DE69635848D1 - Verfahren zum Nachweis von Ki-ras Mutationen - Google Patents

Verfahren zum Nachweis von Ki-ras Mutationen

Info

Publication number
DE69635848D1
DE69635848D1 DE69635848T DE69635848T DE69635848D1 DE 69635848 D1 DE69635848 D1 DE 69635848D1 DE 69635848 T DE69635848 T DE 69635848T DE 69635848 T DE69635848 T DE 69635848T DE 69635848 D1 DE69635848 D1 DE 69635848D1
Authority
DE
Germany
Prior art keywords
ras mutations
detection
pcr
tissue
allele specific
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69635848T
Other languages
English (en)
Other versions
DE69635848T2 (de
Inventor
Arve Ulrik
Jan Jacob Koornstra
Dagfinn Ogreid
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
NORDIAG AS
Original Assignee
NORDIAG AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by NORDIAG AS filed Critical NORDIAG AS
Publication of DE69635848D1 publication Critical patent/DE69635848D1/de
Application granted granted Critical
Publication of DE69635848T2 publication Critical patent/DE69635848T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/118—Prognosis of disease development
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pathology (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Hospice & Palliative Care (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Oncology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Analysing Materials By The Use Of Radiation (AREA)
  • Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Electrically Operated Instructional Devices (AREA)
  • Saccharide Compounds (AREA)
  • Electrophonic Musical Instruments (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Holo Graphy (AREA)
  • Diaphragms For Electromechanical Transducers (AREA)
  • Control And Other Processes For Unpacking Of Materials (AREA)
DE69635848T 1995-11-17 1996-11-15 Verfahren zum Nachweis von Ki-ras Mutationen Expired - Fee Related DE69635848T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
NO954667A NO954667D0 (no) 1995-11-17 1995-11-17 Fremgangsmåte til deteksjon av Ki-ras mutasjoner
NO954667 1995-11-17

Publications (2)

Publication Number Publication Date
DE69635848D1 true DE69635848D1 (de) 2006-04-27
DE69635848T2 DE69635848T2 (de) 2006-11-30

Family

ID=19898772

Family Applications (2)

Application Number Title Priority Date Filing Date
DE69630234T Expired - Fee Related DE69630234T2 (de) 1995-11-17 1996-11-15 Verfahren zur bestimung von ki-ras mutationen und dieses leistender testsatz
DE69635848T Expired - Fee Related DE69635848T2 (de) 1995-11-17 1996-11-15 Verfahren zum Nachweis von Ki-ras Mutationen

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DE69630234T Expired - Fee Related DE69630234T2 (de) 1995-11-17 1996-11-15 Verfahren zur bestimung von ki-ras mutationen und dieses leistender testsatz

Country Status (12)

Country Link
US (1) US6440661B1 (de)
EP (2) EP0868529B1 (de)
JP (1) JP2000500346A (de)
AT (2) ATE318934T1 (de)
AU (1) AU723980C (de)
DE (2) DE69630234T2 (de)
DK (2) DK1394272T3 (de)
ES (2) ES2262930T3 (de)
NO (2) NO954667D0 (de)
NZ (1) NZ322619A (de)
PT (2) PT868529E (de)
WO (1) WO1997019191A1 (de)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9715034D0 (en) * 1997-07-18 1997-09-24 Zeneca Ltd Assay
CA2366778C (en) * 1999-04-09 2008-07-22 Exact Sciences Corporation Methods for detecting nucleic acids indicative of cancer
US6531302B1 (en) * 1999-04-12 2003-03-11 Nanogen/Becton Dickinson Partnership Anchored strand displacement amplification on an electronically addressable microchip
US6586177B1 (en) 1999-09-08 2003-07-01 Exact Sciences Corporation Methods for disease detection
WO2001042781A2 (en) 1999-12-07 2001-06-14 Exact Sciences Corporation Supracolonic aerodigestive neoplasm detection
EP2351853A1 (de) * 2000-06-06 2011-08-03 Life Technologies Corporation Methode und Vorrichtungen für multiplex Amplifizierungsreaktionen
US7087414B2 (en) 2000-06-06 2006-08-08 Applera Corporation Methods and devices for multiplexing amplification reactions
US6605451B1 (en) * 2000-06-06 2003-08-12 Xtrana, Inc. Methods and devices for multiplexing amplification reactions
US7482116B2 (en) 2002-06-07 2009-01-27 Dna Genotek Inc. Compositions and methods for obtaining nucleic acids from sputum
US8323897B2 (en) 2002-12-04 2012-12-04 Applied Biosystems, Llc Multiplex amplification of polynucleotides
WO2005113769A1 (en) * 2004-05-14 2005-12-01 Exact Sciences Corporation Method for stabilizing biological samples for nucleic acid analysis
US20070134709A1 (en) * 2005-12-14 2007-06-14 Xiping Xu Usages of MTHFR gene polymorphisms in predicting homocysteine level, disease risk, and treatment effects and related methods and kit
GB2435512A (en) 2006-02-23 2007-08-29 Mologic Ltd A binding assay and assay device
US8768629B2 (en) 2009-02-11 2014-07-01 Caris Mpi, Inc. Molecular profiling of tumors
CN101449162B (zh) 2006-05-18 2013-07-31 分子压型学会股份有限公司 确定针对病状的个性化医疗介入的系统和方法
US8583380B2 (en) 2008-09-05 2013-11-12 Aueon, Inc. Methods for stratifying and annotating cancer drug treatment options
GB2463401B (en) 2008-11-12 2014-01-29 Caris Life Sciences Luxembourg Holdings S A R L Characterizing prostate disorders by analysis of microvesicles
US20130005598A1 (en) * 2009-12-31 2013-01-03 The Regents Of The University Of Michigan Methods for Diagnosing The Malignant Potential of Pancreatic Cystic Lesions
AU2011223789A1 (en) 2010-03-01 2012-09-20 Caris Life Sciences Switzerland Holdings Gmbh Biomarkers for theranostics
CA2795776A1 (en) 2010-04-06 2011-10-13 Caris Life Sciences Luxembourg Holdings, S.A.R.L. Circulating biomarkers for disease
IN2013MN00522A (de) 2010-09-24 2015-05-29 Univ Leland Stanford Junior
GB201107466D0 (en) 2011-05-05 2011-06-15 Loktionov Alexandre Device and method for non-invasive collection of colorectal mucocellular layer and disease detection
CN102796811B (zh) * 2011-05-26 2013-12-18 上海赛安生物医药科技有限公司 检测kras突变的试剂及方法
EP2721140B1 (de) 2011-06-19 2016-11-23 Abogen, Inc. Vorrichtungen, lösungen und verfahren zur probenentnahme
US9637796B2 (en) * 2011-11-17 2017-05-02 The Johns Hopkins University Differential identification of pancreatic cysts
CA2893158A1 (en) * 2012-11-30 2014-06-05 Applied Proteomics, Inc. Method for evaluation of presence of or risk of colon tumors
DK3114225T3 (da) 2014-03-07 2021-07-26 Dna Genotek Inc Sammensætning og fremgangsmåde til stabilisering af nukleinsyrer i biologiske prøver
GB2545361B (en) 2015-04-10 2018-01-24 Applied Proteomics Inc Methods of assessing colorectal cancer status
US10753936B2 (en) 2016-07-22 2020-08-25 Van Andel Research Institute Method of detecting the level of a glycan

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4871838A (en) * 1985-07-23 1989-10-03 The Board Of Rijks Universiteit Leiden Probes and methods for detecting activated ras oncogenes
US5137806A (en) * 1989-12-11 1992-08-11 Board Of Regents, The University Of Texas System Methods and compositions for the detection of sequences in selected DNA molecules
IL97222A (en) * 1990-02-16 1995-08-31 Orion Yhtymae Oy Method and Responder for Determining Special Changes to Nucleotide
EP0672181B1 (de) 1992-04-01 2003-11-05 The Johns Hopkins University School Of Medicine Verfahren zur bestimmung von säugetier nukleinsäuren aus stuhlproben und dafür benötigte reagenzien
ATE198358T1 (de) 1992-04-27 2001-01-15 Dartmouth College Detektion von gensequenzen in biologischen flüssigkeiten
JPH06167492A (ja) * 1992-11-30 1994-06-14 Otsuka Pharmaceut Co Ltd 変異癌遺伝子の検出測定方法
DE19512369A1 (de) * 1995-04-01 1996-10-02 Boehringer Mannheim Gmbh Vorrichtung zur Isolierung von Nukleinsäuren

Also Published As

Publication number Publication date
AU7656996A (en) 1997-06-11
US6440661B1 (en) 2002-08-27
ES2262930T3 (es) 2006-12-01
PT1394272E (pt) 2006-07-31
NO982246L (no) 1998-07-07
ATE251222T1 (de) 2003-10-15
DE69630234T2 (de) 2004-08-19
EP0868529B1 (de) 2003-10-01
DK1394272T3 (da) 2006-07-03
ATE318934T1 (de) 2006-03-15
ES2208766T3 (es) 2004-06-16
EP1394272A1 (de) 2004-03-03
WO1997019191A1 (en) 1997-05-29
NO982246D0 (no) 1998-05-15
NO954667D0 (no) 1995-11-17
NZ322619A (en) 1999-04-29
PT868529E (pt) 2004-02-27
DE69635848T2 (de) 2006-11-30
DE69630234D1 (de) 2003-11-06
EP1394272B1 (de) 2006-03-01
AU723980B2 (en) 2000-09-07
AU723980C (en) 2002-10-24
DK0868529T3 (da) 2004-02-02
JP2000500346A (ja) 2000-01-18
NO324963B1 (no) 2008-01-14
EP0868529A1 (de) 1998-10-07

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee