ES2178478T3 - Composiciones farmaceuticas a base de alfa-ciclodextrina destinada a la administracion oral de analogos de lh-rh. - Google Patents

Composiciones farmaceuticas a base de alfa-ciclodextrina destinada a la administracion oral de analogos de lh-rh.

Info

Publication number
ES2178478T3
ES2178478T3 ES99948935T ES99948935T ES2178478T3 ES 2178478 T3 ES2178478 T3 ES 2178478T3 ES 99948935 T ES99948935 T ES 99948935T ES 99948935 T ES99948935 T ES 99948935T ES 2178478 T3 ES2178478 T3 ES 2178478T3
Authority
ES
Spain
Prior art keywords
oral administration
cyclodextrine
alfa
analogs
intended
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES99948935T
Other languages
English (en)
Inventor
Remi Delansorne
Paule Bonnet
Jacques Paris
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Laboratoire Theramex SAM
Original Assignee
Laboratoire Theramex SAM
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laboratoire Theramex SAM filed Critical Laboratoire Theramex SAM
Application granted granted Critical
Publication of ES2178478T3 publication Critical patent/ES2178478T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/24—Follicle-stimulating hormone [FSH]; Chorionic gonadotropins, e.g. HCG; Luteinising hormone [LH]; Thyroid-stimulating hormone [TSH]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08—Peptides having 5 to 11 amino acids
    • A61K38/09—Luteinising hormone-releasing hormone [LHRH], i.e. Gonadotropin-releasing hormone [GnRH]; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/40—Cyclodextrins; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/16—Masculine contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/18—Feminine contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/02—Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin
    • A61P5/04—Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin for decreasing, blocking or antagonising the activity of the hypothalamic hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Endocrinology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Reproductive Health (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Diabetes (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Zoology (AREA)
  • Inorganic Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Peptides Or Proteins (AREA)

Abstract

El uso de una a-ciclodextrina o uno de sus derivados para la preparación de preparado farmacéutico para la administración oral de un análogo peptídico de LH-RH o una de sus sales farmacéuticamente aceptables.
ES99948935T 1998-09-30 1999-09-23 Composiciones farmaceuticas a base de alfa-ciclodextrina destinada a la administracion oral de analogos de lh-rh. Expired - Lifetime ES2178478T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP98402403A EP0998940A1 (en) 1998-09-30 1998-09-30 Pharmaceutical compositions based on alpha-cyclodextrin for the oral administration of LH-RH analogues

Publications (1)

Publication Number Publication Date
ES2178478T3 true ES2178478T3 (es) 2002-12-16

Family

ID=8235503

Family Applications (1)

Application Number Title Priority Date Filing Date
ES99948935T Expired - Lifetime ES2178478T3 (es) 1998-09-30 1999-09-23 Composiciones farmaceuticas a base de alfa-ciclodextrina destinada a la administracion oral de analogos de lh-rh.

Country Status (28)

Country Link
EP (2) EP0998940A1 (es)
JP (1) JP4485060B2 (es)
KR (1) KR100652457B1 (es)
CN (1) CN1200727C (es)
AR (1) AR023056A1 (es)
AT (1) ATE218358T1 (es)
AU (1) AU756233B2 (es)
BR (1) BR9914125A (es)
CA (1) CA2344470C (es)
CZ (1) CZ302343B6 (es)
DE (1) DE69901721T2 (es)
DK (1) DK1117420T3 (es)
EE (1) EE04872B1 (es)
ES (1) ES2178478T3 (es)
HK (1) HK1042047B (es)
HU (1) HUP0103649A3 (es)
ID (1) ID28650A (es)
IL (2) IL142112A0 (es)
MX (1) MXPA01003340A (es)
NO (1) NO330234B1 (es)
NZ (1) NZ510446A (es)
PL (1) PL200693B1 (es)
PT (1) PT1117420E (es)
RU (1) RU2214270C2 (es)
SI (1) SI1117420T1 (es)
TR (1) TR200100887T2 (es)
WO (1) WO2000018423A1 (es)
ZA (1) ZA200102452B (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10024451A1 (de) * 2000-05-18 2001-11-29 Asta Medica Ag Pharmazeutische Darreichungsform für Peptide, Verfahren zu deren Herstellung und Verwendung
SE0104462D0 (sv) 2001-12-29 2001-12-29 Carlbiotech Ltd As Peptide purifcation (Peptidrening)

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4659696A (en) * 1982-04-30 1987-04-21 Takeda Chemical Industries, Ltd. Pharmaceutical composition and its nasal or vaginal use
US4659969A (en) * 1984-08-09 1987-04-21 Synektron Corporation Variable reluctance actuator having position sensing and control
PT88490B (pt) * 1987-09-14 1992-11-30 Novo Nordisk As Processo para a preparacao de composicoes farmaceuticas para libertacao nao-enterica trans-mucosa contendo monossacaridos ou oligossacaridos
SI9300470A (en) * 1993-09-10 1995-04-30 Lek Tovarna Farmacevtskih Inclusion complexes of optically active and racemic ibuproxan with cyclodextrin derivates,process for their preparation,pharmaceutical preparations comprising the same and their use
JPH11292787A (ja) * 1995-08-15 1999-10-26 Asahi Chem Ind Co Ltd 生理活性ペプチドを含有する経粘膜投与製剤
EP0839525B1 (en) * 1996-10-31 2004-08-04 Takeda Chemical Industries, Ltd. Sustained-release preparation
EP0842946A1 (en) * 1996-11-14 1998-05-20 Laboratoire Theramex S.A. Conformationally constrained LH-RH analogues, their uses and pharmaceutical compositions containing them

Also Published As

Publication number Publication date
RU2214270C2 (ru) 2003-10-20
IL142112A (en) 2006-10-31
ATE218358T1 (de) 2002-06-15
NO20011576L (no) 2001-03-28
AU756233B2 (en) 2003-01-09
CA2344470C (en) 2009-01-06
SI1117420T1 (en) 2002-12-31
WO2000018423A1 (en) 2000-04-06
NO330234B1 (no) 2011-03-07
PL200693B1 (pl) 2009-01-30
AR023056A1 (es) 2002-09-04
NZ510446A (en) 2003-01-31
EP1117420A1 (en) 2001-07-25
ID28650A (id) 2001-06-21
ZA200102452B (en) 2002-03-26
PT1117420E (pt) 2002-10-31
PL346939A1 (en) 2002-03-11
HUP0103649A3 (en) 2002-05-28
CN1324241A (zh) 2001-11-28
DE69901721D1 (de) 2002-07-11
CA2344470A1 (en) 2000-04-06
HK1042047B (zh) 2005-12-16
EE04872B1 (et) 2007-08-15
CZ302343B6 (cs) 2011-03-23
DK1117420T3 (da) 2002-09-16
CN1200727C (zh) 2005-05-11
KR20010075255A (ko) 2001-08-09
CZ20011173A3 (cs) 2001-09-12
DE69901721T2 (de) 2003-01-09
JP2002525336A (ja) 2002-08-13
JP4485060B2 (ja) 2010-06-16
KR100652457B1 (ko) 2006-11-30
EP0998940A1 (en) 2000-05-10
EE200100196A (et) 2002-06-17
IL142112A0 (en) 2002-03-10
BR9914125A (pt) 2001-06-19
NO20011576D0 (no) 2001-03-28
AU6199999A (en) 2000-04-17
HUP0103649A2 (hu) 2002-02-28
MXPA01003340A (es) 2004-04-21
EP1117420B1 (en) 2002-06-05
TR200100887T2 (tr) 2001-10-22

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