ES2395930T3 - Procedimiento estereoselectivo y formas cristalinas de una camptotecina - Google Patents

Procedimiento estereoselectivo y formas cristalinas de una camptotecina Download PDF

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Publication number
ES2395930T3
ES2395930T3 ES05849781T ES05849781T ES2395930T3 ES 2395930 T3 ES2395930 T3 ES 2395930T3 ES 05849781 T ES05849781 T ES 05849781T ES 05849781 T ES05849781 T ES 05849781T ES 2395930 T3 ES2395930 T3 ES 2395930T3
Authority
ES
Spain
Prior art keywords
camptothecin
process according
butyloxyiminomethyl
ray diffraction
compound according
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES05849781T
Other languages
English (en)
Spanish (es)
Inventor
Paolo Carminati
Maria Ornella Tinti
Mauro Marzi
Fabrizio Giorgi
Walter Cabri
Marco Alpegiani
Domenico Vergani
Paolo Ghetti
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sigma Tau Industrie Farmaceutiche Riunite SpA
Original Assignee
Sigma Tau Industrie Farmaceutiche Riunite SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sigma Tau Industrie Farmaceutiche Riunite SpA filed Critical Sigma Tau Industrie Farmaceutiche Riunite SpA
Application granted granted Critical
Publication of ES2395930T3 publication Critical patent/ES2395930T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/12—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
    • C07D491/14—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/22—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains four or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Saccharide Compounds (AREA)
ES05849781T 2004-12-21 2005-12-16 Procedimiento estereoselectivo y formas cristalinas de una camptotecina Expired - Lifetime ES2395930T3 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP04030246 2004-12-21
EP04030246 2004-12-21
PCT/EP2005/056849 WO2006067092A2 (en) 2004-12-21 2005-12-16 Stereoselective process and crystalline forms of a camptothecin

Publications (1)

Publication Number Publication Date
ES2395930T3 true ES2395930T3 (es) 2013-02-18

Family

ID=34927884

Family Applications (1)

Application Number Title Priority Date Filing Date
ES05849781T Expired - Lifetime ES2395930T3 (es) 2004-12-21 2005-12-16 Procedimiento estereoselectivo y formas cristalinas de una camptotecina

Country Status (18)

Country Link
US (3) US7799921B2 (enExample)
EP (1) EP1828196B1 (enExample)
JP (2) JP5491699B2 (enExample)
KR (1) KR101355121B1 (enExample)
CN (1) CN101084221B (enExample)
AU (1) AU2005318227B2 (enExample)
BR (1) BRPI0515832A (enExample)
CA (1) CA2590756C (enExample)
CY (1) CY1117243T1 (enExample)
DK (1) DK1828196T3 (enExample)
ES (1) ES2395930T3 (enExample)
HR (1) HRP20120926T1 (enExample)
ME (1) ME01495B (enExample)
PL (1) PL1828196T3 (enExample)
PT (1) PT1828196E (enExample)
RS (1) RS52585B (enExample)
SI (1) SI1828196T1 (enExample)
WO (1) WO2006067092A2 (enExample)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1828196B1 (en) * 2004-12-21 2012-10-17 SIGMA-TAU Industrie Farmaceutiche Riunite S.p.A. Stereoselective process and crystalline forms of a camptothecin
ITRM20050418A1 (it) * 2005-08-04 2007-02-05 Sigma Tau Ind Farmaceuti Sistemi terapeutici a rilascio immediato per il migliorato assorbimento orale di 7-[(e)-t-butilossimminometil] camptotecina.
FR2938534B1 (fr) 2008-11-14 2012-10-26 Sanofi Aventis Procede de preparation de l'hemifumarate d'eplivanserine

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH03271278A (ja) * 1990-03-16 1991-12-03 Nissan Chem Ind Ltd ２―アニリノピリミジン誘導体および農園芸用殺菌剤
JP3046401B2 (ja) * 1991-06-18 2000-05-29 イハラケミカル工業株式会社 ６−〔１−（ｎ−アルコキシイミノ）エチル〕サリチル酸誘導体及びその製造法
IL106786A (en) * 1992-09-10 1997-02-18 Basf Ag Substituted pyridine derivatives and fungicidal compositions containing them
EP1044977B1 (en) * 1999-03-09 2002-05-02 Sigma-Tau Industrie Farmaceutiche Riunite S.p.A. Camptothecin derivatives having antitumor activity
AU2003215594A1 (en) * 2002-03-01 2003-09-16 Pharmacia Italia S.P.A. Crystalline polymorphic form of irinotecan hydrochloride
EP1828196B1 (en) * 2004-12-21 2012-10-17 SIGMA-TAU Industrie Farmaceutiche Riunite S.p.A. Stereoselective process and crystalline forms of a camptothecin

Also Published As

Publication number Publication date
US20100311783A1 (en) 2010-12-09
HK1113487A1 (en) 2008-10-03
WO2006067092A3 (en) 2006-11-02
EP1828196A2 (en) 2007-09-05
RS52585B (sr) 2013-04-30
US7799921B2 (en) 2010-09-21
CN101084221B (zh) 2011-05-11
PL1828196T3 (pl) 2013-02-28
AU2005318227A1 (en) 2006-06-29
EP1828196B1 (en) 2012-10-17
KR101355121B1 (ko) 2014-01-24
JP5982261B2 (ja) 2016-08-31
CN101084221A (zh) 2007-12-05
US8124769B2 (en) 2012-02-28
PT1828196E (pt) 2012-11-19
KR20070097535A (ko) 2007-10-04
CY1117243T1 (el) 2017-04-05
US20090239893A1 (en) 2009-09-24
JP2013067629A (ja) 2013-04-18
ME01495B (me) 2014-04-20
DK1828196T3 (da) 2012-11-26
BRPI0515832A (pt) 2008-08-05
CA2590756C (en) 2014-09-02
US20100311784A1 (en) 2010-12-09
JP5491699B2 (ja) 2014-05-14
JP2008524306A (ja) 2008-07-10
CA2590756A1 (en) 2006-06-29
WO2006067092A2 (en) 2006-06-29
HRP20120926T1 (hr) 2012-12-31
SI1828196T1 (sl) 2012-12-31
AU2005318227B2 (en) 2011-08-18
US8101758B2 (en) 2012-01-24

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