ES2184408T3 - Sistema transdermico que contiene un antioxidante. - Google Patents
Sistema transdermico que contiene un antioxidante.Info
- Publication number
- ES2184408T3 ES2184408T3 ES99902525T ES99902525T ES2184408T3 ES 2184408 T3 ES2184408 T3 ES 2184408T3 ES 99902525 T ES99902525 T ES 99902525T ES 99902525 T ES99902525 T ES 99902525T ES 2184408 T3 ES2184408 T3 ES 2184408T3
- Authority
- ES
- Spain
- Prior art keywords
- antioxidant
- system containing
- transdermal system
- ethyl
- carbamate
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000003963 antioxidant agent Substances 0.000 title abstract 2
- 230000003078 antioxidant effect Effects 0.000 title abstract 2
- 229940100640 transdermal system Drugs 0.000 title 1
- 229940126062 Compound A Drugs 0.000 abstract 1
- NLDMNSXOCDLTTB-UHFFFAOYSA-N Heterophylliin A Natural products O1C2COC(=O)C3=CC(O)=C(O)C(O)=C3C3=C(O)C(O)=C(O)C=C3C(=O)OC2C(OC(=O)C=2C=C(O)C(O)=C(O)C=2)C(O)C1OC(=O)C1=CC(O)=C(O)C(O)=C1 NLDMNSXOCDLTTB-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 abstract 1
- 239000012458 free base Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
- A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
- A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
- A61K9/7061—Polyacrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/27—Esters, e.g. nitroglycerine, selenocyanates of carbamic or thiocarbamic acids, meprobamate, carbachol, neostigmine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Dermatology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Emergency Medicine (AREA)
- Neurology (AREA)
- General Chemical & Material Sciences (AREA)
- Hospice & Palliative Care (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Psychiatry (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Food Preservation Except Freezing, Refrigeration, And Drying (AREA)
- Anti-Oxidant Or Stabilizer Compositions (AREA)
- Fats And Perfumes (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Compositions Of Macromolecular Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Dental Preparations (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
Una composición farmacéutica que comprende (S)-N- etil-3-[(1-dimetilamino)etil]-N-metil-fenil-carbamato (Compuesto A) en forma de base libre o de sal de adición de ácido y un antioxidante.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9800526.7A GB9800526D0 (en) | 1998-01-12 | 1998-01-12 | Organic compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2184408T3 true ES2184408T3 (es) | 2003-04-01 |
Family
ID=10825116
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES99902525T Expired - Lifetime ES2184408T3 (es) | 1998-01-12 | 1999-01-08 | Sistema transdermico que contiene un antioxidante. |
Country Status (25)
| Country | Link |
|---|---|
| US (1) | US6335031B1 (es) |
| EP (1) | EP1047409B1 (es) |
| KR (1) | KR100569051B1 (es) |
| CN (1) | CN1129427C (es) |
| AT (1) | ATE223711T1 (es) |
| AU (1) | AU745661B2 (es) |
| BR (1) | BR9906920A (es) |
| CA (1) | CA2315784C (es) |
| CZ (1) | CZ300598B6 (es) |
| DE (1) | DE69902875T2 (es) |
| DK (1) | DK1047409T3 (es) |
| ES (1) | ES2184408T3 (es) |
| GB (1) | GB9800526D0 (es) |
| HU (1) | HU227159B1 (es) |
| ID (1) | ID27503A (es) |
| IL (1) | IL137100A (es) |
| MX (1) | MXPA00006438A (es) |
| NO (1) | NO328390B1 (es) |
| NZ (1) | NZ505650A (es) |
| PL (1) | PL201328B1 (es) |
| PT (1) | PT1047409E (es) |
| RU (1) | RU2219926C2 (es) |
| SK (1) | SK284622B6 (es) |
| TR (2) | TR200001688T2 (es) |
| WO (1) | WO1999034782A1 (es) |
Families Citing this family (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR100603900B1 (ko) | 1998-10-01 | 2006-07-25 | 노파르티스 아게 | 신규의 서방성 경구 제제 |
| FR2793689B1 (fr) * | 1999-05-19 | 2001-08-24 | Pf Medicament | Dispositif transdermique pour l'administration de testosterone ou d'un de ses derives |
| PL198323B1 (pl) * | 1999-11-29 | 2008-06-30 | Lohmann Therapie Syst Lts | Transdermalny system terapeutyczny zawierający wrażliwe na utlenianie substancje czynne i sposób jego wytwarzania |
| DE10107663B4 (de) * | 2001-02-19 | 2004-09-09 | Lts Lohmann Therapie-Systeme Ag | Testosteronhaltiges transdermales therapeutisches System, Verfahren zu seiner Herstellung und seine Verwendung |
| ITMI20020798A1 (it) * | 2002-04-15 | 2003-10-15 | F T Holding S A | Cerotti transdermici a matrice adesiva siliconica stabilizzati con copolimeri metacrilici |
| FR2881653A1 (fr) * | 2005-02-04 | 2006-08-11 | Frederic Khodja | Dispositif permettant l'administration en continu d'une dose physiologique controlee d'au moins un mineral ou une vitamine |
| TWI389709B (zh) * | 2005-12-01 | 2013-03-21 | Novartis Ag | 經皮治療系統 |
| WO2009022345A1 (en) * | 2007-08-14 | 2009-02-19 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Phenyl carbamates for the treatment of multiple sclerosis |
| PE20141585A1 (es) | 2008-07-28 | 2014-11-13 | Takeda Pharmaceutical | Composicion farmaceutica estabilizada a base de un compuesto no petidico |
| US20100087768A1 (en) * | 2008-10-02 | 2010-04-08 | Forlano Paula | Transdermal drug delivery system for liquid active ingredient |
| US10076502B2 (en) | 2009-12-22 | 2018-09-18 | Luye Pharma Ag | Transdermal therapeutic system for administering rivastigmine or derivatives thereof |
| PL2515886T3 (pl) | 2009-12-22 | 2018-08-31 | Luye Pharma Ag | Przezskórny układ terapeutyczny do podawania rywastygminy lub jej pochodnych |
| ES2363395B1 (es) * | 2010-01-20 | 2012-02-23 | Farmalider, S.A. | Composición farmacéutica l�?quida de rivastigmina o de una de sus sales de adición de �?cido para la administración por v�?a oral. |
| WO2011151359A1 (en) | 2010-06-02 | 2011-12-08 | Noscira, S.A. | Combined treatment with a cholinesterase inhibitor and a thiadiazolidinedione derivative |
| DE102010026903A1 (de) | 2010-07-12 | 2012-01-12 | Amw Gmbh | Transdermales therapeutisches System mit Avocadoöl oder Palmöl als Hilfsstoff |
| SG10201505658RA (en) | 2010-07-21 | 2015-09-29 | 3M Innovative Properties Co | Transdermal adhesive compositions, devices, and methods |
| SI2468274T1 (sl) | 2010-12-14 | 2015-10-30 | Acino Ag | Transdermalni terapevtski sistem za dajanje aktivne snovi |
| KR101788802B1 (ko) * | 2010-12-24 | 2017-10-20 | 주식회사 삼양바이오팜 | 리바스티그민을 함유하는 경피흡수제제 |
| KR20120126898A (ko) * | 2011-05-13 | 2012-11-21 | 에스케이케미칼주식회사 | 리바스티그민 또는 이의 염을 함유하는 경피 투여 조성물 |
| WO2012161489A2 (ko) | 2011-05-20 | 2012-11-29 | 에스케이케미칼 주식회사 | 리바스티그민 함유 패취 |
| KR20120130073A (ko) * | 2011-05-20 | 2012-11-28 | 에스케이케미칼주식회사 | 리바스티그민 함유 패취 |
| EP2594261A1 (en) | 2011-11-18 | 2013-05-22 | Labtec GmbH | Composition for transdermal administration of rivastigmine |
| DE102012000369A1 (de) | 2012-01-11 | 2013-07-11 | Alfred E. Tiefenbacher (Gmbh & Co. Kg) | Transdermales therapeutisches System mit Cholinesterase-Hemmer |
| WO2013142339A1 (en) | 2012-03-23 | 2013-09-26 | Novartis Ag | Transdermal therapeutic system and method |
| PL2859892T3 (pl) | 2012-06-12 | 2023-10-16 | KM Transderm Ltd. | Plaster |
| CA2883930A1 (en) * | 2012-09-03 | 2014-03-06 | Nipro Patch Co., Ltd. | Adhesive skin patch |
| KR20140038237A (ko) | 2012-09-20 | 2014-03-28 | 에스케이케미칼주식회사 | 리바스티그민의 안정성이 개선된 의약품 |
| WO2014051128A1 (ja) | 2012-09-28 | 2014-04-03 | 株式会社 ケイ・エム トランスダーム | 貼付剤 |
| WO2014111790A2 (en) | 2013-01-15 | 2014-07-24 | Zydus Technologies Limited | Stable transdermal pharmaceutical drug delivery system comprising rivastigmine |
| CN106413695B (zh) * | 2014-04-08 | 2019-12-10 | 帝国制药美国公司 | 利伐斯的明透皮组合物及其使用方法 |
| JPWO2015174502A1 (ja) | 2014-05-15 | 2017-05-25 | ニチバン株式会社 | リバスチグミンを含有する貼付剤のための包装体 |
| KR102710072B1 (ko) | 2018-08-31 | 2024-09-24 | 에스케이케미칼 주식회사 | 장기 투여용 리바스티그민 패취 |
| KR102823139B1 (ko) | 2018-08-31 | 2025-06-19 | 에스케이케미칼 주식회사 | 장기 투여용 리바스티그민 패취 |
| TW202140017A (zh) * | 2020-02-19 | 2021-11-01 | 日商大日本住友製藥股份有限公司 | 經皮吸收製劑 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL195004C (nl) * | 1987-03-04 | 2003-11-04 | Novartis Ag | Fenylcarbamaat bevattend farmaceutisch preparaat. |
| GB9213322D0 (en) * | 1992-06-23 | 1992-08-05 | Efamol Holdings | Antioxidant compositions |
| AU5716898A (en) * | 1997-01-08 | 1998-08-03 | Warner-Lambert Company | Acetylcholinesterase inhibitors in combination with muscarinic agonists for the treatment of alzheimer's disease |
| DE69802498T2 (de) * | 1997-01-17 | 2002-07-04 | Takeda Chemical Industries, Ltd. | Idebenon enthaltendes kombinationspräparat zur alzheimer behandlung |
-
1998
- 1998-01-12 GB GBGB9800526.7A patent/GB9800526D0/en not_active Ceased
-
1999
- 1999-01-08 DK DK99902525T patent/DK1047409T3/da active
- 1999-01-08 RU RU2000120951/15A patent/RU2219926C2/ru active
- 1999-01-08 NZ NZ505650A patent/NZ505650A/xx not_active IP Right Cessation
- 1999-01-08 TR TR2000/01688T patent/TR200001688T2/xx unknown
- 1999-01-08 CA CA002315784A patent/CA2315784C/en not_active Expired - Lifetime
- 1999-01-08 TR TR2001/01021T patent/TR200101021T2/xx unknown
- 1999-01-08 ID IDW20001301A patent/ID27503A/id unknown
- 1999-01-08 IL IL13710099A patent/IL137100A/en not_active IP Right Cessation
- 1999-01-08 MX MXPA00006438A patent/MXPA00006438A/es active IP Right Grant
- 1999-01-08 AU AU22785/99A patent/AU745661B2/en not_active Expired
- 1999-01-08 ES ES99902525T patent/ES2184408T3/es not_active Expired - Lifetime
- 1999-01-08 SK SK1053-2000A patent/SK284622B6/sk not_active IP Right Cessation
- 1999-01-08 KR KR1020007006433A patent/KR100569051B1/ko not_active Ceased
- 1999-01-08 HU HU0004300A patent/HU227159B1/hu unknown
- 1999-01-08 EP EP99902525A patent/EP1047409B1/en not_active Expired - Lifetime
- 1999-01-08 PT PT99902525T patent/PT1047409E/pt unknown
- 1999-01-08 PL PL341347A patent/PL201328B1/pl unknown
- 1999-01-08 BR BR9906920-2A patent/BR9906920A/pt not_active Application Discontinuation
- 1999-01-08 DE DE69902875T patent/DE69902875T2/de not_active Expired - Lifetime
- 1999-01-08 CN CN99802092A patent/CN1129427C/zh not_active Expired - Lifetime
- 1999-01-08 AT AT99902525T patent/ATE223711T1/de active
- 1999-01-08 CZ CZ20002557A patent/CZ300598B6/cs not_active IP Right Cessation
- 1999-01-08 WO PCT/EP1999/000078 patent/WO1999034782A1/en not_active Ceased
- 1999-04-14 US US09/291,498 patent/US6335031B1/en not_active Expired - Lifetime
-
2000
- 2000-07-05 NO NO20003472A patent/NO328390B1/no not_active IP Right Cessation
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