ATE318934T1 - Verfahren zum nachweis von ki-ras mutationen - Google Patents
Verfahren zum nachweis von ki-ras mutationenInfo
- Publication number
- ATE318934T1 ATE318934T1 AT03020560T AT03020560T ATE318934T1 AT E318934 T1 ATE318934 T1 AT E318934T1 AT 03020560 T AT03020560 T AT 03020560T AT 03020560 T AT03020560 T AT 03020560T AT E318934 T1 ATE318934 T1 AT E318934T1
- Authority
- AT
- Austria
- Prior art keywords
- detecting
- ras mutations
- pcr
- tissue
- allele specific
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/118—Prognosis of disease development
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/156—Polymorphic or mutational markers
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Analytical Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Pathology (AREA)
- Genetics & Genomics (AREA)
- Immunology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Hospice & Palliative Care (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Oncology (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Analysing Materials By The Use Of Radiation (AREA)
- Holo Graphy (AREA)
- Saccharide Compounds (AREA)
- Diaphragms For Electromechanical Transducers (AREA)
- Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Control And Other Processes For Unpacking Of Materials (AREA)
- Electrophonic Musical Instruments (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Electrically Operated Instructional Devices (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
NO954667A NO954667D0 (no) | 1995-11-17 | 1995-11-17 | Fremgangsmåte til deteksjon av Ki-ras mutasjoner |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE318934T1 true ATE318934T1 (de) | 2006-03-15 |
Family
ID=19898772
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT03020560T ATE318934T1 (de) | 1995-11-17 | 1996-11-15 | Verfahren zum nachweis von ki-ras mutationen |
AT96939373T ATE251222T1 (de) | 1995-11-17 | 1996-11-15 | Verfahren zur bestimung von ki-ras mutationen und dieses leistender testsatz |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT96939373T ATE251222T1 (de) | 1995-11-17 | 1996-11-15 | Verfahren zur bestimung von ki-ras mutationen und dieses leistender testsatz |
Country Status (12)
Country | Link |
---|---|
US (1) | US6440661B1 (de) |
EP (2) | EP0868529B1 (de) |
JP (1) | JP2000500346A (de) |
AT (2) | ATE318934T1 (de) |
AU (1) | AU723980C (de) |
DE (2) | DE69635848T2 (de) |
DK (2) | DK1394272T3 (de) |
ES (2) | ES2262930T3 (de) |
NO (2) | NO954667D0 (de) |
NZ (1) | NZ322619A (de) |
PT (2) | PT868529E (de) |
WO (1) | WO1997019191A1 (de) |
Families Citing this family (29)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9715034D0 (en) * | 1997-07-18 | 1997-09-24 | Zeneca Ltd | Assay |
US6964846B1 (en) * | 1999-04-09 | 2005-11-15 | Exact Sciences Corporation | Methods for detecting nucleic acids indicative of cancer |
US6531302B1 (en) * | 1999-04-12 | 2003-03-11 | Nanogen/Becton Dickinson Partnership | Anchored strand displacement amplification on an electronically addressable microchip |
US6586177B1 (en) | 1999-09-08 | 2003-07-01 | Exact Sciences Corporation | Methods for disease detection |
AU4714201A (en) * | 1999-12-07 | 2001-06-18 | Exact Sciences Corporation | Supracolonic aerodigestive neoplasm detection |
US6605451B1 (en) * | 2000-06-06 | 2003-08-12 | Xtrana, Inc. | Methods and devices for multiplexing amplification reactions |
EP2351853A1 (de) * | 2000-06-06 | 2011-08-03 | Life Technologies Corporation | Methode und Vorrichtungen für multiplex Amplifizierungsreaktionen |
US7087414B2 (en) | 2000-06-06 | 2006-08-08 | Applera Corporation | Methods and devices for multiplexing amplification reactions |
US7482116B2 (en) | 2002-06-07 | 2009-01-27 | Dna Genotek Inc. | Compositions and methods for obtaining nucleic acids from sputum |
AU2003298706A1 (en) | 2002-12-04 | 2004-06-23 | Applera Corporation | Multiplex amplification of polynucleotides |
WO2005113769A1 (en) * | 2004-05-14 | 2005-12-01 | Exact Sciences Corporation | Method for stabilizing biological samples for nucleic acid analysis |
US20070134709A1 (en) * | 2005-12-14 | 2007-06-14 | Xiping Xu | Usages of MTHFR gene polymorphisms in predicting homocysteine level, disease risk, and treatment effects and related methods and kit |
GB2435512A (en) | 2006-02-23 | 2007-08-29 | Mologic Ltd | A binding assay and assay device |
RU2008146868A (ru) | 2006-05-18 | 2010-06-27 | Кэрис МПИ, Инк.445 Норт Фифс Стрит, 3-ий Флор, Феникс, Аризона 85004, США (US) | Система и способ определения персонализированого медицинского вмешательства при болезненном состоянии |
US8768629B2 (en) | 2009-02-11 | 2014-07-01 | Caris Mpi, Inc. | Molecular profiling of tumors |
EP3216874A1 (de) | 2008-09-05 | 2017-09-13 | TOMA Biosciences, Inc. | Verfahren zum stratifizieren und annotieren der behandlungsoptionen eines krebsmedikaments |
CN102301002A (zh) | 2008-11-12 | 2011-12-28 | 卡里斯生命科学卢森堡控股有限责任公司 | 使用外来体来确定表现型的方法和系统 |
WO2011082321A1 (en) * | 2009-12-31 | 2011-07-07 | Van Andel Research Institute | Methods for diagnosing the malignant potential of pancreatic cystic lesions |
JP5808349B2 (ja) | 2010-03-01 | 2015-11-10 | カリス ライフ サイエンシズ スウィッツァーランド ホールディングスゲーエムベーハー | セラノーシスのためのバイオマーカー |
US9469876B2 (en) | 2010-04-06 | 2016-10-18 | Caris Life Sciences Switzerland Holdings Gmbh | Circulating biomarkers for metastatic prostate cancer |
EP3572528A1 (de) | 2010-09-24 | 2019-11-27 | The Board of Trustees of the Leland Stanford Junior University | Direkte erfassung, amplifikation und sequenzierung einer ziel-dna unter verwendung immobilisierter primer |
GB201107466D0 (en) | 2011-05-05 | 2011-06-15 | Loktionov Alexandre | Device and method for non-invasive collection of colorectal mucocellular layer and disease detection |
CN102796811B (zh) * | 2011-05-26 | 2013-12-18 | 上海赛安生物医药科技有限公司 | 检测kras突变的试剂及方法 |
WO2012177656A2 (en) | 2011-06-19 | 2012-12-27 | Abogen, Inc. | Devices, solutions and methods for sample collection |
JP5947392B2 (ja) * | 2011-11-17 | 2016-07-06 | ザ ジョンズ ホプキンス ユニバーシティー | 膵嚢胞の鑑別 |
CN110596385A (zh) * | 2012-11-30 | 2019-12-20 | 迪森德克斯公司 | 用于评估结肠肿瘤的存在或风险的方法 |
ES2880310T3 (es) | 2014-03-07 | 2021-11-24 | Dna Genotek Inc | Composición y método para estabilizar ácidos nucleicos en muestras biológicas |
US9689874B2 (en) | 2015-04-10 | 2017-06-27 | Applied Proteomics, Inc. | Protein biomarker panels for detecting colorectal cancer and advanced adenoma |
US10753936B2 (en) | 2016-07-22 | 2020-08-25 | Van Andel Research Institute | Method of detecting the level of a glycan |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4871838A (en) * | 1985-07-23 | 1989-10-03 | The Board Of Rijks Universiteit Leiden | Probes and methods for detecting activated ras oncogenes |
US5137806A (en) * | 1989-12-11 | 1992-08-11 | Board Of Regents, The University Of Texas System | Methods and compositions for the detection of sequences in selected DNA molecules |
IL97222A (en) * | 1990-02-16 | 1995-08-31 | Orion Yhtymae Oy | Method and Responder for Determining Special Changes to Nucleotide |
WO1993020235A1 (en) | 1992-04-01 | 1993-10-14 | The Johns Hopkins University School Of Medicine | Methods of detecting mammalian nucleic acids isolated from stool specimen and reagents therefor |
WO1993022456A1 (en) * | 1992-04-27 | 1993-11-11 | Trustees Of Dartmouth College | Detection of gene sequences in biological fluids |
JPH06167492A (ja) * | 1992-11-30 | 1994-06-14 | Otsuka Pharmaceut Co Ltd | 変異癌遺伝子の検出測定方法 |
DE19512369A1 (de) * | 1995-04-01 | 1996-10-02 | Boehringer Mannheim Gmbh | Vorrichtung zur Isolierung von Nukleinsäuren |
-
1995
- 1995-11-17 NO NO954667A patent/NO954667D0/no unknown
-
1996
- 1996-11-15 DE DE69635848T patent/DE69635848T2/de not_active Expired - Fee Related
- 1996-11-15 NZ NZ322619A patent/NZ322619A/xx unknown
- 1996-11-15 ES ES03020560T patent/ES2262930T3/es not_active Expired - Lifetime
- 1996-11-15 PT PT96939373T patent/PT868529E/pt unknown
- 1996-11-15 US US09/068,805 patent/US6440661B1/en not_active Expired - Fee Related
- 1996-11-15 AU AU76569/96A patent/AU723980C/en not_active Ceased
- 1996-11-15 EP EP96939373A patent/EP0868529B1/de not_active Expired - Lifetime
- 1996-11-15 AT AT03020560T patent/ATE318934T1/de not_active IP Right Cessation
- 1996-11-15 AT AT96939373T patent/ATE251222T1/de not_active IP Right Cessation
- 1996-11-15 EP EP03020560A patent/EP1394272B1/de not_active Expired - Lifetime
- 1996-11-15 DK DK03020560T patent/DK1394272T3/da active
- 1996-11-15 DE DE69630234T patent/DE69630234T2/de not_active Expired - Fee Related
- 1996-11-15 JP JP9519622A patent/JP2000500346A/ja active Pending
- 1996-11-15 WO PCT/NO1996/000271 patent/WO1997019191A1/en active IP Right Grant
- 1996-11-15 ES ES96939373T patent/ES2208766T3/es not_active Expired - Lifetime
- 1996-11-15 DK DK96939373T patent/DK0868529T3/da active
- 1996-11-15 PT PT03020560T patent/PT1394272E/pt unknown
-
1998
- 1998-05-15 NO NO19982246A patent/NO324963B1/no not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
AU723980C (en) | 2002-10-24 |
AU7656996A (en) | 1997-06-11 |
EP0868529A1 (de) | 1998-10-07 |
PT1394272E (pt) | 2006-07-31 |
EP0868529B1 (de) | 2003-10-01 |
NZ322619A (en) | 1999-04-29 |
PT868529E (pt) | 2004-02-27 |
ES2262930T3 (es) | 2006-12-01 |
JP2000500346A (ja) | 2000-01-18 |
DE69635848T2 (de) | 2006-11-30 |
DE69630234T2 (de) | 2004-08-19 |
EP1394272A1 (de) | 2004-03-03 |
NO324963B1 (no) | 2008-01-14 |
DE69635848D1 (de) | 2006-04-27 |
EP1394272B1 (de) | 2006-03-01 |
US6440661B1 (en) | 2002-08-27 |
NO954667D0 (no) | 1995-11-17 |
NO982246L (no) | 1998-07-07 |
DE69630234D1 (de) | 2003-11-06 |
NO982246D0 (no) | 1998-05-15 |
DK0868529T3 (da) | 2004-02-02 |
ES2208766T3 (es) | 2004-06-16 |
ATE251222T1 (de) | 2003-10-15 |
WO1997019191A1 (en) | 1997-05-29 |
DK1394272T3 (da) | 2006-07-03 |
AU723980B2 (en) | 2000-09-07 |
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Legal Events
Date | Code | Title | Description |
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UEP | Publication of translation of european patent specification |
Ref document number: 1394272 Country of ref document: EP |
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REN | Ceased due to non-payment of the annual fee |