ES2208766T3 - Procedimiento de deteccion de mutaciones ki-ras y equipo para llevarlo a cabo. - Google Patents
Procedimiento de deteccion de mutaciones ki-ras y equipo para llevarlo a cabo.Info
- Publication number
- ES2208766T3 ES2208766T3 ES96939373T ES96939373T ES2208766T3 ES 2208766 T3 ES2208766 T3 ES 2208766T3 ES 96939373 T ES96939373 T ES 96939373T ES 96939373 T ES96939373 T ES 96939373T ES 2208766 T3 ES2208766 T3 ES 2208766T3
- Authority
- ES
- Spain
- Prior art keywords
- mutations
- pcr
- sec
- ras
- dna
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/118—Prognosis of disease development
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/156—Polymorphic or mutational markers
Landscapes
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- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Analytical Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Pathology (AREA)
- Genetics & Genomics (AREA)
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- Zoology (AREA)
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- Bioinformatics & Cheminformatics (AREA)
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- Biochemistry (AREA)
- Oncology (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Analysing Materials By The Use Of Radiation (AREA)
- Diaphragms For Electromechanical Transducers (AREA)
- Holo Graphy (AREA)
- Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Electrophonic Musical Instruments (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Control And Other Processes For Unpacking Of Materials (AREA)
- Electrically Operated Instructional Devices (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
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| NO954667 | 1995-11-17 | ||
| NO954667A NO954667D0 (no) | 1995-11-17 | 1995-11-17 | Fremgangsmåte til deteksjon av Ki-ras mutasjoner |
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| ES2208766T3 true ES2208766T3 (es) | 2004-06-16 |
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| ES03020560T Expired - Lifetime ES2262930T3 (es) | 1995-11-17 | 1996-11-15 | Procedimiento de deteccion de la mutaciones ki-ras. |
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| ES03020560T Expired - Lifetime ES2262930T3 (es) | 1995-11-17 | 1996-11-15 | Procedimiento de deteccion de la mutaciones ki-ras. |
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| PT (2) | PT1394272E (cg-RX-API-DMAC10.html) |
| WO (1) | WO1997019191A1 (cg-RX-API-DMAC10.html) |
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| GB9715034D0 (en) * | 1997-07-18 | 1997-09-24 | Zeneca Ltd | Assay |
| US6964846B1 (en) * | 1999-04-09 | 2005-11-15 | Exact Sciences Corporation | Methods for detecting nucleic acids indicative of cancer |
| US6531302B1 (en) * | 1999-04-12 | 2003-03-11 | Nanogen/Becton Dickinson Partnership | Anchored strand displacement amplification on an electronically addressable microchip |
| US6849403B1 (en) | 1999-09-08 | 2005-02-01 | Exact Sciences Corporation | Apparatus and method for drug screening |
| US6586177B1 (en) | 1999-09-08 | 2003-07-01 | Exact Sciences Corporation | Methods for disease detection |
| DE60043896D1 (de) * | 1999-12-07 | 2010-04-08 | Exact Sciences Corp | Verfahren zum nachweis von lungenneoplasmen in fäkalen proben |
| US6605451B1 (en) * | 2000-06-06 | 2003-08-12 | Xtrana, Inc. | Methods and devices for multiplexing amplification reactions |
| US7087414B2 (en) | 2000-06-06 | 2006-08-08 | Applera Corporation | Methods and devices for multiplexing amplification reactions |
| EP2351853A1 (en) * | 2000-06-06 | 2011-08-03 | Life Technologies Corporation | Method and devices for multiplexing amplification reactions |
| US7482116B2 (en) | 2002-06-07 | 2009-01-27 | Dna Genotek Inc. | Compositions and methods for obtaining nucleic acids from sputum |
| EP3000899A1 (en) | 2002-12-04 | 2016-03-30 | Applied Biosystems, LLC | Multiplex amplification of polynucleotides |
| US20080124714A1 (en) * | 2004-05-14 | 2008-05-29 | Exact Sciences Corporation | Method for Stabilizing Biological Samples for Nucleic Acid Analysis |
| US20070134709A1 (en) * | 2005-12-14 | 2007-06-14 | Xiping Xu | Usages of MTHFR gene polymorphisms in predicting homocysteine level, disease risk, and treatment effects and related methods and kit |
| GB2435512A (en) | 2006-02-23 | 2007-08-29 | Mologic Ltd | A binding assay and assay device |
| US8768629B2 (en) | 2009-02-11 | 2014-07-01 | Caris Mpi, Inc. | Molecular profiling of tumors |
| IL282783B2 (en) | 2006-05-18 | 2023-09-01 | Caris Mpi Inc | A system and method for determining a personalized medical intervention for a disease stage |
| US8583380B2 (en) | 2008-09-05 | 2013-11-12 | Aueon, Inc. | Methods for stratifying and annotating cancer drug treatment options |
| EP2350320A4 (en) | 2008-11-12 | 2012-11-14 | Caris Life Sciences Luxembourg Holdings | METHOD AND SYSTEMS FOR USE OF EXOSOMES FOR THE DETERMINATION OF PHENOTYPES |
| WO2011082321A1 (en) * | 2009-12-31 | 2011-07-07 | Van Andel Research Institute | Methods for diagnosing the malignant potential of pancreatic cystic lesions |
| CN103237901B (zh) | 2010-03-01 | 2016-08-03 | 卡里斯生命科学瑞士控股有限责任公司 | 用于治疗诊断的生物标志物 |
| JP2013526852A (ja) | 2010-04-06 | 2013-06-27 | カリス ライフ サイエンシズ ルクセンブルク ホールディングス | 疾患に対する循環バイオマーカー |
| JP5986572B2 (ja) | 2010-09-24 | 2016-09-06 | ザ ボード オブ トラスティーズ オブ ザ レランド スタンフォード ジュニア ユニバーシティー | 固定化プライマーを使用した標的ｄｎａの直接的な捕捉、増幅、および配列決定 |
| GB201107466D0 (en) | 2011-05-05 | 2011-06-15 | Loktionov Alexandre | Device and method for non-invasive collection of colorectal mucocellular layer and disease detection |
| CN102796811B (zh) * | 2011-05-26 | 2013-12-18 | 上海赛安生物医药科技有限公司 | 检测kras突变的试剂及方法 |
| CN106442039B (zh) | 2011-06-19 | 2020-08-07 | 阿博根公司 | 用于样品采集的装置、溶液和方法 |
| WO2013074438A1 (en) * | 2011-11-17 | 2013-05-23 | The Johns Hopkins University | Differential identification of pancreatic cysts |
| BR112015012616A2 (pt) * | 2012-11-30 | 2017-09-12 | Applied Proteomics Inc | método para avaliação da presença ou risco de tumores de cólon |
| IL247662B2 (en) | 2014-03-07 | 2025-02-01 | Dna Genotek Inc | Composition and method for stabilizing nucleic acids in biological samples |
| JP2018517892A (ja) | 2015-04-10 | 2018-07-05 | アプライド プロテオミクス，インク． | 結腸直腸癌と進行腺腫を検知するためのタンパク質バイオマーカーパネル |
| US10753936B2 (en) | 2016-07-22 | 2020-08-25 | Van Andel Research Institute | Method of detecting the level of a glycan |
| TW202015719A (zh) | 2018-06-19 | 2020-05-01 | 美商尼恩醫療公司 | 新抗原及其用途 |
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| US4871838A (en) * | 1985-07-23 | 1989-10-03 | The Board Of Rijks Universiteit Leiden | Probes and methods for detecting activated ras oncogenes |
| US5137806A (en) * | 1989-12-11 | 1992-08-11 | Board Of Regents, The University Of Texas System | Methods and compositions for the detection of sequences in selected DNA molecules |
| IL97222A (en) * | 1990-02-16 | 1995-08-31 | Orion Yhtymae Oy | Method and reagent for determining specific nucleotide variations |
| DE69333289T2 (de) | 1992-04-01 | 2004-08-26 | The Johns Hopkins University School Of Medicine | Verfahren zur bestimmung von säugetier nukleinsäuren aus stuhlproben und dafür benötigte reagenzien |
| ATE198358T1 (de) * | 1992-04-27 | 2001-01-15 | Dartmouth College | Detektion von gensequenzen in biologischen flüssigkeiten |
| JPH06167492A (ja) * | 1992-11-30 | 1994-06-14 | Otsuka Pharmaceut Co Ltd | 変異癌遺伝子の検出測定方法 |
| DE19512369A1 (de) * | 1995-04-01 | 1996-10-02 | Boehringer Mannheim Gmbh | Vorrichtung zur Isolierung von Nukleinsäuren |
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1995
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1996
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1998
- 1998-05-15 NO NO19982246A patent/NO324963B1/no not_active IP Right Cessation
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| ATE251222T1 (de) | 2003-10-15 |
| DE69635848D1 (de) | 2006-04-27 |
| JP2000500346A (ja) | 2000-01-18 |
| DE69635848T2 (de) | 2006-11-30 |
| EP0868529A1 (en) | 1998-10-07 |
| AU7656996A (en) | 1997-06-11 |
| ATE318934T1 (de) | 2006-03-15 |
| DE69630234T2 (de) | 2004-08-19 |
| NO982246L (no) | 1998-07-07 |
| EP0868529B1 (en) | 2003-10-01 |
| AU723980B2 (en) | 2000-09-07 |
| DK1394272T3 (da) | 2006-07-03 |
| DK0868529T3 (da) | 2004-02-02 |
| NZ322619A (en) | 1999-04-29 |
| PT868529E (pt) | 2004-02-27 |
| US6440661B1 (en) | 2002-08-27 |
| NO954667D0 (no) | 1995-11-17 |
| DE69630234D1 (de) | 2003-11-06 |
| EP1394272B1 (en) | 2006-03-01 |
| WO1997019191A1 (en) | 1997-05-29 |
| AU723980C (en) | 2002-10-24 |
| PT1394272E (pt) | 2006-07-31 |
| ES2262930T3 (es) | 2006-12-01 |
| NO982246D0 (no) | 1998-05-15 |
| NO324963B1 (no) | 2008-01-14 |
| EP1394272A1 (en) | 2004-03-03 |
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