PL1828196T3 - Stereoselektywny sposób wytwarzania i krystaliczne formy kamptotecyny - Google Patents
Stereoselektywny sposób wytwarzania i krystaliczne formy kamptotecynyInfo
- Publication number
- PL1828196T3 PL1828196T3 PL05849781T PL05849781T PL1828196T3 PL 1828196 T3 PL1828196 T3 PL 1828196T3 PL 05849781 T PL05849781 T PL 05849781T PL 05849781 T PL05849781 T PL 05849781T PL 1828196 T3 PL1828196 T3 PL 1828196T3
- Authority
- PL
- Poland
- Prior art keywords
- camptothecin
- crystalline forms
- stereoselective process
- stereoselective
- crystalline
- Prior art date
Links
- KLWPJMFMVPTNCC-UHFFFAOYSA-N Camptothecin Natural products CCC1(O)C(=O)OCC2=C1C=C3C4Nc5ccccc5C=C4CN3C2=O KLWPJMFMVPTNCC-UHFFFAOYSA-N 0.000 title 1
- VSJKWCGYPAHWDS-FQEVSTJZSA-N camptothecin Chemical compound C1=CC=C2C=C(CN3C4=CC5=C(C3=O)COC(=O)[C@]5(O)CC)C4=NC2=C1 VSJKWCGYPAHWDS-FQEVSTJZSA-N 0.000 title 1
- 229940127093 camptothecin Drugs 0.000 title 1
- VSJKWCGYPAHWDS-UHFFFAOYSA-N dl-camptothecin Natural products C1=CC=C2C=C(CN3C4=CC5=C(C3=O)COC(=O)C5(O)CC)C4=NC2=C1 VSJKWCGYPAHWDS-UHFFFAOYSA-N 0.000 title 1
- 230000000707 stereoselective effect Effects 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/12—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
- C07D491/14—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/22—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains four or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Oncology (AREA)
- Hematology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP04030246 | 2004-12-21 | ||
| PCT/EP2005/056849 WO2006067092A2 (en) | 2004-12-21 | 2005-12-16 | Stereoselective process and crystalline forms of a camptothecin |
| EP05849781A EP1828196B1 (en) | 2004-12-21 | 2005-12-16 | Stereoselective process and crystalline forms of a camptothecin |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL1828196T3 true PL1828196T3 (pl) | 2013-02-28 |
Family
ID=34927884
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL05849781T PL1828196T3 (pl) | 2004-12-21 | 2005-12-16 | Stereoselektywny sposób wytwarzania i krystaliczne formy kamptotecyny |
Country Status (18)
| Country | Link |
|---|---|
| US (3) | US7799921B2 (enExample) |
| EP (1) | EP1828196B1 (enExample) |
| JP (2) | JP5491699B2 (enExample) |
| KR (1) | KR101355121B1 (enExample) |
| CN (1) | CN101084221B (enExample) |
| AU (1) | AU2005318227B2 (enExample) |
| BR (1) | BRPI0515832A (enExample) |
| CA (1) | CA2590756C (enExample) |
| CY (1) | CY1117243T1 (enExample) |
| DK (1) | DK1828196T3 (enExample) |
| ES (1) | ES2395930T3 (enExample) |
| HR (1) | HRP20120926T1 (enExample) |
| ME (1) | ME01495B (enExample) |
| PL (1) | PL1828196T3 (enExample) |
| PT (1) | PT1828196E (enExample) |
| RS (1) | RS52585B (enExample) |
| SI (1) | SI1828196T1 (enExample) |
| WO (1) | WO2006067092A2 (enExample) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1828196B1 (en) * | 2004-12-21 | 2012-10-17 | SIGMA-TAU Industrie Farmaceutiche Riunite S.p.A. | Stereoselective process and crystalline forms of a camptothecin |
| ITRM20050418A1 (it) * | 2005-08-04 | 2007-02-05 | Sigma Tau Ind Farmaceuti | Sistemi terapeutici a rilascio immediato per il migliorato assorbimento orale di 7-[(e)-t-butilossimminometil] camptotecina. |
| FR2938534B1 (fr) | 2008-11-14 | 2012-10-26 | Sanofi Aventis | Procede de preparation de l'hemifumarate d'eplivanserine |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH03271278A (ja) * | 1990-03-16 | 1991-12-03 | Nissan Chem Ind Ltd | ２―アニリノピリミジン誘導体および農園芸用殺菌剤 |
| JP3046401B2 (ja) * | 1991-06-18 | 2000-05-29 | イハラケミカル工業株式会社 | ６−〔１−（ｎ−アルコキシイミノ）エチル〕サリチル酸誘導体及びその製造法 |
| IL106786A (en) * | 1992-09-10 | 1997-02-18 | Basf Ag | Substituted pyridine derivatives and fungicidal compositions containing them |
| EP1044977B1 (en) * | 1999-03-09 | 2002-05-02 | Sigma-Tau Industrie Farmaceutiche Riunite S.p.A. | Camptothecin derivatives having antitumor activity |
| AU2003215594A1 (en) * | 2002-03-01 | 2003-09-16 | Pharmacia Italia S.P.A. | Crystalline polymorphic form of irinotecan hydrochloride |
| EP1828196B1 (en) * | 2004-12-21 | 2012-10-17 | SIGMA-TAU Industrie Farmaceutiche Riunite S.p.A. | Stereoselective process and crystalline forms of a camptothecin |
-
2005
- 2005-12-16 EP EP05849781A patent/EP1828196B1/en not_active Expired - Lifetime
- 2005-12-16 HR HRP20120926TT patent/HRP20120926T1/hr unknown
- 2005-12-16 ME MEP-2012-128A patent/ME01495B/me unknown
- 2005-12-16 PT PT05849781T patent/PT1828196E/pt unknown
- 2005-12-16 DK DK05849781.9T patent/DK1828196T3/da active
- 2005-12-16 CA CA2590756A patent/CA2590756C/en not_active Expired - Fee Related
- 2005-12-16 ES ES05849781T patent/ES2395930T3/es not_active Expired - Lifetime
- 2005-12-16 KR KR1020077016814A patent/KR101355121B1/ko not_active Expired - Fee Related
- 2005-12-16 PL PL05849781T patent/PL1828196T3/pl unknown
- 2005-12-16 SI SI200531610T patent/SI1828196T1/sl unknown
- 2005-12-16 AU AU2005318227A patent/AU2005318227B2/en not_active Ceased
- 2005-12-16 CN CN2005800440829A patent/CN101084221B/zh not_active Expired - Lifetime
- 2005-12-16 WO PCT/EP2005/056849 patent/WO2006067092A2/en not_active Ceased
- 2005-12-16 RS RS20120505A patent/RS52585B/sr unknown
- 2005-12-16 US US11/721,282 patent/US7799921B2/en not_active Expired - Fee Related
- 2005-12-16 JP JP2007547467A patent/JP5491699B2/ja not_active Expired - Fee Related
- 2005-12-16 BR BRPI0515832-0A patent/BRPI0515832A/pt not_active Application Discontinuation
-
2010
- 2010-08-17 US US12/857,743 patent/US8124769B2/en not_active Expired - Fee Related
- 2010-08-17 US US12/857,776 patent/US8101758B2/en not_active Expired - Fee Related
-
2012
- 2012-10-30 CY CY20121101034T patent/CY1117243T1/el unknown
- 2012-11-09 JP JP2012247587A patent/JP5982261B2/ja not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| US20100311783A1 (en) | 2010-12-09 |
| HK1113487A1 (en) | 2008-10-03 |
| WO2006067092A3 (en) | 2006-11-02 |
| EP1828196A2 (en) | 2007-09-05 |
| RS52585B (sr) | 2013-04-30 |
| US7799921B2 (en) | 2010-09-21 |
| CN101084221B (zh) | 2011-05-11 |
| AU2005318227A1 (en) | 2006-06-29 |
| EP1828196B1 (en) | 2012-10-17 |
| ES2395930T3 (es) | 2013-02-18 |
| KR101355121B1 (ko) | 2014-01-24 |
| JP5982261B2 (ja) | 2016-08-31 |
| CN101084221A (zh) | 2007-12-05 |
| US8124769B2 (en) | 2012-02-28 |
| PT1828196E (pt) | 2012-11-19 |
| KR20070097535A (ko) | 2007-10-04 |
| CY1117243T1 (el) | 2017-04-05 |
| US20090239893A1 (en) | 2009-09-24 |
| JP2013067629A (ja) | 2013-04-18 |
| ME01495B (me) | 2014-04-20 |
| DK1828196T3 (da) | 2012-11-26 |
| BRPI0515832A (pt) | 2008-08-05 |
| CA2590756C (en) | 2014-09-02 |
| US20100311784A1 (en) | 2010-12-09 |
| JP5491699B2 (ja) | 2014-05-14 |
| JP2008524306A (ja) | 2008-07-10 |
| CA2590756A1 (en) | 2006-06-29 |
| WO2006067092A2 (en) | 2006-06-29 |
| HRP20120926T1 (hr) | 2012-12-31 |
| SI1828196T1 (sl) | 2012-12-31 |
| AU2005318227B2 (en) | 2011-08-18 |
| US8101758B2 (en) | 2012-01-24 |
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