ATE214056T1 - Benzodiazepinderivate - Google Patents

Benzodiazepinderivate

Info

Publication number
ATE214056T1
ATE214056T1 AT95902983T AT95902983T ATE214056T1 AT E214056 T1 ATE214056 T1 AT E214056T1 AT 95902983 T AT95902983 T AT 95902983T AT 95902983 T AT95902983 T AT 95902983T AT E214056 T1 ATE214056 T1 AT E214056T1
Authority
AT
Austria
Prior art keywords
receptors
optionally substituted
cck
lower alkyl
conh
Prior art date
Application number
AT95902983T
Other languages
English (en)
Inventor
Sanji Hagishita
Susumu Kamata
Kaoru Seno
Nobuhiro Haga
Yasunobu Ishihara
Original Assignee
Shionogi & Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shionogi & Co filed Critical Shionogi & Co
Application granted granted Critical
Publication of ATE214056T1 publication Critical patent/ATE214056T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D243/00Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/121,5-Benzodiazepines; Hydrogenated 1,5-benzodiazepines
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
AT95902983T 1993-12-28 1994-12-19 Benzodiazepinderivate ATE214056T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP33616893 1993-12-28
PCT/JP1994/002132 WO1995018110A1 (fr) 1993-12-28 1994-12-19 Nouveau derive de benzodiazepine

Publications (1)

Publication Number Publication Date
ATE214056T1 true ATE214056T1 (de) 2002-03-15

Family

ID=18296379

Family Applications (1)

Application Number Title Priority Date Filing Date
AT95902983T ATE214056T1 (de) 1993-12-28 1994-12-19 Benzodiazepinderivate

Country Status (12)

Country Link
US (1) US5776929A (de)
EP (1) EP0728748B1 (de)
JP (1) JP3621416B2 (de)
CN (1) CN1073089C (de)
AT (1) ATE214056T1 (de)
AU (1) AU684871B2 (de)
CA (1) CA2177960A1 (de)
DE (1) DE69430068T2 (de)
ES (1) ES2173167T3 (de)
PT (1) PT728748E (de)
TW (1) TW334428B (de)
WO (1) WO1995018110A1 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5691331A (en) * 1995-06-07 1997-11-25 Merck & Co., Inc. N-(2,4-Dioxo-2,3,4,5-tetrahydro-1H-1,5-benzodiazepin-3yl) -3- amides
US6239131B1 (en) * 1996-12-10 2001-05-29 Zeria Pharmaceutical Co., Ltd. 1,5 Benzodiazepine derivatives
JP2000026434A (ja) 1998-06-05 2000-01-25 Zeria Pharmaceut Co Ltd 新規1,5−ベンゾジアゼピン誘導体
GB0008179D0 (en) * 2000-04-05 2000-05-24 Glaxo Group Ltd Chemical process
AU776283B2 (en) 1999-12-02 2004-09-02 Zeria Pharmaceutical Co., Ltd. Calcium salts of 1,5-benzodiazepine derivatives, process for producing the salts and drugs containing the same
EP2065046B1 (de) * 2007-11-30 2013-07-31 Kao Corporation GIP-Sekretionshemmer
JP5075254B2 (ja) 2011-01-07 2012-11-21 スノーデン株式会社 胃酸及びガストリンの産生を抑制する乳酸菌

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5408646A (en) * 1991-03-29 1995-04-18 International Business Machines Corp. Multipath torus switching apparatus
DE69319945T2 (de) * 1992-01-21 1999-03-11 Glaxo Wellcome Spa 1,5-Benzodiazepinderivate und deren Verwendung in Heilmittel
GB9201181D0 (en) * 1992-01-21 1992-03-11 Glaxo Spa Chemical compounds
AU688316B2 (en) * 1993-04-15 1998-03-12 Glaxo Wellcome Inc. 1,5 benzodiazepine derivatives having CCK and/or gastrin antagonistic activity
GB9307833D0 (en) * 1993-04-15 1993-06-02 Glaxo Inc Modulators of cholecystokinin and gastrin
GB9308421D0 (en) * 1993-04-23 1993-06-09 Glaxo Spa Chemical compounds

Also Published As

Publication number Publication date
DE69430068T2 (de) 2002-08-14
EP0728748A4 (de) 1997-03-19
CN1073089C (zh) 2001-10-17
TW334428B (en) 1998-06-21
CA2177960A1 (en) 1995-07-06
DE69430068D1 (de) 2002-04-11
PT728748E (pt) 2002-06-28
WO1995018110A1 (fr) 1995-07-06
EP0728748A1 (de) 1996-08-28
JP3621416B2 (ja) 2005-02-16
US5776929A (en) 1998-07-07
AU684871B2 (en) 1998-01-08
EP0728748B1 (de) 2002-03-06
CN1143362A (zh) 1997-02-19
AU1201195A (en) 1995-07-17
ES2173167T3 (es) 2002-10-16

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee