ES2371364T3 - Agentes para el tratamiento de la retinopatía glaucomatosa y de la neuropatía óptica. - Google Patents

Agentes para el tratamiento de la retinopatía glaucomatosa y de la neuropatía óptica. Download PDF

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Publication number
ES2371364T3
ES2371364T3 ES07105047T ES07105047T ES2371364T3 ES 2371364 T3 ES2371364 T3 ES 2371364T3 ES 07105047 T ES07105047 T ES 07105047T ES 07105047 T ES07105047 T ES 07105047T ES 2371364 T3 ES2371364 T3 ES 2371364T3
Authority
ES
Spain
Prior art keywords
composition according
agent
composition
pharmacologically active
cells
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES07105047T
Other languages
English (en)
Spanish (es)
Inventor
Robert Landers
Iok-Hou Pang
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Alcon Inc
Original Assignee
Novartis AG
Alcon Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis AG, Alcon Inc filed Critical Novartis AG
Application granted granted Critical
Publication of ES2371364T3 publication Critical patent/ES2371364T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/325—Carbamic acids; Thiocarbamic acids; Anhydrides or salts thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A61K31/366—Lactones having six-membered rings, e.g. delta-lactones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
    • A61K31/385—Heterocyclic compounds having sulfur as a ring hetero atom having two or more sulfur atoms in the same ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0043—Nose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Ophthalmology & Optometry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Dermatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Otolaryngology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Steroid Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Quinoline Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Saccharide Compounds (AREA)
ES07105047T 2003-12-22 2004-12-17 Agentes para el tratamiento de la retinopatía glaucomatosa y de la neuropatía óptica. Expired - Lifetime ES2371364T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US53177003P 2003-12-22 2003-12-22
US531770 2003-12-22

Publications (1)

Publication Number Publication Date
ES2371364T3 true ES2371364T3 (es) 2011-12-30

Family

ID=34738696

Family Applications (2)

Application Number Title Priority Date Filing Date
ES04814825T Expired - Lifetime ES2282926T3 (es) 2003-12-22 2004-12-17 Agentes para el tratamiento de la retinopatia glaucomatosa y de la neuropatia optica.
ES07105047T Expired - Lifetime ES2371364T3 (es) 2003-12-22 2004-12-17 Agentes para el tratamiento de la retinopatía glaucomatosa y de la neuropatía óptica.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES04814825T Expired - Lifetime ES2282926T3 (es) 2003-12-22 2004-12-17 Agentes para el tratamiento de la retinopatia glaucomatosa y de la neuropatia optica.

Country Status (19)

Country Link
US (2) US20050137146A1 (enExample)
EP (2) EP1803468B1 (enExample)
JP (2) JP4755599B2 (enExample)
KR (1) KR20060127043A (enExample)
CN (1) CN1897972A (enExample)
AT (2) ATE357932T1 (enExample)
AU (1) AU2004308919B2 (enExample)
BR (1) BRPI0417987A (enExample)
CA (1) CA2547852A1 (enExample)
CY (2) CY1106623T1 (enExample)
DE (1) DE602004005617T2 (enExample)
DK (2) DK1696958T3 (enExample)
ES (2) ES2282926T3 (enExample)
MX (1) MXPA06006980A (enExample)
PL (2) PL1803468T3 (enExample)
PT (2) PT1696958E (enExample)
SI (2) SI1696958T1 (enExample)
WO (1) WO2005063295A1 (enExample)
ZA (1) ZA200604862B (enExample)

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WO2005102345A1 (en) * 2004-03-30 2005-11-03 Alcon, Inc. Use of rho kinase inhibitors in the treatment of hearing loss, tinnitus and improving body balance
WO2006030907A1 (ja) * 2004-09-16 2006-03-23 Redox Bioscience Inc. 網膜保護剤
WO2007035356A2 (en) * 2005-09-16 2007-03-29 Bg Implant, Inc. Glaucoma treatment devices and methods
WO2008016095A1 (en) * 2006-08-02 2008-02-07 Santen Pharmaceutical Co., Ltd. PREVENTIVE OR REMEDY FOR KERATOCONJUNCTIVAL DISORDERS CONTAINING Nrf2 ACTIVATOR AS THE ACTIVE INGREDIENT
WO2008108825A2 (en) * 2006-10-10 2008-09-12 Burnham Institute For Medical Research Neuroprotective compositions and methods
WO2008111497A1 (ja) * 2007-03-08 2008-09-18 Santen Pharmaceutical Co., Ltd. トリテルペノイドを有効成分として含有する酸化ストレスが関連する眼疾患の予防又は治療剤
NZ588711A (en) 2008-04-18 2012-10-26 Reata Pharmaceuticals Inc C-17 homologated oleanolic acid derivatives for treating cancer
LT2276493T (lt) 2008-04-18 2019-01-10 Reata Pharmaceuticals, Inc. Antioksidaciniai uždegimo moduliatoriai: oleanolio rūgšties dariniai su amino ir kitomis modifikacijomis c-17
TW201006474A (en) 2008-04-18 2010-02-16 Reata Pharmaceuticals Inc Natural products including an anti-flammatory pharmacore and methods of use
LT2558105T (lt) 2010-04-12 2020-02-10 Reata Pharmaceuticals, Inc. Bardoksolono metilas, skirtas nutukimo gydymui
RU2472475C2 (ru) * 2010-04-20 2013-01-20 Учреждение образования "Белорусский государственный медицинский университет" (УО БГМУ) Способ комбинированного лечения глаукомной оптической нейропатии
WO2012009171A2 (en) * 2010-07-15 2012-01-19 The Schepens Eye Research Institute, Inc. Compositions and methods of treatment of corneal endothelium disorders
RU2447864C1 (ru) * 2010-09-15 2012-04-20 Инна Витальевна Щербинина Способ лечения заболеваний зрительного нерва и сетчатки
CN103702669A (zh) * 2011-06-21 2014-04-02 约翰霍普金斯大学 用于治疗周围神经病变和其他神经退行性疾患的化合物
RU2546019C2 (ru) * 2013-03-02 2015-04-10 Государственное бюджетное образовательное учреждение высшего профессионального образования "Воронежская государственная медицинская академия им. Н.Н. Бурденко" Министерства здравоохранения Российской Федерации Способ лечения глаукомной оптической нейропатии
JP6340673B2 (ja) 2013-05-02 2018-06-13 レティナ ファウンデーション オブ ザ サウスウエストＲｅｔｉｎａ Ｆｏｕｎｄａｔｉｏｎ Ｏｆ Ｔｈｅ Ｓｏｕｔｈｗｅｓｔ 二層型眼用インプラント
AU2015374033B2 (en) 2014-12-31 2020-07-02 Microoptx Inc. Glaucoma treatment devices and methods
US10980667B2 (en) 2015-09-30 2021-04-20 Microoptx Inc. Eye treatment devices and methods
CA3036630A1 (en) 2016-09-12 2018-03-15 St Ip Holding Ag Formulations of 4-methyl-5-(pyrazin-2-yl)-3h-1,2-dithiole-3-thione, taste-modified formulations, and methods of making and using same
EP3509642A1 (en) 2016-09-12 2019-07-17 ST IP Holding AG Formulations of 4-methyl-5-(pyrazin-2-yl)-3h-1, 2-dithiole-3-thione, and methods of making and using same
US10953020B2 (en) 2016-11-08 2021-03-23 Reata Pharmaceuticals, Inc. Methods of treating Alport syndrome using bardoxolone methyl or analogs thereof
RU2647324C1 (ru) * 2017-04-24 2018-03-15 Игорь Евгеньевич Хаценко Способ определения показаний для лечения амблиопии с помощью нейропептидного препарата
KR20230015891A (ko) * 2020-03-30 2023-01-31 우한 뉴로프스 바이오테크놀로지 리미티드 컴퍼니 인간 핵 인자 e2-관련 인자 2의 발현 벡터 및 발현 벡터의 적용
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Also Published As

Publication number Publication date
EP1803468B1 (en) 2011-09-07
JP2011046736A (ja) 2011-03-10
PL1696958T3 (pl) 2007-08-31
ATE523208T1 (de) 2011-09-15
CN1897972A (zh) 2007-01-17
SI1803468T1 (sl) 2011-12-30
EP1696958B1 (en) 2007-03-28
PL1803468T3 (pl) 2012-05-31
DE602004005617T2 (de) 2007-12-13
EP1696958A1 (en) 2006-09-06
DE602004005617D1 (de) 2007-05-10
CY1106623T1 (el) 2012-01-25
WO2005063295A1 (en) 2005-07-14
CY1112393T1 (el) 2015-12-09
AU2004308919A1 (en) 2005-07-14
DK1803468T3 (da) 2011-12-05
HK1097179A1 (en) 2007-06-22
KR20060127043A (ko) 2006-12-11
SI1696958T1 (sl) 2007-08-31
ES2282926T3 (es) 2007-10-16
BRPI0417987A (pt) 2007-04-27
US20050137146A1 (en) 2005-06-23
JP4755599B2 (ja) 2011-08-24
EP1803468A1 (en) 2007-07-04
AU2004308919B2 (en) 2009-11-12
ATE357932T1 (de) 2007-04-15
ZA200604862B (en) 2007-10-31
DK1696958T3 (da) 2007-07-09
US20110144127A1 (en) 2011-06-16
MXPA06006980A (es) 2006-12-14
PT1803468E (pt) 2011-11-23
CA2547852A1 (en) 2005-07-14
JP2007515423A (ja) 2007-06-14
HK1110772A1 (en) 2008-07-25
PT1696958E (pt) 2007-06-04

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