EE04872B1 - a-tsklodekstriini v?i selle derivaadi kasutamineLH-RH peptiidanaloogi sisaldavate farmatseutiliste kompositsioonide valmistamiseks ja a-tsklodekstriinil p?hinev farmatseutiline kompositsioon LH-RHpeptiidanaloogide peroraalseks manustamiseks - Google Patents

a-tsklodekstriini v?i selle derivaadi kasutamineLH-RH peptiidanaloogi sisaldavate farmatseutiliste kompositsioonide valmistamiseks ja a-tsklodekstriinil p?hinev farmatseutiline kompositsioon LH-RHpeptiidanaloogide peroraalseks manustamiseks

Info

Publication number
EE04872B1
EE04872B1 EEP200100196A EEP200100196A EE04872B1 EE 04872 B1 EE04872 B1 EE 04872B1 EE P200100196 A EEP200100196 A EE P200100196A EE P200100196 A EEP200100196 A EE P200100196A EE 04872 B1 EE04872 B1 EE 04872B1
Authority
EE
Estonia
Prior art keywords
clodextrin
peptide
derivative
preparation
oral administration
Prior art date
Application number
EEP200100196A
Other languages
English (en)
Inventor
Delansorne R�mi
Bonnet Paule
Paris Jacques
Original Assignee
Laboratoire Theramex
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laboratoire Theramex filed Critical Laboratoire Theramex
Publication of EE200100196A publication Critical patent/EE200100196A/et
Publication of EE04872B1 publication Critical patent/EE04872B1/et

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22Hormones
    • A61K38/24Follicle-stimulating hormone [FSH]; Chorionic gonadotropins, e.g. HCG; Luteinising hormone [LH]; Thyroid-stimulating hormone [TSH]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08Peptides having 5 to 11 amino acids
    • A61K38/09Luteinising hormone-releasing hormone [LHRH], i.e. Gonadotropin-releasing hormone [GnRH]; Related peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/40Cyclodextrins; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/16Masculine contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/18Feminine contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/02Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin
    • A61P5/04Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin for decreasing, blocking or antagonising the activity of the hypothalamic hormones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/06Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/24Drugs for disorders of the endocrine system of the sex hormones

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Endocrinology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Reproductive Health (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Diabetes (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Zoology (AREA)
  • Inorganic Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Peptides Or Proteins (AREA)
EEP200100196A 1998-09-30 1999-09-23 a-tsklodekstriini v?i selle derivaadi kasutamineLH-RH peptiidanaloogi sisaldavate farmatseutiliste kompositsioonide valmistamiseks ja a-tsklodekstriinil p?hinev farmatseutiline kompositsioon LH-RHpeptiidanaloogide peroraalseks manustamiseks EE04872B1 (et)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP98402403A EP0998940A1 (en) 1998-09-30 1998-09-30 Pharmaceutical compositions based on alpha-cyclodextrin for the oral administration of LH-RH analogues
PCT/EP1999/007389 WO2000018423A1 (en) 1998-09-30 1999-09-23 Pharmaceutical compositions based on alpha-cyclodextrin for the oral administration of lh-rh analogues

Publications (2)

Publication Number Publication Date
EE200100196A EE200100196A (et) 2002-06-17
EE04872B1 true EE04872B1 (et) 2007-08-15

Family

ID=8235503

Family Applications (1)

Application Number Title Priority Date Filing Date
EEP200100196A EE04872B1 (et) 1998-09-30 1999-09-23 a-tsklodekstriini v?i selle derivaadi kasutamineLH-RH peptiidanaloogi sisaldavate farmatseutiliste kompositsioonide valmistamiseks ja a-tsklodekstriinil p?hinev farmatseutiline kompositsioon LH-RHpeptiidanaloogide peroraalseks manustamiseks

Country Status (28)

Country Link
EP (2) EP0998940A1 (et)
JP (1) JP4485060B2 (et)
KR (1) KR100652457B1 (et)
CN (1) CN1200727C (et)
AR (1) AR023056A1 (et)
AT (1) ATE218358T1 (et)
AU (1) AU756233B2 (et)
BR (1) BR9914125A (et)
CA (1) CA2344470C (et)
CZ (1) CZ302343B6 (et)
DE (1) DE69901721T2 (et)
DK (1) DK1117420T3 (et)
EE (1) EE04872B1 (et)
ES (1) ES2178478T3 (et)
HK (1) HK1042047B (et)
HU (1) HUP0103649A3 (et)
ID (1) ID28650A (et)
IL (2) IL142112A0 (et)
MX (1) MXPA01003340A (et)
NO (1) NO330234B1 (et)
NZ (1) NZ510446A (et)
PL (1) PL200693B1 (et)
PT (1) PT1117420E (et)
RU (1) RU2214270C2 (et)
SI (1) SI1117420T1 (et)
TR (1) TR200100887T2 (et)
WO (1) WO2000018423A1 (et)
ZA (1) ZA200102452B (et)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10024451A1 (de) * 2000-05-18 2001-11-29 Asta Medica Ag Pharmazeutische Darreichungsform für Peptide, Verfahren zu deren Herstellung und Verwendung
SE0104462D0 (sv) 2001-12-29 2001-12-29 Carlbiotech Ltd As Peptide purifcation (Peptidrening)

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4659696A (en) * 1982-04-30 1987-04-21 Takeda Chemical Industries, Ltd. Pharmaceutical composition and its nasal or vaginal use
US4659969A (en) * 1984-08-09 1987-04-21 Synektron Corporation Variable reluctance actuator having position sensing and control
PT88490B (pt) * 1987-09-14 1992-11-30 Novo Nordisk As Processo para a preparacao de composicoes farmaceuticas para libertacao nao-enterica trans-mucosa contendo monossacaridos ou oligossacaridos
SI9300470A (en) * 1993-09-10 1995-04-30 Lek Tovarna Farmacevtskih Inclusion complexes of optically active and racemic ibuproxan with cyclodextrin derivates,process for their preparation,pharmaceutical preparations comprising the same and their use
JPH11292787A (ja) * 1995-08-15 1999-10-26 Asahi Chem Ind Co Ltd 生理活性ペプチドを含有する経粘膜投与製剤
EP0839525B1 (en) * 1996-10-31 2004-08-04 Takeda Chemical Industries, Ltd. Sustained-release preparation
EP0842946A1 (en) * 1996-11-14 1998-05-20 Laboratoire Theramex S.A. Conformationally constrained LH-RH analogues, their uses and pharmaceutical compositions containing them

Also Published As

Publication number Publication date
RU2214270C2 (ru) 2003-10-20
IL142112A (en) 2006-10-31
ATE218358T1 (de) 2002-06-15
NO20011576L (no) 2001-03-28
AU756233B2 (en) 2003-01-09
ES2178478T3 (es) 2002-12-16
CA2344470C (en) 2009-01-06
SI1117420T1 (en) 2002-12-31
WO2000018423A1 (en) 2000-04-06
NO330234B1 (no) 2011-03-07
PL200693B1 (pl) 2009-01-30
AR023056A1 (es) 2002-09-04
NZ510446A (en) 2003-01-31
EP1117420A1 (en) 2001-07-25
ID28650A (id) 2001-06-21
ZA200102452B (en) 2002-03-26
PT1117420E (pt) 2002-10-31
PL346939A1 (en) 2002-03-11
HUP0103649A3 (en) 2002-05-28
CN1324241A (zh) 2001-11-28
DE69901721D1 (de) 2002-07-11
CA2344470A1 (en) 2000-04-06
HK1042047B (zh) 2005-12-16
CZ302343B6 (cs) 2011-03-23
DK1117420T3 (da) 2002-09-16
CN1200727C (zh) 2005-05-11
KR20010075255A (ko) 2001-08-09
CZ20011173A3 (cs) 2001-09-12
DE69901721T2 (de) 2003-01-09
JP2002525336A (ja) 2002-08-13
JP4485060B2 (ja) 2010-06-16
KR100652457B1 (ko) 2006-11-30
EP0998940A1 (en) 2000-05-10
EE200100196A (et) 2002-06-17
IL142112A0 (en) 2002-03-10
BR9914125A (pt) 2001-06-19
NO20011576D0 (no) 2001-03-28
AU6199999A (en) 2000-04-17
HUP0103649A2 (hu) 2002-02-28
MXPA01003340A (es) 2004-04-21
EP1117420B1 (en) 2002-06-05
TR200100887T2 (tr) 2001-10-22

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Legal Events

Date Code Title Description
KB4A Valid patent at the end of a year

Effective date: 20071231

KB4A Valid patent at the end of a year

Effective date: 20081231

KB4A Valid patent at the end of a year

Effective date: 20101231

MM4A Lapsed by not paying the annual fees

Effective date: 20110923