ES2182133T3 - Composiciones farmaceuticas para liofilizar. - Google Patents
Composiciones farmaceuticas para liofilizar.Info
- Publication number
- ES2182133T3 ES2182133T3 ES97950542T ES97950542T ES2182133T3 ES 2182133 T3 ES2182133 T3 ES 2182133T3 ES 97950542 T ES97950542 T ES 97950542T ES 97950542 T ES97950542 T ES 97950542T ES 2182133 T3 ES2182133 T3 ES 2182133T3
- Authority
- ES
- Spain
- Prior art keywords
- liofilize
- pharmaceutical compositions
- polyol
- mannitol
- pharmaceutical composition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical group [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 abstract 2
- FBPFZTCFMRRESA-KVTDHHQDSA-N D-Mannitol Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-KVTDHHQDSA-N 0.000 abstract 1
- 229930195725 Mannitol Natural products 0.000 abstract 1
- 239000000654 additive Substances 0.000 abstract 1
- 230000000996 additive effect Effects 0.000 abstract 1
- 235000010355 mannitol Nutrition 0.000 abstract 1
- 239000000594 mannitol Substances 0.000 abstract 1
- 230000004048 modification Effects 0.000 abstract 1
- 238000012986 modification Methods 0.000 abstract 1
- -1 nucleotide analog compound Chemical class 0.000 abstract 1
- 229920005862 polyol Polymers 0.000 abstract 1
- 150000003077 polyols Chemical class 0.000 abstract 1
- 239000011780 sodium chloride Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
- A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
- A61K31/7076—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines containing purines, e.g. adenosine, adenylic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
- A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
- A61K31/704—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biochemistry (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Dermatology (AREA)
- Inorganic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Saccharide Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE9604795A SE9604795D0 (sv) | 1996-12-20 | 1996-12-20 | New pharmaceutical formulation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2182133T3 true ES2182133T3 (es) | 2003-03-01 |
Family
ID=20405148
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES97950542T Expired - Lifetime ES2182133T3 (es) | 1996-12-20 | 1997-12-11 | Composiciones farmaceuticas para liofilizar. |
Country Status (35)
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE9702680D0 (sv) * | 1997-07-11 | 1997-07-11 | Astra Pharma Prod | New formulation |
| US9427448B2 (en) | 2009-11-11 | 2016-08-30 | The Medicines Company | Methods of treating, reducing the incidence of, and/or preventing ischemic events |
| WO2009140092A1 (en) | 2008-05-13 | 2009-11-19 | The Medicines Company | Maintenance of platelet inhibition during antiplatelet therapy |
| US8759316B2 (en) | 2008-05-13 | 2014-06-24 | The Medicines Company | Maintenance of platelet inhibition during antiplatelet therapy |
| US20120141468A1 (en) * | 2008-05-13 | 2012-06-07 | Lisa Ruderman Chen | Maintenance of platelet inhibition during antiplatelet therapy |
| US20130303477A1 (en) | 2008-05-13 | 2013-11-14 | The Medicines Company | Maintenance of Platelet Inhibition During Antiplatelet Therapy |
| US10376532B2 (en) | 2009-11-11 | 2019-08-13 | Chiesi Farmaceutici, S.P.A. | Methods of treating, reducing the incidence of, and/or preventing ischemic events |
| CA2778880C (en) | 2009-11-11 | 2018-02-13 | The Medicines Company | Methods of treating or preventing stent thrombosis |
| JP5947316B2 (ja) | 2011-02-09 | 2016-07-06 | ザ メディシンズ カンパニー | 肺高血圧症を処置するための方法 |
| CN115120606A (zh) | 2013-03-09 | 2022-09-30 | 奇斯药制品公司 | 治疗局部缺血事件、减少局部缺血事件的发生和/或预防局部缺血事件的方法 |
| CN103772461A (zh) * | 2014-01-06 | 2014-05-07 | 南京正科制药有限公司 | 一种坎格雷洛晶型ⅰ |
| MA41326A (fr) * | 2015-01-14 | 2021-04-28 | Chiesi Farm Spa | Formulations pharmaceutiques comprenant du cangrelor de haute pureté et leurs procédés de préparation et d'utilisation |
| MX2019015448A (es) | 2017-06-23 | 2020-02-19 | Chiesi Farm Spa | Metodo para la prevencion de trombosis de desviacion de la arteria sistemica a pulmonar. |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5637967B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) * | 1973-05-17 | 1981-09-03 | ||
| JPH01228915A (ja) * | 1988-03-09 | 1989-09-12 | Dai Ichi Seiyaku Co Ltd | Ａｔｐ凍結乾燥製剤 |
| GB8903593D0 (en) * | 1989-02-16 | 1989-04-05 | Pafra Ltd | Storage of materials |
| CZ281415B6 (cs) * | 1989-11-09 | 1996-09-11 | Masarykova Nemocnice S Poliklinikou Iii. Typu | Způsob přípravy přenosového faktoru z buffy coatu savčí krve |
| GB9010742D0 (en) * | 1990-05-14 | 1990-07-04 | Quadrant Bioresources Ltd | Stabilization of biological macromolecular substances |
| AU659645B2 (en) * | 1991-06-26 | 1995-05-25 | Inhale Therapeutic Systems | Storage of materials |
| KR0131678B1 (ko) * | 1991-12-09 | 1998-04-17 | 유미꾸라 레이이찌 | 파라티로이드 호르몬류의 안정화 조성물 |
| CA2155673C (en) * | 1993-02-10 | 2004-08-17 | Anthony Howard Ingall | N-alkyl-2-substituted atp analogues |
-
1996
- 1996-12-20 SE SE9604795A patent/SE9604795D0/xx unknown
- 1996-12-20 ID IDW990482A patent/ID21635A/id unknown
-
1997
- 1997-12-08 TW TW086118448A patent/TW522015B/zh active
- 1997-12-09 ZA ZA9711055A patent/ZA9711055B/xx unknown
- 1997-12-11 ES ES97950542T patent/ES2182133T3/es not_active Expired - Lifetime
- 1997-12-11 CZ CZ0220199A patent/CZ300635B6/cs not_active IP Right Cessation
- 1997-12-11 JP JP52867398A patent/JP4488538B2/ja not_active Expired - Lifetime
- 1997-12-11 TR TR1999/01412T patent/TR199901412T2/xx unknown
- 1997-12-11 IL IL13044997A patent/IL130449A0/xx not_active IP Right Cessation
- 1997-12-11 EE EEP199900260A patent/EE03857B1/xx unknown
- 1997-12-11 US US09/043,159 patent/US6114313A/en not_active Expired - Lifetime
- 1997-12-11 PL PL97334006A patent/PL190493B1/pl unknown
- 1997-12-11 CA CA002275153A patent/CA2275153C/en not_active Expired - Lifetime
- 1997-12-11 SI SI9730403T patent/SI1007094T1/xx unknown
- 1997-12-11 RU RU99115747/14A patent/RU2205012C2/ru active
- 1997-12-11 SK SK764-99A patent/SK283137B6/sk not_active IP Right Cessation
- 1997-12-11 EP EP97950542A patent/EP1007094B1/en not_active Expired - Lifetime
- 1997-12-11 NZ NZ336027A patent/NZ336027A/en not_active IP Right Cessation
- 1997-12-11 BR BRPI9713974-2A patent/BR9713974B1/pt not_active IP Right Cessation
- 1997-12-11 AU AU53515/98A patent/AU758857B2/en not_active Expired
- 1997-12-11 KR KR1019997005584A patent/KR100552880B1/ko not_active Expired - Lifetime
- 1997-12-11 DE DE69714616T patent/DE69714616T2/de not_active Expired - Lifetime
- 1997-12-11 HU HU0000572A patent/HU226616B1/hu unknown
- 1997-12-11 AT AT97950542T patent/ATE221787T1/de active
- 1997-12-11 UA UA99074153A patent/UA66779C2/uk unknown
- 1997-12-11 DK DK97950542T patent/DK1007094T3/da active
- 1997-12-11 WO PCT/SE1997/002068 patent/WO1998028009A1/en active IP Right Grant
- 1997-12-11 CN CN97180744A patent/CN1121875C/zh not_active Expired - Lifetime
- 1997-12-11 PT PT97950542T patent/PT1007094E/pt unknown
- 1997-12-17 SA SA97180719A patent/SA97180719B1/ar unknown
- 1997-12-19 MY MYPI97006175A patent/MY121982A/en unknown
- 1997-12-19 AR ARP970106075A patent/AR010377A1/es active IP Right Grant
-
1999
- 1999-06-03 IS IS5064A patent/IS1897B/is unknown
- 1999-06-21 NO NO19993067A patent/NO327142B1/no not_active IP Right Cessation
-
2015
- 2015-09-07 FR FR15C0060C patent/FR15C0060I2/fr active Active
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