ES2389945T3 - Remodelación criogénica subdérmica de músculos, nervios, tejido conectivo, y/o tejido adiposo (grasa) - Google Patents
Remodelación criogénica subdérmica de músculos, nervios, tejido conectivo, y/o tejido adiposo (grasa) Download PDFInfo
- Publication number
- ES2389945T3 ES2389945T3 ES06770671T ES06770671T ES2389945T3 ES 2389945 T3 ES2389945 T3 ES 2389945T3 ES 06770671 T ES06770671 T ES 06770671T ES 06770671 T ES06770671 T ES 06770671T ES 2389945 T3 ES2389945 T3 ES 2389945T3
- Authority
- ES
- Spain
- Prior art keywords
- probe
- cooling
- tissue
- skin
- muscle
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 210000003205 muscle Anatomy 0.000 title claims abstract description 122
- 238000007634 remodeling Methods 0.000 title claims description 37
- 210000005036 nerve Anatomy 0.000 title description 22
- 210000002808 connective tissue Anatomy 0.000 title description 14
- 210000000577 adipose tissue Anatomy 0.000 title description 12
- 210000001519 tissue Anatomy 0.000 claims abstract description 210
- 239000000523 sample Substances 0.000 claims abstract description 170
- 238000001816 cooling Methods 0.000 claims abstract description 81
- 239000012809 cooling fluid Substances 0.000 claims abstract description 70
- 230000000149 penetrating effect Effects 0.000 claims abstract description 37
- 239000012530 fluid Substances 0.000 claims abstract description 29
- 230000006378 damage Effects 0.000 claims abstract description 24
- 230000037303 wrinkles Effects 0.000 claims abstract description 24
- 239000000463 material Substances 0.000 claims abstract description 22
- 208000027418 Wounds and injury Diseases 0.000 claims abstract description 16
- 208000014674 injury Diseases 0.000 claims abstract description 16
- 230000008602 contraction Effects 0.000 claims abstract description 15
- 230000004118 muscle contraction Effects 0.000 claims abstract description 14
- 238000004891 communication Methods 0.000 claims abstract description 5
- 239000011159 matrix material Substances 0.000 claims abstract description 5
- 238000011282 treatment Methods 0.000 claims description 119
- 230000003902 lesion Effects 0.000 claims description 13
- 230000004044 response Effects 0.000 claims description 13
- 230000008859 change Effects 0.000 claims description 11
- 238000001802 infusion Methods 0.000 claims description 11
- 239000002577 cryoprotective agent Substances 0.000 claims description 7
- 238000000926 separation method Methods 0.000 claims description 6
- 239000003978 infusion fluid Substances 0.000 claims description 4
- 108091026890 Coding region Proteins 0.000 claims 1
- 210000003491 skin Anatomy 0.000 description 106
- GQPLMRYTRLFLPF-UHFFFAOYSA-N Nitrous Oxide Chemical compound [O-][N+]#N GQPLMRYTRLFLPF-UHFFFAOYSA-N 0.000 description 32
- 238000000034 method Methods 0.000 description 30
- 239000002537 cosmetic Substances 0.000 description 29
- 230000000694 effects Effects 0.000 description 28
- 230000006907 apoptotic process Effects 0.000 description 27
- 206010040954 Skin wrinkling Diseases 0.000 description 25
- IAZDPXIOMUYVGZ-UHFFFAOYSA-N Dimethylsulphoxide Chemical compound CS(C)=O IAZDPXIOMUYVGZ-UHFFFAOYSA-N 0.000 description 19
- 239000007788 liquid Substances 0.000 description 19
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 15
- 230000007774 longterm Effects 0.000 description 13
- 210000004027 cell Anatomy 0.000 description 12
- 238000010438 heat treatment Methods 0.000 description 11
- 230000007246 mechanism Effects 0.000 description 11
- 230000017074 necrotic cell death Effects 0.000 description 10
- 230000009467 reduction Effects 0.000 description 10
- 208000035484 Cellulite Diseases 0.000 description 9
- 206010049752 Peau d'orange Diseases 0.000 description 9
- 230000036232 cellulite Effects 0.000 description 9
- 230000035876 healing Effects 0.000 description 9
- 239000000126 substance Substances 0.000 description 9
- 239000007924 injection Substances 0.000 description 8
- 238000002347 injection Methods 0.000 description 8
- 102000008186 Collagen Human genes 0.000 description 7
- 108010035532 Collagen Proteins 0.000 description 7
- 230000015572 biosynthetic process Effects 0.000 description 7
- 229920001436 collagen Polymers 0.000 description 7
- 230000007547 defect Effects 0.000 description 7
- 239000007789 gas Substances 0.000 description 7
- 230000001976 improved effect Effects 0.000 description 7
- 230000007838 tissue remodeling Effects 0.000 description 7
- 206010061218 Inflammation Diseases 0.000 description 6
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 description 6
- 229940079593 drug Drugs 0.000 description 6
- 239000003814 drug Substances 0.000 description 6
- 230000004054 inflammatory process Effects 0.000 description 6
- 230000033001 locomotion Effects 0.000 description 6
- 239000000203 mixture Substances 0.000 description 6
- 230000008439 repair process Effects 0.000 description 6
- 229910001220 stainless steel Inorganic materials 0.000 description 6
- 239000010935 stainless steel Substances 0.000 description 6
- 241000225674 Procerus Species 0.000 description 5
- 230000036770 blood supply Effects 0.000 description 5
- 150000001875 compounds Chemical class 0.000 description 5
- 239000004020 conductor Substances 0.000 description 5
- 230000000959 cryoprotective effect Effects 0.000 description 5
- 210000002615 epidermis Anatomy 0.000 description 5
- 230000006870 function Effects 0.000 description 5
- 230000005764 inhibitory process Effects 0.000 description 5
- 238000009413 insulation Methods 0.000 description 5
- 210000001087 myotubule Anatomy 0.000 description 5
- 210000002435 tendon Anatomy 0.000 description 5
- 238000002560 therapeutic procedure Methods 0.000 description 5
- 101710117542 Botulinum neurotoxin type A Proteins 0.000 description 4
- 102000016942 Elastin Human genes 0.000 description 4
- 108010014258 Elastin Proteins 0.000 description 4
- 230000006399 behavior Effects 0.000 description 4
- 230000008901 benefit Effects 0.000 description 4
- 210000004204 blood vessel Anatomy 0.000 description 4
- 229940089093 botox Drugs 0.000 description 4
- 230000008878 coupling Effects 0.000 description 4
- 238000010168 coupling process Methods 0.000 description 4
- 238000005859 coupling reaction Methods 0.000 description 4
- 210000004207 dermis Anatomy 0.000 description 4
- 238000011161 development Methods 0.000 description 4
- 230000018109 developmental process Effects 0.000 description 4
- 230000002500 effect on skin Effects 0.000 description 4
- 229920002549 elastin Polymers 0.000 description 4
- 230000010102 embolization Effects 0.000 description 4
- 230000002401 inhibitory effect Effects 0.000 description 4
- 210000003041 ligament Anatomy 0.000 description 4
- 210000000715 neuromuscular junction Anatomy 0.000 description 4
- 230000002829 reductive effect Effects 0.000 description 4
- 239000003507 refrigerant Substances 0.000 description 4
- 231100000241 scar Toxicity 0.000 description 4
- 230000002792 vascular Effects 0.000 description 4
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 3
- 206010021143 Hypoxia Diseases 0.000 description 3
- 241000223503 Platysma Species 0.000 description 3
- 230000001640 apoptogenic effect Effects 0.000 description 3
- 238000003782 apoptosis assay Methods 0.000 description 3
- 230000000975 bioactive effect Effects 0.000 description 3
- 230000008828 contractile function Effects 0.000 description 3
- 238000005520 cutting process Methods 0.000 description 3
- 210000000744 eyelid Anatomy 0.000 description 3
- 239000004744 fabric Substances 0.000 description 3
- 230000007954 hypoxia Effects 0.000 description 3
- 230000001939 inductive effect Effects 0.000 description 3
- 230000002045 lasting effect Effects 0.000 description 3
- 238000004519 manufacturing process Methods 0.000 description 3
- 210000002161 motor neuron Anatomy 0.000 description 3
- 230000005522 programmed cell death Effects 0.000 description 3
- 230000037390 scarring Effects 0.000 description 3
- 210000001057 smooth muscle myoblast Anatomy 0.000 description 3
- 230000007704 transition Effects 0.000 description 3
- 238000009834 vaporization Methods 0.000 description 3
- 230000008016 vaporization Effects 0.000 description 3
- CURLTUGMZLYLDI-UHFFFAOYSA-N Carbon dioxide Chemical compound O=C=O CURLTUGMZLYLDI-UHFFFAOYSA-N 0.000 description 2
- 208000032544 Cicatrix Diseases 0.000 description 2
- 208000034656 Contusions Diseases 0.000 description 2
- 208000007101 Muscle Cramp Diseases 0.000 description 2
- 208000002193 Pain Diseases 0.000 description 2
- 206010033799 Paralysis Diseases 0.000 description 2
- XUIMIQQOPSSXEZ-UHFFFAOYSA-N Silicon Chemical compound [Si] XUIMIQQOPSSXEZ-UHFFFAOYSA-N 0.000 description 2
- 208000005392 Spasm Diseases 0.000 description 2
- OIPILFWXSMYKGL-UHFFFAOYSA-N acetylcholine Chemical compound CC(=O)OCC[N+](C)(C)C OIPILFWXSMYKGL-UHFFFAOYSA-N 0.000 description 2
- 229960004373 acetylcholine Drugs 0.000 description 2
- 210000003050 axon Anatomy 0.000 description 2
- 230000033228 biological regulation Effects 0.000 description 2
- 230000005540 biological transmission Effects 0.000 description 2
- 230000000903 blocking effect Effects 0.000 description 2
- 239000008280 blood Substances 0.000 description 2
- 210000004369 blood Anatomy 0.000 description 2
- 238000009835 boiling Methods 0.000 description 2
- 210000000988 bone and bone Anatomy 0.000 description 2
- 229910052799 carbon Inorganic materials 0.000 description 2
- 230000005779 cell damage Effects 0.000 description 2
- 230000030833 cell death Effects 0.000 description 2
- 208000037887 cell injury Diseases 0.000 description 2
- 238000010586 diagram Methods 0.000 description 2
- 230000002708 enhancing effect Effects 0.000 description 2
- 210000001097 facial muscle Anatomy 0.000 description 2
- 210000003195 fascia Anatomy 0.000 description 2
- 230000012010 growth Effects 0.000 description 2
- 210000003128 head Anatomy 0.000 description 2
- 239000000819 hypertonic solution Substances 0.000 description 2
- 229940021223 hypertonic solution Drugs 0.000 description 2
- 230000006872 improvement Effects 0.000 description 2
- 230000002779 inactivation Effects 0.000 description 2
- 239000012528 membrane Substances 0.000 description 2
- 238000000694 mesotherapy Methods 0.000 description 2
- 210000000663 muscle cell Anatomy 0.000 description 2
- 230000004220 muscle function Effects 0.000 description 2
- 210000003365 myofibril Anatomy 0.000 description 2
- 230000001338 necrotic effect Effects 0.000 description 2
- 210000000944 nerve tissue Anatomy 0.000 description 2
- 210000000118 neural pathway Anatomy 0.000 description 2
- 230000010004 neural pathway Effects 0.000 description 2
- 206010033675 panniculitis Diseases 0.000 description 2
- 239000002245 particle Substances 0.000 description 2
- 230000035515 penetration Effects 0.000 description 2
- 108090000623 proteins and genes Proteins 0.000 description 2
- 230000005855 radiation Effects 0.000 description 2
- 230000008929 regeneration Effects 0.000 description 2
- 238000011069 regeneration method Methods 0.000 description 2
- 230000037387 scars Effects 0.000 description 2
- 230000001953 sensory effect Effects 0.000 description 2
- 229910052710 silicon Inorganic materials 0.000 description 2
- 239000010703 silicon Substances 0.000 description 2
- 210000002027 skeletal muscle Anatomy 0.000 description 2
- 206010040882 skin lesion Diseases 0.000 description 2
- 231100000444 skin lesion Toxicity 0.000 description 2
- 230000004936 stimulating effect Effects 0.000 description 2
- 210000004304 subcutaneous tissue Anatomy 0.000 description 2
- 238000004381 surface treatment Methods 0.000 description 2
- 230000001225 therapeutic effect Effects 0.000 description 2
- 238000013334 tissue model Methods 0.000 description 2
- 239000003053 toxin Substances 0.000 description 2
- 231100000765 toxin Toxicity 0.000 description 2
- 108700012359 toxins Proteins 0.000 description 2
- 238000011277 treatment modality Methods 0.000 description 2
- OFNXOACBUMGOPC-HZYVHMACSA-N 5'-hydroxystreptomycin Chemical compound CN[C@H]1[C@H](O)[C@@H](O)[C@H](CO)O[C@H]1O[C@@H]1[C@](C=O)(O)[C@H](CO)O[C@H]1O[C@@H]1[C@@H](NC(N)=N)[C@H](O)[C@@H](NC(N)=N)[C@H](O)[C@H]1O OFNXOACBUMGOPC-HZYVHMACSA-N 0.000 description 1
- 206010002091 Anaesthesia Diseases 0.000 description 1
- 206010003658 Atrial Fibrillation Diseases 0.000 description 1
- 206010003694 Atrophy Diseases 0.000 description 1
- 208000000094 Chronic Pain Diseases 0.000 description 1
- RYGMFSIKBFXOCR-UHFFFAOYSA-N Copper Chemical compound [Cu] RYGMFSIKBFXOCR-UHFFFAOYSA-N 0.000 description 1
- 206010063560 Excessive granulation tissue Diseases 0.000 description 1
- 206010016326 Feeling cold Diseases 0.000 description 1
- 206010016654 Fibrosis Diseases 0.000 description 1
- 241001465754 Metazoa Species 0.000 description 1
- 208000008238 Muscle Spasticity Diseases 0.000 description 1
- 208000029549 Muscle injury Diseases 0.000 description 1
- 241000158526 Nasalis Species 0.000 description 1
- 206010030113 Oedema Diseases 0.000 description 1
- 108010081750 Reticulin Proteins 0.000 description 1
- 239000004809 Teflon Substances 0.000 description 1
- 229920006362 Teflon® Polymers 0.000 description 1
- 108010057266 Type A Botulinum Toxins Proteins 0.000 description 1
- 230000003213 activating effect Effects 0.000 description 1
- 230000006978 adaptation Effects 0.000 description 1
- 210000001789 adipocyte Anatomy 0.000 description 1
- 230000002411 adverse Effects 0.000 description 1
- 229910052782 aluminium Inorganic materials 0.000 description 1
- XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 description 1
- 230000037005 anaesthesia Effects 0.000 description 1
- 238000004458 analytical method Methods 0.000 description 1
- 210000003484 anatomy Anatomy 0.000 description 1
- 238000003491 array Methods 0.000 description 1
- 230000037444 atrophy Effects 0.000 description 1
- 230000004323 axial length Effects 0.000 description 1
- 230000003376 axonal effect Effects 0.000 description 1
- 229940094657 botulinum toxin type a Drugs 0.000 description 1
- 229910002092 carbon dioxide Inorganic materials 0.000 description 1
- 239000001569 carbon dioxide Substances 0.000 description 1
- 210000000845 cartilage Anatomy 0.000 description 1
- 230000032823 cell division Effects 0.000 description 1
- 210000000170 cell membrane Anatomy 0.000 description 1
- 239000013043 chemical agent Substances 0.000 description 1
- 230000000973 chemotherapeutic effect Effects 0.000 description 1
- 230000010428 chromatin condensation Effects 0.000 description 1
- 238000007906 compression Methods 0.000 description 1
- 230000006835 compression Effects 0.000 description 1
- 239000006258 conductive agent Substances 0.000 description 1
- 229910052802 copper Inorganic materials 0.000 description 1
- 239000010949 copper Substances 0.000 description 1
- 238000012937 correction Methods 0.000 description 1
- 238000002316 cosmetic surgery Methods 0.000 description 1
- 230000034994 death Effects 0.000 description 1
- 230000003247 decreasing effect Effects 0.000 description 1
- 230000001419 dependent effect Effects 0.000 description 1
- 238000013461 design Methods 0.000 description 1
- 230000004069 differentiation Effects 0.000 description 1
- 238000002845 discoloration Methods 0.000 description 1
- 238000009826 distribution Methods 0.000 description 1
- 230000002828 effect on organs or tissue Effects 0.000 description 1
- 230000007613 environmental effect Effects 0.000 description 1
- 210000004709 eyebrow Anatomy 0.000 description 1
- 230000001815 facial effect Effects 0.000 description 1
- 239000000835 fiber Substances 0.000 description 1
- 210000002950 fibroblast Anatomy 0.000 description 1
- 230000003328 fibroblastic effect Effects 0.000 description 1
- 230000004761 fibrosis Effects 0.000 description 1
- 239000000945 filler Substances 0.000 description 1
- NBVXSUQYWXRMNV-UHFFFAOYSA-N fluoromethane Chemical compound FC NBVXSUQYWXRMNV-UHFFFAOYSA-N 0.000 description 1
- 210000001061 forehead Anatomy 0.000 description 1
- 238000013467 fragmentation Methods 0.000 description 1
- 238000006062 fragmentation reaction Methods 0.000 description 1
- 238000007710 freezing Methods 0.000 description 1
- 230000008014 freezing Effects 0.000 description 1
- 210000001126 granulation tissue Anatomy 0.000 description 1
- 230000001632 homeopathic effect Effects 0.000 description 1
- OFNXOACBUMGOPC-UHFFFAOYSA-N hydroxystreptomycin Natural products CNC1C(O)C(O)C(CO)OC1OC1C(C=O)(O)C(CO)OC1OC1C(N=C(N)N)C(O)C(N=C(N)N)C(O)C1O OFNXOACBUMGOPC-UHFFFAOYSA-N 0.000 description 1
- 239000012642 immune effector Substances 0.000 description 1
- 229940121354 immunomodulator Drugs 0.000 description 1
- 230000001771 impaired effect Effects 0.000 description 1
- 239000007943 implant Substances 0.000 description 1
- 230000000415 inactivating effect Effects 0.000 description 1
- 239000000411 inducer Substances 0.000 description 1
- 230000006882 induction of apoptosis Effects 0.000 description 1
- 210000004969 inflammatory cell Anatomy 0.000 description 1
- 239000003112 inhibitor Substances 0.000 description 1
- 230000030214 innervation Effects 0.000 description 1
- 239000011810 insulating material Substances 0.000 description 1
- 230000001788 irregular Effects 0.000 description 1
- 238000002955 isolation Methods 0.000 description 1
- OKPOKMCPHKVCPP-UHFFFAOYSA-N isoorientaline Natural products C1=C(O)C(OC)=CC(CC2C3=CC(OC)=C(O)C=C3CCN2C)=C1 OKPOKMCPHKVCPP-UHFFFAOYSA-N 0.000 description 1
- 238000002690 local anesthesia Methods 0.000 description 1
- 210000001352 masseter muscle Anatomy 0.000 description 1
- 230000035800 maturation Effects 0.000 description 1
- 230000006371 metabolic abnormality Effects 0.000 description 1
- 229910052751 metal Inorganic materials 0.000 description 1
- 239000002184 metal Substances 0.000 description 1
- 150000002739 metals Chemical class 0.000 description 1
- 230000000116 mitigating effect Effects 0.000 description 1
- 230000001483 mobilizing effect Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 230000004660 morphological change Effects 0.000 description 1
- 210000001611 motor endplate Anatomy 0.000 description 1
- 210000003007 myelin sheath Anatomy 0.000 description 1
- 210000000651 myofibroblast Anatomy 0.000 description 1
- 210000001640 nerve ending Anatomy 0.000 description 1
- 230000007383 nerve stimulation Effects 0.000 description 1
- 230000002232 neuromuscular Effects 0.000 description 1
- 230000009689 neuronal regeneration Effects 0.000 description 1
- 239000001272 nitrous oxide Substances 0.000 description 1
- 231100001160 nonlethal Toxicity 0.000 description 1
- 230000003287 optical effect Effects 0.000 description 1
- 230000036407 pain Effects 0.000 description 1
- 230000008058 pain sensation Effects 0.000 description 1
- 230000010412 perfusion Effects 0.000 description 1
- 230000000144 pharmacologic effect Effects 0.000 description 1
- 230000000704 physical effect Effects 0.000 description 1
- 230000001766 physiological effect Effects 0.000 description 1
- 229920001296 polysiloxane Polymers 0.000 description 1
- 229920001343 polytetrafluoroethylene Polymers 0.000 description 1
- 239000004810 polytetrafluoroethylene Substances 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 238000012545 processing Methods 0.000 description 1
- 230000035755 proliferation Effects 0.000 description 1
- 210000002176 pterygoid muscle Anatomy 0.000 description 1
- 238000011084 recovery Methods 0.000 description 1
- 230000011514 reflex Effects 0.000 description 1
- 230000003716 rejuvenation Effects 0.000 description 1
- JTQHYPFKHZLTSH-UHFFFAOYSA-N reticulin Natural products COC1CC(OC2C(CO)OC(OC3C(O)CC(OC4C(C)OC(CC4OC)OC5CCC6(C)C7CCC8(C)C(CCC8(O)C7CC=C6C5)C(C)O)OC3C)C(O)C2OC)OC(C)C1O JTQHYPFKHZLTSH-UHFFFAOYSA-N 0.000 description 1
- 210000004116 schwann cell Anatomy 0.000 description 1
- 230000035807 sensation Effects 0.000 description 1
- 230000008054 signal transmission Effects 0.000 description 1
- 210000000419 skeletal muscle satellite cell Anatomy 0.000 description 1
- 239000011780 sodium chloride Substances 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 239000002904 solvent Substances 0.000 description 1
- 208000018198 spasticity Diseases 0.000 description 1
- 210000004003 subcutaneous fat Anatomy 0.000 description 1
- 239000000758 substrate Substances 0.000 description 1
- 230000004083 survival effect Effects 0.000 description 1
- 230000008685 targeting Effects 0.000 description 1
- 210000000966 temporal muscle Anatomy 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
- 230000000451 tissue damage Effects 0.000 description 1
- 231100000827 tissue damage Toxicity 0.000 description 1
- 230000008467 tissue growth Effects 0.000 description 1
- 231100000167 toxic agent Toxicity 0.000 description 1
- 239000003440 toxic substance Substances 0.000 description 1
- 238000011269 treatment regimen Methods 0.000 description 1
- 238000002604 ultrasonography Methods 0.000 description 1
- 210000004509 vascular smooth muscle cell Anatomy 0.000 description 1
- 230000024883 vasodilation Effects 0.000 description 1
- 230000007332 vesicle formation Effects 0.000 description 1
- 231100000009 visible necrosis Toxicity 0.000 description 1
- 230000000007 visual effect Effects 0.000 description 1
- 239000011782 vitamin Substances 0.000 description 1
- 229940088594 vitamin Drugs 0.000 description 1
- 229930003231 vitamin Natural products 0.000 description 1
- 235000013343 vitamin Nutrition 0.000 description 1
- 238000010792 warming Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B18/02—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by cooling, e.g. cryogenic techniques
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B18/04—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
- A61B18/12—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
- A61B18/14—Probes or electrodes therefor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B2017/00743—Type of operation; Specification of treatment sites
- A61B2017/00747—Dermatology
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B2017/00743—Type of operation; Specification of treatment sites
- A61B2017/00792—Plastic surgery
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00005—Cooling or heating of the probe or tissue immediately surrounding the probe
- A61B2018/00011—Cooling or heating of the probe or tissue immediately surrounding the probe with fluids
- A61B2018/00023—Cooling or heating of the probe or tissue immediately surrounding the probe with fluids closed, i.e. without wound contact by the fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00005—Cooling or heating of the probe or tissue immediately surrounding the probe
- A61B2018/00011—Cooling or heating of the probe or tissue immediately surrounding the probe with fluids
- A61B2018/00029—Cooling or heating of the probe or tissue immediately surrounding the probe with fluids open
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00005—Cooling or heating of the probe or tissue immediately surrounding the probe
- A61B2018/00041—Heating, e.g. defrosting
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00315—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for treatment of particular body parts
- A61B2018/00434—Neural system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00315—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for treatment of particular body parts
- A61B2018/00452—Skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00315—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for treatment of particular body parts
- A61B2018/00452—Skin
- A61B2018/00458—Deeper parts of the skin, e.g. treatment of vascular disorders or port wine stains
- A61B2018/00464—Subcutaneous fat, e.g. liposuction, lipolysis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B18/02—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by cooling, e.g. cryogenic techniques
- A61B2018/0231—Characteristics of handpieces or probes
- A61B2018/0237—Characteristics of handpieces or probes with a thermoelectric element in the probe for cooling purposes
- A61B2018/0243—Characteristics of handpieces or probes with a thermoelectric element in the probe for cooling purposes cooling of the hot side of the junction, e.g. heat sink
- A61B2018/025—Characteristics of handpieces or probes with a thermoelectric element in the probe for cooling purposes cooling of the hot side of the junction, e.g. heat sink by circulating liquid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B18/02—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by cooling, e.g. cryogenic techniques
- A61B2018/0231—Characteristics of handpieces or probes
- A61B2018/0262—Characteristics of handpieces or probes using a circulating cryogenic fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B18/02—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by cooling, e.g. cryogenic techniques
- A61B2018/0293—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by cooling, e.g. cryogenic techniques using an instrument interstitially inserted into the body, e.g. needle
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
- A61M2037/0023—Drug applicators using microneedles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
- A61M2037/003—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles having a lumen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/44—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests having means for cooling or heating the devices or media
Landscapes
- Health & Medical Sciences (AREA)
- Surgery (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Heart & Thoracic Surgery (AREA)
- Medical Informatics (AREA)
- Biomedical Technology (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Otolaryngology (AREA)
- Dermatology (AREA)
- Anesthesiology (AREA)
- Hematology (AREA)
- Surgical Instruments (AREA)
- Thermotherapy And Cooling Therapy Devices (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US68339305P | 2005-05-20 | 2005-05-20 | |
| US683393P | 2005-05-20 | ||
| US295204 | 2005-12-05 | ||
| US11/295,204 US7713266B2 (en) | 2005-05-20 | 2005-12-05 | Subdermal cryogenic remodeling of muscles, nerves, connective tissue, and/or adipose tissue (fat) |
| PCT/US2006/019471 WO2006127467A2 (en) | 2005-05-20 | 2006-05-18 | Subdermal cryogenic remodeling |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2389945T3 true ES2389945T3 (es) | 2012-11-05 |
Family
ID=38980777
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES06770671T Active ES2389945T3 (es) | 2005-05-20 | 2006-05-18 | Remodelación criogénica subdérmica de músculos, nervios, tejido conectivo, y/o tejido adiposo (grasa) |
Country Status (6)
| Country | Link |
|---|---|
| US (6) | US7713266B2 (cg-RX-API-DMAC7.html) |
| EP (2) | EP2499984B1 (cg-RX-API-DMAC7.html) |
| JP (1) | JP5044546B2 (cg-RX-API-DMAC7.html) |
| CA (1) | CA2608783A1 (cg-RX-API-DMAC7.html) |
| ES (1) | ES2389945T3 (cg-RX-API-DMAC7.html) |
| WO (1) | WO2006127467A2 (cg-RX-API-DMAC7.html) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10610280B1 (en) | 2019-02-02 | 2020-04-07 | Ayad K. M. Agha | Surgical method and apparatus for destruction and removal of intraperitoneal, visceral, and subcutaneous fat |
Families Citing this family (169)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2478887C (en) * | 2002-03-15 | 2013-08-13 | The General Hospital Corporation | Methods and devices for selective disruption of fatty tissue by controlled cooling |
| US8840608B2 (en) | 2002-03-15 | 2014-09-23 | The General Hospital Corporation | Methods and devices for selective disruption of fatty tissue by controlled cooling |
| US20060167445A1 (en) * | 2002-08-27 | 2006-07-27 | Gal Shafirstein | Selective conductive interstitial thermal therapy device |
| JP2006504986A (ja) * | 2002-10-15 | 2006-02-09 | ベランス・コーポレイション | メディア・モニタリング、管理および情報システム |
| US20090232755A1 (en) * | 2003-07-28 | 2009-09-17 | Leslie Baumann | Combination therapies for treating photodamaged skin |
| CA2579145C (en) | 2004-04-01 | 2023-06-27 | The General Hospital Corporation | Method and apparatus for dermatological treatment and tissue reshaping |
| US20060047281A1 (en) | 2004-09-01 | 2006-03-02 | Syneron Medical Ltd. | Method and system for invasive skin treatment |
| US8276590B2 (en) * | 2005-05-18 | 2012-10-02 | Cooltouch Incorporated | Thermally mediated tissue molding |
| US7713266B2 (en) | 2005-05-20 | 2010-05-11 | Myoscience, Inc. | Subdermal cryogenic remodeling of muscles, nerves, connective tissue, and/or adipose tissue (fat) |
| US7850683B2 (en) * | 2005-05-20 | 2010-12-14 | Myoscience, Inc. | Subdermal cryogenic remodeling of muscles, nerves, connective tissue, and/or adipose tissue (fat) |
| US7618429B2 (en) * | 2005-12-22 | 2009-11-17 | Spamedica International Srl | Skin rejuvination resurfacing method |
| US10799285B2 (en) * | 2005-12-22 | 2020-10-13 | Inmode Ltd. | Skin rejuvenation resurfacing device and method of use |
| US8961511B2 (en) | 2006-02-07 | 2015-02-24 | Viveve, Inc. | Vaginal remodeling device and methods |
| US7854754B2 (en) * | 2006-02-22 | 2010-12-21 | Zeltiq Aesthetics, Inc. | Cooling device for removing heat from subcutaneous lipid-rich cells |
| US20090299357A1 (en) * | 2006-04-24 | 2009-12-03 | Thomas Jefferson University | Cryoneedle and cryotheraphy system |
| US20070255362A1 (en) | 2006-04-28 | 2007-11-01 | Juniper Medical, Inc. | Cryoprotectant for use with a cooling device for improved cooling of subcutaneous lipid-rich cells |
| US20080140061A1 (en) * | 2006-09-08 | 2008-06-12 | Arbel Medical Ltd. | Method And Device For Combined Treatment |
| US9132031B2 (en) | 2006-09-26 | 2015-09-15 | Zeltiq Aesthetics, Inc. | Cooling device having a plurality of controllable cooling elements to provide a predetermined cooling profile |
| US8192474B2 (en) | 2006-09-26 | 2012-06-05 | Zeltiq Aesthetics, Inc. | Tissue treatment methods |
| US20080077201A1 (en) | 2006-09-26 | 2008-03-27 | Juniper Medical, Inc. | Cooling devices with flexible sensors |
| US8273080B2 (en) * | 2006-10-16 | 2012-09-25 | Syneron Medical Ltd. | Methods and devices for treating tissue |
| US8007493B2 (en) * | 2006-10-16 | 2011-08-30 | Syneron Medical Ltd. | Methods and devices for treating tissue |
| US20080281389A1 (en) * | 2006-10-16 | 2008-11-13 | Primaeva Medical Inc. | Methods and devices for treating tissue |
| US8133216B2 (en) | 2006-10-16 | 2012-03-13 | Syneron Medical Ltd. | Methods and devices for treating tissue |
| US8142426B2 (en) | 2006-10-16 | 2012-03-27 | Syneron Medical Ltd. | Methods and devices for treating tissue |
| US20080115509A1 (en) * | 2006-11-17 | 2008-05-22 | Gullickson Adam L | Methods and Apparatus for Forming and Connecting Cryoprobes for use with Cryosurgical Treatment Systems |
| US20080119839A1 (en) * | 2006-11-21 | 2008-05-22 | Vancelette David W | Cryosurgical Applicator |
| US9254162B2 (en) * | 2006-12-21 | 2016-02-09 | Myoscience, Inc. | Dermal and transdermal cryogenic microprobe systems |
| US8409185B2 (en) * | 2007-02-16 | 2013-04-02 | Myoscience, Inc. | Replaceable and/or easily removable needle systems for dermal and transdermal cryogenic remodeling |
| WO2008116232A1 (en) * | 2007-03-22 | 2008-09-25 | Alan David Widgerow | Apparatus for use in methods of cosmetic surgery and to such methods |
| US20080287839A1 (en) | 2007-05-18 | 2008-11-20 | Juniper Medical, Inc. | Method of enhanced removal of heat from subcutaneous lipid-rich cells and treatment apparatus having an actuator |
| US20090036958A1 (en) * | 2007-08-01 | 2009-02-05 | Primaeva Medical, Inc. | Methods and devices for treating tissue |
| US8845630B2 (en) * | 2007-06-15 | 2014-09-30 | Syneron Medical Ltd | Devices and methods for percutaneous energy delivery |
| US20080312647A1 (en) * | 2007-06-15 | 2008-12-18 | Primaeva Medical, Inc. | Methods and devices for treating tissue |
| JP2010533054A (ja) * | 2007-07-13 | 2010-10-21 | ゼルティック エステティックス インコーポレイテッド | 脂質リッチ領域を処置するシステム |
| US8523927B2 (en) | 2007-07-13 | 2013-09-03 | Zeltiq Aesthetics, Inc. | System for treating lipid-rich regions |
| WO2009018546A1 (en) | 2007-08-02 | 2009-02-05 | Medicis Pharmaceutical Corporation | Method of applying an injectable filler |
| EP3488833B1 (en) | 2007-08-21 | 2025-10-22 | Zeltiq Aesthetics, Inc. | Monitoring the cooling of subcutaneous lipid-rich cells, such as the cooling of adipose tissue |
| US20090112205A1 (en) * | 2007-10-31 | 2009-04-30 | Primaeva Medical, Inc. | Cartridge electrode device |
| WO2009065061A1 (en) * | 2007-11-14 | 2009-05-22 | Myoscience, Inc. | Pain management using cryogenic remodeling |
| US20090156958A1 (en) * | 2007-12-12 | 2009-06-18 | Mehta Bankim H | Devices and methods for percutaneous energy delivery |
| MX2010007860A (es) | 2008-01-17 | 2010-11-30 | Syneron Medical Ltd | Un aparato de eliminacion de vello para uso personal y metodo para usarlo. |
| KR20100115748A (ko) | 2008-01-24 | 2010-10-28 | 시네론 메디컬 리미티드 | 지방 조직 치료 장치, 기기, 및 방법 |
| WO2009111793A2 (en) * | 2008-03-07 | 2009-09-11 | Myoscience, Inc. | Subdermal tissue remodeling using myostatin, methods and related systems |
| EP2265227A4 (en) * | 2008-04-01 | 2013-08-07 | Gen Hospital Corp | PROCESS AND DEVICE FOR COOLING BIOLOGICAL TISSUE |
| US9066738B2 (en) * | 2008-07-14 | 2015-06-30 | Syneron Medical Ltd. | Devices and methods for percutaneous energy delivery |
| JP2011530349A (ja) * | 2008-08-07 | 2011-12-22 | ザ ジェネラル ホスピタル コーポレーション | 皮膚低色素沈着のための方法および装置 |
| US8512715B2 (en) | 2008-08-14 | 2013-08-20 | The Cleveland Clinic Foundation | Apparatus and method for treating a neuromuscular defect |
| US9204925B2 (en) * | 2008-08-14 | 2015-12-08 | The Cleveland Clinic Foundation | Apparatus and method for treating a neuromuscular defect |
| EP2591745B1 (en) | 2008-09-21 | 2015-01-21 | Syneron Medical Ltd. | Apparatus for personal skin treatment |
| US8275442B2 (en) | 2008-09-25 | 2012-09-25 | Zeltiq Aesthetics, Inc. | Treatment planning systems and methods for body contouring applications |
| US8603073B2 (en) | 2008-12-17 | 2013-12-10 | Zeltiq Aesthetics, Inc. | Systems and methods with interrupt/resume capabilities for treating subcutaneous lipid-rich cells |
| EP2373240B1 (en) * | 2008-12-22 | 2015-04-29 | Myoscience, Inc. | Skin protection for subdermal cryogenic remodeling for cosmetic and other treatments |
| EP2373239B1 (en) * | 2008-12-22 | 2013-08-14 | Myoscience, Inc. | Integrated cryosurgical system with refrigerant and electrical power source |
| US20100211055A1 (en) * | 2009-02-18 | 2010-08-19 | Shimon Eckhouse | Method for body toning and an integrated data management system for the same |
| EP2401026B1 (en) | 2009-02-25 | 2014-04-02 | Syneron Medical Ltd. | Electrical skin rejuvenation |
| US20100217254A1 (en) * | 2009-02-25 | 2010-08-26 | Primaeva Medical, Inc. | Methods for applying energy to tissue using isolated energy sources |
| US20120022510A1 (en) * | 2009-03-05 | 2012-01-26 | Cynosure, Inc. | Thermal surgery safety apparatus and method |
| GB2481760B (en) * | 2009-04-30 | 2014-01-29 | Alma Lasers Ltd | Devices for dermatological treatment |
| CA2760610C (en) | 2009-04-30 | 2017-09-19 | Zeltiq Aesthetics, Inc. | Device, system and method of removing heat from subcutaneous lipid-rich cells |
| RU2012107673A (ru) | 2009-08-04 | 2013-09-10 | Поллоген Лтд. | Косметическое омоложение кожи |
| HRP20160069T1 (hr) * | 2009-09-18 | 2016-02-26 | Viveve Inc. | Uređaj za vaginalno remodeliranje |
| US11590346B2 (en) | 2009-11-16 | 2023-02-28 | Pollogen Ltd. | Apparatus and method for cosmetic treatment of human mucosal tissue |
| CN103068355A (zh) | 2009-11-16 | 2013-04-24 | 抛罗根有限公司 | 非侵入性的脂肪去除 |
| WO2011091431A1 (en) | 2010-01-25 | 2011-07-28 | Zeltiq Aesthetics, Inc. | Home-use applicators for non-invasively removing heat from subcutaneous lipid-rich cells via phase change coolants, and associated devices, systems and methods |
| WO2011100692A1 (en) | 2010-02-15 | 2011-08-18 | The General Hospital Corporation | Methods and devices for selective disruption of visceral fat by controlled cooling |
| US8676338B2 (en) | 2010-07-20 | 2014-03-18 | Zeltiq Aesthetics, Inc. | Combined modality treatment systems, methods and apparatus for body contouring applications |
| GB2483505B (en) * | 2010-09-13 | 2012-10-10 | Ndm Technologies Ltd | Devices for transdermal drug delivery |
| BR112013014728A2 (pt) * | 2010-12-13 | 2016-10-04 | Myoscience Inc | método de redução de rugas faciais hiperdinâmicas |
| US10722395B2 (en) | 2011-01-25 | 2020-07-28 | Zeltiq Aesthetics, Inc. | Devices, application systems and methods with localized heat flux zones for removing heat from subcutaneous lipid-rich cells |
| US9078634B2 (en) | 2011-01-27 | 2015-07-14 | Cryosa, Llc | Apparatus and methods for treatment of obstructive sleep apnea utilizing cryolysis of adipose tissues |
| US20120271219A1 (en) * | 2011-04-19 | 2012-10-25 | David John Weisgerber | Combined Energy and Topical Composition Application For Regulating the Condition of Mammalian Skin |
| KR102081868B1 (ko) * | 2011-06-28 | 2020-02-26 | 이노비오 파마수티컬즈, 인크. | 최소 침습 피부 전기천공 장치 |
| CN104667420B (zh) * | 2011-09-13 | 2017-09-08 | Ndm科技有限公司 | 透皮药物输送装置 |
| EP2773276B1 (en) * | 2011-11-05 | 2018-04-04 | Medtronic Ardian Luxembourg S.à.r.l. | Systems for crynogenic renal neuromodulation |
| CN109602489A (zh) | 2011-11-16 | 2019-04-12 | 通用医疗公司 | 用于低温处理皮肤组织的方法和装置 |
| EP3766445A1 (en) | 2011-11-16 | 2021-01-20 | The General Hospital Corporation | Method and apparatus for cryogenic treatment of skin tissue |
| WO2013106857A1 (en) | 2012-01-13 | 2013-07-18 | Myoscience, Inc. | Skin protection for subdermal cryogenic remodeling for cosmetic and other treatments |
| EP2802279B1 (en) | 2012-01-13 | 2017-08-16 | Myoscience, Inc. | Cryogenic needle with freeze zone regulation |
| CN104159534B (zh) * | 2012-01-13 | 2017-02-22 | 肌肉科技股份有限公司 | 用于美容和其他处理的皮下低温重塑的皮肤保护 |
| CA2861116A1 (en) * | 2012-01-13 | 2013-07-18 | Myoscience, Inc. | Cryogenic probe filtration system |
| US9017318B2 (en) | 2012-01-20 | 2015-04-28 | Myoscience, Inc. | Cryogenic probe system and method |
| CN105919666A (zh) | 2012-03-16 | 2016-09-07 | 女康乐公司 | 一种修复女性阴道组织的治疗器 |
| US9844460B2 (en) | 2013-03-14 | 2017-12-19 | Zeltiq Aesthetics, Inc. | Treatment systems with fluid mixing systems and fluid-cooled applicators and methods of using the same |
| US9545523B2 (en) | 2013-03-14 | 2017-01-17 | Zeltiq Aesthetics, Inc. | Multi-modality treatment systems, methods and apparatus for altering subcutaneous lipid-rich tissue |
| US20140350536A1 (en) | 2013-03-15 | 2014-11-27 | Myoscience, Inc. | Cryogenic Blunt Dissection Methods and Devices |
| US9295512B2 (en) | 2013-03-15 | 2016-03-29 | Myoscience, Inc. | Methods and devices for pain management |
| US9610112B2 (en) * | 2013-03-15 | 2017-04-04 | Myoscience, Inc. | Cryogenic enhancement of joint function, alleviation of joint stiffness and/or alleviation of pain associated with osteoarthritis |
| US20140276359A1 (en) * | 2013-03-15 | 2014-09-18 | Plum Systems Co. | Apparatus and method for tissue rejuvenation |
| US9668800B2 (en) | 2013-03-15 | 2017-06-06 | Myoscience, Inc. | Methods and systems for treatment of spasticity |
| US9522230B2 (en) * | 2013-04-10 | 2016-12-20 | BioMime Innovations, LLC | Mechanical leech system |
| EP3065658B1 (en) | 2013-11-05 | 2021-03-31 | Pacira CryoTech, Inc. | Secure cryosurgical treatment system |
| EP3099261A2 (en) | 2014-01-31 | 2016-12-07 | Zeltiq Aesthetics, Inc. | Treating systems for treating cellulite by cooling |
| US10675176B1 (en) | 2014-03-19 | 2020-06-09 | Zeltiq Aesthetics, Inc. | Treatment systems, devices, and methods for cooling targeted tissue |
| USD777338S1 (en) | 2014-03-20 | 2017-01-24 | Zeltiq Aesthetics, Inc. | Cryotherapy applicator for cooling tissue |
| US10952891B1 (en) | 2014-05-13 | 2021-03-23 | Zeltiq Aesthetics, Inc. | Treatment systems with adjustable gap applicators and methods for cooling tissue |
| JPWO2016006409A1 (ja) * | 2014-07-09 | 2017-04-27 | 凸版印刷株式会社 | 液剤注入装置 |
| US10568759B2 (en) | 2014-08-19 | 2020-02-25 | Zeltiq Aesthetics, Inc. | Treatment systems, small volume applicators, and methods for treating submental tissue |
| US10935174B2 (en) | 2014-08-19 | 2021-03-02 | Zeltiq Aesthetics, Inc. | Stress relief couplings for cryotherapy apparatuses |
| JP6858698B2 (ja) | 2014-08-28 | 2021-04-21 | ザ ジェネラル ホスピタル コーポレイション | 注射可能なスラリーならびにその製造方法および使用方法 |
| US11504322B2 (en) | 2014-08-28 | 2022-11-22 | The General Hospital Corporation | Injectable slurries and methods of manufacturing the same |
| CA2962920C (en) | 2014-10-01 | 2023-03-14 | Cryosa, Llc | Apparatus and methods for treatment of obstructive sleep apnea utilizing cryolysis of adipose tissues |
| US10687737B2 (en) | 2015-03-10 | 2020-06-23 | Muscle Activation Techniques, Llc | Methods, systems and kits for enhanced muscle contractile capabilities |
| WO2016145452A1 (en) | 2015-03-12 | 2016-09-15 | Myoscience, Inc. | Methods and systems for preventing neuroma formations |
| US10327830B2 (en) * | 2015-04-01 | 2019-06-25 | Monteris Medical Corporation | Cryotherapy, thermal therapy, temperature modulation therapy, and probe apparatus therefor |
| EP3344176A4 (en) | 2015-09-04 | 2019-04-17 | R2 Dermatology, Inc. | SYSTEMS, METHODS AND MEDICAL DEVICES FOR COOLING HYPOPIGMENTATION TREATMENTS |
| US20170079833A1 (en) * | 2015-09-21 | 2017-03-23 | Zeltiq Aesthestics, Inc. | Transcutaneous treatment systems, cooling devices, and methods for cooling nerves |
| EP3355799B1 (en) * | 2015-09-27 | 2021-09-01 | Follica, Inc. | Needling device and drug applicator |
| WO2017070112A1 (en) | 2015-10-19 | 2017-04-27 | Zeltiq Aesthetics, Inc. | Vascular treatment systems, cooling devices, and methods for cooling vascular structures |
| KR20220098285A (ko) | 2016-01-07 | 2022-07-11 | 젤티크 애스세틱스, 인코포레이티드. | 조직의 냉각 동안 애플리케이터와 피부 사이의 온도 의존성 접착 |
| US10765552B2 (en) | 2016-02-18 | 2020-09-08 | Zeltiq Aesthetics, Inc. | Cooling cup applicators with contoured heads and liner assemblies |
| US10682297B2 (en) | 2016-05-10 | 2020-06-16 | Zeltiq Aesthetics, Inc. | Liposomes, emulsions, and methods for cryotherapy |
| US11382790B2 (en) | 2016-05-10 | 2022-07-12 | Zeltiq Aesthetics, Inc. | Skin freezing systems for treating acne and skin conditions |
| US10555831B2 (en) | 2016-05-10 | 2020-02-11 | Zeltiq Aesthetics, Inc. | Hydrogel substances and methods of cryotherapy |
| US11311327B2 (en) | 2016-05-13 | 2022-04-26 | Pacira Cryotech, Inc. | Methods and systems for locating and treating nerves with cold therapy |
| CN109310460B (zh) | 2016-06-03 | 2022-09-27 | R2科技公司 | 冷却系统和皮肤处理方法 |
| US20190183558A1 (en) * | 2016-08-30 | 2019-06-20 | The General Hospital Corporation | Cryotherapy and cryoablation systems and methods for treatment of tissue |
| EP3528730B1 (en) * | 2016-10-20 | 2025-12-03 | Old Dominion University Research Foundation | Devices for using sub-microsecond electric pulses to trigger apoptosis |
| CA3042402A1 (en) | 2016-11-02 | 2018-05-11 | Christopher J. P. Velis | Devices and methods for slurry generation |
| KR101905830B1 (ko) | 2016-11-15 | 2018-10-08 | 울산과학기술원 | 국부 냉각 마취 장치, 국부 냉각 마취 장치의 제어 방법 및 국부 냉각 마취 장치의 냉각 온도 조절기 |
| US11324673B2 (en) * | 2016-11-18 | 2022-05-10 | Miraki Innovation Think Tank Llc | Cosmetic appearance of skin |
| US11511110B2 (en) | 2018-06-27 | 2022-11-29 | Viveve, Inc. | Methods for treating urinary stress incontinence |
| US11896823B2 (en) | 2017-04-04 | 2024-02-13 | Btl Healthcare Technologies A.S. | Method and device for pelvic floor tissue treatment |
| US11446178B2 (en) | 2017-04-05 | 2022-09-20 | Miraki Innovation Think Tank Llc | Cold slurry containment |
| US11439532B2 (en) | 2017-04-05 | 2022-09-13 | Miraki Innovation Think Tank Llc | Point of delivery cold slurry generation |
| US11076879B2 (en) | 2017-04-26 | 2021-08-03 | Zeltiq Aesthetics, Inc. | Shallow surface cryotherapy applicators and related technology |
| WO2018221848A1 (ko) | 2017-05-30 | 2018-12-06 | 주식회사 리센스메디컬 | 의료용 냉각 장치 |
| KR20180131352A (ko) | 2017-05-30 | 2018-12-10 | 주식회사 리센스메디컬 | 의료용 냉각 장치 |
| JP2020526263A (ja) | 2017-06-30 | 2020-08-31 | アールツー・テクノロジーズ・インコーポレイテッド | 直線配列のノズルを有する皮膚科学的低温スプレー装置及び使用方法 |
| US10500342B2 (en) | 2017-08-21 | 2019-12-10 | Miraki Innovation Think Tank Llc | Cold slurry syringe |
| WO2019099677A1 (en) | 2017-11-15 | 2019-05-23 | Myoscience, Inc. | Integrated cold therapy and electrical stimulation systems for locating and treating nerves and associated methods |
| KR102517065B1 (ko) | 2017-12-29 | 2023-04-03 | 주식회사 리센스메디컬 | 냉각발생장치 |
| USD999392S1 (en) * | 2018-01-01 | 2023-09-19 | Rooijakkers Huisman L S | Vibrator |
| WO2019209081A1 (ko) | 2018-04-27 | 2019-10-31 | 주식회사 리센스메디컬 | 냉각장치 및 냉각방법 |
| KR102161877B1 (ko) * | 2018-04-27 | 2020-10-05 | 울산과학기술원 | 의료용 냉각장치 |
| CN112955099B (zh) | 2018-07-27 | 2024-04-26 | 雷森斯医疗有限公司 | 医疗冷却装置和使用其的冷却方法 |
| KR20210038661A (ko) | 2018-07-31 | 2021-04-07 | 젤티크 애스세틱스, 인코포레이티드. | 피부 특성을 개선시키기 위한 방법, 장치, 및 시스템 |
| US11666479B2 (en) | 2018-08-19 | 2023-06-06 | Recensmedical, Inc. | Device for cooling anesthesia by chilled fluidic cooling medium |
| US11523855B2 (en) | 2018-09-28 | 2022-12-13 | Team Neuro LLC | Spinal pain management system and method |
| KR102735829B1 (ko) | 2018-12-07 | 2024-11-29 | 주식회사 리센스메디컬 | 냉각장치 및 냉각방법 |
| JP2022514034A (ja) | 2018-12-21 | 2022-02-09 | アールツー・テクノロジーズ・インコーポレイテッド | 皮膚用クライオスプレーデバイス用の自動制御および位置決めシステム |
| KR20210107072A (ko) | 2018-12-21 | 2021-08-31 | 알2 테크놀로지스, 인크. | 자동화된 피부학적 냉동 분무 처리 계획 시스템 |
| USD921911S1 (en) | 2019-06-21 | 2021-06-08 | Recensmedical, Inc. | Medical cooling device |
| USD921211S1 (en) | 2019-06-21 | 2021-06-01 | Recensmedical, Inc. | Medical cooling device |
| TWI844708B (zh) | 2019-07-22 | 2024-06-11 | 美商布魯克斯熱傳導公司 | 熱管理系統及相關之半導體裝置 |
| US12121281B2 (en) | 2019-08-07 | 2024-10-22 | Christopher M. Shaari | Systems and methods for cryogenic treatment of headache |
| CN115038396A (zh) | 2019-10-29 | 2022-09-09 | 帕西拉冷冻技术股份有限公司 | 带有快速连接的针式探头的低温装置 |
| USD914903S1 (en) * | 2019-11-04 | 2021-03-30 | Shenzhen Boyuan Intelligent Electronic Technology Co., Ltd | Beauty instrument |
| US20220354562A1 (en) * | 2019-11-26 | 2022-11-10 | Amir Katz | Cryotherapy Skin Growth Removal Device |
| US11740759B2 (en) | 2019-11-27 | 2023-08-29 | Pacira Cryotech, Inc. | Display device and interfaces for cryogenic devices |
| JP7658967B2 (ja) | 2019-12-03 | 2025-04-08 | パシラ クライオテック インコーポレイテッド | 低温装置の圧力の安定化 |
| US11633224B2 (en) | 2020-02-10 | 2023-04-25 | Icecure Medical Ltd. | Cryogen pump |
| KR102168702B1 (ko) * | 2020-06-11 | 2020-10-22 | 주식회사 리센스메디컬 | 의료용 냉각장치 |
| US11278341B2 (en) | 2020-07-14 | 2022-03-22 | Recensmedical, Inc. | Method of safely using controlled cooling systems and devices |
| USD968626S1 (en) | 2020-08-07 | 2022-11-01 | Recensmedical, Inc. | Medical cooling device |
| USD977633S1 (en) | 2020-08-07 | 2023-02-07 | Recensmedical, Inc. | Cradle for a medical cooling device |
| USD968627S1 (en) | 2020-08-07 | 2022-11-01 | Recensmedical, Inc. | Medical cooling device |
| US11229779B1 (en) | 2020-08-12 | 2022-01-25 | Enrico Guarino | Method for skin ligament injection to obtain a lifting effect |
| USD919082S1 (en) * | 2020-08-26 | 2021-05-11 | Xianlin He | Microneedle instrument |
| US12447043B2 (en) | 2021-01-20 | 2025-10-21 | R2 Technologies, Inc. | Dermatological treatments and systems employing cooling, topicals, and/or abrasion |
| US12364531B2 (en) | 2021-02-16 | 2025-07-22 | RecensMedical, Inc.; | Methods for treating skin disorders using precision cooling technology |
| WO2022187821A1 (en) | 2021-03-01 | 2022-09-09 | Bluexthermal, Inc. | Device and method for thermal modulation of tissue |
| JP2025502801A (ja) | 2021-12-30 | 2025-01-28 | クライオサ， インク． | 閉塞性睡眠時無呼吸の治療のためのシステム及び方法 |
| US12426934B2 (en) | 2022-02-28 | 2025-09-30 | Icecure Medical Ltd. | Cryogen flow control |
| WO2023238038A1 (en) * | 2022-06-07 | 2023-12-14 | Venus Concept Inc. | Method and device for treating cellulite |
| US12048852B2 (en) * | 2022-07-05 | 2024-07-30 | StimuSIL, Inc. | Dermal light delivery device for light therapy |
| US12215811B2 (en) | 2022-07-18 | 2025-02-04 | Icecure Medical Ltd. | Cryogenic system connector |
| WO2025003171A1 (en) * | 2023-06-30 | 2025-01-02 | Merz Aesthetics Gmbh | Device for percutaneous cryolipolysis, kit for percutaneous cryolipolysis and use of such a device or kit for percutaneous cryolipolysis |
| US20250339702A1 (en) * | 2024-05-02 | 2025-11-06 | BiLLite Medical LLC | Devices, Systems, and Methods for Application of Radio Frequency Energy to Sub-Cutaneous Tissue |
Family Cites Families (215)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2319542A (en) | 1940-06-24 | 1943-05-18 | Franklin E Hall | Therapeutic machine |
| US2672032A (en) | 1951-10-19 | 1954-03-16 | Towse Robert Albert Edward | Carcass freezing device |
| US3226492A (en) | 1961-06-30 | 1965-12-28 | Ericsson Telefon Ab L M | Circuit arrangement for telephone instruments |
| US3289424A (en) | 1963-07-01 | 1966-12-06 | Union Carbide Corp | Cryosurgical fluid control system |
| US3266492A (en) | 1963-09-06 | 1966-08-16 | Samuel B Steinberg | Cryosurgery probe device |
| US3351063A (en) | 1964-12-08 | 1967-11-07 | Stephen F Malaker | Cryosurgical probe |
| US3439680A (en) | 1965-04-12 | 1969-04-22 | Univ Northwestern | Surgical instrument for cataract removal |
| BE678971A (cg-RX-API-DMAC7.html) * | 1965-04-13 | 1966-09-16 | ||
| US3343544A (en) | 1965-12-21 | 1967-09-26 | Alcon Lab Inc | Cryogenic surgical instrument |
| GB1103079A (en) * | 1966-02-17 | 1968-02-14 | Internat Res And Dev Company L | Improvements in and relating to surgical probes |
| US3532094A (en) | 1967-07-20 | 1970-10-06 | Norman O Stahl | Cryogenic-instrument with detachable probe |
| US3507283A (en) | 1967-10-11 | 1970-04-21 | Univ Northwestern | Cryosurgical instrument |
| US3702114A (en) | 1970-08-26 | 1972-11-07 | Frigitronics Of Conn Inc | Liquid refrigerant spray device |
| US3664344A (en) | 1970-09-15 | 1972-05-23 | Brymill Corp | Tyned cryosurgical probe |
| US3795245A (en) | 1971-04-29 | 1974-03-05 | Al Co Du | Splash-proof leak-proof syringe-type cryosurgical instrument |
| GB1360353A (en) | 1972-01-19 | 1974-07-17 | Atomic Energy Authority Uk | Method of making thermocouples |
| GB1402632A (en) | 1972-02-02 | 1975-08-13 | Wilkinson Sword Ltd | Medical equipment |
| US3814095A (en) | 1972-03-24 | 1974-06-04 | H Lubens | Occlusively applied anesthetic patch |
| US3886945A (en) | 1972-06-14 | 1975-06-03 | Frigitronics Of Conn Inc | Cryosurgical apparatus |
| US3830239A (en) | 1972-09-12 | 1974-08-20 | Frigitronics Of Conn Inc | Cryosurgical device |
| US3827436A (en) | 1972-11-10 | 1974-08-06 | Frigitronics Of Conn Inc | Multipurpose cryosurgical probe |
| US3951152A (en) | 1974-06-03 | 1976-04-20 | Dynatech Corporation | Cryosurgical probe |
| US3910278A (en) * | 1974-06-03 | 1975-10-07 | Dynatech Corp | Cryosurgical probe |
| US3889681A (en) | 1974-10-30 | 1975-06-17 | Jack Douglas Waller | Cryosurgical spraying apparatus |
| US3993075A (en) | 1975-12-24 | 1976-11-23 | Dynatech Corporation | Disposable, defrostable cryosurgical probe |
| GB1534162A (en) * | 1976-07-21 | 1978-11-29 | Lloyd J | Cyosurgical probe |
| US4140109A (en) | 1977-10-17 | 1979-02-20 | Savic Michael I | Impedance-based method and apparatus for monitoring cryodestruction in controlled cryosurgery |
| US4236518A (en) | 1978-04-14 | 1980-12-02 | Gyne-Tech Instrument Corporation | Cryogenic device selectively operable in a continuous freezing mode, a continuous thawing mode or a combination thereof |
| US4306568A (en) | 1979-12-04 | 1981-12-22 | Torre Douglas P | Method and apparatus for congelation cryometry in cryosurgery |
| US4376376A (en) | 1980-05-12 | 1983-03-15 | Virginia M. Gregory | Cryogenic device operable in single or dual phase with a range of nozzle sizes and method of using the same |
| DE3022216A1 (de) | 1980-06-13 | 1982-01-28 | Heinz 3012 Langenhagen Hennecke | Tieftemperaturuebertragungseinrichtung fuer medizinische zwecke |
| US4404862A (en) | 1981-11-02 | 1983-09-20 | Dynatech Precision Sampling Corporation | Microdispensing springs with a needle in a tubular extension |
| JPS6013111Y2 (ja) | 1981-11-26 | 1985-04-26 | 株式会社ケンウッド | 電子機器 |
| US4524771A (en) | 1982-10-28 | 1985-06-25 | Ethicon Inc. | Multiple curved surgical needle |
| JPS6013111A (ja) | 1983-06-30 | 1985-01-23 | Oyo Suiken Kk | ２重管式変圧定量注水方法 |
| GB2190842B (en) | 1986-05-05 | 1990-03-07 | Oreal | Apparatus for the cryogenic treatment of the skin |
| US4802475A (en) | 1987-06-22 | 1989-02-07 | Weshahy Ahmed H A G | Methods and apparatus of applying intra-lesional cryotherapy |
| JPH0538347Y2 (cg-RX-API-DMAC7.html) | 1987-10-28 | 1993-09-28 | ||
| GB2230191B (en) | 1989-04-15 | 1992-04-22 | Robert Graham Urie | Lesion location device |
| US4946460A (en) | 1989-04-26 | 1990-08-07 | Cryo Instruments, Inc. | Apparatus for cryosurgery |
| US5200170A (en) | 1989-07-18 | 1993-04-06 | Mcdow Ronald A | Medical process--use of dichlorodifluoromethane (CCl2 F2) and chlorodifluoromethane (CHClF2) as cryogens for treating skin lesions |
| ZA917281B (en) | 1990-09-26 | 1992-08-26 | Cryomedical Sciences Inc | Cryosurgical instrument and system and method of cryosurgery |
| JP3142008B2 (ja) | 1991-06-03 | 2001-03-07 | 株式会社前川製作所 | 生体凍結用治療針 |
| JPH0538347A (ja) | 1991-08-06 | 1993-02-19 | Mayekawa Mfg Co Ltd | 生体組織凍結装置 |
| US7549424B2 (en) | 1991-10-18 | 2009-06-23 | Pro Surg, Inc. | Method and apparatus for tissue treatment with laser and electromagnetic radiation |
| US5281215A (en) | 1992-04-16 | 1994-01-25 | Implemed, Inc. | Cryogenic catheter |
| WO1993021840A1 (en) | 1992-04-24 | 1993-11-11 | Surgical Laser Technologies | Thermally-resistant medical probe |
| US5294325A (en) | 1992-07-09 | 1994-03-15 | World Precision Instruments, Inc. | Miniaturized fluid conveying device and methods of use thereof |
| DE4322955B4 (de) | 1992-07-20 | 2007-12-20 | Aesculap Ag & Co. Kg | Invasives chirurgisches Instrument |
| US5334147A (en) * | 1993-04-28 | 1994-08-02 | Cordis Corporation | Rapid exchange type dilatation catheter |
| US5571147A (en) | 1993-11-02 | 1996-11-05 | Sluijter; Menno E. | Thermal denervation of an intervertebral disc for relief of back pain |
| US5647868A (en) | 1994-02-02 | 1997-07-15 | Chinn; Douglas Owen | Cryosurgical integrated control and monitoring system and method |
| US5536249A (en) | 1994-03-09 | 1996-07-16 | Visionary Medical Products, Inc. | Pen-type injector with a microprocessor and blood characteristic monitor |
| JP3263275B2 (ja) | 1994-04-05 | 2002-03-04 | ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア | 生体組織のレーザー処理のための装置並びに火焔状斑点母斑のレーザー処理装置 |
| US6277116B1 (en) | 1994-05-06 | 2001-08-21 | Vidaderm | Systems and methods for shrinking collagen in the dermis |
| GB2289510A (en) | 1994-05-10 | 1995-11-22 | Spembly Medical Ltd | Connector |
| GB2289414B (en) * | 1994-05-10 | 1998-05-13 | Spembly Medical Ltd | Cryosurgical instrument |
| US6290991B1 (en) | 1994-12-02 | 2001-09-18 | Quandrant Holdings Cambridge Limited | Solid dose delivery vehicle and methods of making same |
| JPH08206147A (ja) | 1995-02-06 | 1996-08-13 | Akio Usui | 発熱体及びこれを用いる貼付剤 |
| JP3283716B2 (ja) | 1995-04-07 | 2002-05-20 | シャープ株式会社 | ヒータ制御装置 |
| US5755753A (en) | 1995-05-05 | 1998-05-26 | Thermage, Inc. | Method for controlled contraction of collagen tissue |
| US7620290B2 (en) | 1995-08-31 | 2009-11-17 | Biolase Technology, Inc. | Modified-output fiber optic tips |
| FR2739557B1 (fr) | 1995-10-09 | 1997-11-14 | Cird Galderma | Utilisation d'un ligand agoniste specifique rar-gamma |
| US7189230B2 (en) * | 1996-01-05 | 2007-03-13 | Thermage, Inc. | Method for treating skin and underlying tissue |
| US20040000316A1 (en) | 1996-01-05 | 2004-01-01 | Knowlton Edward W. | Methods for creating tissue effect utilizing electromagnetic energy and a reverse thermal gradient |
| US6350276B1 (en) | 1996-01-05 | 2002-02-26 | Thermage, Inc. | Tissue remodeling apparatus containing cooling fluid |
| US6682501B1 (en) | 1996-02-23 | 2004-01-27 | Gyrus Ent, L.L.C. | Submucosal tonsillectomy apparatus and method |
| US6039730A (en) | 1996-06-24 | 2000-03-21 | Allegheny-Singer Research Institute | Method and apparatus for cryosurgery |
| JPH1014656A (ja) | 1996-07-01 | 1998-01-20 | Shigemi Kobayashi | 顔の皺取り具 |
| US5899897A (en) | 1996-09-26 | 1999-05-04 | Allegheny-Singer Research Institute | Method and apparatus for heating during cryosurgery |
| US5910104A (en) | 1996-12-26 | 1999-06-08 | Cryogen, Inc. | Cryosurgical probe with disposable sheath |
| WO1998041157A1 (en) * | 1997-03-17 | 1998-09-24 | Boris Rubinsky | Freezing method for controlled removal of fatty tissue by liposuction |
| AU6865298A (en) | 1997-03-17 | 1998-10-12 | Boris Rubinsky | The use of cryoprotective agent compounds during cryosurgery |
| US7347840B2 (en) | 2000-03-02 | 2008-03-25 | Pyng Medical Corp. | Patch for locating a target zone for penetration |
| US5976505A (en) | 1997-07-02 | 1999-11-02 | Hcs Trust | Method for cryogenically treating psoriasis with liquid nitrogen or liquid nitrous oxide |
| US6371943B1 (en) | 1997-09-08 | 2002-04-16 | Epimed International, Inc. | Spring tip needle combination |
| US5971979A (en) | 1997-12-02 | 1999-10-26 | Odyssey Technologies, Inc. | Method for cryogenic inhibition of hyperplasia |
| JP3422678B2 (ja) | 1998-01-20 | 2003-06-30 | エヌオーケー株式会社 | 差圧弁及び液体遮断弁装置 |
| US5916212A (en) | 1998-01-23 | 1999-06-29 | Cryomedical Sciences, Inc. | Hand held cyrosurgical probe system |
| US6364899B1 (en) * | 1998-01-23 | 2002-04-02 | Innercool Therapies, Inc. | Heat pipe nerve cooler |
| FR2775589B1 (fr) | 1998-03-06 | 2000-04-28 | Cryonic Medical | Appareil autonome et portable de cryogenie utilisant l'anhydride carbonique en phase liquide/solide |
| US6905494B2 (en) * | 1998-03-31 | 2005-06-14 | Innercool Therapies, Inc. | Method and device for performing cooling- or cryo-therapies for, e.g., angioplasty with reduced restenosis or pulmonary vein cell necrosis to inhibit atrial fibrillation employing tissue protection |
| US6142991A (en) * | 1998-03-31 | 2000-11-07 | Galil Medical, Ltd. | High resolution cryosurgical method and apparatus |
| US6032875A (en) * | 1998-04-21 | 2000-03-07 | Caterpillar Inc. | Lubricated heavy diesel fuel pump with precipitate build-up inhibiting features |
| US6139545A (en) | 1998-09-09 | 2000-10-31 | Vidaderm | Systems and methods for ablating discrete motor nerve regions |
| US6306119B1 (en) | 1999-01-20 | 2001-10-23 | Pearl Technology Holdings, Llc | Skin resurfacing and treatment using biocompatible materials |
| US6196839B1 (en) | 1999-01-29 | 2001-03-06 | Robert Gregg Ross | Continuous use orthodontic cooling appliance |
| US6432102B2 (en) | 1999-03-15 | 2002-08-13 | Cryovascular Systems, Inc. | Cryosurgical fluid supply |
| US6468297B1 (en) | 1999-02-24 | 2002-10-22 | Cryovascular Systems, Inc. | Cryogenically enhanced intravascular interventions |
| US7001400B1 (en) | 1999-03-04 | 2006-02-21 | Abbott Laboratories | Articulating suturing device and method |
| US6964668B2 (en) | 1999-03-04 | 2005-11-15 | Abbott Laboratories | Articulating suturing device and method |
| US7235087B2 (en) | 1999-03-04 | 2007-06-26 | Abbott Park | Articulating suturing device and method |
| US20040092964A1 (en) | 1999-03-04 | 2004-05-13 | Modesitt D. Bruce | Articulating suturing device and method |
| US6562030B1 (en) | 1999-04-06 | 2003-05-13 | Cryocath Technologies Inc. | Heater control of cryocatheter tip temperature |
| US6256533B1 (en) | 1999-06-09 | 2001-07-03 | The Procter & Gamble Company | Apparatus and method for using an intracutaneous microneedle array |
| US6277099B1 (en) | 1999-08-06 | 2001-08-21 | Becton, Dickinson And Company | Medication delivery pen |
| US20020193740A1 (en) | 1999-10-14 | 2002-12-19 | Alchas Paul G. | Method of intradermally injecting substances |
| GB2355728A (en) | 1999-10-27 | 2001-05-02 | Anson Medical Ltd | Tubular medical implants and methods of manufacture |
| JP2001178737A (ja) | 1999-12-07 | 2001-07-03 | Dieter Steinfatt | 凍結装置 |
| US6669688B2 (en) | 2000-01-25 | 2003-12-30 | The Regents Of The University Of California | Method and apparatus for measuring the heat transfer coefficient during cryogen spray cooling of tissue |
| DK1844723T3 (da) | 2000-02-03 | 2011-12-05 | Baylor College Medicine | Intraossøst nerveablationssystem |
| US6363730B1 (en) | 2000-03-15 | 2002-04-02 | The Conair Group, Inc. | Method and apparatus for cryogenic cooling |
| US6546935B2 (en) | 2000-04-27 | 2003-04-15 | Atricure, Inc. | Method for transmural ablation |
| US6494844B1 (en) * | 2000-06-21 | 2002-12-17 | Sanarus Medical, Inc. | Device for biopsy and treatment of breast tumors |
| US6503246B1 (en) | 2000-07-05 | 2003-01-07 | Mor Research Applications Ltd. | Cryoprobe and method of treating scars |
| AU2001283518A1 (en) | 2000-07-31 | 2002-02-13 | Bionix Development Corporation | Method for controlling the pain from injections or minor surgical procedures andapparatus for use therewith |
| US6905492B2 (en) | 2000-07-31 | 2005-06-14 | Galil Medical Ltd. | Planning and facilitation systems and methods for cryosurgery |
| US6840935B2 (en) | 2000-08-09 | 2005-01-11 | Bekl Corporation | Gynecological ablation procedure and system using an ablation needle |
| US6955174B2 (en) | 2000-08-18 | 2005-10-18 | Uryovascular Systems, Inc. | Cryotherapy method for detecting and treating vulnerable plaque |
| AU2001290606A1 (en) | 2000-08-31 | 2002-03-13 | Aerocomm, Inc. | System and method for transmitting information modulated radio frequency signals using infrared transmission |
| US6551309B1 (en) | 2000-09-14 | 2003-04-22 | Cryoflex, Inc. | Dual action cryoprobe and methods of using the same |
| EP1333759B1 (en) | 2000-10-16 | 2010-04-07 | Sanarus Medical, Inc. | Device for biopsy of tumors |
| US6706037B2 (en) * | 2000-10-24 | 2004-03-16 | Galil Medical Ltd. | Multiple cryoprobe apparatus and method |
| US20020068929A1 (en) | 2000-10-24 | 2002-06-06 | Roni Zvuloni | Apparatus and method for compressing a gas, and cryosurgery system and method utilizing same |
| US20040162551A1 (en) | 2000-12-15 | 2004-08-19 | Brown Tony R. | Method and device for creating transmural lesions |
| US6723092B2 (en) | 2000-12-15 | 2004-04-20 | Tony R. Brown | Atrial fibrillation RF treatment device and method |
| US7029480B2 (en) | 2001-01-24 | 2006-04-18 | Abott Laboratories | Device and method for suturing of internal puncture sites |
| US6648880B2 (en) * | 2001-02-16 | 2003-11-18 | Cryocath Technologies Inc. | Method of using cryotreatment to treat brain tissue |
| US7422586B2 (en) * | 2001-02-28 | 2008-09-09 | Angiodynamics, Inc. | Tissue surface treatment apparatus and method |
| BRPI0116974B8 (pt) | 2001-04-13 | 2021-06-22 | Becton Dickinson Co | dispositivo de injeção intradérmica com enchimento prévio. |
| US6761715B2 (en) | 2001-04-26 | 2004-07-13 | Ronald J. Carroll | Method and device for neurocryo analgesia and anesthesia |
| GB0111986D0 (en) | 2001-05-16 | 2001-07-04 | Optomed As | Cryosurgical apparatus and methods |
| ES2400055T3 (es) | 2001-05-16 | 2013-04-05 | Eli Lilly And Company | Aparato inyector de medicamentos |
| US20080051776A1 (en) | 2001-05-21 | 2008-02-28 | Galil Medical Ltd. | Thin uninsulated cryoprobe and insulating probe introducer |
| US6786900B2 (en) | 2001-08-13 | 2004-09-07 | Cryovascular Systems, Inc. | Cryotherapy methods for treating vessel dissections and side branch occlusion |
| JP2005503227A (ja) | 2001-09-27 | 2005-02-03 | ガリル メディカル リミテッド | 乳房の腫瘍の冷凍外科治療のための装置および方法 |
| KR20030032629A (ko) | 2001-10-19 | 2003-04-26 | 삼성광주전자 주식회사 | 압축기의 고효율 밸브조립체 |
| US7479139B2 (en) * | 2002-01-04 | 2009-01-20 | Galil Medical Ltd. | Apparatus and method for protecting tissues during cryoablation |
| US7250046B1 (en) | 2002-02-27 | 2007-07-31 | Fallat Lawrence M | Treatment of lower extremity pain |
| CA2478887C (en) | 2002-03-15 | 2013-08-13 | The General Hospital Corporation | Methods and devices for selective disruption of fatty tissue by controlled cooling |
| US20030220647A1 (en) | 2002-05-21 | 2003-11-27 | Mccallum Kevin | Low profile acetabular reamer |
| CN1329008C (zh) * | 2002-06-19 | 2007-08-01 | 帕洛玛医疗技术公司 | 用于处理皮肤和皮下情况的设备 |
| TW557219B (en) | 2002-06-28 | 2003-10-11 | Jiun-Guang Luo | Quick-freezing medical device |
| SE523503C2 (sv) | 2002-07-23 | 2004-04-27 | Jettec Ab | Kapillärrör |
| US6858025B2 (en) | 2002-08-06 | 2005-02-22 | Medically Advanced Designs, Llc | Cryo-surgical apparatus and method of use |
| US7338504B2 (en) | 2002-10-03 | 2008-03-04 | Gibbens Group, L.L.C. | Cycling suturing and knot-tying device |
| US6789545B2 (en) | 2002-10-04 | 2004-09-14 | Sanarus Medical, Inc. | Method and system for cryoablating fibroadenomas |
| DK1549353T3 (da) | 2002-10-09 | 2010-07-12 | Central Iowa Health System | Anvendelse af alfa(1,3)galactosyltransferaseudtrykkende allogene tumorceller til vaccination mod tumorer |
| DE10250629A1 (de) | 2002-10-30 | 2004-05-19 | Tecpharma Licensing Ag | Verfahren und Vorrichtung zur Anzeige und Dosierung bei der Verabreichung eines Produkts |
| US6896666B2 (en) * | 2002-11-08 | 2005-05-24 | Kochamba Family Trust | Cutaneous injection delivery under suction |
| WO2004045434A2 (fr) | 2002-11-18 | 2004-06-03 | N.V. H & O Equipments | Instrument destine aux traitements cryogeniques dans le secteur medical, paramedical et cosmetique |
| US20040122482A1 (en) | 2002-12-20 | 2004-06-24 | James Tung | Nerve proximity method and device |
| US7410484B2 (en) | 2003-01-15 | 2008-08-12 | Cryodynamics, Llc | Cryotherapy probe |
| US7273479B2 (en) | 2003-01-15 | 2007-09-25 | Cryodynamics, Llc | Methods and systems for cryogenic cooling |
| US7083612B2 (en) | 2003-01-15 | 2006-08-01 | Cryodynamics, Llc | Cryotherapy system |
| US6936048B2 (en) | 2003-01-16 | 2005-08-30 | Charlotte-Mecklenburg Hospital Authority | Echogenic needle for transvaginal ultrasound directed reduction of uterine fibroids and an associated method |
| MXPA05009803A (es) | 2003-03-13 | 2006-04-18 | Cheryl M Burgess | Metodos para administrar un material en un paciente para realce dermico. |
| US20040204705A1 (en) | 2003-04-10 | 2004-10-14 | Scimed Life Systems, Inc. | Cryotreatment devices and methods of forming conduction blocks |
| CA2522939A1 (en) | 2003-04-21 | 2004-11-04 | Galil Medical Ltd. | Apparatus and method positioning a therapeutic probe with respect to a therapeutic target |
| US7207985B2 (en) * | 2003-06-25 | 2007-04-24 | Endocare, Inc. | Detachable cryosurgical probe |
| US7160291B2 (en) * | 2003-06-25 | 2007-01-09 | Endocare, Inc. | Detachable cryosurgical probe |
| US6960208B2 (en) | 2003-06-30 | 2005-11-01 | Boston Scientific Scimed, Inc. | Apparatus and methods for delivering energy to a target site within bone |
| US20050004563A1 (en) | 2003-07-01 | 2005-01-06 | Racz N. Sandor | Apparatus and methods for sensing and cooling during application of thermal energy for treating degenerative spinal discs |
| US20050043723A1 (en) | 2003-08-19 | 2005-02-24 | Schering-Plough Healthcare Products, Inc. | Cryosurgery device |
| JP2005080988A (ja) | 2003-09-10 | 2005-03-31 | Ruo Mei Ryan | 冷凍治療装置及び熱伝導針手段 |
| US20050203593A1 (en) | 2003-10-24 | 2005-09-15 | Shanks Steven C. | Method for dermatology therapies in combination with low level laser treatments |
| NZ548680A (en) | 2003-12-22 | 2009-09-25 | Ams Res Corp | Cryosurgical devices for endometrial ablation |
| US7402140B2 (en) | 2004-02-12 | 2008-07-22 | Sanarus Medical, Inc. | Rotational core biopsy device with liquid cryogen adhesion probe |
| US7238184B2 (en) | 2004-03-15 | 2007-07-03 | Boston Scientific Scimed, Inc. | Ablation probe with peltier effect thermal control |
| US7322973B2 (en) * | 2004-03-31 | 2008-01-29 | Cryocath Technologies Inc. | Method and apparatus for preventing atrial fibrillation |
| CA2579145C (en) | 2004-04-01 | 2023-06-27 | The General Hospital Corporation | Method and apparatus for dermatological treatment and tissue reshaping |
| US8177779B2 (en) | 2004-06-02 | 2012-05-15 | Boston Scientific Scimed, Inc. | Controllable pressure cryogenic balloon treatment system and method |
| US20050283148A1 (en) | 2004-06-17 | 2005-12-22 | Janssen William M | Ablation apparatus and system to limit nerve conduction |
| JP2008505666A (ja) | 2004-06-24 | 2008-02-28 | エル． ギルデンバーグ，フィリップ | 半自動縫合装置 |
| US7637918B2 (en) | 2004-08-16 | 2009-12-29 | Zimmer Spine, Inc. | Helical suturing device |
| US20060069385A1 (en) | 2004-09-28 | 2006-03-30 | Scimed Life Systems, Inc. | Methods and apparatus for tissue cryotherapy |
| US20060190035A1 (en) | 2004-10-08 | 2006-08-24 | Sherwood Services Ag | Latching mechanism for forceps |
| US7918849B2 (en) | 2004-10-15 | 2011-04-05 | Baxano, Inc. | Devices and methods for tissue access |
| US7578819B2 (en) | 2005-05-16 | 2009-08-25 | Baxano, Inc. | Spinal access and neural localization |
| US20060089688A1 (en) * | 2004-10-25 | 2006-04-27 | Dorin Panescu | Method and apparatus to reduce wrinkles through application of radio frequency energy to nerves |
| JP4324673B2 (ja) | 2004-11-05 | 2009-09-02 | 国立大学法人東北大学 | ペルチェモジュールによる凍結治療装置 |
| US7297136B2 (en) | 2004-12-06 | 2007-11-20 | Wyrick Ronald E | Medicine injection devices and methods |
| US7604631B2 (en) | 2004-12-15 | 2009-10-20 | Boston Scientific Scimed, Inc. | Efficient controlled cryogenic fluid delivery into a balloon catheter and other treatment devices |
| US8906039B2 (en) | 2005-03-21 | 2014-12-09 | Design Standards Corporation | Suturing device |
| US20060223052A1 (en) | 2005-03-30 | 2006-10-05 | Kimberly-Clark Worldwide, Inc. | Technique for detecting microorganisms |
| US7713266B2 (en) | 2005-05-20 | 2010-05-11 | Myoscience, Inc. | Subdermal cryogenic remodeling of muscles, nerves, connective tissue, and/or adipose tissue (fat) |
| US7850683B2 (en) | 2005-05-20 | 2010-12-14 | Myoscience, Inc. | Subdermal cryogenic remodeling of muscles, nerves, connective tissue, and/or adipose tissue (fat) |
| ATE451878T1 (de) | 2005-05-27 | 2010-01-15 | Inst Tecnologico De Canarias S | Halter für chirurgische nadel zum nähen |
| US20070055173A1 (en) | 2005-08-23 | 2007-03-08 | Sanarus Medical, Inc. | Rotational core biopsy device with liquid cryogen adhesion probe |
| DE102005040259A1 (de) * | 2005-08-24 | 2007-03-01 | Qiagen Gmbh | Verfahren zur Gewinnung von Nukleinsäuren aus Blut |
| US8758375B2 (en) | 2005-09-28 | 2014-06-24 | Olympus Medical Systems Corp | Method for suturing perforation |
| US7572268B2 (en) | 2005-10-13 | 2009-08-11 | Bacoustics, Llc | Apparatus and methods for the selective removal of tissue using combinations of ultrasonic energy and cryogenic energy |
| US7998173B2 (en) | 2005-11-22 | 2011-08-16 | Richard Perkins | Adjustable spinous process spacer device and method of treating spinal stenosis |
| US20080051775A1 (en) * | 2005-11-23 | 2008-02-28 | Evans David K | Multi-modal analgesia delivery system ("MADS") |
| JP4614451B2 (ja) | 2005-12-26 | 2011-01-19 | 日本シャーウッド株式会社 | 医療用縫合具 |
| US20070156125A1 (en) | 2005-12-30 | 2007-07-05 | Russell Delonzor | Encodable cryogenic device |
| US7799018B2 (en) | 2006-01-06 | 2010-09-21 | Olga Goulko | Cryogenic applicator for rejuvenating human skin and related method |
| CA2640148C (en) | 2006-01-27 | 2014-09-09 | Suturtek Incorporated | Apparatus and method for tissue closure |
| US7854754B2 (en) | 2006-02-22 | 2010-12-21 | Zeltiq Aesthetics, Inc. | Cooling device for removing heat from subcutaneous lipid-rich cells |
| US20090299357A1 (en) | 2006-04-24 | 2009-12-03 | Thomas Jefferson University | Cryoneedle and cryotheraphy system |
| US20070255362A1 (en) | 2006-04-28 | 2007-11-01 | Juniper Medical, Inc. | Cryoprotectant for use with a cooling device for improved cooling of subcutaneous lipid-rich cells |
| WO2007129121A1 (en) | 2006-05-08 | 2007-11-15 | Tayside Health Board | Device and method for improved surgical suturing |
| WO2007135629A1 (en) | 2006-05-16 | 2007-11-29 | Orhan Seyfi Aksakal | A needle pusher |
| US20070270925A1 (en) | 2006-05-17 | 2007-11-22 | Juniper Medical, Inc. | Method and apparatus for non-invasively removing heat from subcutaneous lipid-rich cells including a coolant having a phase transition temperature |
| EP1862125B1 (en) | 2006-05-31 | 2011-08-03 | Covidien AG | Medical suturing tool with gripping device |
| CA2659261C (en) | 2006-07-28 | 2017-03-07 | Centre Hospitalier Universitaire De Quebec | Probe, sleeve, system, method and kit for performing percutaneous thermotherapy |
| US9132031B2 (en) | 2006-09-26 | 2015-09-15 | Zeltiq Aesthetics, Inc. | Cooling device having a plurality of controllable cooling elements to provide a predetermined cooling profile |
| US20080077201A1 (en) | 2006-09-26 | 2008-03-27 | Juniper Medical, Inc. | Cooling devices with flexible sensors |
| US8192474B2 (en) | 2006-09-26 | 2012-06-05 | Zeltiq Aesthetics, Inc. | Tissue treatment methods |
| JP2010508130A (ja) | 2006-10-31 | 2010-03-18 | ゼルティック エステティックス インコーポレイテッド | 皮下高脂質細胞または皮下高脂質組織を冷却する方法およびその装置 |
| US9254162B2 (en) | 2006-12-21 | 2016-02-09 | Myoscience, Inc. | Dermal and transdermal cryogenic microprobe systems |
| US8409185B2 (en) | 2007-02-16 | 2013-04-02 | Myoscience, Inc. | Replaceable and/or easily removable needle systems for dermal and transdermal cryogenic remodeling |
| US20080287839A1 (en) | 2007-05-18 | 2008-11-20 | Juniper Medical, Inc. | Method of enhanced removal of heat from subcutaneous lipid-rich cells and treatment apparatus having an actuator |
| US20090018627A1 (en) | 2007-07-13 | 2009-01-15 | Juniper Medical, Inc. | Secure systems for removing heat from lipid-rich regions |
| US20090018626A1 (en) | 2007-07-13 | 2009-01-15 | Juniper Medical, Inc. | User interfaces for a system that removes heat from lipid-rich regions |
| US20090018624A1 (en) | 2007-07-13 | 2009-01-15 | Juniper Medical, Inc. | Limiting use of disposable system patient protection devices |
| US20090018625A1 (en) | 2007-07-13 | 2009-01-15 | Juniper Medical, Inc. | Managing system temperature to remove heat from lipid-rich regions |
| US8523927B2 (en) | 2007-07-13 | 2013-09-03 | Zeltiq Aesthetics, Inc. | System for treating lipid-rich regions |
| EP3488833B1 (en) | 2007-08-21 | 2025-10-22 | Zeltiq Aesthetics, Inc. | Monitoring the cooling of subcutaneous lipid-rich cells, such as the cooling of adipose tissue |
| WO2009065061A1 (en) | 2007-11-14 | 2009-05-22 | Myoscience, Inc. | Pain management using cryogenic remodeling |
| JP2010014656A (ja) | 2008-07-07 | 2010-01-21 | Mitaka Koki Co Ltd | 非接触側面形状測定装置 |
| US20120089211A1 (en) | 2010-04-08 | 2012-04-12 | Myoscience, Inc. | Methods and apparatus for cryogenically treating multiple tissue sites with a single puncture |
| US9295512B2 (en) | 2013-03-15 | 2016-03-29 | Myoscience, Inc. | Methods and devices for pain management |
| US9668800B2 (en) | 2013-03-15 | 2017-06-06 | Myoscience, Inc. | Methods and systems for treatment of spasticity |
| US9610112B2 (en) | 2013-03-15 | 2017-04-04 | Myoscience, Inc. | Cryogenic enhancement of joint function, alleviation of joint stiffness and/or alleviation of pain associated with osteoarthritis |
-
2005
- 2005-12-05 US US11/295,204 patent/US7713266B2/en active Active
-
2006
- 2006-05-18 WO PCT/US2006/019471 patent/WO2006127467A2/en not_active Ceased
- 2006-05-18 EP EP12160639.6A patent/EP2499984B1/en active Active
- 2006-05-18 ES ES06770671T patent/ES2389945T3/es active Active
- 2006-05-18 EP EP06770671A patent/EP1890627B1/en active Active
- 2006-05-18 CA CA002608783A patent/CA2608783A1/en not_active Abandoned
- 2006-05-18 JP JP2008512546A patent/JP5044546B2/ja active Active
-
2010
- 2010-04-12 US US12/758,686 patent/US7998137B2/en not_active Expired - Lifetime
-
2011
- 2011-07-07 US US13/178,451 patent/US9345526B2/en not_active Expired - Lifetime
-
2016
- 2016-05-06 US US15/148,539 patent/US10363080B2/en active Active
-
2019
- 2019-06-13 US US16/440,798 patent/US11963706B2/en active Active
-
2020
- 2020-02-20 US US16/795,951 patent/US11350979B2/en not_active Expired - Lifetime
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10610280B1 (en) | 2019-02-02 | 2020-04-07 | Ayad K. M. Agha | Surgical method and apparatus for destruction and removal of intraperitoneal, visceral, and subcutaneous fat |
Also Published As
| Publication number | Publication date |
|---|---|
| CA2608783A1 (en) | 2006-11-30 |
| EP1890627B1 (en) | 2012-06-20 |
| EP1890627A2 (en) | 2008-02-27 |
| US20120065629A1 (en) | 2012-03-15 |
| EP2499984A1 (en) | 2012-09-19 |
| US7713266B2 (en) | 2010-05-11 |
| US11350979B2 (en) | 2022-06-07 |
| US20070129714A1 (en) | 2007-06-07 |
| WO2006127467A2 (en) | 2006-11-30 |
| JP5044546B2 (ja) | 2012-10-10 |
| US9345526B2 (en) | 2016-05-24 |
| EP2499984B1 (en) | 2016-01-06 |
| US20200188005A1 (en) | 2020-06-18 |
| US10363080B2 (en) | 2019-07-30 |
| WO2006127467A3 (en) | 2007-04-12 |
| US20100198207A1 (en) | 2010-08-05 |
| EP1890627A4 (en) | 2009-10-21 |
| JP2008545462A (ja) | 2008-12-18 |
| US11963706B2 (en) | 2024-04-23 |
| US20160354133A1 (en) | 2016-12-08 |
| US7998137B2 (en) | 2011-08-16 |
| US20190290347A1 (en) | 2019-09-26 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ES2389945T3 (es) | Remodelación criogénica subdérmica de músculos, nervios, tejido conectivo, y/o tejido adiposo (grasa) | |
| US7850683B2 (en) | Subdermal cryogenic remodeling of muscles, nerves, connective tissue, and/or adipose tissue (fat) | |
| US20120089211A1 (en) | Methods and apparatus for cryogenically treating multiple tissue sites with a single puncture | |
| US9039688B2 (en) | Method for reducing hyperdynamic facial wrinkles | |
| US8409185B2 (en) | Replaceable and/or easily removable needle systems for dermal and transdermal cryogenic remodeling | |
| US10939947B2 (en) | Dermal and transdermal cryogenic microprobe systems | |
| US20100036295A1 (en) | Method and apparatus for fractional deformation and treatment of cutaneous and subcutaneous tissue | |
| Har-Shai et al. | Minimally Invasive Technologies for the Treatment | |
| Bogle et al. | Nonsurgical skin tightening | |
| Soin et al. | Nonsurgical Tightening | |
| Khan et al. | Novel Minimally Invasive Fractional/Microneedle Radiofrequency Device and Applications in Cosmetic Dermatology | |
| Koch | Nonablative Facial Skin Rejuvenation |