ES2096413T3 - Derivado de acido 5-amino-8-metil-7-pirrolidinilquinoleina-3-carboxilico. - Google Patents

Derivado de acido 5-amino-8-metil-7-pirrolidinilquinoleina-3-carboxilico.

Info

Publication number
ES2096413T3
ES2096413T3 ES94304449T ES94304449T ES2096413T3 ES 2096413 T3 ES2096413 T3 ES 2096413T3 ES 94304449 T ES94304449 T ES 94304449T ES 94304449 T ES94304449 T ES 94304449T ES 2096413 T3 ES2096413 T3 ES 2096413T3
Authority
ES
Spain
Prior art keywords
group
compounds
hydrogen atom
pirrolidinylquinolein
amino
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES94304449T
Other languages
English (en)
Spanish (es)
Inventor
Yasuo Ito
Hideo Kato
Singo Yasuda
Noriyuki Kado
Toshihiko Yoshida
Yoichi Yamamoto
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Abbott Japan Co Ltd
Original Assignee
Hokuriku Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hokuriku Pharmaceutical Co Ltd filed Critical Hokuriku Pharmaceutical Co Ltd
Application granted granted Critical
Publication of ES2096413T3 publication Critical patent/ES2096413T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
    • C07D215/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Quinoline Compounds (AREA)
  • Epoxy Resins (AREA)
  • Medicinal Preparation (AREA)
  • Pyrrole Compounds (AREA)
ES94304449T 1993-08-27 1994-06-20 Derivado de acido 5-amino-8-metil-7-pirrolidinilquinoleina-3-carboxilico. Expired - Lifetime ES2096413T3 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP23431093 1993-08-27
JP28627293 1993-10-22
JP7631894 1994-03-24

Publications (1)

Publication Number Publication Date
ES2096413T3 true ES2096413T3 (es) 1997-03-01

Family

ID=27302121

Family Applications (1)

Application Number Title Priority Date Filing Date
ES94304449T Expired - Lifetime ES2096413T3 (es) 1993-08-27 1994-06-20 Derivado de acido 5-amino-8-metil-7-pirrolidinilquinoleina-3-carboxilico.

Country Status (23)

Country Link
US (1) US5547962A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
EP (1) EP0641793B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
JP (1) JP2673937B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
KR (1) KR100218807B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CN (1) CN1048242C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AT (1) ATE144508T1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AU (1) AU676729B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CA (1) CA2126118C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CZ (1) CZ286524B6 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DE (1) DE69400791T2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DK (1) DK0641793T3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
ES (1) ES2096413T3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
FI (1) FI113174B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
GR (1) GR3021715T3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
HU (1) HU221952B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IL (1) IL110060A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
MY (1) MY111702A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
NO (1) NO305515B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
NZ (1) NZ260851A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
PL (1) PL175870B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
SG (1) SG52147A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
TW (1) TW252107B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
UA (1) UA39859C2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

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CN1183778A (zh) * 1995-01-24 1998-06-03 北陆制药株式会社 喹啉羧酸衍生物
US6121285A (en) 1995-11-22 2000-09-19 Daiichi Pharmaceutical Co., Ltd. Substituted aminocycloalkylpyrrolidine derivatives and cis-substituted aminocycloalkylpyrrolidine derivatives
NZ503740A (en) 1997-09-15 2002-09-27 Procter & Gamble Antimicrobial quinolones, their compositions and uses
US6387928B1 (en) 1997-09-15 2002-05-14 The Procter & Gamble Co. Antimicrobial quinolones, their compositions and uses
US6531624B1 (en) 1998-11-18 2003-03-11 Asahi Glass Company Ltd. Aminoacrylic acid derivatives and process for producing the same
CA2367373C (en) 1999-03-17 2011-09-20 Daiichi Pharmaceutical Co., Ltd. Medicinal compositions
DE60135640D1 (de) * 2000-02-09 2008-10-16 Daiichi Sankyo Co Ltd Rielle mittel die pyridincarbonsäuren als aktiven wirkstoff enthalten
US6825353B2 (en) 2000-02-25 2004-11-30 Daiichi Pharmaceutical Co., Ltd. Process for producing quinolonecarboxylic acids and intermediates thereof
CN1426399A (zh) * 2000-02-25 2003-06-25 第一制药株式会社 喹诺酮甲酸及其中间体的制备方法
KR20010044286A (ko) * 2001-02-01 2001-06-05 남근수 알킬-3-(2,6-디할로겐-5-플루오로)-옥소-3-피리딘프로피오네이트의 제조방법
US7928232B2 (en) * 2005-05-20 2011-04-19 Daiichi Sankyo Company, Limited Method for producing asymmetric tetrasubstituted carbon atom-containing compound
JP5073497B2 (ja) * 2005-09-28 2012-11-14 第一三共株式会社 テトラ置換−５−アザスピロ［２．４］へプタン誘導体の製法およびその光学活性中間体
ATE507219T1 (de) * 2006-03-28 2011-05-15 Warner Chilcott Co Llc Malatsalze und polymorphe von (3s,5s)-7-ä3-amino- 5-methyl-piperidinylü-1-cyclopropyl-1,4-dihydro 8-methoxy-4-oxo-3-chinolincarbonsäure
US7528264B2 (en) * 2006-03-28 2009-05-05 The Procter & Gamble Company Hydride reduction process for preparing quinolone intermediates
BRPI0709220A2 (pt) * 2006-03-28 2011-07-12 Procter & Gamble processo de acoplamento para preparo de intermediários de quinolona
TWI362386B (en) 2007-03-30 2012-04-21 Daiichi Sankyo Co Ltd A production method for the qunolon-carboxylic acid derivative
FR2928150A1 (fr) * 2008-02-29 2009-09-04 Vetoquinol Sa Sa Nouveaux derives 7-substitues de 3-carboxy-oxadiazino-quinolones, leur preparation et leur application comme anti-bacteriens

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IE58742B1 (en) * 1984-07-20 1993-11-05 Warner Lambert Co Substituted-9-fluoro-3-methyl-7-oxo-2,3-dihydro-7h-pyrido[1,2,3-de] [1,4]benzoxauine-6-carboxylic acids; sibstituted-5-amino-6-6fluoro-4-oxo.1,4-dihydroquinoline-3 carboxylic acids; substituted-5-amino-6-fluoro-1,4-dihydro-4-oxo-1.8-naphthyridine-3-carboxylic acids; derivatives thereof; pharmaceutical compositions comprising the compounds; and processes for producing the compounds
JPH0635457B2 (ja) * 1985-06-28 1994-05-11 杏林製薬株式会社 ピリドンカルボン酸誘導体およびその製造方法
DE3608745A1 (de) * 1985-07-24 1987-01-29 Bayer Ag Bakterizide zubereitungen zur anwendung auf dem gebiet der veterinaermedizin
JPH0637489B2 (ja) * 1985-09-21 1994-05-18 杏林製薬株式会社 キノロンカルボン酸誘導体およびその製造方法
JPH089597B2 (ja) * 1986-01-21 1996-01-31 杏林製薬株式会社 選択毒性に優れた８‐アルコキシキノロンカルボン酸およびその塩並びにその製造方法
JPS62215572A (ja) * 1986-03-17 1987-09-22 Kyorin Pharmaceut Co Ltd キノロンカルボン酸誘導体
EP0242789A3 (en) * 1986-04-25 1990-09-05 Dainippon Pharmaceutical Co., Ltd. Novel quinoline derivates and processes for preparation thereof
IL83049A (en) * 1986-07-04 1991-12-12 Chemie Linz Ag 4-quinolinone-3-carboxylic acid derivatives,their manufacture and pharmaceutical compositions containing them
US4771055A (en) * 1986-07-28 1988-09-13 Warner-Lambert Company 7-[[3-(aminomethyl)-3-alkyl]-1-pyrrolidinyl]-quinoline-carboxylic acids
JPS63152318A (ja) * 1986-08-07 1988-06-24 Dainippon Pharmaceut Co Ltd 抗マイコプラズマ剤
US5190955A (en) * 1987-01-28 1993-03-02 Bayer Aktiengesellschaft Antibacterial 8-cyano-1-cyclopropyl-1,4-dihydro-4-oxo-3-quinolinecarboxylic acids
DE3702393A1 (de) * 1987-01-28 1988-08-11 Bayer Ag 8-cyano-1-cyclopropyl-1,4-dihydro-4-oxo- 3-chinolincarbonsaeuren, verfahren zu ihrer herstellung und diese enthaltende antibakterielle mittel
DE3711193A1 (de) * 1987-04-02 1988-10-13 Bayer Ag 5-substituierte chinolon- und naphthyridoncarbonsaeure-derivate
JPS63275567A (ja) * 1987-05-07 1988-11-14 Dainippon Pharmaceut Co Ltd 新規キノリン誘導体、そのエステルおよびその塩
IL88003A (en) * 1987-10-16 1992-11-15 Dainippon Pharmaceutical Co Quinoline derivatives,their preparation and pharmaceutical compositions containing them
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US5286723A (en) * 1988-08-31 1994-02-15 Daiichi Seiyaku Co., Ltd. Spiro compound
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US5328908A (en) * 1988-10-24 1994-07-12 Procter & Gamble Pharmaceuticals, Inc. Antimicrobial quinolone thioureas
CA2012063A1 (en) * 1989-03-15 1990-09-15 Hirosato Kondo Quinolinecarboxylic acid derivatives and antibacterial agent containing the same
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DE3910920A1 (de) * 1989-04-05 1990-10-11 Bayer Ag Enantiomerenreine 7-(3-amino-1-pyrrolidinyl)-chinolon- und -naphthyridoncarbonsaeuren
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KR950014567B1 (ko) * 1991-08-01 1995-12-08 주식회사대웅제약 신규한 퀴놀론 카르복실산 유도체

Also Published As

Publication number Publication date
JPH07309864A (ja) 1995-11-28
FI113174B (fi) 2004-03-15
CA2126118A1 (en) 1995-02-28
HU221952B1 (hu) 2003-03-28
EP0641793A1 (en) 1995-03-08
FI942976A0 (fi) 1994-06-21
AU6487094A (en) 1995-03-09
CZ157494A3 (en) 1995-10-18
US5547962A (en) 1996-08-20
HUT67259A (en) 1995-03-28
JP2673937B2 (ja) 1997-11-05
NO942309L (no) 1995-02-28
AU676729B2 (en) 1997-03-20
PL304063A1 (en) 1995-03-06
CA2126118C (en) 2001-02-06
IL110060A (en) 1999-10-28
HU9401954D0 (en) 1994-09-28
MY111702A (en) 2000-11-30
NO942309D0 (no) 1994-06-17
NO305515B1 (no) 1999-06-14
TW252107B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1995-07-21
PL175870B1 (pl) 1999-02-26
ATE144508T1 (de) 1996-11-15
KR100218807B1 (ko) 1999-09-01
SG52147A1 (en) 1998-09-28
IL110060A0 (en) 1994-10-07
GR3021715T3 (en) 1997-02-28
FI942976A7 (fi) 1995-02-28
DE69400791D1 (de) 1996-11-28
CN1048242C (zh) 2000-01-12
UA39859C2 (uk) 2001-07-16
NZ260851A (en) 1996-03-26
EP0641793B1 (en) 1996-10-23
DK0641793T3 (da) 1996-11-25
KR950005823A (ko) 1995-03-20
CZ286524B6 (cs) 2000-05-17
CN1117491A (zh) 1996-02-28
DE69400791T2 (de) 1997-03-06

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