DE60111834D1 - Verfahren zur herstellung von 3-amino-1,5-benzodiazepinderivaten - Google Patents

Verfahren zur herstellung von 3-amino-1,5-benzodiazepinderivaten

Info

Publication number
DE60111834D1
DE60111834D1 DE60111834T DE60111834T DE60111834D1 DE 60111834 D1 DE60111834 D1 DE 60111834D1 DE 60111834 T DE60111834 T DE 60111834T DE 60111834 T DE60111834 T DE 60111834T DE 60111834 D1 DE60111834 D1 DE 60111834D1
Authority
DE
Germany
Prior art keywords
preparation
amino
compound
benzodiazepine derivatives
acid addition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE60111834T
Other languages
English (en)
Other versions
DE60111834T2 (de
Inventor
David Colclough
Anne Hodgson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Glaxo Group Ltd
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Application granted granted Critical
Publication of DE60111834D1 publication Critical patent/DE60111834D1/de
Publication of DE60111834T2 publication Critical patent/DE60111834T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/12—1,5-Benzodiazepines; Hydrogenated 1,5-benzodiazepines

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DE60111834T 2000-04-05 2001-04-04 Verfahren zur herstellung von 3-amino-1,5-benzodiazepinderivaten Expired - Fee Related DE60111834T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB0008179.4A GB0008179D0 (en) 2000-04-05 2000-04-05 Chemical process
GB0008179 2000-04-05
PCT/EP2001/003820 WO2001077143A2 (en) 2000-04-05 2001-04-04 Process for the preparation of 3-amino-1, 5-benzodiazepine derivatives

Publications (2)

Publication Number Publication Date
DE60111834D1 true DE60111834D1 (de) 2005-08-11
DE60111834T2 DE60111834T2 (de) 2006-04-27

Family

ID=9889106

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60111834T Expired - Fee Related DE60111834T2 (de) 2000-04-05 2001-04-04 Verfahren zur herstellung von 3-amino-1,5-benzodiazepinderivaten

Country Status (9)

Country Link
US (1) US6673921B2 (de)
EP (1) EP1268517B1 (de)
JP (1) JP2003530404A (de)
AT (1) ATE299147T1 (de)
AU (1) AU2001256253A1 (de)
DE (1) DE60111834T2 (de)
ES (1) ES2241817T3 (de)
GB (1) GB0008179D0 (de)
WO (1) WO2001077143A2 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK2254873T3 (da) 2008-02-22 2014-06-30 Otsuka Pharma Co Ltd Benzodiazepinforbindelse og farmaceutisk sammensætning.
KR20120065360A (ko) * 2009-08-21 2012-06-20 오츠카 세이야쿠 가부시키가이샤 벤조［ｂ］［1,4］디아제핀-2,4-디온 화합물의 제조 방법
TWI481601B (zh) 2009-08-21 2015-04-21 Otsuka Pharma Co Ltd 含氮化合物及藥學組成物

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2641280B1 (fr) * 1988-12-29 1994-01-21 Roussel Uclaf Nouveaux derives de la 2,4-dioxo 2,3,4,5-tetrahydro 1h-1,5-benzodiazepine, leur procede de preparation et leur application comme medicaments
GB9308421D0 (en) * 1993-04-23 1993-06-09 Glaxo Spa Chemical compounds
ATE214056T1 (de) * 1993-12-28 2002-03-15 Shionogi & Co Benzodiazepinderivate
US5691331A (en) * 1995-06-07 1997-11-25 Merck & Co., Inc. N-(2,4-Dioxo-2,3,4,5-tetrahydro-1H-1,5-benzodiazepin-3yl) -3- amides

Also Published As

Publication number Publication date
WO2001077143A3 (en) 2002-01-24
GB0008179D0 (en) 2000-05-24
DE60111834T2 (de) 2006-04-27
WO2001077143A2 (en) 2001-10-18
ATE299147T1 (de) 2005-07-15
US20030158082A1 (en) 2003-08-21
EP1268517A2 (de) 2003-01-02
JP2003530404A (ja) 2003-10-14
US6673921B2 (en) 2004-01-06
EP1268517B1 (de) 2005-07-06
ES2241817T3 (es) 2005-11-01
AU2001256253A1 (en) 2001-10-23

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee