ES2375624T3 - Microgranulados de liberación controlada y procedimiento para su producción. - Google Patents

Microgranulados de liberación controlada y procedimiento para su producción. Download PDF

Info

Publication number
ES2375624T3
ES2375624T3 ES02760617T ES02760617T ES2375624T3 ES 2375624 T3 ES2375624 T3 ES 2375624T3 ES 02760617 T ES02760617 T ES 02760617T ES 02760617 T ES02760617 T ES 02760617T ES 2375624 T3 ES2375624 T3 ES 2375624T3
Authority
ES
Spain
Prior art keywords
water
layer
release
film layer
soluble
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES02760617T
Other languages
English (en)
Spanish (es)
Inventor
Fumio Yoneda
Fumiya Hamano
Eisaku Kitano
Tetsuya Hosono
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fujimoto Brothers Co Ltd
Original Assignee
Fujimoto Brothers Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fujimoto Brothers Co Ltd filed Critical Fujimoto Brothers Co Ltd
Application granted granted Critical
Publication of ES2375624T3 publication Critical patent/ES2375624T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/485—Morphinan derivatives, e.g. morphine, codeine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5084—Mixtures of one or more drugs in different galenical forms, at least one of which being granules, microcapsules or (coated) microparticles according to A61K9/16 or A61K9/50, e.g. for obtaining a specific release pattern or for combining different drugs

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Emergency Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
ES02760617T 2001-08-17 2002-08-12 Microgranulados de liberación controlada y procedimiento para su producción. Expired - Lifetime ES2375624T3 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2001248426A JP4848101B2 (ja) 2001-08-17 2001-08-17 徐放性マイクロペレット
JP2001248426 2001-08-17
PCT/JP2002/008245 WO2003015758A1 (en) 2001-08-17 2002-08-12 Sustained release micropellets and process for producing the same

Publications (1)

Publication Number Publication Date
ES2375624T3 true ES2375624T3 (es) 2012-03-02

Family

ID=19077585

Family Applications (1)

Application Number Title Priority Date Filing Date
ES02760617T Expired - Lifetime ES2375624T3 (es) 2001-08-17 2002-08-12 Microgranulados de liberación controlada y procedimiento para su producción.

Country Status (9)

Country Link
US (2) US20040208930A1 (https=)
EP (1) EP1417960B1 (https=)
JP (1) JP4848101B2 (https=)
AT (1) ATE531360T1 (https=)
AU (1) AU2002327085B9 (https=)
CA (1) CA2459472C (https=)
DK (1) DK1417960T3 (https=)
ES (1) ES2375624T3 (https=)
WO (1) WO2003015758A1 (https=)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU764453B2 (en) 1999-10-29 2003-08-21 Euro-Celtique S.A. Controlled release hydrocodone formulations
US10179130B2 (en) 1999-10-29 2019-01-15 Purdue Pharma L.P. Controlled release hydrocodone formulations
MXPA03003895A (es) 2000-10-30 2003-07-28 Euro Celtique Sa Formulaciones de hidrocodona de liberacion controlada.
EP1663469A4 (en) * 2003-09-05 2009-01-07 Univ Massachusetts AMPHIPHILIC POLYMER CAPSULES AND ASSOCIATED METHODS OF INTERFACIAL ASSEMBLY
AU2004312059A1 (en) * 2003-12-31 2005-07-21 Actavis Group Hf Atomoxetine formulations
MX2007003813A (es) * 2004-10-01 2007-04-24 Firmenich & Cie Microcapsulas perfumantes o saborizantes que comprenden un supesor de explosion.
JP2008525313A (ja) 2004-12-27 2008-07-17 エーザイ・アール・アンド・ディー・マネジメント株式会社 抗痴呆薬の安定化方法
US20070129402A1 (en) * 2004-12-27 2007-06-07 Eisai Research Institute Sustained release formulations
KR101213345B1 (ko) * 2005-04-28 2012-12-17 에자이 알앤드디 매니지먼트 가부시키가이샤 항치매약을 함유하는 조성물
US20080069891A1 (en) 2006-09-15 2008-03-20 Cima Labs, Inc. Abuse resistant drug formulation
US8445018B2 (en) 2006-09-15 2013-05-21 Cima Labs Inc. Abuse resistant drug formulation
CA2798702A1 (en) 2010-05-11 2011-11-17 Cima Labs Inc. Alcoholresistant metoprolol-containing extended-release oral dosage forms
WO2023187225A1 (en) * 2022-04-01 2023-10-05 Amplicon Ab Alkaline intraoral products

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6058890B2 (ja) * 1978-10-20 1985-12-23 東洋醸造株式会社 抗生物質細粒剤の製造法およびそれを用いる複粒剤
JPS583510A (ja) * 1981-06-29 1983-01-10 住友電気工業株式会社 海底ケ−ブル等の埋設機の積卸方法
JPS5835110A (ja) * 1981-08-28 1983-03-01 Tetsuo Kato 徐放性マイクロカプセル
JPS5944311A (ja) * 1982-09-07 1984-03-12 Santen Pharmaceut Co Ltd 徐放性顆粒およびその製造法
US4777049A (en) * 1983-12-01 1988-10-11 Alza Corporation Constant release system with pulsed release
GB2150434B (en) * 1983-12-01 1987-11-04 Alza Corp Constant rate release systems
DK62184D0 (da) * 1984-02-10 1984-02-10 Benzon As Alfred Diffusionsovertrukket polydepotpraeparat
US4753802A (en) * 1986-03-19 1988-06-28 Alza Corporation Verapamil dosage form
US5026560A (en) * 1987-01-29 1991-06-25 Takeda Chemical Industries, Ltd. Spherical granules having core and their production
JPH0832625B2 (ja) * 1987-01-29 1996-03-29 武田薬品工業株式会社 有核顆粒およびその製造法
US4931285A (en) * 1988-04-28 1990-06-05 Alza Corporation Aqueous based pharmaceutical coating composition for dosage forms
US5202128A (en) * 1989-01-06 1993-04-13 F. H. Faulding & Co. Limited Sustained release pharmaceutical composition
HU205851B (en) * 1989-01-31 1992-07-28 Int Pharma Agentur Systhem of regulated release of the active components and process for producing it
JP2820829B2 (ja) * 1991-03-07 1998-11-05 武田薬品工業株式会社 有核散剤およびその製造方法
US5229135A (en) * 1991-11-22 1993-07-20 Prographarm Laboratories Sustained release diltiazem formulation
IT1264020B (it) * 1993-01-28 1996-09-09 Recordati Chem Pharm Procedimento per la preparazione di microgranuli idonei alla sospensione in liquidi
EP0711166A1 (en) * 1993-07-22 1996-05-15 Warner-Lambert Company Controlled release tacrine drug delivery systems and methods for preparing same
JPH0789849A (ja) * 1993-09-20 1995-04-04 Fujisawa Pharmaceut Co Ltd 徐放性製剤
US6077533A (en) * 1994-05-25 2000-06-20 Purdue Pharma L.P. Powder-layered oral dosage forms
US5411745A (en) * 1994-05-25 1995-05-02 Euro-Celtique, S.A. Powder-layered morphine sulfate formulations
JPH10139659A (ja) * 1996-09-10 1998-05-26 Freunt Ind Co Ltd 球形粒子群、その製造方法及びそれを用いた球形粒子製剤
TW477702B (en) * 1997-10-23 2002-03-01 Dev Center Biotechnology Controlled release tacrine dosage form
SE9704869D0 (sv) * 1997-12-22 1997-12-22 Astra Ab New pharmaceutical formulaton II
FR2794646B1 (fr) * 1999-06-09 2001-09-21 Ethypharm Lab Prod Ethiques Microgranules de sulfate de morphine, procede de preparation et composition les contenant

Also Published As

Publication number Publication date
JP4848101B2 (ja) 2011-12-28
CA2459472A1 (en) 2003-02-27
AU2002327085B9 (en) 2008-08-14
WO2003015758A1 (en) 2003-02-27
US20090011034A1 (en) 2009-01-08
JP2003055199A (ja) 2003-02-26
EP1417960A4 (en) 2008-08-13
CA2459472C (en) 2010-12-14
US20040208930A1 (en) 2004-10-21
DK1417960T3 (da) 2012-02-20
EP1417960B1 (en) 2011-11-02
AU2002327085B2 (en) 2008-02-14
AU2002327085B8 (en) 2008-02-28
US8512744B2 (en) 2013-08-20
EP1417960A1 (en) 2004-05-12
ATE531360T1 (de) 2011-11-15

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