DK1828196T3 - Stereospecifik fremgangsmåde og krystallinske former af en camptothecin - Google Patents

Stereospecifik fremgangsmåde og krystallinske former af en camptothecin

Info

Publication number
DK1828196T3
DK1828196T3 DK05849781.9T DK05849781T DK1828196T3 DK 1828196 T3 DK1828196 T3 DK 1828196T3 DK 05849781 T DK05849781 T DK 05849781T DK 1828196 T3 DK1828196 T3 DK 1828196T3
Authority
DK
Denmark
Prior art keywords
camptothecin
crystalline forms
stereospecific method
stereospecific
crystalline
Prior art date
Application number
DK05849781.9T
Other languages
Danish (da)
English (en)
Inventor
Paolo Carminati
Maria Ornella Tinti
Mauro Marzi
Fabrizio Giorgi
Walter Cabri
Marco Alpegiani
Domenico Vergani
Paolo Ghetti
Original Assignee
Sigma Tau Ind Farmaceuti
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sigma Tau Ind Farmaceuti filed Critical Sigma Tau Ind Farmaceuti
Application granted granted Critical
Publication of DK1828196T3 publication Critical patent/DK1828196T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/12—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
    • C07D491/14—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/22—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains four or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Saccharide Compounds (AREA)
DK05849781.9T 2004-12-21 2005-12-16 Stereospecifik fremgangsmåde og krystallinske former af en camptothecin DK1828196T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP04030246 2004-12-21
PCT/EP2005/056849 WO2006067092A2 (en) 2004-12-21 2005-12-16 Stereoselective process and crystalline forms of a camptothecin

Publications (1)

Publication Number Publication Date
DK1828196T3 true DK1828196T3 (da) 2012-11-26

Family

ID=34927884

Family Applications (1)

Application Number Title Priority Date Filing Date
DK05849781.9T DK1828196T3 (da) 2004-12-21 2005-12-16 Stereospecifik fremgangsmåde og krystallinske former af en camptothecin

Country Status (18)

Country Link
US (3) US7799921B2 (enExample)
EP (1) EP1828196B1 (enExample)
JP (2) JP5491699B2 (enExample)
KR (1) KR101355121B1 (enExample)
CN (1) CN101084221B (enExample)
AU (1) AU2005318227B2 (enExample)
BR (1) BRPI0515832A (enExample)
CA (1) CA2590756C (enExample)
CY (1) CY1117243T1 (enExample)
DK (1) DK1828196T3 (enExample)
ES (1) ES2395930T3 (enExample)
HR (1) HRP20120926T1 (enExample)
ME (1) ME01495B (enExample)
PL (1) PL1828196T3 (enExample)
PT (1) PT1828196E (enExample)
RS (1) RS52585B (enExample)
SI (1) SI1828196T1 (enExample)
WO (1) WO2006067092A2 (enExample)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1828196B1 (en) * 2004-12-21 2012-10-17 SIGMA-TAU Industrie Farmaceutiche Riunite S.p.A. Stereoselective process and crystalline forms of a camptothecin
ITRM20050418A1 (it) * 2005-08-04 2007-02-05 Sigma Tau Ind Farmaceuti Sistemi terapeutici a rilascio immediato per il migliorato assorbimento orale di 7-[(e)-t-butilossimminometil] camptotecina.
FR2938534B1 (fr) 2008-11-14 2012-10-26 Sanofi Aventis Procede de preparation de l'hemifumarate d'eplivanserine

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH03271278A (ja) * 1990-03-16 1991-12-03 Nissan Chem Ind Ltd ２―アニリノピリミジン誘導体および農園芸用殺菌剤
JP3046401B2 (ja) * 1991-06-18 2000-05-29 イハラケミカル工業株式会社 ６−〔１−（ｎ−アルコキシイミノ）エチル〕サリチル酸誘導体及びその製造法
IL106786A (en) * 1992-09-10 1997-02-18 Basf Ag Substituted pyridine derivatives and fungicidal compositions containing them
EP1044977B1 (en) * 1999-03-09 2002-05-02 Sigma-Tau Industrie Farmaceutiche Riunite S.p.A. Camptothecin derivatives having antitumor activity
AU2003215594A1 (en) * 2002-03-01 2003-09-16 Pharmacia Italia S.P.A. Crystalline polymorphic form of irinotecan hydrochloride
EP1828196B1 (en) * 2004-12-21 2012-10-17 SIGMA-TAU Industrie Farmaceutiche Riunite S.p.A. Stereoselective process and crystalline forms of a camptothecin

Also Published As

Publication number Publication date
US20100311783A1 (en) 2010-12-09
HK1113487A1 (en) 2008-10-03
WO2006067092A3 (en) 2006-11-02
EP1828196A2 (en) 2007-09-05
RS52585B (sr) 2013-04-30
US7799921B2 (en) 2010-09-21
CN101084221B (zh) 2011-05-11
PL1828196T3 (pl) 2013-02-28
AU2005318227A1 (en) 2006-06-29
EP1828196B1 (en) 2012-10-17
ES2395930T3 (es) 2013-02-18
KR101355121B1 (ko) 2014-01-24
JP5982261B2 (ja) 2016-08-31
CN101084221A (zh) 2007-12-05
US8124769B2 (en) 2012-02-28
PT1828196E (pt) 2012-11-19
KR20070097535A (ko) 2007-10-04
CY1117243T1 (el) 2017-04-05
US20090239893A1 (en) 2009-09-24
JP2013067629A (ja) 2013-04-18
ME01495B (me) 2014-04-20
BRPI0515832A (pt) 2008-08-05
CA2590756C (en) 2014-09-02
US20100311784A1 (en) 2010-12-09
JP5491699B2 (ja) 2014-05-14
JP2008524306A (ja) 2008-07-10
CA2590756A1 (en) 2006-06-29
WO2006067092A2 (en) 2006-06-29
HRP20120926T1 (hr) 2012-12-31
SI1828196T1 (sl) 2012-12-31
AU2005318227B2 (en) 2011-08-18
US8101758B2 (en) 2012-01-24

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