ES2525441T3 - Sulfonamidas nematocidas - Google Patents

Sulfonamidas nematocidas Download PDF

Info

Publication number
ES2525441T3
ES2525441T3 ES11770306.6T ES11770306T ES2525441T3 ES 2525441 T3 ES2525441 T3 ES 2525441T3 ES 11770306 T ES11770306 T ES 11770306T ES 2525441 T3 ES2525441 T3 ES 2525441T3
Authority
ES
Spain
Prior art keywords
2nr11r12
nr11r12
alkyl
nr5r6
alkynyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES11770306.6T
Other languages
English (en)
Inventor
George P. Lahm
Thomas Francis Pahutski Jr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
EIDP Inc
Original Assignee
EI Du Pont de Nemours and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by EI Du Pont de Nemours and Co filed Critical EI Du Pont de Nemours and Co
Application granted granted Critical
Publication of ES2525441T3 publication Critical patent/ES2525441T3/es
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/90—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having two or more relevant hetero rings, condensed among themselves or with a common carbocyclic ring system
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/02—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms
    • A01N43/24—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with two or more hetero atoms
    • A01N43/26—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with two or more hetero atoms five-membered rings
    • A01N43/28—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with two or more hetero atoms five-membered rings with two hetero atoms in positions 1,3
    • A01N43/30—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with two or more hetero atoms five-membered rings with two hetero atoms in positions 1,3 with two oxygen atoms in positions 1,3, condensed with a carbocyclic ring
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/48—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
    • A01N43/54—1,3-Diazines; Hydrogenated 1,3-diazines
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/48—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
    • A01N43/60—1,4-Diazines; Hydrogenated 1,4-diazines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N2300/00—Combinations or mixtures of active ingredients covered by classes A01N27/00 - A01N65/48 with other active or formulation relevant ingredients, e.g. specific carrier materials or surfactants, covered by classes A01N25/00 - A01N65/48

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Plant Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Dentistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Pest Control & Pesticides (AREA)
  • Agronomy & Crop Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

Un compuesto seleccionado de la Formula 1, un N-oxido o una sal de estos, caracterizado porque Z es O o S; A1, A2, A3 y A4 son independientemente N o CR1, siempre que solo uno de A1, A2, A3 y A4 sea N; cada R1 es independientemente H, halogeno, ciano, nitro, OR4, NR5R6, alquilo de C1 a C6, haloalquilo de C1 a C6, alquenilo de C2 a C6, haloalquenilo de C2 a C6, alquinilo de C2 a C6, haloalquinilo de C2 a C6, cicloalquilo de C3 a C7, C(X)R7, C(O)OR8, C(O)NR11R12, S(O)mR9 o S(O)2NR11R12; o fenilo, naftalenilo o un anillo heteroaromatico de 5 o 6 miembros, cada uno opcionalmente sustituido con 1 a 5 sustituyentes seleccionados independientemente del grupo que consiste en halogeno, ciano, nitro, OR4, NR5R6, alquilo de C1 a C4, alquenilo de C2 a C4, alquinilo de C2 a C4, haloalquilo de C1 a C4, haloalquenilo de C2 a C4, C(X)R7, C(O)OR8, C(O)NR11R12, S(O)mR9 y S(O)2NR11R12; R2 es H, halogeno, ciano, nitro, OR4, NR5R6, alquilo de C1 a C6, haloalquilo de C1 a C6, alquenilo de C2 a C6, haloalquenilo de C2 a C6, alquinilo de C2 a C6, haloalquinilo de C2 a C6, cicloalquilo de C3 a C7, C(X)R7, C(O)OR8, C(O)NR11R12, S(O)mR9 o S(O)2NR11R12; o fenilo, naftalenilo o un anillo heteroaromatico de 5 o 6 miembros, cada uno opcionalmente sustituido con 1 a 5 sustituyentes seleccionados independientemente del grupo que consiste en halogeno, ciano, nitro, OR4, NR5R6, alquilo de C1 a C4, alquenilo de C2 a C4, alquinilo de C2 a C4, haloalquilo de C1 a C4, haloalquenilo de C2 a C4, C(X)R7, C(O)OR8, C(O)NR11R12, S(O)mR9 y S(O)2NR11R12; R3 es H, C(X)R7, C(O)OR8, C(O)NR11R12, S(O)mR9 o S(O)2NR11R12; o alquilo de C1 a C6, alquenilo de C2 a C6, alquinilo de C2 a C6, cicloalquilo de C3 a C7, cicloalquilalquilo de C4 a C8 o cicloalquenilo de C5 a C7, cada uno opcionalmente sustituido con 1 a 4 sustituyentes seleccionados independientemente del grupo que consiste en halogeno, ciano, nitro, OR4, NR5R6, C(X)R7, C(O)OR8, C(O)NR11R12, S(O)mR9 y S(O)2NR11R12; o alquilo de C1 a C6 sustituido con 1 o 2 sustituyentes seleccionados independientemente del grupo que consiste en fenilo o un anillo heteroaromatico de 5 o 6 miembros, cada uno opcionalmente sustituido con 1 a 5 sustituyentes seleccionados independientemente del grupo que consiste en halogeno, ciano, nitro, OR4, NR5R6, alquilo de C1 a C4, alquenilo de C2 a C4, alquinilo de C2 a C4, haloalquilo de C1 a C4, haloalquenilo de C2 a C4, alcoxialquilo de C2 a C6, C(X)R7, C(O)OR8, C(O)NR11R12, S(O)mR9 y S(O)2NR11R12; Q es fenilo, naftalenilo, un anillo heteroaromatico de 5 o 6 miembros o un sistema anular biciclico aromatico de 8 a 10 miembros, cada uno opcionalmente sustituido con 1 a 5 sustituyentes seleccionados independientemente del grupo que consiste en halogeno, ciano, nitro, OR4, NR5R6, alquilo de C1 a C6, haloalquilo de C1 a C6, alquenilo de C2 a C6, haloalquenilo de C2 a C6, alquinilo de C2 a C6, haloalquinilo de C2 a C6, C(X)R7, C(O)OR8, C(X)NR11R12, S(O)mR9, S(O)2NR11R12, OC(O)R7, OC(O)OR8, OC(O)NR11R12, OS(O)2R9, OS(O)2NR11R12, N(R10)C(O)R7, N(R10)C(O)NR11R12, N(R10)S(O)2R9, N(R10)S(O)2NR11R12 y R14; cada X es independientemente O o S.

Description

imagen1
imagen2
imagen3
imagen4
imagen5
imagen6
imagen7
imagen8

Claims (1)

  1. imagen1
    imagen2
    imagen3
    imagen4
ES11770306.6T 2010-10-18 2011-10-05 Sulfonamidas nematocidas Active ES2525441T3 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US39408010P 2010-10-18 2010-10-18
US394080P 2010-10-18
PCT/US2011/054868 WO2012054233A1 (en) 2010-10-18 2011-10-05 Nematocidal sulfonamides

Publications (1)

Publication Number Publication Date
ES2525441T3 true ES2525441T3 (es) 2014-12-23

Family

ID=44801224

Family Applications (1)

Application Number Title Priority Date Filing Date
ES11770306.6T Active ES2525441T3 (es) 2010-10-18 2011-10-05 Sulfonamidas nematocidas

Country Status (10)

Country Link
US (1) US9023850B2 (es)
EP (1) EP2629614B1 (es)
JP (1) JP5815720B2 (es)
KR (1) KR101941300B1 (es)
CN (1) CN103188934B (es)
AU (1) AU2011318398B2 (es)
BR (1) BR112013007604B1 (es)
ES (1) ES2525441T3 (es)
MX (1) MX343596B (es)
WO (1) WO2012054233A1 (es)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105555136A (zh) * 2013-07-17 2016-05-04 拜耳作物科学股份公司 具有杀线虫性能的杂环磺酰氨基(硫代)羰基衍生物
MA38798B1 (fr) 2013-07-23 2017-10-31 Bayer Cropscience Ag Imidazothia(dia)zole sulfonamides utilisés en tant que nématicides
US9493442B2 (en) 2014-02-13 2016-11-15 Incyte Corporation Cyclopropylamines as LSD1 inhibitors
LT3105226T (lt) 2014-02-13 2019-11-11 Incyte Corp Ciklopropilaminai, kaip lsd1 inhibitoriai
PL3105218T3 (pl) 2014-02-13 2020-03-31 Incyte Corporation Cyklopropyloaminy jako inhibitory lsd1
WO2015123437A1 (en) 2014-02-13 2015-08-20 Incyte Corporation Cyclopropylamines as lsd1 inhibitors
ES2667727T3 (es) * 2014-05-08 2018-05-14 Bayer Cropscience Aktiengesellschaft Pirazolopiridina sulfonamidas como nematicidas
TW201613925A (en) 2014-07-10 2016-04-16 Incyte Corp Imidazopyrazines as LSD1 inhibitors
WO2016007722A1 (en) 2014-07-10 2016-01-14 Incyte Corporation Triazolopyridines and triazolopyrazines as lsd1 inhibitors
WO2016007731A1 (en) 2014-07-10 2016-01-14 Incyte Corporation Imidazopyridines and imidazopyrazines as lsd1 inhibitors
WO2016007727A1 (en) 2014-07-10 2016-01-14 Incyte Corporation Triazolopyridines and triazolopyrazines as lsd1 inhibitors
EP3277689B1 (en) 2015-04-03 2019-09-04 Incyte Corporation Heterocyclic compounds as lsd1 inhibitors
CN105061433A (zh) * 2015-07-24 2015-11-18 河南紫罗兰科技有限公司 一类5-溴-咪唑并[1,2-a]嘧啶-3-羧酸酯及其相应酸的合成方法
SG10202001219UA (en) 2015-08-12 2020-03-30 Incyte Corp Salts of an lsd1 inhibitor
KR20180125960A (ko) 2016-03-15 2018-11-26 바이엘 크롭사이언스 악티엔게젤샤프트 동물 해충을 방제하기 위한 치환된 술포닐 아미드
PE20190377A1 (es) 2016-04-22 2019-03-08 Incyte Corp Formulaciones de un inhibidor de lsd 1
CN105901003A (zh) * 2016-04-25 2016-08-31 广东中迅农科股份有限公司 含有三氟咪啶酰胺的农药组合物
TW201822637A (zh) 2016-11-07 2018-07-01 德商拜耳廠股份有限公司 用於控制動物害蟲的經取代磺醯胺類
WO2019109132A1 (en) * 2017-12-05 2019-06-13 Bionomics Limited Isoxazolyl compounds as receptor modulating compounds and methods and uses thereof
WO2020047198A1 (en) 2018-08-31 2020-03-05 Incyte Corporation Salts of an lsd1 inhibitor and processes for preparing the same
BR112021006329B1 (pt) 2018-10-05 2023-04-18 E. I. Du Pont De Nemours And Company Método de preparação de certas sulfonamidas nematicidas
WO2020191091A1 (en) 2019-03-19 2020-09-24 Boehringer Ingelheim Animal Health USA Inc. Anthelmintic aza-benzothiophene and aza-benzofuran compounds
JP2023501978A (ja) 2019-11-07 2023-01-20 バイエル・アクチエンゲゼルシヤフト 動物害虫駆除用の置換スルホニルアミド
WO2021094210A1 (en) 2019-11-12 2021-05-20 Bayer Aktiengesellschaft Substituted pyrazine carboxamide derivatives as prostaglandin ep3 receptor antagonists
US11718622B2 (en) 2020-03-16 2023-08-08 Exelixis Inc. Heterocyclic adenosine receptor antagonists
BR112022024156A2 (pt) 2020-05-29 2023-02-14 Boehringer Ingelheim Animal Health Usa Inc Compostos heterocílicos antelmínticos
AU2022377394A1 (en) 2021-11-01 2024-06-13 Boehringer Ingelheim Vetmedica Gmbh Anthelmintic pyrrolopyridazine compounds
WO2023144711A1 (en) 2022-01-27 2023-08-03 Pi Industries Ltd. 1,2,3-triazole carbonyl sulfonylamide compounds and use thereof
WO2024102600A1 (en) 2022-11-10 2024-05-16 Corteva Agriscience Llc Preparation of imidazopyridine-2-carboxylic acids

Family Cites Families (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2891855A (en) 1954-08-16 1959-06-23 Geigy Ag J R Compositions and methods for influencing the growth of plants
US3235361A (en) 1962-10-29 1966-02-15 Du Pont Method for the control of undesirable vegetation
US3060084A (en) 1961-06-09 1962-10-23 Du Pont Improved homogeneous, readily dispersed, pesticidal concentrate
US3299566A (en) 1964-06-01 1967-01-24 Olin Mathieson Water soluble film containing agricultural chemicals
US3309192A (en) 1964-12-02 1967-03-14 Du Pont Method of controlling seedling weed grasses
US4144050A (en) 1969-02-05 1979-03-13 Hoechst Aktiengesellschaft Micro granules for pesticides and process for their manufacture
US3920442A (en) 1972-09-18 1975-11-18 Du Pont Water-dispersible pesticide aggregates
US4179277A (en) * 1976-03-12 1979-12-18 Bayer Aktiengesellschaft 4,5-Dichloroimidazole-2-carboxylic acid derivatives
US4172714A (en) 1976-12-20 1979-10-30 E. I. Du Pont De Nemours And Company Dry compactible, swellable herbicidal compositions and pellets produced therefrom
GB2095558B (en) 1981-03-30 1984-10-24 Avon Packers Ltd Formulation of agricultural chemicals
DE3246493A1 (de) 1982-12-16 1984-06-20 Bayer Ag, 5090 Leverkusen Verfahren zur herstellung von wasserdispergierbaren granulaten
CA1273336A (en) 1986-04-25 1990-08-28 Chi-Ping Tseng Herbicidal heterocyclic carbonyl sulfonamides
JPS6322077A (ja) * 1986-04-25 1988-01-29 イ−・アイ・デユポン・デ・ニモアス・アンド・カンパニ− 複素環式アセチルスルホンアミド類
US4731446A (en) * 1987-05-01 1988-03-15 The Dow Chemical Company Imidazo[1,2-a]pyrimidine sulfonic acids and acid halides
US5180587A (en) 1988-06-28 1993-01-19 E. I. Du Pont De Nemours And Company Tablet formulations of pesticides
ES2166919T3 (es) 1989-08-30 2002-05-01 Kynoch Agrochemicals Proprieta Preparacion de un dispositivo dosificador.
CA2083185A1 (en) 1990-03-12 1991-09-13 William Lawrence Geigle Water-dispersible or water-soluble pesticide granules from heat-activated binders
DE69122201T2 (de) 1990-10-11 1997-02-06 Sumitomo Chemical Co Pestizide Zusammensetzung
DE19742951A1 (de) * 1997-09-29 1999-04-15 Hoechst Schering Agrevo Gmbh Acylsulfamoylbenzoesäureamide, diese enthaltende nutzpflanzenschützende Mittel und Verfahren zu ihrer Herstellung
JP2001294581A (ja) * 2000-04-12 2001-10-23 Nippon Bayer Agrochem Co Ltd イソチアゾール誘導体
MXPA03003923A (es) * 2000-11-03 2004-05-05 Dow Agrosciences Llc Compuestos de n-([1,2,4]triazoloazinil)tiofensulfonamida como herbicidas.
TW200724033A (en) 2001-09-21 2007-07-01 Du Pont Anthranilamide arthropodicide treatment
CN101316853B (zh) * 2005-08-04 2014-09-24 西特里斯药业公司 作为sirtuin调节剂的苯并噻唑和噻唑并吡啶
CN101415698A (zh) * 2006-04-05 2009-04-22 拜尔农科股份有限公司 杀真菌剂n-环丙基-磺酰胺衍生物
TW201029575A (en) * 2009-01-29 2010-08-16 Ishihara Sangyo Kaisha Triazolopyrimidine derivative or its salt, process for producing the same and pesticide containing the same
TWI482771B (zh) * 2009-05-04 2015-05-01 Du Pont 磺醯胺殺線蟲劑
US8618179B2 (en) * 2010-01-18 2013-12-31 Basf Se Composition comprising a pesticide and an alkoxylate of 2-propylheptylamine

Also Published As

Publication number Publication date
CN103188934A (zh) 2013-07-03
EP2629614A1 (en) 2013-08-28
EP2629614B1 (en) 2014-09-17
BR112013007604A8 (pt) 2018-01-30
BR112013007604A2 (pt) 2016-09-20
JP5815720B2 (ja) 2015-11-17
US9023850B2 (en) 2015-05-05
CN103188934B (zh) 2015-08-26
WO2012054233A1 (en) 2012-04-26
MX2013004242A (es) 2013-05-30
AU2011318398B2 (en) 2015-09-10
BR112013007604B1 (pt) 2018-06-05
JP2013541558A (ja) 2013-11-14
US20130190172A1 (en) 2013-07-25
KR20130132440A (ko) 2013-12-04
AU2011318398A1 (en) 2013-03-21
KR101941300B1 (ko) 2019-01-22
MX343596B (es) 2016-11-11

Similar Documents

Publication Publication Date Title
ES2525441T3 (es) Sulfonamidas nematocidas
CY1122325T1 (el) Ενωσεις ρυθμισης fxr (nr1h4)
AR114164A1 (es) Piridopirimidinonas sustituidas con bencilamino y derivados como inhibidores de sos1
CY1120899T1 (el) Παραγωγα 1,2,4-οξαδιαζολιου ως ανοσοτροποποιητες
PE20181269A1 (es) Agonistas del receptor de apelina y metodos de uso
AR098912A1 (es) Inhibidores de syk
AR100691A1 (es) Esteroides neuroactivos, composiciones, y usos de los mismos
AR103561A1 (es) Fenilpiridinas herbicidas
AR068764A1 (es) N-piperazin amidas y su uso en medicamentos para el tratamiento de enfermedades mediadas por la inhibicion de faah.
CL2017003240A1 (es) Anticuerpos anti-rnf43 novedosos y métodos para su uso
EA201001331A1 (ru) ГЕТЕРОЦИКЛИЧЕСКИЕ СОЕДИНЕНИЯ И СОДЕРЖАЩИЕ ИХ КОМПОЗИЦИИ В КАЧЕСТВЕ ИНГИБИТОРОВ КИНАЗ c-kit И PDGFR
PE20150399A1 (es) Nuevos derivados de pirrol, su procedimiento de preparacion y las composiciones farmaceuticas que los contienen
AR100251A1 (es) Inhibidores de la dematilasa-1 especifica de lisina
CY1122182T1 (el) Ανοσοκατασταλτικες φαρμακοτεχνικες μορφες
CL2017000271A1 (es) Derivados de pirimidina sustituidos con heterociclilo opcionalmente condensados útiles para el tratamiento de enfermedades inflamatorias, metabólicas, oncológicas y autoinmunitarias
EA201600128A1 (ru) СОЛИ ПРОИЗВОДНЫХ 2-АМИНО-1-ГИДРОКСИЭТИЛ-8-ГИДРОКСИХИНОЛИН-2(1Н)-ОНА, ОБЛАДАЮЩИЕ АНТАГОНИСТИЧЕСКОЙ АКТИВНОСТЬЮ ПО ОТНОШЕНИЮ К МУСКАРИНОВОМУ РЕЦЕПТОРУ И АГОНИСТИЧЕСКОЙ АКТИВНОСТЬЮ ПО ОТНОШЕНИЮ К β2 АДРЕНЕРГИЧЕСКОМУ РЕЦЕПТОРУ
AR097543A1 (es) COMPUESTOS BASADOS EN IMIDAZO[1,2-b]PIRIDAZINA, COMPOSICIONES QUE LOS COMPRENDEN Y SUS MÉTODOS DE USO
BR112014009006B8 (pt) Compostos heterocíclicos e métodos de uso dos mesmos
AR097866A1 (es) Derivados de 4-azaindol
ECSP16074478A (es) Compuestos novedosos
WO2014135974A3 (en) Systems and methods for developing and managing oncology treatment plans
ECSP17010481A (es) Novedosas pirimidinas 2,5-sustituidas
AR072803A1 (es) Tetrahidrocinolinas como inhibidores de la 11- beta -hsd1 para la diabetes
PE20211246A1 (es) Compuestos biciclicos para su uso como inhibidores de rip1 quinasa
EA201790939A1 (ru) ТРИАЗОЛО[4,5-d]ПИРИМИДИНЫ В КАЧЕСТВЕ АГОНИСТОВ КАННАБИНОИДНЫХ РЕЦЕПТОРОВ ТИПА 2