ES2465668T3 - Anticuerpos monoclonales humanizados para el factor de crecimiento de hepatocitos - Google Patents
Anticuerpos monoclonales humanizados para el factor de crecimiento de hepatocitos Download PDFInfo
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- ES2465668T3 ES2465668T3 ES07759598.1T ES07759598T ES2465668T3 ES 2465668 T3 ES2465668 T3 ES 2465668T3 ES 07759598 T ES07759598 T ES 07759598T ES 2465668 T3 ES2465668 T3 ES 2465668T3
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Classifications
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- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/22—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/71—Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
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- General Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
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- Pharmacology & Pharmacy (AREA)
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- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Veterinary Medicine (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (3)
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| US78824306P | 2006-04-01 | 2006-04-01 | |
| US788243P | 2006-04-01 | ||
| PCT/US2007/065385 WO2007115049A2 (en) | 2006-04-01 | 2007-03-28 | Humanized monoclonal antibodies to hepatocyte growth factor |
Publications (1)
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| ES2465668T3 true ES2465668T3 (es) | 2014-06-06 |
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| ES07759598.1T Active ES2465668T3 (es) | 2006-04-01 | 2007-03-28 | Anticuerpos monoclonales humanizados para el factor de crecimiento de hepatocitos |
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| EP (2) | EP2016162B1 (OSRAM) |
| JP (1) | JP5312315B2 (OSRAM) |
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| AU (1) | AU2007233242B2 (OSRAM) |
| BR (1) | BRPI0709932A2 (OSRAM) |
| CA (1) | CA2645358C (OSRAM) |
| CO (1) | CO6140067A2 (OSRAM) |
| CR (1) | CR10308A (OSRAM) |
| ES (1) | ES2465668T3 (OSRAM) |
| GE (1) | GEP20125517B (OSRAM) |
| IL (1) | IL194221A (OSRAM) |
| MA (1) | MA30382B1 (OSRAM) |
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| MY (1) | MY145042A (OSRAM) |
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| PE (1) | PE20080008A1 (OSRAM) |
| RU (1) | RU2461570C2 (OSRAM) |
| TW (1) | TWI417300B (OSRAM) |
| UA (1) | UA94452C2 (OSRAM) |
| WO (1) | WO2007115049A2 (OSRAM) |
| ZA (1) | ZA200807903B (OSRAM) |
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| US20040208876A1 (en) * | 2003-04-18 | 2004-10-21 | Kim Kyung Jin | Monoclonal antibodies to hepatocyte growth factor |
| TW201319088A (zh) | 2003-07-18 | 2013-05-16 | Amgen Inc | 對肝細胞生長因子具專一性之結合劑 |
| JP2008545753A (ja) * | 2005-06-02 | 2008-12-18 | ギャラクシー バイオテック， エルエルシー | 抗体で脳腫瘍を処置する方法 |
| AR059922A1 (es) | 2006-04-01 | 2008-05-07 | Galaxy Biotech Llc | Anticuerpos monoclonales humanizados para el factor de crecimiento de hepatocitos |
| PL2027156T3 (pl) | 2006-06-02 | 2011-06-30 | Aveo Pharmaceuticals Inc | Białka wiążące czynnik wzrostowy hapatocytów (HGF) |
| AR061170A1 (es) | 2006-06-02 | 2008-08-06 | Aveo Pharmaceuticals Inc | Proteinas que se unen con el factor de crecimiento de hepatocitos (hgf) |
| PL2032166T3 (pl) | 2006-06-13 | 2013-09-30 | Oncomed Pharm Inc | Kompozycje i sposoby diagnozowania i leczenia nowotworów |
| CA2676008A1 (en) | 2007-01-24 | 2008-07-31 | Oncomed Pharmaceuticals, Inc. | Compositions and methods for diagnosing and treating cancer |
| SG188802A1 (en) * | 2008-03-06 | 2013-04-30 | Genentech Inc | Combination therapy with c-met and egfr antagonists |
| EP2274153B1 (en) * | 2008-04-10 | 2012-07-04 | Objet Ltd. | System and method for three dimensional model printing |
| US20110217294A1 (en) * | 2008-04-11 | 2011-09-08 | Daniel Fults | Combination of hgf inhibitor and hedgehog inhibitor to treat cancer |
| TW201002346A (en) * | 2008-04-11 | 2010-01-16 | Galaxy Biotech Llc | Combination of HGF inhibitor and EGF inhibitor to treat cancer |
| PE20091714A1 (es) * | 2008-04-11 | 2009-11-15 | Galaxy Biotech Llc | Combinacion del inhibidor hgf y el agonista pten |
| EP2288383A1 (en) * | 2008-05-14 | 2011-03-02 | Amgen, Inc | Combinations vegf(r) inhibitors and hepatocyte growth factor (c-met) inhibitors for the treatment of cancer |
| AU2009255305B2 (en) | 2008-05-29 | 2014-10-30 | Galaxy Biotech, Llc | Monoclonal antibodies to basic fibroblast growth factor |
| CN102316897B (zh) | 2008-07-08 | 2014-11-05 | 昂考梅德药品有限公司 | Notch结合剂和拮抗剂及其应用方法 |
| US9132189B2 (en) | 2008-07-08 | 2015-09-15 | Oncomed Pharmaceuticals, Inc. | Notch1 binding agents and methods of use thereof |
| MX2011000455A (es) | 2008-11-07 | 2011-02-25 | Galaxy Biotech Llc | Anticuerpos monoclonales especificos al receptor 2 del factor de crecimiento de fibroblastos. |
| US8497358B2 (en) | 2008-12-19 | 2013-07-30 | Takeda Pharmaceutical Company Limited | Antibody purification method |
| US20120052064A1 (en) | 2009-04-17 | 2012-03-01 | Yuuki Ito | Anti-hgf antibody combinational cancer therapies |
| CA2763488A1 (en) * | 2009-05-28 | 2010-12-02 | Neil James Clarke | Antigen-binding proteins |
| AU2011205316B2 (en) | 2010-01-13 | 2015-05-28 | Oncomed Pharmaceuticals, Inc. | Notch1 binding agents and methods of use thereof |
| EP3511342B1 (en) | 2010-03-10 | 2024-01-17 | Genmab A/S | Monoclonal antibodies against c-met |
| WO2012003338A1 (en) | 2010-07-01 | 2012-01-05 | Takeda Pharmaceutical Company Limited | COMBINATION OF A cMET INHIBITOR AND AN ANTIBODY TO HGF AND/OR cMET |
| US20140057908A1 (en) | 2010-09-27 | 2014-02-27 | Exelixis, Inc. | Method of Treating Cancer |
| EP2853542A1 (en) * | 2010-11-24 | 2015-04-01 | Glaxo Group Limited | Multispecific antigen binding proteins targeting HGF |
| AU2012304362A1 (en) | 2011-09-09 | 2014-03-06 | Amgen Inc. | Use of c-Met protein for predicting the efficacy of anti-hepatocyte growth factor ("HGF") antibodies in esophageal and gastric cancer patients |
| WO2013152252A1 (en) | 2012-04-06 | 2013-10-10 | OSI Pharmaceuticals, LLC | Combination anti-cancer therapy |
| EP2873422A4 (en) | 2012-07-10 | 2015-12-30 | Takeda Pharmaceutical | PHARMACEUTICAL PREPARATION FOR INJECTION |
| EP2708556B1 (en) | 2012-09-12 | 2018-11-07 | Samsung Electronics Co., Ltd | Pharmaceutical composition for the use in a combination therapy for prevention or treatment of c-met or angiogenesis factor induced diseases |
| US9062104B2 (en) | 2013-03-14 | 2015-06-23 | Alderbio Holdings Llc | Therapeutic use of antibodies to HGF |
| US9732150B2 (en) | 2013-03-14 | 2017-08-15 | Alderbio Holdings Llc | Therapeutic use of antibodies to HGF |
| TW201438737A (zh) * | 2013-03-14 | 2014-10-16 | Alder Biopharmaceuticals Inc | Ｈｇｆ抗體之治療用途 |
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- 2007-03-26 PE PE2007000342A patent/PE20080008A1/es not_active Application Discontinuation
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- 2007-03-28 UA UAA200812789A patent/UA94452C2/ru unknown
- 2007-03-28 KR KR1020087026853A patent/KR101516289B1/ko not_active Expired - Fee Related
- 2007-03-28 EP EP07759598.1A patent/EP2016162B1/en active Active
- 2007-03-28 EP EP11192887A patent/EP2476704A3/en not_active Withdrawn
- 2007-03-28 CN CN2012105645795A patent/CN103172736A/zh active Pending
- 2007-03-28 GE GEAP200710944A patent/GEP20125517B/en unknown
- 2007-03-28 CN CN2007800123673A patent/CN101415811B/zh not_active Expired - Fee Related
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- 2007-03-28 AU AU2007233242A patent/AU2007233242B2/en not_active Ceased
- 2007-03-28 WO PCT/US2007/065385 patent/WO2007115049A2/en not_active Ceased
- 2007-03-28 ES ES07759598.1T patent/ES2465668T3/es active Active
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- 2008-09-22 CR CR10308A patent/CR10308A/es not_active Application Discontinuation
- 2008-10-17 MA MA31306A patent/MA30382B1/fr unknown
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