CN1897972A - 用于治疗青光眼性视网膜病和视神经病的活性剂 - Google Patents

用于治疗青光眼性视网膜病和视神经病的活性剂 Download PDF

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Publication number
CN1897972A
CN1897972A CNA2004800384580A CN200480038458A CN1897972A CN 1897972 A CN1897972 A CN 1897972A CN A2004800384580 A CNA2004800384580 A CN A2004800384580A CN 200480038458 A CN200480038458 A CN 200480038458A CN 1897972 A CN1897972 A CN 1897972A
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CN
China
Prior art keywords
pharmacologically active
active agent
optic neuropathy
active derivative
composition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CNA2004800384580A
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English (en)
Chinese (zh)
Inventor
R·A·兰德斯
彭玉豪
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Alcon Universal Ltd
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Filing date
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Application filed by Alcon Universal Ltd filed Critical Alcon Universal Ltd
Publication of CN1897972A publication Critical patent/CN1897972A/zh
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/325—Carbamic acids; Thiocarbamic acids; Anhydrides or salts thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A61K31/366—Lactones having six-membered rings, e.g. delta-lactones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
    • A61K31/385—Heterocyclic compounds having sulfur as a ring hetero atom having two or more sulfur atoms in the same ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0043—Nose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Ophthalmology & Optometry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Molecular Biology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Otolaryngology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Steroid Compounds (AREA)
  • Quinoline Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Saccharide Compounds (AREA)
CNA2004800384580A 2003-12-22 2004-12-17 用于治疗青光眼性视网膜病和视神经病的活性剂 Pending CN1897972A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US53177003P 2003-12-22 2003-12-22
US60/531,770 2003-12-22

Publications (1)

Publication Number Publication Date
CN1897972A true CN1897972A (zh) 2007-01-17

Family

ID=34738696

Family Applications (1)

Application Number Title Priority Date Filing Date
CNA2004800384580A Pending CN1897972A (zh) 2003-12-22 2004-12-17 用于治疗青光眼性视网膜病和视神经病的活性剂

Country Status (19)

Country Link
US (2) US20050137146A1 (enExample)
EP (2) EP1803468B1 (enExample)
JP (2) JP4755599B2 (enExample)
KR (1) KR20060127043A (enExample)
CN (1) CN1897972A (enExample)
AT (2) ATE357932T1 (enExample)
AU (1) AU2004308919B2 (enExample)
BR (1) BRPI0417987A (enExample)
CA (1) CA2547852A1 (enExample)
CY (2) CY1106623T1 (enExample)
DE (1) DE602004005617T2 (enExample)
DK (2) DK1803468T3 (enExample)
ES (2) ES2282926T3 (enExample)
MX (1) MXPA06006980A (enExample)
PL (2) PL1803468T3 (enExample)
PT (2) PT1803468E (enExample)
SI (2) SI1696958T1 (enExample)
WO (1) WO2005063295A1 (enExample)
ZA (1) ZA200604862B (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
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WO2021195876A1 (zh) * 2020-03-30 2021-10-07 武汉纽福斯生物科技有限公司 一种人核因子e2相关因子2的表达载体及其应用

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2021195876A1 (zh) * 2020-03-30 2021-10-07 武汉纽福斯生物科技有限公司 一种人核因子e2相关因子2的表达载体及其应用
CN115279906A (zh) * 2020-03-30 2022-11-01 武汉纽福斯生物科技有限公司 一种人核因子e2相关因子2的表达载体及其应用

Also Published As

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EP1803468A1 (en) 2007-07-04
SI1803468T1 (sl) 2011-12-30
BRPI0417987A (pt) 2007-04-27
JP2011046736A (ja) 2011-03-10
AU2004308919B2 (en) 2009-11-12
MXPA06006980A (es) 2006-12-14
JP4755599B2 (ja) 2011-08-24
JP2007515423A (ja) 2007-06-14
CA2547852A1 (en) 2005-07-14
ES2371364T3 (es) 2011-12-30
ZA200604862B (en) 2007-10-31
PL1803468T3 (pl) 2012-05-31
CY1112393T1 (el) 2015-12-09
DE602004005617T2 (de) 2007-12-13
EP1696958B1 (en) 2007-03-28
PT1803468E (pt) 2011-11-23
US20110144127A1 (en) 2011-06-16
ATE357932T1 (de) 2007-04-15
HK1097179A1 (en) 2007-06-22
SI1696958T1 (sl) 2007-08-31
ES2282926T3 (es) 2007-10-16
EP1803468B1 (en) 2011-09-07
EP1696958A1 (en) 2006-09-06
PT1696958E (pt) 2007-06-04
DK1696958T3 (da) 2007-07-09
WO2005063295A1 (en) 2005-07-14
KR20060127043A (ko) 2006-12-11
HK1110772A1 (en) 2008-07-25
CY1106623T1 (el) 2012-01-25
DK1803468T3 (da) 2011-12-05
DE602004005617D1 (de) 2007-05-10
ATE523208T1 (de) 2011-09-15
AU2004308919A1 (en) 2005-07-14
PL1696958T3 (pl) 2007-08-31
US20050137146A1 (en) 2005-06-23

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