ES2346178T3 - Nuevas composiciones, procedimientos y usos de unión de la albúmina - Google Patents
Nuevas composiciones, procedimientos y usos de unión de la albúmina Download PDFInfo
- Publication number
- ES2346178T3 ES2346178T3 ES08786222.3T ES08786222T ES2346178T3 ES 2346178 T3 ES2346178 T3 ES 2346178T3 ES 08786222 T ES08786222 T ES 08786222T ES 2346178 T3 ES2346178 T3 ES 2346178T3
- Authority
- ES
- Spain
- Prior art keywords
- seq
- albumin binding
- albumin
- polypeptide
- protein
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/315—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/305—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F)
- C07K14/31—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F) from Staphylococcus (G)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/53—Colony-stimulating factor [CSF]
- C07K14/535—Granulocyte CSF; Granulocyte-macrophage CSF
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/605—Glucagons
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/61—Growth hormone [GH], i.e. somatotropin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/745—Blood coagulation or fibrinolysis factors
- C07K14/755—Factors VIII, e.g. factor VIII C (AHF), factor VIII Ag (VWF)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Endocrinology (AREA)
- Immunology (AREA)
- Hematology (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicinal Preparation (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US96261807P | 2007-07-31 | 2007-07-31 | |
| EP07113533 | 2007-07-31 | ||
| US962618P | 2007-07-31 | ||
| EP07113533 | 2007-07-31 | ||
| PCT/EP2008/059389 WO2009016043A2 (en) | 2007-07-31 | 2008-07-17 | New albumin binding compositions, methods and uses |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES2346178T1 ES2346178T1 (es) | 2010-10-13 |
| ES2346178T3 true ES2346178T3 (es) | 2015-11-02 |
Family
ID=40057660
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES08786222.3T Active ES2346178T3 (es) | 2007-07-31 | 2008-07-17 | Nuevas composiciones, procedimientos y usos de unión de la albúmina |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US8937153B2 (cg-RX-API-DMAC7.html) |
| EP (2) | EP2546261A3 (cg-RX-API-DMAC7.html) |
| JP (1) | JP5718638B2 (cg-RX-API-DMAC7.html) |
| CN (2) | CN104710518A (cg-RX-API-DMAC7.html) |
| AU (1) | AU2008281913B2 (cg-RX-API-DMAC7.html) |
| CA (1) | CA2694139C (cg-RX-API-DMAC7.html) |
| DE (1) | DE08786222T1 (cg-RX-API-DMAC7.html) |
| DK (1) | DK2190863T3 (cg-RX-API-DMAC7.html) |
| ES (1) | ES2346178T3 (cg-RX-API-DMAC7.html) |
| HK (1) | HK1211040A1 (cg-RX-API-DMAC7.html) |
| WO (1) | WO2009016043A2 (cg-RX-API-DMAC7.html) |
Families Citing this family (83)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2694139C (en) * | 2007-07-31 | 2018-06-05 | Affibody Ab | Albumin binding polypeptide compositions |
| US20120134984A1 (en) * | 2009-06-01 | 2012-05-31 | Olga Lubman | Molecules with extended half-lives and uses thereof |
| DK2977088T3 (en) * | 2010-03-08 | 2017-10-09 | Ge Healthcare Bioprocess R&D Ab | IMMUNOGLOBULIN G FC REGION BINDING POLYPEPTIDE |
| JP5827218B2 (ja) * | 2010-04-30 | 2015-12-02 | 株式会社三和化学研究所 | 生理活性物質等の生体内安定性向上のためのペプチド及び生体内安定性が向上した生理活性物質 |
| CN110437320B (zh) | 2010-07-09 | 2023-10-20 | 阿菲博迪公司 | 多肽 |
| EP2601216B1 (en) * | 2010-08-02 | 2018-01-03 | MacroGenics, Inc. | Covalent diabodies and uses thereof |
| BR112013007442A2 (pt) | 2010-09-28 | 2019-09-24 | Amylin Pharmaceuticals Llc | polipeptídeos construídos tendo duração de ação realçada |
| BR112013007385B1 (pt) * | 2010-09-28 | 2022-07-26 | Amylin Pharmaceuticals, Llc | Polipeptídeo quimérico, seu uso e composição que o compreende |
| DK2643349T3 (da) | 2010-11-26 | 2019-11-25 | Molecular Partners Ag | Designede repeat-proteiner, der binder til serumalbumin |
| ES2605784T3 (es) * | 2011-05-21 | 2017-03-16 | Macrogenics, Inc. | Dominios de enlazamiento a suero desinmunizados y su uso para extender la vida media en suero |
| WO2013009545A1 (en) * | 2011-07-08 | 2013-01-17 | Amylin Pharmaceuticals, Inc. | Engineered polypeptides having enhanced duration of action with reduced immunogenicity |
| ES2732475T3 (es) | 2011-07-08 | 2019-11-22 | Aegerion Pharmaceuticals Inc | Polipéptidos modificados por ingeniería genética que tienen una duración potenciada de la acción y una inmunogenicidad reducida |
| EP4616914A3 (en) | 2012-02-20 | 2025-11-19 | IPC Research, LLC | Polypeptides binding to human complement c5 |
| EP2844269A4 (en) * | 2012-03-28 | 2016-01-06 | Amylin Pharmaceuticals Llc | TRANSMUCOSAL ADMINISTRATION OF MANIPULATED POLYPEPTIDES |
| JP2020033372A (ja) * | 2012-03-28 | 2020-03-05 | アフィボディ・アーベー | 経口投与 |
| KR20140142298A (ko) * | 2012-03-28 | 2014-12-11 | 애피바디 에이비 | 경구투여 |
| JP2015519345A (ja) | 2012-05-25 | 2015-07-09 | ヤンセン バイオテツク,インコーポレーテツド | 非天然コンセンサスアルブミン結合ドメイン |
| WO2014048977A1 (en) * | 2012-09-25 | 2014-04-03 | Affibody Ab | Albumin binding polzpeptide |
| CN104768976B (zh) | 2012-10-05 | 2020-09-22 | 阿菲博迪公司 | Her3结合多肽 |
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| ES2674983T3 (es) * | 2012-10-25 | 2018-07-05 | Affibody Ab | Método para la separación de proteínas que contienen un dominio que se une a albúmina |
| WO2014076179A1 (en) | 2012-11-14 | 2014-05-22 | Affibody Ab | New polypeptide |
| US9255262B2 (en) * | 2013-03-06 | 2016-02-09 | Vision Global Holdings Ltd. | Albumin-binding arginine deminase and the use thereof |
| USRE48805E1 (en) | 2013-03-06 | 2021-11-02 | Vision Global Holdings Ltd. | Method for cancer targeting treatment and detection of arginine using albumin-binding arginine deiminase fusion protein |
| RU2015142437A (ru) | 2013-03-14 | 2017-04-27 | Дайити Санкио Ко., Лтд | Новые связывающие белки для pcsk9 |
| HK1218534A1 (zh) | 2013-03-14 | 2017-02-24 | 多伦多大学管理委员会 | 支架化肽文库以及其制备和筛选方法 |
| ES2660912T3 (es) | 2013-03-15 | 2018-03-26 | Affibody Ab | Nuevos polipéptidos |
| AU2014254019B2 (en) | 2013-04-18 | 2018-09-27 | Armo Biosciences, Inc. | Methods of using interleukin-10 for treating diseases and disorders |
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| KR20160068744A (ko) | 2013-08-28 | 2016-06-15 | 애피바디 에이비 | 돌연변이된 스캐폴드를 갖는 결합 폴리펩티드 |
| KR102446636B1 (ko) | 2013-08-28 | 2022-09-23 | 스위디쉬 오르펀 바이오비트럼 에이비 (피유비엘) | 인간 보체 c5에 결합하는 안정한 폴리펩티드 |
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| EP3691693A4 (en) | 2017-10-06 | 2021-08-25 | University Of Utah Research Foundation | FUSION PROTEIN FOR TARGETED THERAPY OF AUTOIMMUNE DISEASE |
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| SE509359C2 (sv) | 1989-08-01 | 1999-01-18 | Cemu Bioteknik Ab | Användning av stabiliserade protein- eller peptidkonjugat för framställning av ett läkemedel |
| FR2718452B1 (fr) * | 1994-04-06 | 1996-06-28 | Pf Medicament | Elément d'immunogène, agent immunogène, composition pharmaceutique et procédé de préparation. |
| FR2726471B1 (fr) * | 1994-11-07 | 1997-01-31 | Pf Medicament | Procede pour ameliorer l'immunogenicite d'un compose immunogene ou d'un haptene et application a la preparation de vaccins |
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-
2008
- 2008-07-17 CA CA2694139A patent/CA2694139C/en active Active
- 2008-07-17 CN CN201510071238.8A patent/CN104710518A/zh active Pending
- 2008-07-17 DE DE08786222T patent/DE08786222T1/de active Pending
- 2008-07-17 EP EP12176805.5A patent/EP2546261A3/en not_active Withdrawn
- 2008-07-17 WO PCT/EP2008/059389 patent/WO2009016043A2/en not_active Ceased
- 2008-07-17 AU AU2008281913A patent/AU2008281913B2/en active Active
- 2008-07-17 ES ES08786222.3T patent/ES2346178T3/es active Active
- 2008-07-17 DK DK08786222.3T patent/DK2190863T3/da active
- 2008-07-17 CN CN200880101168.4A patent/CN101765608B/zh active Active
- 2008-07-17 JP JP2010518606A patent/JP5718638B2/ja active Active
- 2008-07-17 US US12/452,731 patent/US8937153B2/en active Active
- 2008-07-17 EP EP08786222.3A patent/EP2190863B1/en active Active
-
2014
- 2014-11-24 US US14/551,931 patent/US10118949B2/en active Active
-
2015
- 2015-12-02 HK HK15111838.6A patent/HK1211040A1/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DK2190863T3 (en) | 2015-11-30 |
| EP2190863B1 (en) | 2015-09-02 |
| EP2190863A2 (en) | 2010-06-02 |
| AU2008281913B2 (en) | 2013-11-07 |
| US10118949B2 (en) | 2018-11-06 |
| CN104710518A (zh) | 2015-06-17 |
| US8937153B2 (en) | 2015-01-20 |
| CN101765608B (zh) | 2015-03-11 |
| CA2694139C (en) | 2018-06-05 |
| EP2546261A3 (en) | 2013-08-14 |
| CN101765608A (zh) | 2010-06-30 |
| AU2008281913A1 (en) | 2009-02-05 |
| ES2346178T1 (es) | 2010-10-13 |
| HK1211040A1 (en) | 2016-05-13 |
| EP2546261A2 (en) | 2013-01-16 |
| JP2010534486A (ja) | 2010-11-11 |
| CA2694139A1 (en) | 2009-02-05 |
| US20100273979A1 (en) | 2010-10-28 |
| JP5718638B2 (ja) | 2015-05-13 |
| DE08786222T1 (de) | 2010-11-25 |
| WO2009016043A2 (en) | 2009-02-05 |
| US20150158916A1 (en) | 2015-06-11 |
| WO2009016043A3 (en) | 2009-06-04 |
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