ES2106326T3 - Reactor desechable para la analitica inmunologica en fase solida y procedimiento para la medicion de componentes determinables mediante una reaccion inmunologica. - Google Patents

Reactor desechable para la analitica inmunologica en fase solida y procedimiento para la medicion de componentes determinables mediante una reaccion inmunologica.

Info

Publication number
ES2106326T3
ES2106326T3 ES93905315T ES93905315T ES2106326T3 ES 2106326 T3 ES2106326 T3 ES 2106326T3 ES 93905315 T ES93905315 T ES 93905315T ES 93905315 T ES93905315 T ES 93905315T ES 2106326 T3 ES2106326 T3 ES 2106326T3
Authority
ES
Spain
Prior art keywords
immunological
solid phase
substrate
analytics
procedure
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES93905315T
Other languages
English (en)
Inventor
Ursula Erhardt
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ABION oHG
Abion Beteiligungs und Verwaltungs GmbH
Original Assignee
ABION oHG
Abion Beteiligungs und Verwaltungs GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ABION oHG, Abion Beteiligungs und Verwaltungs GmbH filed Critical ABION oHG
Application granted granted Critical
Publication of ES2106326T3 publication Critical patent/ES2106326T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/60—Construction of the column
    • G01N30/6091—Cartridges
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/60—Construction of the column
    • G01N30/6052—Construction of the column body
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/60—Construction of the column
    • G01N30/6034—Construction of the column joining multiple columns
    • G01N30/6039—Construction of the column joining multiple columns in series

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)

Abstract

LA PRESENTE INVENCION SE REFIERE A UN RECIPIENTE DE REACCION DE UNA VIA, ABIERTO EN AMBOS EXTREMOS, PARA ANALISIS INMUNOLOGICO DE FASE SOLIDA, CON AL MENOS UN COMPONENTE REACTIVO INMUNOLOGICAMENTE APLICADO SOBRE UN SUBSTRATO CON UNA SUPERFICIE ACTIVA O ACTIVADA. EL COMPONENTE REACTIVO INDICADO DISPONE DE UNA DENSIDAD DE CARGA TAL, QUE EL CONSTITUYENTE A SER DETERMINADO ENLAZA CUANTITATIVAMENTE (ENLACE DE EQUILIBRIO) AL CONSTITUYENTE REACTIVO ANTES DE QUE EL LIQUIDO QUE FLUYE DEJE EL SUBSTRATO; SIENDO EL VOLUMEN DEL LECHO DE SUBSTRATO HASTA 600 MICROLITROS, Y LA VELOCIDAD DEL FLUJO DEL LIQUIDO A PARTIR DEL LECHO DE SUBSTRATO SE DETERMINA DE FORMA CORRESPONDIENTE. EL RECIPIENTE DE REACCION DE UNA VIA PUEDE SER UTILIZADO PARA MEDIR CONSTITUYENTES QUE PUEDEN SER DETERMINADOS SOBRE LA BASE DE REACCIONES INMUNES.
ES93905315T 1992-03-18 1993-03-08 Reactor desechable para la analitica inmunologica en fase solida y procedimiento para la medicion de componentes determinables mediante una reaccion inmunologica. Expired - Lifetime ES2106326T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4208732A DE4208732C2 (de) 1992-03-18 1992-03-18 Einwegreaktionsgefäß für die Festphasenimmunanalytik und Verfahren zur Messung von über Immunreaktionen bestimmbaren Komponenten

Publications (1)

Publication Number Publication Date
ES2106326T3 true ES2106326T3 (es) 1997-11-01

Family

ID=6454401

Family Applications (1)

Application Number Title Priority Date Filing Date
ES93905315T Expired - Lifetime ES2106326T3 (es) 1992-03-18 1993-03-08 Reactor desechable para la analitica inmunologica en fase solida y procedimiento para la medicion de componentes determinables mediante una reaccion inmunologica.

Country Status (17)

Country Link
EP (1) EP0634015B1 (es)
JP (1) JPH07504983A (es)
KR (1) KR100270209B1 (es)
AT (1) ATE158081T1 (es)
AU (1) AU675781B2 (es)
BR (1) BR9306086A (es)
CA (1) CA2131007A1 (es)
CZ (1) CZ217294A3 (es)
DE (2) DE4208732C2 (es)
ES (1) ES2106326T3 (es)
FI (1) FI944320A0 (es)
HU (1) HUT74558A (es)
NO (1) NO943462D0 (es)
NZ (1) NZ249491A (es)
RU (1) RU2115122C1 (es)
SK (1) SK109894A3 (es)
WO (1) WO1993019368A1 (es)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH09507577A (ja) * 1994-01-13 1997-07-29 アビオン ベタイリゲンズ− ウント ベルワルトゥングスゲゼルシャフト ミット ベシュレンクテル ハフツング 多対象同時測定用反応カラムと方法
DE19528847C2 (de) * 1995-08-05 1997-12-11 Biotest Ag Affinitätschromatographisches Verfahren zum Nachweis von Antigenen und/oder Antikörpern
DE19543240A1 (de) * 1995-11-20 1997-05-22 Abion Ohg Einwegauftragsvorrichtung sowie Kit
CN1214771A (zh) * 1996-01-30 1999-04-21 阿比翁参股及管理股份有限公司 用于固相分析的一种可流载载体材料
GB9708961D0 (en) * 1997-05-02 1997-06-25 Ringel Karl Peter Immunoassay
WO1999024138A1 (en) * 1997-11-12 1999-05-20 Life Technologies, Inc. Device and methods for purifying biological molecules using low volumes of chromatographic and adsorptive media
DE29803712U1 (de) * 1998-03-04 1998-04-23 Macherey, Nagel GmbH & Co. Handelsgesellschaft, 52355 Düren Vorrichtung zur Behandlung von Biomolekülen
US6177009B1 (en) 1998-04-03 2001-01-23 Macherey, Nagel Gmbh & Co. Apparatus for treating biomolecules
DE10057195A1 (de) * 2000-11-17 2002-05-23 Robert Loesel Reaktionsgefäß mit Membranboden
DE10247430A1 (de) * 2002-10-11 2004-04-29 Fresenius Hemocare Gmbh Verfahren zur Bestimmung des Gehalts an Endotoxinen in Flüssigkeiten
DE102007025311A1 (de) 2007-05-30 2008-12-04 Senova Gesellschaft für Biowissenschaft und Technik mbH Quantitativer heterogener schneller Bindungsassay mit breitem dynamischen Bereich und einfacher photometrischer Detektion
GB0802355D0 (en) * 2008-02-08 2008-03-12 Univ Greenwich Modified SPE adsorbent cartridge
EP2264461A1 (de) 2009-06-19 2010-12-22 FZMB GmbH Forschungszentrum für Medizintechnik und Biotechnologie Vorrichtung zur Durchführung eines affinitätschromatographischen Probentests
WO2012016720A1 (en) * 2010-08-05 2012-02-09 Vibod Gmbh New columns for incubation and isolation of chemical and/or biological samples
EP2487490A1 (de) 2011-02-11 2012-08-15 FZMB GmbH Forschungszentrum für Medizintechnik und Biotechnologie Heterogener Bindungsassay mit verbesserter optischer Auswertbarkeit oder poröse Festphase für Bindungsassays mit verbesserter optischer Auswertbarkeit
JP6231989B2 (ja) 2011-11-10 2017-11-15 バイオファイア・ダイアグノスティクス，リミテッド・ライアビリティ・カンパニー 充填バイアル

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1907014A1 (de) * 1969-02-12 1970-09-03 Haller Dr Wolfgang Verfahren zur Trennung von Blutkomponenten,insbesondere von immunologisch aktiven Globulinen,von anderen Komponenten
US4039652A (en) * 1973-10-11 1977-08-02 Miles Laboratories, Inc. Column method of immunoassay employing an immobilized binding partner
US4151254A (en) * 1975-06-16 1979-04-24 Union Carbide Corporation Adsorption columns for use in radioimmunoassays
US4145406A (en) * 1977-04-11 1979-03-20 Miles Laboratories, Inc. Specific binding - adsorbent assay method and test means
SE458643B (sv) * 1984-12-07 1989-04-17 Pharmacia Ab Anordning med kolonnelement uppdelat i provparti och referenspatri
JPH087217B2 (ja) * 1986-04-09 1996-01-29 オリンパス光学工業株式会社 アフイニテイ−クロマトグラフイ−を応用した免疫学的測定方法
JPH07119769B2 (ja) * 1986-10-01 1995-12-20 株式会社日立製作所 自動分析装置
DE3717211A1 (de) * 1987-05-22 1988-12-01 Diagen Inst Molekularbio Vorrichtung und verfahren zur trennung und reinigung von molekuelen
US4892710A (en) * 1987-07-07 1990-01-09 Bioprobe International, Inc. Cartridge assembly with multi-purpose closure tubing
DD268161A1 (de) * 1987-11-27 1989-05-24 Staatliches Inst Fuer Immunpra Verfahren zur herstellung von bakteriellen antigenen
GB8928501D0 (en) * 1989-12-18 1990-02-21 Unilever Plc Reagents
US5183740A (en) * 1990-02-23 1993-02-02 The United States Of America As Represented By The Secretary Of The Navy Flow immunosensor method and apparatus
DE4126436A1 (de) * 1990-09-17 1992-03-19 Abion Ohg Einwegreaktionsgefaess fuer die festphasenimmunanalytik und verfahren zur messung von ueber immunreaktionen bestimmbaren komponenten

Also Published As

Publication number Publication date
NZ249491A (en) 1996-06-25
DE4208732C2 (de) 1995-04-27
WO1993019368A1 (de) 1993-09-30
NO943462L (no) 1994-09-16
DE4208732A1 (de) 1993-09-30
DE59307345D1 (de) 1997-10-16
HU9402654D0 (en) 1994-11-28
KR950701076A (ko) 1995-02-20
KR100270209B1 (ko) 2001-01-15
ATE158081T1 (de) 1997-09-15
FI944320A (fi) 1994-09-16
BR9306086A (pt) 1997-11-18
CA2131007A1 (en) 1993-09-30
JPH07504983A (ja) 1995-06-01
CZ217294A3 (en) 1995-02-15
AU3631693A (en) 1993-10-21
SK109894A3 (en) 1995-05-10
AU675781B2 (en) 1997-02-20
RU94041215A (ru) 1996-10-10
HUT74558A (en) 1997-01-28
EP0634015B1 (de) 1997-09-10
NO943462D0 (no) 1994-09-16
RU2115122C1 (ru) 1998-07-10
FI944320A0 (fi) 1994-09-16
EP0634015A1 (de) 1995-01-18

Similar Documents

Publication Publication Date Title
ES2106326T3 (es) Reactor desechable para la analitica inmunologica en fase solida y procedimiento para la medicion de componentes determinables mediante una reaccion inmunologica.
FR2634892B1 (fr) Dispositif pour la realisation d'analyses biologiques par detection immuno-enzymatique d'anticorps ou d'antigenes dans un serum
CS930287A2 (en) Testing carrier for body liquids' components analytic determination
JPS6472066A (en) Assay device provided with ports
FR2364680A1 (fr) Dispositif et procede de filtration
ATE117804T1 (de) Festphasen-test zur verwendung mit einem physikalischen entwickler.
CH0713576H1 (fr) Dispositif servant a la concentration des elements traces dans un liquide
NO882204D0 (no) Ett-trinns immuntest for bestemmelse av antigenspesifikke antistoffer fra en av immunoglobulinklassene a, m, d eller e og dertil egnet middel.
DE69017471D1 (de) Feststoff-phase-interferometrisches immunotestsystem.
DK233589D0 (da) Fremgangsmaade til bestemmelse af et immunologisk paaviseligt stof og en dertil egnet reaktionsbeholder
DK199783A (da) Immunoglobulin-halvmolekyler og fremgangsmaade til fremstilling af hybrid-antistoffer
JPS57196153A (en) Analysis element
AU618137B2 (en) Process for the determination of antibodies which are class-specific for an antigen and a reagent for carrying out the process
ATE157454T1 (de) Testvorrichtung zur bestimmung von einer in einer körperlichen flüssigkeit enthaltenen verbindung
CA2145005A1 (en) Monoclonal antibodies specific for tcf-ii
JPS56130657A (en) Determination method and device for antiacetylcholine receptor antibody
KR900005997A (ko) 인간 세포 독성 t-세포 클론 및 그에 대한 항체
NO154675C (no) Fremgangsmaate og anordning for bestemmelse av konsentrasjonen av en bestanddel bundet til partikler som baeres i et flytende medium.
NO172549C (no) Monoklonalt humanurokinase-antistoff, immunoabsorberende middel for rensing av humanurokinase samt anvendelse av antistoffet for detektering av humanurokinase
JPS5594636A (en) Microcapsule for antigen-antibody reaction and detecting method for antigen-antibody reaction using said microcapsule
CA2081879A1 (en) Monoclonal antibodies to polyacrylate polymers
DK0558361T3 (da) Sensibiliserede erythrocytter, fremgangsmåde til fremstilling heraf og anvendelse heraf
EP0394021A3 (en) Diagnostic device with porous, absorbent single element
JPS641961A (en) Immunological measurement
JPS6321559A (ja) ハプテンの酵素免疫測定法

Legal Events

Date Code Title Description
FG2A Definitive protection

Ref document number: 634015

Country of ref document: ES