ATE318934T1 - Verfahren zum nachweis von ki-ras mutationen - Google Patents

Verfahren zum nachweis von ki-ras mutationen

Info

Publication number
ATE318934T1
ATE318934T1 AT03020560T AT03020560T ATE318934T1 AT E318934 T1 ATE318934 T1 AT E318934T1 AT 03020560 T AT03020560 T AT 03020560T AT 03020560 T AT03020560 T AT 03020560T AT E318934 T1 ATE318934 T1 AT E318934T1
Authority
AT
Austria
Prior art keywords
detecting
ras mutations
pcr
tissue
allele specific
Prior art date
Application number
AT03020560T
Other languages
English (en)
Inventor
Dagfinn Ogreid
Arve Ulvik
Jan Jacob Koornstra
Original Assignee
Nordiag As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nordiag As filed Critical Nordiag As
Application granted granted Critical
Publication of ATE318934T1 publication Critical patent/ATE318934T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/118—Prognosis of disease development
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pathology (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Hospice & Palliative Care (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Oncology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Analysing Materials By The Use Of Radiation (AREA)
  • Control And Other Processes For Unpacking Of Materials (AREA)
  • Holo Graphy (AREA)
  • Diaphragms For Electromechanical Transducers (AREA)
  • Saccharide Compounds (AREA)
  • Electrically Operated Instructional Devices (AREA)
  • Electrophonic Musical Instruments (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
AT03020560T 1995-11-17 1996-11-15 Verfahren zum nachweis von ki-ras mutationen ATE318934T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
NO954667A NO954667D0 (no) 1995-11-17 1995-11-17 Fremgangsmåte til deteksjon av Ki-ras mutasjoner

Publications (1)

Publication Number Publication Date
ATE318934T1 true ATE318934T1 (de) 2006-03-15

Family

ID=19898772

Family Applications (2)

Application Number Title Priority Date Filing Date
AT03020560T ATE318934T1 (de) 1995-11-17 1996-11-15 Verfahren zum nachweis von ki-ras mutationen
AT96939373T ATE251222T1 (de) 1995-11-17 1996-11-15 Verfahren zur bestimung von ki-ras mutationen und dieses leistender testsatz

Family Applications After (1)

Application Number Title Priority Date Filing Date
AT96939373T ATE251222T1 (de) 1995-11-17 1996-11-15 Verfahren zur bestimung von ki-ras mutationen und dieses leistender testsatz

Country Status (12)

Country Link
US (1) US6440661B1 (de)
EP (2) EP0868529B1 (de)
JP (1) JP2000500346A (de)
AT (2) ATE318934T1 (de)
AU (1) AU723980C (de)
DE (2) DE69635848T2 (de)
DK (2) DK0868529T3 (de)
ES (2) ES2262930T3 (de)
NO (2) NO954667D0 (de)
NZ (1) NZ322619A (de)
PT (2) PT868529E (de)
WO (1) WO1997019191A1 (de)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9715034D0 (en) * 1997-07-18 1997-09-24 Zeneca Ltd Assay
JP4794052B2 (ja) * 1999-04-09 2011-10-12 ジェンザイム・コーポレーション 癌の指標である核酸を検出するための方法
US6531302B1 (en) * 1999-04-12 2003-03-11 Nanogen/Becton Dickinson Partnership Anchored strand displacement amplification on an electronically addressable microchip
US6849403B1 (en) 1999-09-08 2005-02-01 Exact Sciences Corporation Apparatus and method for drug screening
US6586177B1 (en) 1999-09-08 2003-07-01 Exact Sciences Corporation Methods for disease detection
US7368233B2 (en) * 1999-12-07 2008-05-06 Exact Sciences Corporation Methods of screening for lung neoplasm based on stool samples containing a nucleic acid marker indicative of a neoplasm
US6605451B1 (en) * 2000-06-06 2003-08-12 Xtrana, Inc. Methods and devices for multiplexing amplification reactions
EP2351853A1 (de) * 2000-06-06 2011-08-03 Life Technologies Corporation Methode und Vorrichtungen für multiplex Amplifizierungsreaktionen
US7087414B2 (en) 2000-06-06 2006-08-08 Applera Corporation Methods and devices for multiplexing amplification reactions
US7482116B2 (en) 2002-06-07 2009-01-27 Dna Genotek Inc. Compositions and methods for obtaining nucleic acids from sputum
EP1594975A4 (de) * 2002-12-04 2006-08-02 Applera Corp Multiplex-amplifikation von polynukleotiden
WO2005113769A1 (en) * 2004-05-14 2005-12-01 Exact Sciences Corporation Method for stabilizing biological samples for nucleic acid analysis
US20070134709A1 (en) * 2005-12-14 2007-06-14 Xiping Xu Usages of MTHFR gene polymorphisms in predicting homocysteine level, disease risk, and treatment effects and related methods and kit
GB2435512A (en) 2006-02-23 2007-08-29 Mologic Ltd A binding assay and assay device
CN103424541B (zh) 2006-05-18 2018-01-30 分子压型学会股份有限公司 确定针对病状的个性化医疗介入的系统和方法
US8768629B2 (en) 2009-02-11 2014-07-01 Caris Mpi, Inc. Molecular profiling of tumors
US8583380B2 (en) 2008-09-05 2013-11-12 Aueon, Inc. Methods for stratifying and annotating cancer drug treatment options
CN107254538A (zh) 2008-11-12 2017-10-17 卡里斯生命科学瑞士控股有限责任公司 使用外来体来确定表现型的方法和系统
US20130005598A1 (en) * 2009-12-31 2013-01-03 The Regents Of The University Of Michigan Methods for Diagnosing The Malignant Potential of Pancreatic Cystic Lesions
KR20130056855A (ko) 2010-03-01 2013-05-30 카리스 라이프 사이언스 룩셈부르크 홀딩스 치료진단용 생물학적 지표들
KR20130043104A (ko) 2010-04-06 2013-04-29 카리스 라이프 사이언스 룩셈부르크 홀딩스 질병용 순환 생물학적 지표들
CN103228798B (zh) 2010-09-24 2015-12-09 斯坦福大学托管董事会 使用固定的引物直接捕获、扩增及测序靶标dna
GB201107466D0 (en) 2011-05-05 2011-06-15 Loktionov Alexandre Device and method for non-invasive collection of colorectal mucocellular layer and disease detection
CN102796811B (zh) * 2011-05-26 2013-12-18 上海赛安生物医药科技有限公司 检测kras突变的试剂及方法
AU2012273121B2 (en) 2011-06-19 2016-08-25 Abogen, Inc. Devices, solutions and methods for sample collection
US9637796B2 (en) * 2011-11-17 2017-05-02 The Johns Hopkins University Differential identification of pancreatic cysts
MX2015006757A (es) * 2012-11-30 2015-11-30 Applied Proteomics Inc Método para la evaluación de la presencia de o riesgo de tumores de colon.
SG11201607364RA (en) 2014-03-07 2016-10-28 Dna Genotek Inc Composition and method for stabilizing nucleic acids in biological samples
EP3281016A1 (de) 2015-04-10 2018-02-14 Applied Proteomics Inc. Proteinbiomarkertafeln zur detektion von kolorektalkrebs und fortgeschrittenem adenom
US10753936B2 (en) 2016-07-22 2020-08-25 Van Andel Research Institute Method of detecting the level of a glycan
EP3810182A4 (de) 2018-06-19 2022-08-24 BioNTech US Inc. Neoantigene und ihre verwendungen

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4871838A (en) * 1985-07-23 1989-10-03 The Board Of Rijks Universiteit Leiden Probes and methods for detecting activated ras oncogenes
US5137806A (en) * 1989-12-11 1992-08-11 Board Of Regents, The University Of Texas System Methods and compositions for the detection of sequences in selected DNA molecules
IL97222A (en) * 1990-02-16 1995-08-31 Orion Yhtymae Oy Method and reagent for determining specific nucleotide variations
EP0672181B1 (de) 1992-04-01 2003-11-05 The Johns Hopkins University School Of Medicine Verfahren zur bestimmung von säugetier nukleinsäuren aus stuhlproben und dafür benötigte reagenzien
ATE198358T1 (de) * 1992-04-27 2001-01-15 Dartmouth College Detektion von gensequenzen in biologischen flüssigkeiten
JPH06167492A (ja) * 1992-11-30 1994-06-14 Otsuka Pharmaceut Co Ltd 変異癌遺伝子の検出測定方法
DE19512369A1 (de) * 1995-04-01 1996-10-02 Boehringer Mannheim Gmbh Vorrichtung zur Isolierung von Nukleinsäuren

Also Published As

Publication number Publication date
NO982246D0 (no) 1998-05-15
AU7656996A (en) 1997-06-11
AU723980C (en) 2002-10-24
EP1394272B1 (de) 2006-03-01
PT1394272E (pt) 2006-07-31
WO1997019191A1 (en) 1997-05-29
DE69630234T2 (de) 2004-08-19
ES2262930T3 (es) 2006-12-01
JP2000500346A (ja) 2000-01-18
EP0868529B1 (de) 2003-10-01
NO324963B1 (no) 2008-01-14
DE69635848D1 (de) 2006-04-27
DE69630234D1 (de) 2003-11-06
EP1394272A1 (de) 2004-03-03
ATE251222T1 (de) 2003-10-15
DK1394272T3 (da) 2006-07-03
NZ322619A (en) 1999-04-29
PT868529E (pt) 2004-02-27
ES2208766T3 (es) 2004-06-16
DE69635848T2 (de) 2006-11-30
US6440661B1 (en) 2002-08-27
EP0868529A1 (de) 1998-10-07
AU723980B2 (en) 2000-09-07
DK0868529T3 (da) 2004-02-02
NO982246L (no) 1998-07-07
NO954667D0 (no) 1995-11-17

Similar Documents

Publication Publication Date Title
ATE318934T1 (de) Verfahren zum nachweis von ki-ras mutationen
ATE191513T1 (de) Verfahren zur amplifikation von nukleinsäuren
DE3486254D1 (de) Verfahren zum aufspüren, identifizieren und quantifizieren von organismen und viren.
ATE121794T1 (de) Verfahren zum nachweis des karzinogenen menschlichen papillomavirus.
DE59310167D1 (de) Verfahren zum Nachweis und zur Bestimmung von Mediatoren
DE68924779D1 (de) Vorrichtung und verfahren zum nachweis von chemischen spezies.
DK0518650T3 (da) Sekvensspecifik DNA-binding med p53
DE69636895D1 (de) Die Verwendung der 3'-wesentlichen Bearbeitungswirksamkeit von DNS-Polymerase
DE69936532D1 (de) Verfahren zum quantitativen nachweis von nukleinsäuren
ATE454468T1 (de) Nachweis der instabilität von mikrosatelliten und verwendung davon bei der tumordiagnose
DE69120936D1 (de) Genetischer test für zytochrom-p450
DE69929882D1 (de) Verfahren und vorrichtung zur nukleinsäurereinigung
ATE56990T1 (de) Verfahren und reagenz zur bestimmung von gesamt- bilirubin.
ATE170561T1 (de) Methode und zusammensetzungen zur behandlung von bösartigen entartungen, die in zusammenhang mit einer proteinkinase stehen
ATE142689T1 (de) Verfahren zur herstellung von aktiviertem protein c
AU2283792A (en) Direct detection of hepatitis c virus rna
DE69531505D1 (de) Verfahren zur zellerkennung
DE59107264D1 (de) Verfahren zur Detektion und quantitativen Bestimmung von Nitrosomonas-Stämmen in Abwässern oder Boden
DE69712549D1 (de) Verfahren zur Herstellung von Peroxiperfluoropolyethern
DE59106112D1 (de) Verfahren zur Inaktivierung der biologischen Aktivität von DNA.
NO992666L (no) ICAM-4 og diagnostisk anvendelse av denne
GB2256271A (en) Genetic assay for cytochrome p450
DE3865707D1 (de) Zusammensetzungen, bestimmt zur holzbehandlung und verfahren zur holzbehandlung.

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification

Ref document number: 1394272

Country of ref document: EP

REN Ceased due to non-payment of the annual fee