ES2519190T3 - Composiciones de antibiótico para el tratamiento ocular - Google Patents

Composiciones de antibiótico para el tratamiento ocular Download PDF

Info

Publication number
ES2519190T3
ES2519190T3 ES10178657.2T ES10178657T ES2519190T3 ES 2519190 T3 ES2519190 T3 ES 2519190T3 ES 10178657 T ES10178657 T ES 10178657T ES 2519190 T3 ES2519190 T3 ES 2519190T3
Authority
ES
Spain
Prior art keywords
composition
ophthalmic
influenzae
compositions
use according
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES10178657.2T
Other languages
English (en)
Spanish (es)
Inventor
Gerald Cagle
Robert L. Abshire
David W. Stroman
John M. Yanni
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Alcon Pharmaceuticals Ltd
Original Assignee
Alcon Pharmaceuticals Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26799441&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2519190(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Alcon Pharmaceuticals Ltd filed Critical Alcon Pharmaceuticals Ltd
Application granted granted Critical
Publication of ES2519190T3 publication Critical patent/ES2519190T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5365—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines ortho- or peri-condensed with heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/5383—1,4-Oxazines, e.g. morpholine ortho- or peri-condensed with heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0043—Nose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0046—Ear
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/02—Nasal agents, e.g. decongestants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/16—Otologicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/02—Local antiseptics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Pulmonology (AREA)
  • Communicable Diseases (AREA)
  • Otolaryngology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
ES10178657.2T 1998-09-30 1999-09-29 Composiciones de antibiótico para el tratamiento ocular Expired - Lifetime ES2519190T3 (es)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US10250698P 1998-09-30 1998-09-30
US10250498P 1998-09-30 1998-09-30
US102504P 1998-09-30
US102506P 1998-09-30

Publications (1)

Publication Number Publication Date
ES2519190T3 true ES2519190T3 (es) 2014-11-06

Family

ID=26799441

Family Applications (4)

Application Number Title Priority Date Filing Date
ES10176412.4T Expired - Lifetime ES2526521T3 (es) 1998-09-30 1999-09-29 Composiciones de antibiótico para el tratamiento del oído
ES99956504T Expired - Lifetime ES2207307T3 (es) 1998-09-30 1999-09-29 Composiciones antibioticas para el tratamiento de los ojos.
ES10178657.2T Expired - Lifetime ES2519190T3 (es) 1998-09-30 1999-09-29 Composiciones de antibiótico para el tratamiento ocular
ES14176366.4T Expired - Lifetime ES2602956T3 (es) 1998-09-30 1999-09-29 Composiciones de antibiótico para tratamiento de conjuntivitis

Family Applications Before (2)

Application Number Title Priority Date Filing Date
ES10176412.4T Expired - Lifetime ES2526521T3 (es) 1998-09-30 1999-09-29 Composiciones de antibiótico para el tratamiento del oído
ES99956504T Expired - Lifetime ES2207307T3 (es) 1998-09-30 1999-09-29 Composiciones antibioticas para el tratamiento de los ojos.

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES14176366.4T Expired - Lifetime ES2602956T3 (es) 1998-09-30 1999-09-29 Composiciones de antibiótico para tratamiento de conjuntivitis

Country Status (18)

Country Link
EP (5) EP1384478B1 (forum.php)
JP (5) JP2002525317A (forum.php)
KR (1) KR101463243B1 (forum.php)
CN (2) CN100374114C (forum.php)
AR (2) AR020661A1 (forum.php)
AT (2) ATE254458T1 (forum.php)
AU (1) AU762827B2 (forum.php)
BR (1) BRPI9914151B1 (forum.php)
CA (3) CA2774207A1 (forum.php)
CY (3) CY1111404T1 (forum.php)
DE (2) DE69912972T2 (forum.php)
DK (5) DK2269602T3 (forum.php)
ES (4) ES2526521T3 (forum.php)
HK (1) HK1038691B (forum.php)
PT (5) PT1384478E (forum.php)
TR (2) TR200100883T2 (forum.php)
TW (1) TWI222361B (forum.php)
WO (1) WO2000018386A2 (forum.php)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
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US6509327B1 (en) * 1998-09-30 2003-01-21 Alcon Manufacturing, Ltd. Compositions and methods for treating otic, ophthalmic and nasal infections
US6716830B2 (en) 1998-09-30 2004-04-06 Alcon, Inc. Ophthalmic antibiotic compositions containing moxifloxacin
US6395746B1 (en) 1998-09-30 2002-05-28 Alcon Manufacturing, Ltd. Methods of treating ophthalmic, otic and nasal infections and attendant inflammation
AR020661A1 (es) 1998-09-30 2002-05-22 Alcon Lab Inc Una composicion farmaceutica topica oftalmica, otica o nasal y el uso de la misma para la manufactura de un medicamento
DE19937116A1 (de) * 1999-08-06 2001-02-08 Bayer Ag Moxifloxacin Kochsalzformulierung
DE19937115A1 (de) * 1999-08-06 2001-02-08 Bayer Ag Wäßrige Arzneimittelformulierung von Moxifloxacin oder Salzen davon
DK1214056T3 (da) 1999-09-24 2004-02-09 Alcon Inc Topiske suspensionsformuleringer indeholdende ciprofloxacin og dexamethason
DE19962470A1 (de) 1999-12-22 2001-07-12 Schulz Hans Herrmann Verwendung von Chemotherapeutika
AU2001261748A1 (en) * 2000-05-19 2001-12-03 Alcon Laboratories Inc. Antibiotic compositions for treatment of the eye, ear and nose
AU2001276928A1 (en) 2000-07-26 2002-02-05 Alcon Universal Ltd. Improved process for manufacturing compositions containing ciprofloxacin and hydrocortisone
JPWO2002040028A1 (ja) * 2000-11-16 2004-03-18 わかもと製薬株式会社 抗菌ゲル化点眼剤
US7025958B2 (en) 2000-12-20 2006-04-11 Alcon, Inc. Use of amidoamines to treat or prevent acanthamoeba and fungal infections
WO2002049627A2 (en) * 2000-12-20 2002-06-27 Alcon, Inc. Antifungal compositions containing an antibiotic and one or more amidoamines
KR20040035760A (ko) 2001-09-21 2004-04-29 알콘, 인코퍼레이티드 중이염 치료 방법
US7220431B2 (en) 2002-11-27 2007-05-22 Regents Of The University Of Minnesota Methods and compositions for applying pharmacologic agents to the ear
DK1666477T3 (da) 2003-09-10 2013-07-29 Kyorin Seiyaku Kk 7-(4-trisubstitueret 3-cyclopropylaminomethyl-1- pyrrolidinyl)-quinoloncarboxylsyre-derivat
WO2006015545A1 (fr) * 2004-08-11 2006-02-16 Shenzhen Tys R & D Co., Ltd. Capsule de gelatine de moxifloxacin et procede pour sa preparation
JP2008512383A (ja) * 2004-09-03 2008-04-24 ピードモント ファーマシューティカルズ エルエルシー 中耳炎の経膜治療方法および予防方法
DE102005055385A1 (de) * 2004-12-09 2006-06-14 Bayer Healthcare Ag Arzneimittel zur hygienischen Applikation im Ohr
JP2008523060A (ja) * 2004-12-10 2008-07-03 アルコン，インコーポレイティド 耳感染の処置のための組成物
CN101317847B (zh) * 2007-06-06 2010-10-13 深圳市瑞谷医药技术有限公司 一种眼用或耳鼻用药物组合物及其用途
TWI495469B (zh) 2008-06-09 2015-08-11 Alcon Res Ltd 含有氟喹諾酮抗生素藥物之經改良藥學組成物
MX2012000136A (es) * 2009-07-02 2012-02-08 Alcon Res Ltd Composiciones que comprenden finafloxacina y metodos para tratar infecciones oftalmicas, oticas, o nasales.
KR20180027611A (ko) * 2010-01-07 2018-03-14 리전츠 오브 더 유니버스티 오브 미네소타 목시플록사신을 귀에 도포하기 위한 방법 및 조성물
BR112014012885A2 (pt) 2011-12-06 2017-06-13 Alcon Res Ltd composição de gel celulósica com estabilidade de viscosidade aperfeiçoada
RU2472507C1 (ru) * 2012-02-01 2013-01-20 Закрытое акционерное общество "Брынцалов-А" Водный состав на основе моксифлоксацина для парентерального введения
US9504691B2 (en) * 2012-12-06 2016-11-29 Alcon Research, Ltd. Finafloxacin suspension compositions
US20150164882A1 (en) 2013-07-22 2015-06-18 Imprimis Pharmaceuticals, Inc. Pharmaceutical compositions for intraocular administration and methods for fabricating thereof
US20160279055A1 (en) 2013-07-22 2016-09-29 Imprimis Pharmaceuticals, Inc. Pharmaceutical ophthalmic compositions for intraocular administration and methods for fabricating thereof
CN104224802B (zh) * 2014-09-19 2017-12-12 南京优科生物医药研究有限公司 一种盐酸莫西沙星滴耳剂及其制备方法
RU2595837C2 (ru) * 2014-09-29 2016-08-27 Открытое Акционерное Общество "Татхимфармпрепараты" Состав и способ получения глазных капель
WO2017073708A1 (ja) * 2015-10-29 2017-05-04 テイカ製薬株式会社 外用剤
US20210386759A1 (en) * 2020-06-10 2021-12-16 Ocular Science, Inc. Compositions and methods for post-operative ocular care
US12042500B2 (en) * 2018-04-03 2024-07-23 Hyderabad Eye Research Foundation Mucoadhesive drug delivery system for ocular administration of fluoroquinolone antibiotics
IT201900005280A1 (it) * 2019-04-05 2020-10-05 Ntc S R L Composizione otologica
CN116270662A (zh) * 2021-12-03 2023-06-23 苏州欧康维视生物科技有限公司 盐酸莫西沙星地塞米松磷酸钠滴眼液
KR102656260B1 (ko) 2022-10-14 2024-04-09 주식회사태준제약 목시플록사신을 포함하는 안과용 조성물

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JPH0892241A (ja) * 1994-09-22 1996-04-09 Ss Pharmaceut Co Ltd ５−ヒドラジノキノロンカルボン酸誘導体及びこれを有効成分とする抗菌剤
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WO1996039146A1 (en) * 1995-06-06 1996-12-12 Bayer Corporation Non-irritation, non-sensitizing, non-ototoxic otic antibacterial compositions
JP3290914B2 (ja) * 1997-03-17 2002-06-10 参天製薬株式会社 眼組織におけるキノロン系抗菌剤の定量装置
CN1895233A (zh) * 1997-09-25 2007-01-17 拜尔公司 控释活性化合物的药物制剂
TR200100846T2 (tr) 1998-09-23 2002-03-21 Unilever N.V. AĞìz bakìmìna iliçkin bileçimler
AR020661A1 (es) 1998-09-30 2002-05-22 Alcon Lab Inc Una composicion farmaceutica topica oftalmica, otica o nasal y el uso de la misma para la manufactura de un medicamento
US20020001617A1 (en) * 2000-05-26 2002-01-03 Chang-Hyun Lee Rapidly disintegrating tablet and process for the manufacture thereof

Also Published As

Publication number Publication date
JP2012067141A (ja) 2012-04-05
JP2014144982A (ja) 2014-08-14
DK2301541T3 (da) 2014-09-01
EP2301541B1 (en) 2014-08-20
CA2659064A1 (en) 2000-04-06
WO2000018386A2 (en) 2000-04-06
JP5563041B2 (ja) 2014-07-30
HK1059572A1 (en) 2004-07-09
JP2002525317A (ja) 2002-08-13
CY1115759T1 (el) 2017-01-25
EP1117401A2 (en) 2001-07-25
AU1310100A (en) 2000-04-17
ATE254458T1 (de) 2003-12-15
AU762827B2 (en) 2003-07-03
KR101463243B1 (ko) 2014-12-17
HK1038691B (en) 2004-04-23
EP2269602B1 (en) 2014-11-19
DK1384478T3 (da) 2011-05-23
EP1384478A1 (en) 2004-01-28
PT2796138T (pt) 2016-09-22
HK1150756A1 (en) 2012-01-13
CN1320035A (zh) 2001-10-31
DE69912972T2 (de) 2004-04-22
TR200704370T2 (tr) 2007-11-21
EP1384478B1 (en) 2011-03-16
HK1038691A1 (en) 2002-03-28
PT2301541E (pt) 2014-10-29
TWI222361B (en) 2004-10-21
TR200100883T2 (tr) 2001-10-22
BR9914151A (pt) 2001-06-26
DK2269602T3 (en) 2014-12-15
EP2269602A1 (en) 2011-01-05
ES2526521T3 (es) 2015-01-13
EP1117401B1 (en) 2003-11-19
EP2796138B1 (en) 2016-08-17
CY1115916T1 (el) 2017-01-25
DK2796138T3 (en) 2016-12-05
KR20010075138A (ko) 2001-08-09
CY1111404T1 (el) 2015-08-05
ES2207307T3 (es) 2004-05-16
DE69943287D1 (de) 2011-04-28
PT1384478E (pt) 2011-05-12
JP2009007375A (ja) 2009-01-15
AR020661A1 (es) 2002-05-22
DK1117401T3 (da) 2004-02-23
DE69912972D1 (de) 2003-12-24
BRPI9914151B8 (forum.php) 2021-05-25
WO2000018386A3 (en) 2000-06-08
BRPI9914151B1 (pt) 2017-10-03
EP2796138A1 (en) 2014-10-29
PT1117401E (pt) 2004-03-31
HK1150769A1 (en) 2012-01-13
AR081393A2 (es) 2012-08-29
PT2269602E (pt) 2014-12-29
CA2342211C (en) 2009-05-26
CN1650863A (zh) 2005-08-10
CA2774207A1 (en) 2000-04-06
CA2342211A1 (en) 2000-04-06
CN1184968C (zh) 2005-01-19
JP2013018799A (ja) 2013-01-31
CN100374114C (zh) 2008-03-12
ES2602956T3 (es) 2017-02-23
ATE501732T1 (de) 2011-04-15
EP2301541A1 (en) 2011-03-30

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