ITMI20071628A1 - Sintesi di 3-alchenilcefalosporine e nuovi intermedi utili ad esse correlati - Google Patents

Sintesi di 3-alchenilcefalosporine e nuovi intermedi utili ad esse correlati

Info

Publication number
ITMI20071628A1
ITMI20071628A1 IT001628A ITMI20071628A ITMI20071628A1 IT MI20071628 A1 ITMI20071628 A1 IT MI20071628A1 IT 001628 A IT001628 A IT 001628A IT MI20071628 A ITMI20071628 A IT MI20071628A IT MI20071628 A1 ITMI20071628 A1 IT MI20071628A1
Authority
IT
Italy
Prior art keywords
alchenylcephalosporines
synthesis
new intermediate
intermediate useful
useful related
Prior art date
Application number
IT001628A
Other languages
English (en)
Inventor
Mauro Filippi
Giovanni Fogliato
Antonio Manca
Riccardo Ambrogio Monguzzi
Bruno Maurizio Sala
Original Assignee
Acs Dobfar Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Acs Dobfar Spa filed Critical Acs Dobfar Spa
Priority to IT001628A priority Critical patent/ITMI20071628A1/it
Publication of ITMI20071628A1 publication Critical patent/ITMI20071628A1/it
Priority to EP08159182A priority patent/EP2030975A1/en
Priority to ZA200806049A priority patent/ZA200806049B/xx
Priority to CNA2008101454148A priority patent/CN101362769A/zh
Priority to KR1020080076693A priority patent/KR20090014985A/ko
Priority to BRPI0803893-7A priority patent/BRPI0803893A2/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/60—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 3 and 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/26—Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group
    • C07D501/34—Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group with the 7-amino radical acylated by carboxylic acids containing hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)
IT001628A 2007-08-06 2007-08-06 Sintesi di 3-alchenilcefalosporine e nuovi intermedi utili ad esse correlati ITMI20071628A1 (it)

Priority Applications (6)

Application Number Priority Date Filing Date Title
IT001628A ITMI20071628A1 (it) 2007-08-06 2007-08-06 Sintesi di 3-alchenilcefalosporine e nuovi intermedi utili ad esse correlati
EP08159182A EP2030975A1 (en) 2007-08-06 2008-06-27 CEFDINIR synthesis process
ZA200806049A ZA200806049B (en) 2007-08-06 2008-07-11 Cefdinir synthesis process
CNA2008101454148A CN101362769A (zh) 2007-08-06 2008-08-05 头孢地尼的合成方法
KR1020080076693A KR20090014985A (ko) 2007-08-06 2008-08-05 세프디니르의 합성방법
BRPI0803893-7A BRPI0803893A2 (pt) 2007-08-06 2008-08-05 processo da sìntese de cefdinir

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT001628A ITMI20071628A1 (it) 2007-08-06 2007-08-06 Sintesi di 3-alchenilcefalosporine e nuovi intermedi utili ad esse correlati

Publications (1)

Publication Number Publication Date
ITMI20071628A1 true ITMI20071628A1 (it) 2007-11-05

Family

ID=39951589

Family Applications (1)

Application Number Title Priority Date Filing Date
IT001628A ITMI20071628A1 (it) 2007-08-06 2007-08-06 Sintesi di 3-alchenilcefalosporine e nuovi intermedi utili ad esse correlati

Country Status (6)

Country Link
EP (1) EP2030975A1 (it)
KR (1) KR20090014985A (it)
CN (1) CN101362769A (it)
BR (1) BRPI0803893A2 (it)
IT (1) ITMI20071628A1 (it)
ZA (1) ZA200806049B (it)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101565427B (zh) * 2009-06-11 2011-04-27 浙江昂利康制药有限公司 头孢地尼的制备方法
CN102020664B (zh) * 2010-11-30 2012-12-12 浙江工业大学 一种头孢地尼的合成方法
CN103012433B (zh) * 2012-12-13 2015-06-24 珠海保税区丽珠合成制药有限公司 头孢地尼晶型b的制备方法
CN103554137B (zh) * 2013-10-31 2015-07-15 哈药集团制药总厂 一种头孢地尼微粉的制备方法
CN106279207A (zh) * 2016-08-15 2017-01-04 苏州中联化学制药有限公司 一种头孢地尼的合成方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA885709B (en) 1987-08-19 1989-04-26 Fujisawa Pharmaceutical Co Novel crystalline 7-(2-(2-aminothiazol-4-yl)-2-hydroxyiminoacetamido)-3-vinyl-3-cephem-4-carboxylic acid(syn isomer)
US4935508A (en) 1988-08-23 1990-06-19 Bristol-Myers Company Process for cephem prodrug esters
TW212181B (it) 1992-02-14 1993-09-01 Hoechst Ag
KR950013578B1 (ko) 1993-04-10 1995-11-09 주식회사럭키 신규 티아(디아)졸 초산의 반응성 티오포스페이트 유도체 및 그의 제조방법
US6093814A (en) 1995-12-27 2000-07-25 Hanmi Pharmaceutical Co., Ltd. Process for preparation of cefdinir
US5906098A (en) 1996-07-16 1999-05-25 Turbodyne Systems, Inc. Motor-generator assisted turbocharging systems for use with internal combustion engines and control method therefor
ITMI20020913A0 (it) 2002-04-29 2002-04-29 Acs Dobfar Spa Nuova forma cristallina del cefdinir
ITMI20022076A1 (it) * 2002-10-01 2004-04-02 Antibioticos Spa Sali di intermedi del cefdinir.

Also Published As

Publication number Publication date
ZA200806049B (en) 2009-10-28
EP2030975A1 (en) 2009-03-04
KR20090014985A (ko) 2009-02-11
CN101362769A (zh) 2009-02-11
BRPI0803893A2 (pt) 2009-06-16

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