ES2156735A1 - Procedimiento de produccion de licopeno. - Google Patents

Procedimiento de produccion de licopeno.

Info

Publication number
ES2156735A1
ES2156735A1 ES009901271A ES9901271A ES2156735A1 ES 2156735 A1 ES2156735 A1 ES 2156735A1 ES 009901271 A ES009901271 A ES 009901271A ES 9901271 A ES9901271 A ES 9901271A ES 2156735 A1 ES2156735 A1 ES 2156735A1
Authority
ES
Spain
Prior art keywords
lycopen
production method
lycopene
production
addition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES009901271A
Other languages
English (en)
Other versions
ES2156735B1 (es
Inventor
Ana Teresa Marcos
De Castro Antonio Estrella
Bina Mehta
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Antibioticos SA
Original Assignee
Antibioticos SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to ES009901271A priority Critical patent/ES2156735B1/es
Application filed by Antibioticos SA filed Critical Antibioticos SA
Priority to DE60023693T priority patent/DE60023693T2/de
Priority to ES00935226T priority patent/ES2252009T3/es
Priority to EP00935226A priority patent/EP1184464B1/en
Priority to AT00935226T priority patent/ATE308622T1/de
Priority to PCT/ES2000/000202 priority patent/WO2000077234A2/es
Priority to JP2001503676A priority patent/JP3904924B2/ja
Priority to AU50792/00A priority patent/AU5079200A/en
Priority to CN00808484.XA priority patent/CN1252276C/zh
Publication of ES2156735A1 publication Critical patent/ES2156735A1/es
Application granted granted Critical
Publication of ES2156735B1 publication Critical patent/ES2156735B1/es
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P23/00—Preparation of compounds containing a cyclohexene ring having an unsaturated side chain containing at least ten carbon atoms bound by conjugated double bonds, e.g. carotenes

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Glass Compositions (AREA)
  • External Artificial Organs (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

Procedimiento de producción de licopeno. La presente invención se refiere a un nuevo procedimiento para la obtención de carotenoides, especialmente licopeno, a partir de cultivos sumergidos de hongos mucorales como Blakeslea. Se describe un método de fermentación que permite obtener un incremento en la producción de licopeno, basado en la adición de ácidos trispóricos. El proceso se lleva a cabo a partir de estirpes silvestres o mutantes de las mismas, en cultivo simple o mixto. La adición de ácidos trispóricos puede hacerse al inicio de la fermentación o durante la misma y su origen puede ser una preparación parcialmente purificada o una fuente no purificada de los mismos.
ES009901271A 1999-06-09 1999-06-09 Procedimiento de produccion de licopeno. Expired - Fee Related ES2156735B1 (es)

Priority Applications (9)

Application Number Priority Date Filing Date Title
ES009901271A ES2156735B1 (es) 1999-06-09 1999-06-09 Procedimiento de produccion de licopeno.
ES00935226T ES2252009T3 (es) 1999-06-09 2000-06-06 Metodo de produccion de licopeno.
EP00935226A EP1184464B1 (en) 1999-06-09 2000-06-06 Lycopen production method
AT00935226T ATE308622T1 (de) 1999-06-09 2000-06-06 Herstellungsverfahren für lycopen
DE60023693T DE60023693T2 (de) 1999-06-09 2000-06-06 Herstellungsverfahren für lycopen
PCT/ES2000/000202 WO2000077234A2 (es) 1999-06-09 2000-06-06 Procedimiento de produccion de licopeno
JP2001503676A JP3904924B2 (ja) 1999-06-09 2000-06-06 リコペンを製造する方法
AU50792/00A AU5079200A (en) 1999-06-09 2000-06-06 Lycopen production method
CN00808484.XA CN1252276C (zh) 1999-06-09 2000-06-06 生产番茄红素的方法

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES009901271A ES2156735B1 (es) 1999-06-09 1999-06-09 Procedimiento de produccion de licopeno.

Publications (2)

Publication Number Publication Date
ES2156735A1 true ES2156735A1 (es) 2001-07-01
ES2156735B1 ES2156735B1 (es) 2002-02-16

Family

ID=8308761

Family Applications (2)

Application Number Title Priority Date Filing Date
ES009901271A Expired - Fee Related ES2156735B1 (es) 1999-06-09 1999-06-09 Procedimiento de produccion de licopeno.
ES00935226T Expired - Lifetime ES2252009T3 (es) 1999-06-09 2000-06-06 Metodo de produccion de licopeno.

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES00935226T Expired - Lifetime ES2252009T3 (es) 1999-06-09 2000-06-06 Metodo de produccion de licopeno.

Country Status (8)

Country Link
EP (1) EP1184464B1 (es)
JP (1) JP3904924B2 (es)
CN (1) CN1252276C (es)
AT (1) ATE308622T1 (es)
AU (1) AU5079200A (es)
DE (1) DE60023693T2 (es)
ES (2) ES2156735B1 (es)
WO (1) WO2000077234A2 (es)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003056028A1 (es) * 2001-12-31 2003-07-10 Vitatene, S.A. Procedimiento mejorado de produccion de licopeno mediante la fermentacion de cepas seleccionadas de blakeslea trispora, formulaciones y usos del licopeno obtenido

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1392824B1 (en) 2001-06-06 2008-08-20 DSM IP Assets B.V. Improved isoprenoid production
RU2211862C2 (ru) * 2001-10-29 2003-09-10 Федеральное государственное унитарное предприятие "Государственный научно-исследовательский институт генетики и селекции промышленных микроорганизмов" (-) ШТАММ ГЕТЕРОТАЛЛИЧНОГО ФИКОМИЦЕТА Blakeslea trispora, ПРОДУЦИРУЮЩИЙ ЛИКОПИН В ПАРЕ С РАЗНЫМИ (+)ШТАММАМИ Blakeslea trispora, И СПОСОБ МИКРОБИОЛОГИЧЕСКОГО СИНТЕЗА ЛИКОПИНА
JP2006515516A (ja) * 2003-01-09 2006-06-01 ビーエーエスエフ　アクチェンゲゼルシャフト 遺伝子改変されたＢｌａｋｅｓｌｅａ属の生物を使用する、カロチノイドまたはそれらの前駆体を製造するための方法、上記方法によって製造されたカロチノイドまたはそれらの前駆体、ならびにそれらの使用
US20060099670A1 (en) * 2003-01-09 2006-05-11 Markus Matuschek Method for the genetic modification of organisms of the genus blakeslea, corresponding organisms and the use of the same
CN100335642C (zh) * 2005-03-16 2007-09-05 佛山市英迈瑞生物技术服务有限公司 基因重组毕赤酵母生产番茄红素的方法
CN102140052B (zh) * 2010-12-30 2013-12-18 南京工业大学 一种连续提取番茄红素的方法
CN102787158B (zh) 2011-05-20 2015-01-21 浙江医药股份有限公司新昌制药厂 一种发酵法生产天然β-胡萝卜素的方法和应用
CN102251008B (zh) * 2011-06-09 2013-05-29 北京化工大学 一种提高由三孢布拉氏霉菌生产番茄红素产量的方法
CN109280685B (zh) * 2017-07-21 2021-11-23 浙江医药股份有限公司新昌制药厂 通过增加天然类胡萝卜素发酵过程中溶氧生产天然类胡萝卜素的方法
CN108004272B (zh) * 2017-12-28 2021-09-21 嘉必优生物技术（武汉）股份有限公司 一种利用三孢布拉氏霉菌制备番茄红素的方法及番茄红素制品
GB202211084D0 (en) 2022-07-29 2022-09-14 Givaudan Sa Composition

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1034944A (en) * 1963-08-02 1966-07-06 Farmaceutici Italia Production of ª‰-carotene
GB1114043A (en) * 1964-09-23 1968-05-15 Upjohn Co Improvements in or relating to acid compounds and the manufacture thereof by a microbiological method

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1034944A (en) * 1963-08-02 1966-07-06 Farmaceutici Italia Production of ª‰-carotene
GB1114043A (en) * 1964-09-23 1968-05-15 Upjohn Co Improvements in or relating to acid compounds and the manufacture thereof by a microbiological method

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003056028A1 (es) * 2001-12-31 2003-07-10 Vitatene, S.A. Procedimiento mejorado de produccion de licopeno mediante la fermentacion de cepas seleccionadas de blakeslea trispora, formulaciones y usos del licopeno obtenido
ES2195758A1 (es) * 2001-12-31 2003-12-01 Antibioticos Sau Procedimiento mejorado de produccion de licopeno mediante la fermentacion de cepas seleccionadas de blakeslea trispora, formulaciones y usos del licopeno obtenido.
US7799540B2 (en) 2001-12-31 2010-09-21 Vitatene, S.A. Method of producing lycopene through the fermentation of selected strains of Blackeslea trispora, formulations and uses of the lycopene thus obtained

Also Published As

Publication number Publication date
ATE308622T1 (de) 2005-11-15
DE60023693D1 (de) 2005-12-08
ES2156735B1 (es) 2002-02-16
ES2252009T3 (es) 2006-05-16
EP1184464B1 (en) 2005-11-02
CN1353765A (zh) 2002-06-12
JP2003502052A (ja) 2003-01-21
JP3904924B2 (ja) 2007-04-11
CN1252276C (zh) 2006-04-19
EP1184464A2 (en) 2002-03-06
WO2000077234A2 (es) 2000-12-21
AU5079200A (en) 2001-01-02
WO2000077234A3 (es) 2001-02-08
DE60023693T2 (de) 2006-07-20

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