ES2111086T3 - Compuestos triciclicos anfoteros como agentes antihistaminicos y antialergicos. - Google Patents

Compuestos triciclicos anfoteros como agentes antihistaminicos y antialergicos.

Info

Publication number
ES2111086T3
ES2111086T3 ES93102518T ES93102518T ES2111086T3 ES 2111086 T3 ES2111086 T3 ES 2111086T3 ES 93102518 T ES93102518 T ES 93102518T ES 93102518 T ES93102518 T ES 93102518T ES 2111086 T3 ES2111086 T3 ES 2111086T3
Authority
ES
Spain
Prior art keywords
antihistamine
same
tricyclic compounds
antiallergic agents
disclosed
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES93102518T
Other languages
English (en)
Inventor
Yasuo Ito
Hideo Kato
Shingo Yasuda
Noriyuki Kado
Nobuhiko Iwasaki
Hiroyuki Nishino
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Abbott Japan Co Ltd
Original Assignee
Hokuriku Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hokuriku Pharmaceutical Co Ltd filed Critical Hokuriku Pharmaceutical Co Ltd
Application granted granted Critical
Publication of ES2111086T3 publication Critical patent/ES2111086T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/16—Otologicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Pulmonology (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Cosmetics (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Steroid Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

SE PRESENTA UN NUEVO COMPUESTO TRICICLICO ANFOTERICO REPRESENTADO POR LA SIGUIENTE FORMULA: EN LA QUE R1 REPRESENTA UN ATOMO DE HIDROGENO O UN ATOMO DE HALOGENO; X REPRESENTA -O-, -CH2O-, O -CH2-; E Y REPRESENTA UN GRUPO DE ALQUILENO C2-C5 QUE PUEDE SER OPCIONALMENTE SUSTITUIDO CON UN GRUPO DE ALQUIL INFERIOR; ASIMISMO SE PRESENTAN LAS SALES FARMACOLOGICAMENTE ACEPTABLES DEL COMPUESTO. TAMBIEN SE PRESENTA UN METODO PARA PREPARAR EL MISMO, UNA COMPOSICION FARMACEUTICA QUE COMPRENDA EL MISMO COM AGENTE ANTIALERGICO Y UN AGENTE PARA EL ASMA BRONQUIAL, ASI COMO UN METODO PARA EL TRATAMIENTO DE UNA ENFERMEDAD ALERGIDA O DE ASMA BRONQUIAL QUE COMPRENDE LA ADMINISTRACION DEL MISMO.
ES93102518T 1992-02-20 1993-02-18 Compuestos triciclicos anfoteros como agentes antihistaminicos y antialergicos. Expired - Lifetime ES2111086T3 (es)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
JP6940492 1992-02-20
JP13760592 1992-05-01
JP13760292 1992-05-01
JP27350692 1992-09-18
JP32146792 1992-11-06

Publications (1)

Publication Number Publication Date
ES2111086T3 true ES2111086T3 (es) 1998-03-01

Family

ID=27524183

Family Applications (1)

Application Number Title Priority Date Filing Date
ES93102518T Expired - Lifetime ES2111086T3 (es) 1992-02-20 1993-02-18 Compuestos triciclicos anfoteros como agentes antihistaminicos y antialergicos.

Country Status (10)

Country Link
US (1) US5334594A (es)
EP (1) EP0556813B1 (es)
JP (1) JP2974529B2 (es)
KR (1) KR0140504B1 (es)
AT (1) ATE160566T1 (es)
AU (1) AU655869B2 (es)
CA (1) CA2089207C (es)
DE (1) DE69315363T2 (es)
DK (1) DK0556813T3 (es)
ES (1) ES2111086T3 (es)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5801175A (en) 1995-04-07 1998-09-01 Schering Corporation Tricyclic compounds useful for inhibition of G-protein function and for treatment of proliferative diseases
IL117798A (en) * 1995-04-07 2001-11-25 Schering Plough Corp Tricyclic compounds useful for inhibiting the function of protein - G and for the treatment of malignant diseases, and pharmaceutical preparations containing them
JP3182685B2 (ja) 1995-09-01 2001-07-03 北陸製薬株式会社 水和物結晶及びその製造方法
AU6754296A (en) * 1995-09-01 1997-03-27 Hokuriku Seiyaku Co. Ltd Crystal of hydrate and process for preparation thereof
JP3723927B2 (ja) * 2000-07-11 2005-12-07 日本ライナー株式会社 エポキシ樹脂を短時間で硬化する方法及び、該硬化方法によって得られたエポキシ樹脂硬化物による電磁波吸収方法
US7355042B2 (en) * 2001-10-16 2008-04-08 Hypnion, Inc. Treatment of CNS disorders using CNS target modulators
AU2004230380A1 (en) * 2003-04-15 2004-10-28 Fujiyakuhin Co., Ltd. Benzoxepino-11-piperidylidene compounds and process for production thereof
US7617820B2 (en) * 2004-06-15 2009-11-17 Smart Parts, Inc. Pneumatic paintball gun

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4826853A (en) * 1986-10-31 1989-05-02 Schering Corporation 6,11-Dihydro-11-(N-substituted-4-piperidylidene)-5H-benzo(5,6)cyclohepta(1,2-B)pyridines and compositions and methods of use
NZ228888A (en) * 1988-04-28 1991-12-23 Schering Corp Derivatives of piperidine, piperidylidene and piperazine and pharmaceutical compositions
IE68935B1 (en) * 1990-06-22 1996-07-24 Schering Corp Bis-benzo or benzopyrido cyclohepta piperidene piperidylidene and piperazine compounds compositions and methods of use
JPH06508129A (ja) * 1991-05-23 1994-09-14 シェリング・コーポレーション 新規のベンゾピリドピペリジリデン化合物、組成物、製造法および使用法
AU2392392A (en) * 1991-07-23 1993-02-23 Schering Corporation Novel benzopyrido piperylidene compounds, compositions, methods of manufacture and methods of use

Also Published As

Publication number Publication date
KR960017669A (ko) 1996-06-17
EP0556813A1 (en) 1993-08-25
EP0556813B1 (en) 1997-11-26
AU3309793A (en) 1993-08-26
DK0556813T3 (da) 1998-08-10
US5334594A (en) 1994-08-02
AU655869B2 (en) 1995-01-12
JP2974529B2 (ja) 1999-11-10
CA2089207C (en) 1997-04-29
KR0140504B1 (ko) 1998-06-01
JPH06192263A (ja) 1994-07-12
ATE160566T1 (de) 1997-12-15
DE69315363T2 (de) 1998-06-25
DE69315363D1 (de) 1998-01-08
CA2089207A1 (en) 1993-08-21

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