ATE218358T1 - Pharmazeutische zusammensetzungen basierend auf alpha-cyclodextrin zur oralen verabreichung von lh-rh analogen - Google Patents

Pharmazeutische zusammensetzungen basierend auf alpha-cyclodextrin zur oralen verabreichung von lh-rh analogen

Info

Publication number
ATE218358T1
ATE218358T1 AT99948935T AT99948935T ATE218358T1 AT E218358 T1 ATE218358 T1 AT E218358T1 AT 99948935 T AT99948935 T AT 99948935T AT 99948935 T AT99948935 T AT 99948935T AT E218358 T1 ATE218358 T1 AT E218358T1
Authority
AT
Austria
Prior art keywords
cyclodextrin
analogues
alpha
pharmaceutical compositions
oral administration
Prior art date
Application number
AT99948935T
Other languages
English (en)
Inventor
Remi Delansorne
Paule Bonnet
Jacques Paris
Original Assignee
Theramex
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Theramex filed Critical Theramex
Application granted granted Critical
Publication of ATE218358T1 publication Critical patent/ATE218358T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/24—Follicle-stimulating hormone [FSH]; Chorionic gonadotropins, e.g. HCG; Luteinising hormone [LH]; Thyroid-stimulating hormone [TSH]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08—Peptides having 5 to 11 amino acids
    • A61K38/09—Luteinising hormone-releasing hormone [LHRH], i.e. Gonadotropin-releasing hormone [GnRH]; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/40—Cyclodextrins; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/16—Masculine contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/18—Feminine contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/02—Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin
    • A61P5/04—Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin for decreasing, blocking or antagonising the activity of the hypothalamic hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Endocrinology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Reproductive Health (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Diabetes (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Zoology (AREA)
  • Inorganic Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Peptides Or Proteins (AREA)
AT99948935T 1998-09-30 1999-09-23 Pharmazeutische zusammensetzungen basierend auf alpha-cyclodextrin zur oralen verabreichung von lh-rh analogen ATE218358T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP98402403A EP0998940A1 (de) 1998-09-30 1998-09-30 Pharmazeutische zusammensetzung basierend auf alpha-cyclodextrin für die orale verabreichung von LH-RH analogen
PCT/EP1999/007389 WO2000018423A1 (en) 1998-09-30 1999-09-23 Pharmaceutical compositions based on alpha-cyclodextrin for the oral administration of lh-rh analogues

Publications (1)

Publication Number Publication Date
ATE218358T1 true ATE218358T1 (de) 2002-06-15

Family

ID=8235503

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99948935T ATE218358T1 (de) 1998-09-30 1999-09-23 Pharmazeutische zusammensetzungen basierend auf alpha-cyclodextrin zur oralen verabreichung von lh-rh analogen

Country Status (28)

Country Link
EP (2) EP0998940A1 (de)
JP (1) JP4485060B2 (de)
KR (1) KR100652457B1 (de)
CN (1) CN1200727C (de)
AR (1) AR023056A1 (de)
AT (1) ATE218358T1 (de)
AU (1) AU756233B2 (de)
BR (1) BR9914125A (de)
CA (1) CA2344470C (de)
CZ (1) CZ302343B6 (de)
DE (1) DE69901721T2 (de)
DK (1) DK1117420T3 (de)
EE (1) EE04872B1 (de)
ES (1) ES2178478T3 (de)
HK (1) HK1042047B (de)
HU (1) HUP0103649A3 (de)
ID (1) ID28650A (de)
IL (2) IL142112A0 (de)
MX (1) MXPA01003340A (de)
NO (1) NO330234B1 (de)
NZ (1) NZ510446A (de)
PL (1) PL200693B1 (de)
PT (1) PT1117420E (de)
RU (1) RU2214270C2 (de)
SI (1) SI1117420T1 (de)
TR (1) TR200100887T2 (de)
WO (1) WO2000018423A1 (de)
ZA (1) ZA200102452B (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10024451A1 (de) * 2000-05-18 2001-11-29 Asta Medica Ag Pharmazeutische Darreichungsform für Peptide, Verfahren zu deren Herstellung und Verwendung
SE0104462D0 (sv) 2001-12-29 2001-12-29 Carlbiotech Ltd As Peptide purifcation (Peptidrening)

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4659696A (en) * 1982-04-30 1987-04-21 Takeda Chemical Industries, Ltd. Pharmaceutical composition and its nasal or vaginal use
US4659969A (en) * 1984-08-09 1987-04-21 Synektron Corporation Variable reluctance actuator having position sensing and control
PT88490B (pt) * 1987-09-14 1992-11-30 Novo Nordisk As Processo para a preparacao de composicoes farmaceuticas para libertacao nao-enterica trans-mucosa contendo monossacaridos ou oligossacaridos
SI9300470A (en) * 1993-09-10 1995-04-30 Lek Tovarna Farmacevtskih Inclusion complexes of optically active and racemic ibuproxan with cyclodextrin derivates,process for their preparation,pharmaceutical preparations comprising the same and their use
JPH11292787A (ja) * 1995-08-15 1999-10-26 Asahi Chem Ind Co Ltd 生理活性ペプチドを含有する経粘膜投与製剤
EP0839525B1 (de) * 1996-10-31 2004-08-04 Takeda Chemical Industries, Ltd. Zubereitung mit verzögerter Freisetzung
EP0842946A1 (de) * 1996-11-14 1998-05-20 Laboratoire Theramex S.A. LHRH Analoge mit starrer Konformation, deren Verwendungen und pharmazeutische Zusammensetzungen

Also Published As

Publication number Publication date
RU2214270C2 (ru) 2003-10-20
IL142112A (en) 2006-10-31
NO20011576L (no) 2001-03-28
AU756233B2 (en) 2003-01-09
ES2178478T3 (es) 2002-12-16
CA2344470C (en) 2009-01-06
SI1117420T1 (en) 2002-12-31
WO2000018423A1 (en) 2000-04-06
NO330234B1 (no) 2011-03-07
PL200693B1 (pl) 2009-01-30
AR023056A1 (es) 2002-09-04
NZ510446A (en) 2003-01-31
EP1117420A1 (de) 2001-07-25
ID28650A (id) 2001-06-21
ZA200102452B (en) 2002-03-26
PT1117420E (pt) 2002-10-31
PL346939A1 (en) 2002-03-11
HUP0103649A3 (en) 2002-05-28
CN1324241A (zh) 2001-11-28
DE69901721D1 (de) 2002-07-11
CA2344470A1 (en) 2000-04-06
HK1042047B (zh) 2005-12-16
EE04872B1 (et) 2007-08-15
CZ302343B6 (cs) 2011-03-23
DK1117420T3 (da) 2002-09-16
CN1200727C (zh) 2005-05-11
KR20010075255A (ko) 2001-08-09
CZ20011173A3 (cs) 2001-09-12
DE69901721T2 (de) 2003-01-09
JP2002525336A (ja) 2002-08-13
JP4485060B2 (ja) 2010-06-16
KR100652457B1 (ko) 2006-11-30
EP0998940A1 (de) 2000-05-10
EE200100196A (et) 2002-06-17
IL142112A0 (en) 2002-03-10
BR9914125A (pt) 2001-06-19
NO20011576D0 (no) 2001-03-28
AU6199999A (en) 2000-04-17
HUP0103649A2 (hu) 2002-02-28
MXPA01003340A (es) 2004-04-21
EP1117420B1 (de) 2002-06-05
TR200100887T2 (tr) 2001-10-22

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