ES2182139T3 - Dispersiones acuosas estables y polvos en seco, dispersables en agua estables de xantofilas, su obtencion y empleo. - Google Patents

Dispersiones acuosas estables y polvos en seco, dispersables en agua estables de xantofilas, su obtencion y empleo.

Info

Publication number
ES2182139T3
ES2182139T3 ES97952027T ES97952027T ES2182139T3 ES 2182139 T3 ES2182139 T3 ES 2182139T3 ES 97952027 T ES97952027 T ES 97952027T ES 97952027 T ES97952027 T ES 97952027T ES 2182139 T3 ES2182139 T3 ES 2182139T3
Authority
ES
Spain
Prior art keywords
water
stainable
dry powder
stable
mixture
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES97952027T
Other languages
English (en)
Inventor
Helmut Auweter
Heribert Bohn
Erik Luddecke
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
BASF SE
Original Assignee
BASF SE
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by BASF SE filed Critical BASF SE
Application granted granted Critical
Publication of ES2182139T3 publication Critical patent/ES2182139T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C403/00—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone
    • C07C403/24—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by six-membered non-aromatic rings, e.g. beta-carotene
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A23K20/179—Colouring agents, e.g. pigmenting or dyeing agents
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L5/00—Preparation or treatment of foods or foodstuffs, in general; Food or foodstuffs obtained thereby; Materials therefor
    • A23L5/40—Colouring or decolouring of foods
    • A23L5/42—Addition of dyes or pigments, e.g. in combination with optical brighteners
    • A23L5/43—Addition of dyes or pigments, e.g. in combination with optical brighteners using naturally occurring organic dyes or pigments, their artificial duplicates or their derivatives
    • A23L5/44—Addition of dyes or pigments, e.g. in combination with optical brighteners using naturally occurring organic dyes or pigments, their artificial duplicates or their derivatives using carotenoids or xanthophylls
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/047—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates having two or more hydroxy groups, e.g. sorbitol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/12—Ketones
    • A61K31/122—Ketones having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
    • C09B61/00—Dyes of natural origin prepared from natural sources, e.g. vegetable sources
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
    • C09B67/00—Influencing the physical, e.g. the dyeing or printing properties of dyestuffs without chemical reactions, e.g. by treating with solvents grinding or grinding assistants, coating of pigments or dyes; Process features in the making of dyestuff preparations; Dyestuff preparations of a special physical nature, e.g. tablets, films
    • C09B67/0071—Process features in the making of dyestuff preparations; Dehydrating agents; Dispersing agents; Dustfree compositions
    • C09B67/0084—Dispersions of dyes
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
    • C09B67/00—Influencing the physical, e.g. the dyeing or printing properties of dyestuffs without chemical reactions, e.g. by treating with solvents grinding or grinding assistants, coating of pigments or dyes; Process features in the making of dyestuff preparations; Dyestuff preparations of a special physical nature, e.g. tablets, films
    • C09B67/0071—Process features in the making of dyestuff preparations; Dehydrating agents; Dispersing agents; Dustfree compositions
    • C09B67/0084—Dispersions of dyes
    • C09B67/0091—Process features in the making of dispersions, e.g. ultrasonics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Polymers & Plastics (AREA)
  • Dispersion Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Food Science & Technology (AREA)
  • Animal Husbandry (AREA)
  • Nutrition Science (AREA)
  • Zoology (AREA)
  • Fodder In General (AREA)
  • Medicinal Preparation (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Colloid Chemistry (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • General Preparation And Processing Of Foods (AREA)
  • Glanulating (AREA)
  • Cosmetics (AREA)
  • Paints Or Removers (AREA)
  • Processes Of Treating Macromolecular Substances (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

EN UN PROCEDIMIENTO PARA PRODUCIR UNA DISPERSION ACUOSA ESTABLE O UN POLVO XANTOFILO SECO, ESTABLE Y DISPERSABLE EN AGUA: (A) UNA SOLUCION DISPERSA MOLECULAR DE AL MENOS UN XANTOFILO, SI ES PRECISO JUNTO CON UN EMULSIONANTE Y/O UN ACEITE COMESTIBLE, SE PRODUCE EN UN DISOLVENTE ORGANICO MISCIBLE EN AGUA, O EN UNA MEZCLA DE AGUA Y UN DISOLVENTE ORGANICO MISCIBLE EN AGUA, A TEMPERATURAS SUPERIORES A 30 C; (B) ESTA SOLUCION SE MEZCLA CON UNA SOLUCION ACUOSA DE UNA MEZCLA DE COLOIDES PROTECTORES; (B1) CONTENIENDO LA MEZCLA AL MENOS UN COMPONENTE COLOIDAL PROTECTOR DE BAJO PESO MOLECULAR Y AL MENOS UN COMPONENTE COLOIDAL PROTECTOR DE ELEVADO PESO MOLECULAR, CUYOS PESOS MOLECULARES DIFIEREN EN UN MINIMO DE 10.000; (B2) CONVIRTIENDOSE EL COMPONENTE DISOLVENTE EN LA FASE ACUOSA, Y PRODUCIENDOSE LA FASE HIDROFOBA DEL XANTOFILO COMO FASE NANODISPERSADA; Y (C) SI SE REQUIERE, LA DISPERSION ASI OBTENIDA SE LIBERA DEL DISOLVENTE Y DEL AGUA A FIN DE PRODUCIR UN POLVO SECO DISPERSABLE EN AGUA SECANDOSE, SIES PRECISO, EN PRESENCIA DE UN MATERIAL DE REVESTIMIENTO.
ES97952027T 1996-12-12 1997-12-01 Dispersiones acuosas estables y polvos en seco, dispersables en agua estables de xantofilas, su obtencion y empleo. Expired - Lifetime ES2182139T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19651681A DE19651681A1 (de) 1996-12-12 1996-12-12 Stabile, wäßrige Dispersionen und stabile, wasserdispergierbare Trockenpulver von Xanthopyllen, deren Herstellung und Verwendung

Publications (1)

Publication Number Publication Date
ES2182139T3 true ES2182139T3 (es) 2003-03-01

Family

ID=7814475

Family Applications (1)

Application Number Title Priority Date Filing Date
ES97952027T Expired - Lifetime ES2182139T3 (es) 1996-12-12 1997-12-01 Dispersiones acuosas estables y polvos en seco, dispersables en agua estables de xantofilas, su obtencion y empleo.

Country Status (17)

Country Link
US (1) US6296877B1 (es)
EP (1) EP0944675B1 (es)
JP (1) JP4124821B2 (es)
CN (1) CN1101425C (es)
AT (1) ATE222278T1 (es)
AU (1) AU743203B2 (es)
CA (1) CA2274467C (es)
CO (1) CO5031308A1 (es)
DE (2) DE19651681A1 (es)
DK (1) DK0944675T3 (es)
ES (1) ES2182139T3 (es)
ID (1) ID21899A (es)
IS (1) IS5072A (es)
NO (1) NO312074B1 (es)
NZ (1) NZ336133A (es)
TW (1) TW493976B (es)
WO (1) WO1998026008A1 (es)

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DE19919751A1 (de) 1999-04-29 2000-11-09 Basf Ag Stabile, wäßrige Dispersionen und stabile, wasserdispergierbare Trockenpulver von Xanthophyllen, deren Herstellung und Verwendung
WO2001037781A2 (en) * 1999-10-28 2001-05-31 Ingredient Innovations International A stable aqueous dispersion of nutrients
US7105176B2 (en) 2000-11-29 2006-09-12 Basf Aktiengesellschaft Production of solid preparations of water-soluble, sparingly water-soluble or water-insoluble active compounds
DE10104494A1 (de) * 2001-01-31 2002-08-01 Basf Ag Verfahren zur Herstellung von Trockenpulvern eines oder mehrerer Carotinoide
DE20109224U1 (de) * 2001-06-01 2002-10-17 Marcus Gmbh & Co Kg Dr Farbstoff-Gemisch für Lebensmittel, Pharmazeutika und Kosmetika
AU2003242589A1 (en) * 2002-05-30 2003-12-19 Phares Pharmaceutical Research N.V. Oil-soluble pigment compositions
US6936279B2 (en) * 2002-06-18 2005-08-30 Zeavision Llc Microcrystalline zeaxanthin with high bioavailability in oily carrier formulations
GB0218932D0 (en) * 2002-08-14 2002-09-25 Zoolife Internat Ltd Composition for dietary enrichment
CA2529055C (en) 2003-06-19 2013-10-15 Advanced Bionutrition Corp. Improved absorption of fat-soluble nutrients
CN1833052B (zh) * 2003-08-08 2010-10-20 昭和电工株式会社 带有黑膜的基质的生产方法和带有黑膜的基质
US7541166B2 (en) * 2003-09-19 2009-06-02 Microfluidic Systems, Inc. Sonication to selectively lyse different cell types
DE102004006106A1 (de) * 2004-02-06 2005-08-25 Basf Ag Verfahren zur Herstellung von Trockenpulvern eines oder mehrerer Carotinolde
WO2005117849A1 (en) * 2004-05-28 2005-12-15 Unigen Pharmaceuticals, Inc. Diarylalkanes as potent inhibitors of binuclear enzymes
DE102004030072A1 (de) * 2004-06-23 2006-01-19 Basf Ag Wässrige Dispersionen schwer wasserlöslicher oder wasserunlöslicher Wirkstoffe und daraus hergestellte Trockenpulver
SG155959A1 (en) * 2004-09-28 2009-10-29 Chemaphor Inc Compositions and methods for promoting weight gain and feed conversion
DE102004057587A1 (de) * 2004-11-29 2006-06-08 Basf Ag Wässrige Dispersionen eines Gemisches schwer wasserlöslicher oder wasserunlöslicher Wirkstoffe und eines Einzellerproteinmaterials und daraus hergestellte Trockenpulver
GB0501365D0 (en) * 2005-01-21 2005-03-02 Promar As Compositions
EP2329815A1 (en) 2005-02-11 2011-06-08 Kalamazoo Holdings, Inc. A capsicum variety exhibiting a hyper-accumulation of zeaxanthin and products derived therefrom
US8592662B2 (en) 2005-02-11 2013-11-26 Kalamazoo Holdings, Inc. Capsicum variety exhibiting a hyper-accumulation of zeaxanthin and products derived therefrom
DE602006019084D1 (de) * 2005-05-23 2011-02-03 Phares Drug Delivery Ag Direkte lösung
DE102005031468A1 (de) * 2005-07-04 2007-01-18 Basf Ag Wässrige Suspensionen schwer wasserlöslicher oder wasserunlöslicher Wirkstoffe und daraus hergestellte Trockenpulver
CN101243032B (zh) * 2005-08-15 2012-10-10 法雷斯药品研究公司 虾青素的晶型
CN101177540B (zh) * 2006-11-10 2010-04-14 浙江医药股份有限公司新昌制药厂 叶黄素水溶性干粉的制备方法
EP1967081A1 (en) * 2007-03-05 2008-09-10 DSMIP Assets B.V. Process for the manufacture of a powder containing carotenoids
ES2311422B1 (es) * 2007-07-28 2009-10-13 Investigaciones Quimicas Y Farmaceuticas, S.A Formulacion de carotenoides dispersables en agua.
AU2008316225B2 (en) 2007-10-26 2014-06-19 Avivagen Inc. Compositions and methods for enhancing immune response
CN101461450B (zh) 2007-12-18 2011-12-28 浙江医药股份有限公司新昌制药厂 通过饮水补充动物体内类胡萝卜素的方法
WO2010112406A1 (de) * 2009-03-30 2010-10-07 Basf Se Gebrauchsfertige, stabile suspension teilamorpher carotinoidpartikel
CA2975313C (en) 2009-04-30 2020-06-30 Avivagen Inc. Methods and compositions for improving the health of animals
KR101876506B1 (ko) * 2015-11-24 2018-07-09 한국과학기술연구원 유청 단백질 기반의 푸코잔틴 미세분말 및 이의 제조방법
KR101876507B1 (ko) * 2015-11-24 2018-07-09 한국과학기술연구원 카세인 기반의 푸코잔틴 미세분말 및 이의 제조방법
CN108697149A (zh) * 2016-03-02 2018-10-23 巴斯夫欧洲公司 振动液滴形成
CN105876555A (zh) * 2016-05-27 2016-08-24 山东农业大学 一种紫薯花青素饮料
US10835456B2 (en) 2016-07-19 2020-11-17 Basf Se Propyl gallate-containing vitamin preparations
KR101875571B1 (ko) * 2016-11-04 2018-07-09 한국과학기술연구원 키토산으로 코팅된 카세인 기반의 푸코잔틴 미세분말 및 이의 제조방법
KR101876505B1 (ko) * 2016-11-04 2018-07-09 한국과학기술연구원 베타 사이클로덱스트린 기반의 푸코잔틴 미세분말 및 이의 제조방법
JP2021107340A (ja) * 2019-12-27 2021-07-29 小林製薬株式会社 経口組成物

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DE3702030A1 (de) 1987-01-24 1988-08-04 Basf Ag Pulverfoermige, wasserdispergierbare carotinoid-zubereitungen und verfahren zu ihrer herstellung
DE59003205D1 (de) 1989-07-25 1993-12-02 Hoffmann La Roche Verfahren zur Herstellung von Carotinoidpräparaten.
DK546289D0 (da) 1989-11-02 1989-11-02 Danochemo As Carotenoidpulvere
DK19393D0 (da) 1993-02-19 1993-02-19 Danochemo As Fremgangsmaade til fremstilling af et i vand dispergerbart pulverformigt carotenoidpraeparat

Also Published As

Publication number Publication date
CN1101425C (zh) 2003-02-12
IS5072A (is) 1999-06-08
EP0944675B1 (de) 2002-08-14
CA2274467C (en) 2006-08-01
ID21899A (id) 1999-08-12
US6296877B1 (en) 2001-10-02
DE19651681A1 (de) 1998-06-18
CO5031308A1 (es) 2001-04-27
CN1239977A (zh) 1999-12-29
NZ336133A (en) 2001-04-27
CA2274467A1 (en) 1998-06-18
AU5559698A (en) 1998-07-03
JP2001506685A (ja) 2001-05-22
NO992874D0 (no) 1999-06-11
EP0944675A1 (de) 1999-09-29
ATE222278T1 (de) 2002-08-15
WO1998026008A1 (de) 1998-06-18
DE59707985D1 (de) 2002-09-19
TW493976B (en) 2002-07-11
JP4124821B2 (ja) 2008-07-23
AU743203B2 (en) 2002-01-24
DK0944675T3 (da) 2002-10-07
NO312074B1 (no) 2002-03-11
NO992874L (no) 1999-06-11

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