ES2400348T3 - Piridina-1-óxidos sustituidos con 3-aminocarbonilo, 6-fenilo como inhibidores de la quinasa P38 - Google Patents

Piridina-1-óxidos sustituidos con 3-aminocarbonilo, 6-fenilo como inhibidores de la quinasa P38 Download PDF

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Publication number
ES2400348T3
ES2400348T3 ES04763980T ES04763980T ES2400348T3 ES 2400348 T3 ES2400348 T3 ES 2400348T3 ES 04763980 T ES04763980 T ES 04763980T ES 04763980 T ES04763980 T ES 04763980T ES 2400348 T3 ES2400348 T3 ES 2400348T3
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optionally substituted
alkyl
fluoro
groups
carbonyl
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ES04763980T
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Spanish (es)
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Ann Louise Walker
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GlaxoSmithKline LLC
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GlaxoSmithKline LLC
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
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    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/89—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members with hetero atoms directly attached to the ring nitrogen atom
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ES04763980T 2003-08-11 2004-08-09 Piridina-1-óxidos sustituidos con 3-aminocarbonilo, 6-fenilo como inhibidores de la quinasa P38 Expired - Lifetime ES2400348T3 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB0318814.1A GB0318814D0 (en) 2003-08-11 2003-08-11 Novel compounds
GB0318814 2003-08-11
PCT/EP2004/008972 WO2005014550A1 (en) 2003-08-11 2004-08-09 3- aminocarbonyl, 6-phenyl substituted pyridine-1-oxides as p38 kinase inhibitors

Publications (1)

Publication Number Publication Date
ES2400348T3 true ES2400348T3 (es) 2013-04-09

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ID=27840005

Family Applications (1)

Application Number Title Priority Date Filing Date
ES04763980T Expired - Lifetime ES2400348T3 (es) 2003-08-11 2004-08-09 Piridina-1-óxidos sustituidos con 3-aminocarbonilo, 6-fenilo como inhibidores de la quinasa P38

Country Status (6)

Country Link
US (1) US7838540B2 (https=)
EP (1) EP1654235B1 (https=)
JP (1) JP4845733B2 (https=)
ES (1) ES2400348T3 (https=)
GB (1) GB0318814D0 (https=)
WO (1) WO2005014550A1 (https=)

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EP2337563B1 (en) * 2008-09-08 2014-04-09 The Board of Trustees of The Leland Stanford Junior University Modulators of aldehyde dehydrogenase activity and methods of use thereof
KR20110082180A (ko) 2008-10-28 2011-07-18 더 보드 오브 트러스티스 오브 더 리랜드 스탠포드 쥬니어 유니버시티 알데히드 탈수소효소의 조절자 및 그것의 사용방법
WO2012149106A1 (en) 2011-04-29 2012-11-01 The Board Of Trustees Of The Leland Stanford Junior University Compositions and methods for increasing proliferation of adult salivary stem cells
CA2879222A1 (en) * 2012-07-17 2014-01-23 Glaxosmithkline Llc Nicotinamide derivate in the treatment of acute coronary syndrome
JP6410790B2 (ja) 2013-03-14 2018-10-24 ザ ボード オブ トラスティーズ オブ ザ レランド スタンフォード ジュニア ユニバーシティー ミトコンドリアアルデヒドデヒドロゲナーゼ−２調節因子およびその使用方法
CN106554314B (zh) * 2015-09-30 2021-07-27 石药集团中奇制药技术（石家庄）有限公司 苯甲酰胺类衍生物
WO2019071147A1 (en) 2017-10-05 2019-04-11 Fulcrum Therapeutics, Inc. INHIBITORS OF KINASE P38 REDUCING EXPRESSION OF DUX4 GENE AND DOWNSTREAM GENES FOR THE TREATMENT OF FSHD
US10342786B2 (en) 2017-10-05 2019-07-09 Fulcrum Therapeutics, Inc. P38 kinase inhibitors reduce DUX4 and downstream gene expression for the treatment of FSHD

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US7838540B2 (en) 2010-11-23
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