ES2400348T3 - Piridina-1-óxidos sustituidos con 3-aminocarbonilo, 6-fenilo como inhibidores de la quinasa P38 - Google Patents

Piridina-1-óxidos sustituidos con 3-aminocarbonilo, 6-fenilo como inhibidores de la quinasa P38 Download PDF

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Publication number
ES2400348T3
ES2400348T3 ES04763980T ES04763980T ES2400348T3 ES 2400348 T3 ES2400348 T3 ES 2400348T3 ES 04763980 T ES04763980 T ES 04763980T ES 04763980 T ES04763980 T ES 04763980T ES 2400348 T3 ES2400348 T3 ES 2400348T3
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Prior art keywords
optionally substituted
alkyl
fluoro
groups
carbonyl
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Expired - Lifetime
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ES04763980T
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English (en)
Spanish (es)
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Ann Louise Walker
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GlaxoSmithKline LLC
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GlaxoSmithKline LLC
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/89—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members with hetero atoms directly attached to the ring nitrogen atom
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ES04763980T 2003-08-11 2004-08-09 Piridina-1-óxidos sustituidos con 3-aminocarbonilo, 6-fenilo como inhibidores de la quinasa P38 Expired - Lifetime ES2400348T3 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB0318814.1A GB0318814D0 (en) 2003-08-11 2003-08-11 Novel compounds
GB0318814 2003-08-11
PCT/EP2004/008972 WO2005014550A1 (en) 2003-08-11 2004-08-09 3- aminocarbonyl, 6-phenyl substituted pyridine-1-oxides as p38 kinase inhibitors

Publications (1)

Publication Number Publication Date
ES2400348T3 true ES2400348T3 (es) 2013-04-09

Family

ID=27840005

Family Applications (1)

Application Number Title Priority Date Filing Date
ES04763980T Expired - Lifetime ES2400348T3 (es) 2003-08-11 2004-08-09 Piridina-1-óxidos sustituidos con 3-aminocarbonilo, 6-fenilo como inhibidores de la quinasa P38

Country Status (6)

Country Link
US (1) US7838540B2 (https=)
EP (1) EP1654235B1 (https=)
JP (1) JP4845733B2 (https=)
ES (1) ES2400348T3 (https=)
GB (1) GB0318814D0 (https=)
WO (1) WO2005014550A1 (https=)

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US8354435B2 (en) 2008-09-08 2013-01-15 The Board Of Trustees Of The Leland Stanford Junior University Modulators of aldehyde dehydrogenase activity and methods of use thereof
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US10457659B2 (en) 2011-04-29 2019-10-29 The Board Of Trustees Of The Leland Stanford Junior University Compositions and methods for increasing proliferation of adult salivary stem cells
RU2014152454A (ru) * 2012-07-17 2016-09-10 ГЛАКСОСМИТКЛАЙН ЭлЭлСи Производное никотинамида в лечении острого коронарного синдрома
WO2014160185A2 (en) 2013-03-14 2014-10-02 The Board Of Trustees Of The Leland Stanford Junior University Mitochondrial aldehyde dehydrogenase-2 modulators and methods of use thereof
JP7028780B2 (ja) * 2015-09-30 2022-03-02 シイエスピイシイ・チョンチ・ファーマシューティカル・テクノロジー・（シーチアチョワン）・カンパニー・リミテッド ベンズアミド誘導体
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BR112020006677A2 (pt) 2017-10-05 2020-10-06 Fulcrum Therapeutics, Inc. uso de inibidores p38 para reduzir a expressão de dux4

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