DE69630234D1 - Verfahren zur bestimung von ki-ras mutationen und dieses leistender testsatz - Google Patents

Verfahren zur bestimung von ki-ras mutationen und dieses leistender testsatz

Info

Publication number
DE69630234D1
DE69630234D1 DE69630234T DE69630234T DE69630234D1 DE 69630234 D1 DE69630234 D1 DE 69630234D1 DE 69630234 T DE69630234 T DE 69630234T DE 69630234 T DE69630234 T DE 69630234T DE 69630234 D1 DE69630234 D1 DE 69630234D1
Authority
DE
Germany
Prior art keywords
determining
ras mutations
performance test
test set
pcr
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69630234T
Other languages
English (en)
Other versions
DE69630234T2 (de
Inventor
Dagfinn Ogreid
Arve Ulvik
Jan Jacob Koornstra
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
NORDIAG AS
Original Assignee
NORDIAG AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by NORDIAG AS filed Critical NORDIAG AS
Application granted granted Critical
Publication of DE69630234D1 publication Critical patent/DE69630234D1/de
Publication of DE69630234T2 publication Critical patent/DE69630234T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/118Prognosis of disease development
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/156Polymorphic or mutational markers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pathology (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Hospice & Palliative Care (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Oncology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Analysing Materials By The Use Of Radiation (AREA)
  • Saccharide Compounds (AREA)
  • Holo Graphy (AREA)
  • Electrophonic Musical Instruments (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Control And Other Processes For Unpacking Of Materials (AREA)
  • Diaphragms For Electromechanical Transducers (AREA)
  • Electrically Operated Instructional Devices (AREA)
DE69630234T 1995-11-17 1996-11-15 Verfahren zur bestimung von ki-ras mutationen und dieses leistender testsatz Expired - Fee Related DE69630234T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
NO954667 1995-11-17
NO954667A NO954667D0 (no) 1995-11-17 1995-11-17 Fremgangsmåte til deteksjon av Ki-ras mutasjoner
PCT/NO1996/000271 WO1997019191A1 (en) 1995-11-17 1996-11-15 Method for detection of ki-ras mutations and kit to perform it

Publications (2)

Publication Number Publication Date
DE69630234D1 true DE69630234D1 (de) 2003-11-06
DE69630234T2 DE69630234T2 (de) 2004-08-19

Family

ID=19898772

Family Applications (2)

Application Number Title Priority Date Filing Date
DE69630234T Expired - Fee Related DE69630234T2 (de) 1995-11-17 1996-11-15 Verfahren zur bestimung von ki-ras mutationen und dieses leistender testsatz
DE69635848T Expired - Fee Related DE69635848T2 (de) 1995-11-17 1996-11-15 Verfahren zum Nachweis von Ki-ras Mutationen

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE69635848T Expired - Fee Related DE69635848T2 (de) 1995-11-17 1996-11-15 Verfahren zum Nachweis von Ki-ras Mutationen

Country Status (12)

Country Link
US (1) US6440661B1 (de)
EP (2) EP1394272B1 (de)
JP (1) JP2000500346A (de)
AT (2) ATE318934T1 (de)
AU (1) AU723980C (de)
DE (2) DE69630234T2 (de)
DK (2) DK0868529T3 (de)
ES (2) ES2262930T3 (de)
NO (2) NO954667D0 (de)
NZ (1) NZ322619A (de)
PT (2) PT868529E (de)
WO (1) WO1997019191A1 (de)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9715034D0 (en) * 1997-07-18 1997-09-24 Zeneca Ltd Assay
AU767983B2 (en) * 1999-04-09 2003-11-27 Esoterix Genetic Laboratories, Llc Methods for detecting nucleic acids indicative of cancer
US6531302B1 (en) * 1999-04-12 2003-03-11 Nanogen/Becton Dickinson Partnership Anchored strand displacement amplification on an electronically addressable microchip
US6586177B1 (en) 1999-09-08 2003-07-01 Exact Sciences Corporation Methods for disease detection
CA2394921A1 (en) 1999-12-07 2001-06-14 Anthony P. Shuber Supracolonic aerodigestive neoplasm detection
EP2351853A1 (de) * 2000-06-06 2011-08-03 Life Technologies Corporation Methode und Vorrichtungen für multiplex Amplifizierungsreaktionen
US7087414B2 (en) 2000-06-06 2006-08-08 Applera Corporation Methods and devices for multiplexing amplification reactions
US6605451B1 (en) * 2000-06-06 2003-08-12 Xtrana, Inc. Methods and devices for multiplexing amplification reactions
US7482116B2 (en) 2002-06-07 2009-01-27 Dna Genotek Inc. Compositions and methods for obtaining nucleic acids from sputum
EP3000899A1 (de) 2002-12-04 2016-03-30 Applied Biosystems, LLC Multiplexverstärkung von polynucleotiden
WO2005113769A1 (en) * 2004-05-14 2005-12-01 Exact Sciences Corporation Method for stabilizing biological samples for nucleic acid analysis
US20070134709A1 (en) * 2005-12-14 2007-06-14 Xiping Xu Usages of MTHFR gene polymorphisms in predicting homocysteine level, disease risk, and treatment effects and related methods and kit
GB2435512A (en) 2006-02-23 2007-08-29 Mologic Ltd A binding assay and assay device
IL282783B2 (en) 2006-05-18 2023-09-01 Caris Mpi Inc A system and method for determining a personalized medical intervention for a disease stage
US8768629B2 (en) 2009-02-11 2014-07-01 Caris Mpi, Inc. Molecular profiling of tumors
WO2010028288A2 (en) 2008-09-05 2010-03-11 Aueon, Inc. Methods for stratifying and annotating cancer drug treatment options
CN107254538A (zh) 2008-11-12 2017-10-17 卡里斯生命科学瑞士控股有限责任公司 使用外来体来确定表现型的方法和系统
EP2519644A4 (de) * 2009-12-31 2013-11-06 Van Andel Res Inst Verfahren zur diagnose des malignen potenzials von zystischen pankreasläsionen
JP5808349B2 (ja) 2010-03-01 2015-11-10 カリス ライフ サイエンシズ スウィッツァーランド ホールディングスゲーエムベーハー セラノーシスのためのバイオマーカー
CA2795776A1 (en) 2010-04-06 2011-10-13 Caris Life Sciences Luxembourg Holdings, S.A.R.L. Circulating biomarkers for disease
MX346956B (es) 2010-09-24 2017-04-06 Univ Leland Stanford Junior Captura directa, amplificación y secuenciación de objetivo adn usando cebadores inmovilizados.
GB201107466D0 (en) 2011-05-05 2011-06-15 Loktionov Alexandre Device and method for non-invasive collection of colorectal mucocellular layer and disease detection
CN102796811B (zh) * 2011-05-26 2013-12-18 上海赛安生物医药科技有限公司 检测kras突变的试剂及方法
EP3150702B1 (de) 2011-06-19 2021-05-19 DNA Genotek, Inc. Vorrichtungen, lösungen und verfahren zur probenentnahme
JP5947392B2 (ja) * 2011-11-17 2016-07-06 ザ ジョンズ ホプキンス ユニバーシティー 膵嚢胞の鑑別
US20140234854A1 (en) * 2012-11-30 2014-08-21 Applied Proteomics, Inc. Method for evaluation of presence of or risk of colon tumors
SG10201807736SA (en) 2014-03-07 2018-10-30 Dna Genotek Inc Composition and method for stabilizing nucleic acids in biological samples
GB2545361B (en) 2015-04-10 2018-01-24 Applied Proteomics Inc Methods of assessing colorectal cancer status
US10753936B2 (en) 2016-07-22 2020-08-25 Van Andel Research Institute Method of detecting the level of a glycan

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4871838A (en) * 1985-07-23 1989-10-03 The Board Of Rijks Universiteit Leiden Probes and methods for detecting activated ras oncogenes
US5137806A (en) * 1989-12-11 1992-08-11 Board Of Regents, The University Of Texas System Methods and compositions for the detection of sequences in selected DNA molecules
IL97222A (en) * 1990-02-16 1995-08-31 Orion Yhtymae Oy Method and Responder for Determining Special Changes to Nucleotide
ES2210239T3 (es) 1992-04-01 2004-07-01 The Johns Hopkins University School Of Medicine Metodo para detectar acidos nucleicos de mamiferos aislados en heces y reactivos para el mismo.
ATE198358T1 (de) * 1992-04-27 2001-01-15 Dartmouth College Detektion von gensequenzen in biologischen flüssigkeiten
JPH06167492A (ja) * 1992-11-30 1994-06-14 Otsuka Pharmaceut Co Ltd 変異癌遺伝子の検出測定方法
DE19512369A1 (de) * 1995-04-01 1996-10-02 Boehringer Mannheim Gmbh Vorrichtung zur Isolierung von Nukleinsäuren

Also Published As

Publication number Publication date
NZ322619A (en) 1999-04-29
PT868529E (pt) 2004-02-27
AU723980B2 (en) 2000-09-07
ATE318934T1 (de) 2006-03-15
EP1394272A1 (de) 2004-03-03
DE69635848T2 (de) 2006-11-30
EP0868529A1 (de) 1998-10-07
DE69630234T2 (de) 2004-08-19
US6440661B1 (en) 2002-08-27
ES2208766T3 (es) 2004-06-16
DK1394272T3 (da) 2006-07-03
EP0868529B1 (de) 2003-10-01
NO982246L (no) 1998-07-07
ATE251222T1 (de) 2003-10-15
DK0868529T3 (da) 2004-02-02
DE69635848D1 (de) 2006-04-27
AU723980C (en) 2002-10-24
NO324963B1 (no) 2008-01-14
JP2000500346A (ja) 2000-01-18
PT1394272E (pt) 2006-07-31
NO954667D0 (no) 1995-11-17
ES2262930T3 (es) 2006-12-01
WO1997019191A1 (en) 1997-05-29
AU7656996A (en) 1997-06-11
NO982246D0 (no) 1998-05-15
EP1394272B1 (de) 2006-03-01

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8339 Ceased/non-payment of the annual fee