ES2094524T3 - Ensayo para homocisteina. - Google Patents

Ensayo para homocisteina.

Info

Publication number
ES2094524T3
ES2094524T3 ES93902437T ES93902437T ES2094524T3 ES 2094524 T3 ES2094524 T3 ES 2094524T3 ES 93902437 T ES93902437 T ES 93902437T ES 93902437 T ES93902437 T ES 93902437T ES 2094524 T3 ES2094524 T3 ES 2094524T3
Authority
ES
Spain
Prior art keywords
enzyme
homocisteine
homocistein
distinct
sample
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES93902437T
Other languages
English (en)
Inventor
Erling Sundrehagen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Axis Biochemicals AS
Original Assignee
Axis Biochemicals AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27266081&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2094524(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from NO920282A external-priority patent/NO920282D0/no
Priority claimed from GB929204922A external-priority patent/GB9204922D0/en
Application filed by Axis Biochemicals AS filed Critical Axis Biochemicals AS
Application granted granted Critical
Publication of ES2094524T3 publication Critical patent/ES2094524T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/48—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving transferase
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02—Acyclic radicals, not substituted by cyclic structures
    • C07H15/14—Acyclic radicals, not substituted by cyclic structures attached to a sulfur, selenium or tellurium atom of a saccharide radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/26—Acyclic or carbocyclic radicals, substituted by hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
    • G01N33/542—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with steric inhibition or signal modification, e.g. fluorescent quenching
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/573—Immunoassay; Biospecific binding assay; Materials therefor for enzymes or isoenzymes
    • G01N33/5735—Immunoassay; Biospecific binding assay; Materials therefor for enzymes or isoenzymes co-enzymes or co-factors, e.g. NAD, ATP
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6806—Determination of free amino acids
    • G01N33/6812—Assays for specific amino acids
    • G01N33/6815—Assays for specific amino acids containing sulfur, e.g. cysteine, cystine, methionine, homocysteine

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Steroid Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Saccharide Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)

Abstract

HAY PROVISTO UN METODO PARA ENSAYAR LA HOMOCISTEINA EN UNA MUESTRA, POR EJEMPLO SANGRE, PLASMA U ORINA, QUE COMPRENDE LOS PASOS DE CONTACTAR DICHA MUESTRA CON UNA ENZIMA QUE CONVIERTE LA HOMOCISTEINA Y AL MENOS UN SUSTRATO PARA OTRA ENZIMA DISTINTA QUE LA HOMOCISTEINA, Y SIN SEPARACION CROMATOGRAFICA QUE EVALUE UN ANALITO NO MARCADO SELECCIONADO DE UN COSUSTRATO DE HOMOCISTEINA Y LOS PRODUCTOS DE LA CONVERSION DE LA HOMOCISTEINA DE LA CONVERSION ENZIMICA DE LA HOMOCISTEINA POR DICHA ENZIMA.
ES93902437T 1992-01-22 1993-01-22 Ensayo para homocisteina. Expired - Lifetime ES2094524T3 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
NO920282A NO920282D0 (no) 1992-01-22 1992-01-22 Fremgangsmaate ved proeving av cystein
US83311892A 1992-02-10 1992-02-10
GB929204922A GB9204922D0 (en) 1992-03-06 1992-03-06 Assay

Publications (1)

Publication Number Publication Date
ES2094524T3 true ES2094524T3 (es) 1997-01-16

Family

ID=27266081

Family Applications (2)

Application Number Title Priority Date Filing Date
ES93902437T Expired - Lifetime ES2094524T3 (es) 1992-01-22 1993-01-22 Ensayo para homocisteina.
ES96200534T Expired - Lifetime ES2196116T5 (es) 1992-01-22 1993-01-22 Ensayo de homocisteína

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES96200534T Expired - Lifetime ES2196116T5 (es) 1992-01-22 1993-01-22 Ensayo de homocisteína

Country Status (18)

Country Link
EP (2) EP0726322B2 (es)
JP (1) JP2870704B2 (es)
AT (2) ATE142271T1 (es)
AU (1) AU676480B2 (es)
BR (1) BR9305780A (es)
CA (1) CA2128512C (es)
CZ (1) CZ287334B6 (es)
DE (2) DE69332891T3 (es)
DK (2) DK0623174T3 (es)
ES (2) ES2094524T3 (es)
FI (1) FI106728B (es)
GR (1) GR3021365T3 (es)
HU (1) HU219607B (es)
NO (1) NO314946B1 (es)
PT (1) PT726322E (es)
RU (1) RU2121001C1 (es)
SK (1) SK281517B6 (es)
WO (1) WO1993015220A1 (es)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5478729A (en) 1994-04-28 1995-12-26 Syntex (U.S.A.) Inc. Immunoassay for homocysteine
GB9617683D0 (en) 1996-08-23 1996-10-02 Univ Glasgow Homocysteine desulphurase
DE19713088C1 (de) 1997-03-27 1998-11-26 Reiner Dr Probst Verfahren und Blutabnahmegefäß zur Aufbereitung von Blutproben für die Homocystein- und/oder Folatbestimmung
US6020206A (en) * 1997-06-23 2000-02-01 Nexstar Pharmaceuticals, Inc. Homocysteine assay
US5985540A (en) * 1997-07-24 1999-11-16 Anticancer, Inc. High specificity homocysteine assays for biological samples
US6066467A (en) * 1997-07-24 2000-05-23 Anticancer, Inc. High specificity homocysteine assays for biological samples
US6468762B1 (en) 1997-07-24 2002-10-22 Anticancer, Inc. High specificity homocysteinases
US6140102A (en) * 1997-07-24 2000-10-31 Anticancer, Inc. High specificity homocysteinases and genes therefor
WO2000000821A1 (en) 1998-06-29 2000-01-06 Ullman Edwin F Assay for homocysteine
GB9900159D0 (en) * 1999-01-05 1999-02-24 Axis Biochemicals Asa Assay
WO2000040746A1 (en) * 1999-01-08 2000-07-13 Medical Analysis Systems, Inc. Compositions and methods for stabilizing thiol-containing biomolecules
ATE380253T1 (de) 1999-02-01 2007-12-15 Anticancer Inc Homogene enzymatische bestimmungsmethode für vitamin b6
US6376210B1 (en) 1999-07-06 2002-04-23 General Atomics Methods and compositions for assaying analytes
CA2377665A1 (en) * 1999-07-06 2001-01-11 General Atomics Methods and compositions for assaying analytes
US7192729B2 (en) 1999-07-06 2007-03-20 General Atomics Methods for assaying homocysteine
US6635438B2 (en) * 1999-11-02 2003-10-21 Catch, Inc. Enzymatic cycling assays for homocysteine and cystathionine
US6610504B1 (en) 2000-04-10 2003-08-26 General Atomics Methods of determining SAM-dependent methyltransferase activity using a mutant SAH hydrolase
GB0008784D0 (en) 2000-04-10 2000-05-31 Axis Shield Plc Assay
DE60131281T2 (de) 2000-06-30 2008-08-28 Alfresa Pharma Corp. Verfahren zum messen von gesamt-homocystein
CA2514877A1 (en) * 2003-01-30 2004-08-12 Bellbrook Labs, Llc Assay method for group transfer reactions
JP2006149203A (ja) * 2003-02-19 2006-06-15 Alfresa Pharma Corp ホモシステインの測定方法
US8476034B2 (en) 2003-07-10 2013-07-02 General Atomics Methods and compositions for assaying homocysteine
US7097968B2 (en) * 2003-07-10 2006-08-29 General Atomics Methods and compositions for assaying homocysteine
RU2268471C2 (ru) * 2004-03-30 2006-01-20 Михаил Борисович Раев Способ определения иммунореактивных соединений
US7384760B2 (en) 2004-04-30 2008-06-10 General Atomics Methods for assaying inhibitors of S-adenosylhomocysteine (SAH) hydrolase and S-adenosylmethionine (SAM)-dependent methyltransferase
GB0503836D0 (en) * 2005-02-24 2005-04-06 Axis Shield Asa Method
JP2007170992A (ja) * 2005-12-22 2007-07-05 Abbott Japan Co Ltd ホモシステインの免疫学的測定方法
JP6056138B2 (ja) * 2010-12-28 2017-01-11 東ソー株式会社 免疫学的測定方法
JP5803104B2 (ja) * 2010-12-28 2015-11-04 東ソー株式会社 安定化されたｓ−アデノシルホモシステイン加水分解酵素調製物
JP5919914B2 (ja) * 2012-03-15 2016-05-18 東ソー株式会社 ホモシステイン測定用前処理試薬

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5811857A (ja) * 1981-07-15 1983-01-22 Yamasa Shoyu Co Ltd アデノシンの定量法
JPS6030679A (ja) * 1983-07-29 1985-02-16 Nippon Zeon Co Ltd Ｓ−アデノシル−ｌ−ホモシステインハイドロラ−ゼの製造法

Also Published As

Publication number Publication date
CA2128512A1 (en) 1993-08-05
HUT67550A (en) 1995-04-28
HU219607B (hu) 2001-05-28
DE69304511D1 (de) 1996-10-10
AU4340893A (en) 1993-09-01
WO1993015220A1 (en) 1993-08-05
CZ176394A3 (en) 1994-12-15
ATE237696T1 (de) 2003-05-15
AU676480B2 (en) 1997-03-13
GR3021365T3 (en) 1997-01-31
DE69332891D1 (de) 2003-05-22
NO942729D0 (no) 1994-07-21
EP0726322B1 (en) 2003-04-16
SK87894A3 (en) 1995-04-12
EP0623174B1 (en) 1996-09-04
FI106728B (fi) 2001-03-30
NO314946B1 (no) 2003-06-16
RU94038061A (ru) 1996-05-27
DE69304511T2 (de) 1997-01-23
EP0623174A1 (en) 1994-11-09
DE69332891T2 (de) 2004-02-19
EP0726322B2 (en) 2011-12-07
JPH08506478A (ja) 1996-07-16
DE69332891T3 (de) 2012-06-14
ATE142271T1 (de) 1996-09-15
NO942729L (no) 1994-09-15
CZ287334B6 (en) 2000-10-11
CA2128512C (en) 1999-12-07
SK281517B6 (sk) 2001-04-09
FI943462L (fi) 1994-09-14
DK0623174T3 (da) 1997-01-13
JP2870704B2 (ja) 1999-03-17
DK0726322T4 (da) 2012-03-19
EP0726322A1 (en) 1996-08-14
ES2196116T5 (es) 2012-04-11
HU9402170D0 (en) 1994-09-28
RU2121001C1 (ru) 1998-10-27
BR9305780A (pt) 1997-02-18
PT726322E (pt) 2003-09-30
ES2196116T3 (es) 2003-12-16
DK0726322T3 (da) 2003-07-28
FI943462A0 (fi) 1994-07-21

Similar Documents

Publication Publication Date Title
ES2094524T3 (es) Ensayo para homocisteina.
CA2127172A1 (en) Analyte Detection Device and Process
DE3370864D1 (en) Device for the detection and quantification of agglutinates
AU9066998A (en) Use of check surfaces for identifying disturbing samples in a detection procedure
ES2157669T3 (es) Un dispositivo para realizar un ensayo, uso de una membrana en la fabricacion de dicho dispositivo, kit que comprende dicho dispositivo, y metodo para la deteccion de un analito usando dicho dispositivo.
AU3538195A (en) Assays and devices for the detection of extrahepatic biliary atresia
CA2198945A1 (en) Apparatus and method for determination of non-hemolyzed levels of occult blood in urine
AU591072B2 (en) Screening test for reverse-transcriptase containing virus
CA2130947A1 (en) Dry Elements, Test Devices, Test Kits and Methods for Chemiluminescent Detection of Analytes Using Peroxidase-Labeled Reagents
CA2204305A1 (en) Apparatus and method for determination of urine color
GB2326943B (en) Detection of fetal red cells in maternal blood
AU2707597A (en) Method of assay
EP0346119A3 (en) Anti-fc assay for detection of antibodies
EP0189925A3 (en) Self-timed immunoassay device
EP1211827A3 (en) Optical signal monitoring system and method of optical signal monitoring
DK72082A (da) Cytoreceptor-proeve
AU3171797A (en) Process to eliminate haemoglobin errors during the determination of albumin
DK0964875T3 (da) Antistof specifikt for 5-hydroxytryptophol eller et konjugat deraf samt immunoassay til bestemmelse af 5-hydroxytryptophol eller konjugater deraf
AU4694096A (en) A-protein as a diagnostic of cancer
ES2066713B1 (es) Metodo para la deteccion de los sistemas abo y rh en hematies.
ES2110910A1 (es) Metodo para la amplificacion de reacciones enzimaticas basado en el acoplamiento a sistemas enzimaticos ciclicos (sec).

Legal Events

Date Code Title Description
FG2A Definitive protection

Ref document number: 623174

Country of ref document: ES