02
JP2012136555A (ja) 2012-07-19
US20140010831A1 (en) 2014-01-09
JP5222134B2 (ja) 2013-06-26
US8470333B2 (en) 2013-06-25
EP1912680B1 (en) 2014-11-26
JP2009500298A (ja) 2009-01-08
US20110086055A1 (en) 2011-04-14
WO2006138675A9 (en) 2010-01-28

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