ES2145745T3 - Kit y metodo para realizar ensayos de enlazado. - Google Patents
Kit y metodo para realizar ensayos de enlazado.Info
- Publication number
- ES2145745T3 ES2145745T3 ES92916533T ES92916533T ES2145745T3 ES 2145745 T3 ES2145745 T3 ES 2145745T3 ES 92916533 T ES92916533 T ES 92916533T ES 92916533 T ES92916533 T ES 92916533T ES 2145745 T3 ES2145745 T3 ES 2145745T3
- Authority
- ES
- Spain
- Prior art keywords
- region
- substance
- analysis
- flow matrix
- immobilized
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54366—Apparatus specially adapted for solid-phase testing
- G01N33/54386—Analytical elements
- G01N33/54387—Immunochromatographic test strips
- G01N33/54388—Immunochromatographic test strips based on lateral flow
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/558—Immunoassay; Biospecific binding assay; Materials therefor using diffusion or migration of antigen or antibody
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5023—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures with a sample being transported to, and subsequently stored in an absorbent for analysis
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/505—Containers for the purpose of retaining a material to be analysed, e.g. test tubes flexible containers not provided for above
- B01L3/5055—Hinged, e.g. opposable surfaces
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/06—Auxiliary integrated devices, integrated components
- B01L2300/0627—Sensor or part of a sensor is integrated
- B01L2300/0663—Whole sensors
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/06—Auxiliary integrated devices, integrated components
- B01L2300/0672—Integrated piercing tool
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/06—Valves, specific forms thereof
- B01L2400/0677—Valves, specific forms thereof phase change valves; Meltable, freezing, dissolvable plugs; Destructible barriers
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/06—Valves, specific forms thereof
- B01L2400/0677—Valves, specific forms thereof phase change valves; Meltable, freezing, dissolvable plugs; Destructible barriers
- B01L2400/0683—Valves, specific forms thereof phase change valves; Meltable, freezing, dissolvable plugs; Destructible barriers mechanically breaking a wall or membrane within a channel or chamber
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/26—Conditioning of the fluid carrier; Flow patterns
- G01N30/38—Flow patterns
- G01N30/40—Flow patterns using back flushing
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/90—Plate chromatography, e.g. thin layer or paper chromatography
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/805—Test papers
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/81—Packaged device or kit
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/97—Test strip or test slide
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/974—Aids related test
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/975—Kit
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/805—Optical property
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/807—Apparatus included in process claim, e.g. physical support structures
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/807—Apparatus included in process claim, e.g. physical support structures
- Y10S436/809—Multifield plates or multicontainer arrays
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/807—Apparatus included in process claim, e.g. physical support structures
- Y10S436/81—Tube, bottle, or dipstick
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Hematology (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Analytical Chemistry (AREA)
- Clinical Laboratory Science (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Food Science & Technology (AREA)
- Physics & Mathematics (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Cell Biology (AREA)
- Biotechnology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Automatic Analysis And Handling Materials Therefor (AREA)
- Treatment Of Liquids With Adsorbents In General (AREA)
Abstract
SE PRESENTAN DISPOSITIVOS Y METODOS PARA LLEVAR A CABO UN ENSAYO EN EL QUE SE DETERMINA LA PRESENCIA O CANTIDAD DE UNA SUSTANCIA DE ANALISIS EN UNA MUESTRA DE FLUIDO A BASE DE DETECTAR EL ENLACE DE LA SUSTANCIA DE ANALISIS A AL MENOS UN REACTIVO DE CAPTURA DE LA SUSTANCIA DE ANALISIS INMOVILIZADO Y DE LAVAR EL MATERIAL NO ENLAZADO DEL REACTIVO DE CAPTURA DE LA SUSTANCIA DE ANALISIS INMOVILIZADO. LOS DISPOSITIVOS Y LOS METODOS CONSISTEN EN UNA MATRIZ DE FLUJO DE FASE SOLIDA ALARGADA, QUE INCLUYE CANALES CAPILARES CAPACES DE PRODUCIR EL MOVIMIENTO DEL FLUIDO CAPILAR E INCLUYE ADEMAS (1) UNA PRIMERA REGION ADAPTADA PARA RECIBIR LA MUESTRA DE FLUIDO, (II) UNA SEGUNDA REGION EN LA QUE SE INMOVILIZA EL REACTIVO DE CAPTURA DE LA SUSTANCIA DE ANALISIS, (III) UNA TERCERA REGION PARA LA APLICACION DE UN REACTIVO DE LAVADO CAPAZ DE ELIMINAR LAS SUSTANCIAS NO ENLAZADAS DE LA SEGUNDA REGION; Y (IV) UN DEPOSITO ABSORBENTE CON UNA ALTA CAPACIDAD DE VOLUMEN. LA SEGUNDA REGION SE ENCUENTRA COLOCADA ENTRE MEDIAS DE LA PRIMERA Y LA TERCERA REGION Y ENTRE MEDIAS DEL DEPOSITO ABSORBENTE Y LA TERCERA REGION. EL DISPOSITIVO INCLUYE TAMBIEN ELEMENTOS PARA DETECTAR LA SUSTANCIA DE ANALISIS ENLAZADA EN LA SEGUNDA REGION. LA MATRIZ DE FLUJO Y LAS REGIONES DE LA MISMA TIENEN UN TAMAÑO Y SE ENCUENTRAN COLOCADAS DE UNA MANERA TALES QUE PUEDAN PROVOCAR QUE LA MUESTRA DE FLUIDO FLUYA INICIALMENTE A LO LARGO DE LA MATRIZ DE FLUJO ALARGADA EN UNA DIRECCION HACIA Y A TRAVES DE LA SEGUNDA REGION, Y QUE POSTERIORMENTE, EL REACTIVO LIQUIDO FLUYA A LO LARGO DE LA MATRIZ DE FLUJO ALARGADA EN UNA SEGUNDA DIRECCION OPUESTA A LA PRIMERA, A TRAVES DE LA SEGUNDA REGION Y ENTRE EN EL DEPOSITO ABSORBENTE, ARRASTRANDO CON EL LAS SUSTANCIAS NO ENLAZADAS.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US07/738,321 US5726010A (en) | 1991-07-31 | 1991-07-31 | Reversible flow chromatographic binding assay |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2145745T3 true ES2145745T3 (es) | 2000-07-16 |
Family
ID=24967509
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES92916533T Expired - Lifetime ES2145745T3 (es) | 1991-07-31 | 1992-07-31 | Kit y metodo para realizar ensayos de enlazado. |
Country Status (7)
Country | Link |
---|---|
US (3) | US5726010A (es) |
EP (1) | EP0600929B1 (es) |
JP (1) | JP3309977B2 (es) |
CA (1) | CA2113351C (es) |
DE (1) | DE69230884T2 (es) |
ES (1) | ES2145745T3 (es) |
WO (1) | WO1993003176A1 (es) |
Families Citing this family (182)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
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ATE231971T1 (de) * | 1996-09-27 | 2003-02-15 | Inverness Medical Switzerland | Test-kit und vorrichtungen |
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US6348573B1 (en) | 1998-04-27 | 2002-02-19 | The Regents Of The University Of Michigan | Compositions and methods for identifying apoptosis signaling pathway inhibitors and activators |
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-
1991
- 1991-07-31 US US07/738,321 patent/US5726010A/en not_active Expired - Lifetime
-
1992
- 1992-07-31 CA CA002113351A patent/CA2113351C/en not_active Expired - Lifetime
- 1992-07-31 DE DE69230884T patent/DE69230884T2/de not_active Expired - Lifetime
- 1992-07-31 JP JP50374093A patent/JP3309977B2/ja not_active Expired - Lifetime
- 1992-07-31 EP EP92916533A patent/EP0600929B1/en not_active Expired - Lifetime
- 1992-07-31 ES ES92916533T patent/ES2145745T3/es not_active Expired - Lifetime
- 1992-07-31 WO PCT/US1992/006348 patent/WO1993003176A1/en active IP Right Grant
-
1995
- 1995-06-07 US US08/487,469 patent/US5726013A/en not_active Expired - Lifetime
- 1995-06-07 US US08/476,805 patent/US5750333A/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
WO1993003176A1 (en) | 1993-02-18 |
JP3309977B2 (ja) | 2002-07-29 |
EP0600929A1 (en) | 1994-06-15 |
DE69230884T2 (de) | 2000-10-05 |
US5726013A (en) | 1998-03-10 |
EP0600929A4 (en) | 1996-01-17 |
DE69230884D1 (de) | 2000-05-11 |
US5750333A (en) | 1998-05-12 |
US5726010A (en) | 1998-03-10 |
CA2113351C (en) | 2005-09-27 |
JPH06510602A (ja) | 1994-11-24 |
CA2113351A1 (en) | 1993-02-18 |
EP0600929B1 (en) | 2000-04-05 |
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