ES2175167T3 - Procedimiento para la preparacion de cefdinir. - Google Patents

Procedimiento para la preparacion de cefdinir.

Info

Publication number
ES2175167T3
ES2175167T3 ES96943357T ES96943357T ES2175167T3 ES 2175167 T3 ES2175167 T3 ES 2175167T3 ES 96943357 T ES96943357 T ES 96943357T ES 96943357 T ES96943357 T ES 96943357T ES 2175167 T3 ES2175167 T3 ES 2175167T3
Authority
ES
Spain
Prior art keywords
cefdinir
pct
date
preparation
sec
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES96943357T
Other languages
English (en)
Inventor
Gwan Sun Lee
Young Kil Chang
Jong Pil Chun
Joon Hyung Koh
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hanmi Pharmaceutical Co Ltd
Original Assignee
Hanmi Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from KR1019950058694A external-priority patent/KR0174432B1/ko
Priority claimed from KR1019950058695A external-priority patent/KR0174431B1/ko
Application filed by Hanmi Pharmaceutical Co Ltd filed Critical Hanmi Pharmaceutical Co Ltd
Application granted granted Critical
Publication of ES2175167T3 publication Critical patent/ES2175167T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Abstract

LA PRESENTE INVENCION TRATA DE UN NUEVO COMPUESTO INTERMEDIO CRISTALINO DE CEFDINIR CON FORMULA (II) QUE SE PUEDE UTILIZAR MUY BIEN PARA PREPARAR UN ANTIBIOTICO DE CEFALOSPORINA, CEFDINIR, EN LA CUAL PH SIGNIFICA FENILO, P - TSOH REPRESENTA ACIDO P TOLUENSULFONICO Y DMAC REPRESENTA N,N - DIMETILACETAMIDA, TAMBIEN TRATA DE UN PROCEDIMIENTO PARA SU PREPARACION Y DE UN PROCEDIMIENTO PARA PREPARAR CEFDINIR UTILIZANDO EL COMPUESTO DE FORMULA (II). SEGUN LA PRESENTE INVENCION, CEFDINIR SE PUEDE PREPARAR CON UN BUEN RENDIMIENTO Y CON EXCELENTE COLOR Y PUREZA.
ES96943357T 1995-12-27 1996-12-26 Procedimiento para la preparacion de cefdinir. Expired - Lifetime ES2175167T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR1019950058694A KR0174432B1 (ko) 1995-12-27 1995-12-27 신규한 결정성 세프디니르 중간체 및 그의 제조방법
KR1019950058695A KR0174431B1 (ko) 1995-12-27 1995-12-27 세프디니르의 제조방법

Publications (1)

Publication Number Publication Date
ES2175167T3 true ES2175167T3 (es) 2002-11-16

Family

ID=26631527

Family Applications (1)

Application Number Title Priority Date Filing Date
ES96943357T Expired - Lifetime ES2175167T3 (es) 1995-12-27 1996-12-26 Procedimiento para la preparacion de cefdinir.

Country Status (9)

Country Link
US (1) US6093814A (es)
EP (1) EP0874853B1 (es)
JP (1) JP3948628B2 (es)
AT (1) ATE218572T1 (es)
DE (1) DE69621649T2 (es)
DK (1) DK0874853T3 (es)
ES (1) ES2175167T3 (es)
PT (1) PT874853E (es)
WO (1) WO1997024358A1 (es)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5883247A (en) * 1996-06-10 1999-03-16 Hoffmann-La Roche Inc. Preparation of cephem and isooxacephem derivatives
AT405283B (de) 1997-04-04 1999-06-25 Biochemie Gmbh Neues kristallines 7-(z)-(2-(2-aminothiazol-4-yl) -2-hydroxyiminoacetamido)-3-vinyl-3-cephem-4- carbonsäure dicyclohexylammoniumsalz und verfahren zu dessen herstellung
US20080113025A1 (en) * 1998-11-02 2008-05-15 Elan Pharma International Limited Compositions comprising nanoparticulate naproxen and controlled release hydrocodone
JP4544692B2 (ja) * 2000-04-13 2010-09-15 大塚化学株式会社 ３−ビニル−セフェム化合物の製造方法
KR100451672B1 (ko) * 2001-06-05 2004-10-08 한미약품 주식회사 결정성 세프디니르 산부가염, 이의 제조방법 및 이를이용한 세프디니르의 제조방법
ITMI20012364A1 (it) * 2001-11-09 2003-05-09 Antibioticos Spa Processo di sintesi della cefixima via alchil-o arilsolfonati
JP2005516011A (ja) * 2001-12-13 2005-06-02 ランバクシー ラボラトリーズ リミテッド 結晶二水化セフニディールカリウム
EA200401428A1 (ru) * 2002-04-26 2006-04-28 Рэнбакси Лабораториз Лимитед Способ получения цефдинира
ITMI20020913A0 (it) * 2002-04-29 2002-04-29 Acs Dobfar Spa Nuova forma cristallina del cefdinir
KR20050087776A (ko) * 2002-08-13 2005-08-31 산도즈 아게 세프디니르 중간체
ITMI20022076A1 (it) * 2002-10-01 2004-04-02 Antibioticos Spa Sali di intermedi del cefdinir.
EP1609793A4 (en) * 2003-03-24 2008-06-25 Sandoz Ag NOVEL 7- 2- (2-AMINOTHIAZOLE-4-YL) -2-HYDROXYIMIN OACETAMIDO-3-VINYL-3-CEPHEM-4-CARBOXYLIC ACID CRYSTAL (SYNTHETIC ISOMER) AND PROCESS FOR PREPARING THE SAME
WO2004104010A1 (en) * 2003-05-20 2004-12-02 Ranbaxy Laboratories Limited Crystalline form of cefdinir
US20050137182A1 (en) * 2003-06-02 2005-06-23 Ramesh Dandala Novel crystalline form of cefdinir
US20040242556A1 (en) * 2003-06-02 2004-12-02 Ramesh Dandala Novel crystalline form of cefdinir
US20050113355A1 (en) * 2003-09-12 2005-05-26 Duerst Richard W. Cefdinir pyridine salt
US20050059818A1 (en) * 2003-09-12 2005-03-17 Duerst Richard W. Polymorph of a pharmaceutical
US20050059819A1 (en) * 2003-09-12 2005-03-17 Duerst Richard W. Cefdinir pyridine salt
US20060211676A1 (en) * 2004-03-16 2006-09-21 Devalina Law Crystalline anhydrous cefdinir and crystalline cefdinir hydrates
US20060142563A1 (en) * 2004-03-16 2006-06-29 Devalina Law Crystalline anhydrous cefdinir and crystalline cefdinir hydrates
US20060142261A1 (en) * 2004-03-16 2006-06-29 Devalina Law Crystalline anhydrous cefdinir and crystalline cefdinir hydrates
US20050209211A1 (en) * 2004-03-16 2005-09-22 Devalina Law Trihemihydrate, anhydrate and novel hydrate forms of Cefdinir
US20060069079A1 (en) * 2004-09-27 2006-03-30 Sever Nancy E Stable amorphous cefdinir
US20050245738A1 (en) * 2004-05-03 2005-11-03 Lupin Ltd Stable bioavailable crystalline form or cefdinir and a process for the preparation thereof
WO2006010978A1 (en) * 2004-06-30 2006-02-02 Wockhardt Limited Cefdinir polymorphic forms, and imidazole salt
WO2006018807A1 (en) * 2004-08-16 2006-02-23 Ranbaxy Laboratories Limited Crystalline forms of cefdinir
MX2007006018A (es) * 2004-11-30 2007-06-07 Astellas Pharma Inc Suspension farmaceutica oral novedosa de cristal de cefdinir.
KR20080064990A (ko) * 2005-10-31 2008-07-10 테바 파마슈티컬 인더스트리즈 리미티드 세프디니르의 제조방법
US20070128268A1 (en) * 2005-12-07 2007-06-07 Herwig Jennewein Pharmaceutical compositions comprising an antibiotic
US8466096B2 (en) * 2007-04-26 2013-06-18 Afton Chemical Corporation 1,3,2-dioxaphosphorinane, 2-sulfide derivatives for use as anti-wear additives in lubricant compositions
ITMI20071628A1 (it) 2007-08-06 2007-11-05 Acs Dobfar Spa Sintesi di 3-alchenilcefalosporine e nuovi intermedi utili ad esse correlati
KR101058135B1 (ko) * 2008-04-04 2011-08-24 대웅바이오 주식회사 세프디니르 합성에 유용한 중간체 및 이를 이용하여세프디니르를 제조하는 방법
CN101481383B (zh) * 2008-12-31 2012-01-11 杭州奥默医药技术有限公司 头孢地尼酸式复盐化合物及制备方法
CN102020664B (zh) * 2010-11-30 2012-12-12 浙江工业大学 一种头孢地尼的合成方法
CN103319503A (zh) * 2013-06-09 2013-09-25 四川方向药业有限责任公司 一种头孢地尼的制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK162718C (da) * 1982-09-30 1992-05-11 Fujisawa Pharmaceutical Co Analogifremgangsmaade til fremstilling af 7-substitueret-3-vinyl-3-cephemforbindelser
IL99898A (en) * 1990-11-09 1996-10-31 Eisai Co Ltd 7-Noble-3- Compounds Transformed Carbamoylloxy
TW212181B (es) * 1992-02-14 1993-09-01 Hoechst Ag
EP0720611A1 (en) * 1994-07-22 1996-07-10 Antibioticos S.P.A. Glutaryl 7-aca derivatives and processes for obtaining them

Also Published As

Publication number Publication date
JP2000502700A (ja) 2000-03-07
US6093814A (en) 2000-07-25
EP0874853A1 (en) 1998-11-04
DE69621649T2 (de) 2002-09-19
WO1997024358A1 (en) 1997-07-10
DK0874853T3 (da) 2002-09-23
EP0874853B1 (en) 2002-06-05
JP3948628B2 (ja) 2007-07-25
PT874853E (pt) 2002-09-30
DE69621649D1 (de) 2002-07-11
ATE218572T1 (de) 2002-06-15

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