ES2086300T3 - Reactivos de enlace no nucleotidicos para sondas de nucleotidos. - Google Patents

Reactivos de enlace no nucleotidicos para sondas de nucleotidos.

Info

Publication number
ES2086300T3
ES2086300T3 ES88308766T ES88308766T ES2086300T3 ES 2086300 T3 ES2086300 T3 ES 2086300T3 ES 88308766 T ES88308766 T ES 88308766T ES 88308766 T ES88308766 T ES 88308766T ES 2086300 T3 ES2086300 T3 ES 2086300T3
Authority
ES
Spain
Prior art keywords
nucleotide
ligand
nucleotidic
interest
linked
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES88308766T
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English (en)
Inventor
Lyle John Arnold
Mark Alan Reynolds
Ram Saroop Bhatt
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Gen Probe Inc
Original Assignee
Gen Probe Inc
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Publication date
Application filed by Gen Probe Inc filed Critical Gen Probe Inc
Application granted granted Critical
Publication of ES2086300T3 publication Critical patent/ES2086300T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C07H21/02—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with ribosyl as saccharide radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/06—Phosphorus compounds without P—C bonds
    • C07F9/22—Amides of acids of phosphorus
    • C07F9/24—Esteramides
    • C07F9/2404—Esteramides the ester moiety containing a substituent or a structure which is considered as characteristic
    • C07F9/2408—Esteramides the ester moiety containing a substituent or a structure which is considered as characteristic of hydroxyalkyl compounds

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Confectionery (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)

Abstract

REACTIVOS VERSATIL CON UNA UNIDAD MONOMERICA NO NUCLEOTIDICA, QUE TIENE UN LIGANDO Y GRUPOS DE COPULACION PRIMERO Y SEGUNDO UNIDOS A LA UNIDAD MONOMERICA NO NUCLEOTIDICA. EL LIGA DO PUEDE SER UNA PARTE FUNCIONAL, TAL COMO UN MARCADOR O INTERCALADOR, O UN BRAZO DE UNION QUE PUEDE ESTAR UNIDO A LA CITADA PARTE FUNCIONAL. EL REACTIVO PERMITE LA PREPARACION DE POLIMEROS VERSATILES NUCLEOTIDO / NO NUCLEOTIDO, QUE TIENEN UNA SECUENCIA DETERMINADA DE UNIDADES MONOMERICAS NUCLEOTIDICAS Y NO NUCLEOTIDICAS, CADA UNA DE LAS SEGUNDAS DE LAS CUALES LLEVA EL LIGANDO INDICADO. ESTOS POLIMEROS PUEDEN, P.E., SER USADOS COMO SONDAS QUE MUESTRAN SENSIBILIDAD MEJORADA Y/O QUE SON CAPACES DE DETECTAR UN GENERO DE NUCLEOTIDOS CADA ESPECIE DE LOS CUALES TIENE UNA SECUENCIA NUCLEOTIDICA DIANA COMUN, DE INTERES INTERCALADAS ENTRE DIFERENTES SECUENCIAS QUE NO TIENEN INTERES.
ES88308766T 1987-09-21 1988-09-21 Reactivos de enlace no nucleotidicos para sondas de nucleotidos. Expired - Lifetime ES2086300T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US9905087A 1987-09-21 1987-09-21

Publications (1)

Publication Number Publication Date
ES2086300T3 true ES2086300T3 (es) 1996-07-01

Family

ID=22272324

Family Applications (1)

Application Number Title Priority Date Filing Date
ES88308766T Expired - Lifetime ES2086300T3 (es) 1987-09-21 1988-09-21 Reactivos de enlace no nucleotidicos para sondas de nucleotidos.

Country Status (12)

Country Link
EP (1) EP0313219B1 (es)
JP (1) JP3012244B2 (es)
KR (1) KR970005898B1 (es)
AT (1) ATE137755T1 (es)
AU (1) AU630076B2 (es)
CA (1) CA1339303C (es)
DE (2) DE3855275T4 (es)
DK (1) DK244789A (es)
ES (1) ES2086300T3 (es)
FI (1) FI892434A (es)
PT (1) PT88550A (es)
WO (1) WO1989002439A1 (es)

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KR970005898B1 (ko) 1997-04-21
KR890701610A (ko) 1989-12-21
EP0313219A2 (en) 1989-04-26
FI892434A0 (fi) 1989-05-19
EP0313219A3 (en) 1990-05-30
DE3855275T2 (de) 1996-11-14
WO1989002439A1 (en) 1989-03-23
DK244789D0 (da) 1989-05-19
ATE137755T1 (de) 1996-05-15
CA1339303C (en) 1997-08-19
PT88550A (pt) 1989-07-31
FI892434A (fi) 1989-05-19
AU2485688A (en) 1989-04-17
JPH02503146A (ja) 1990-10-04
AU630076B2 (en) 1992-10-22
DK244789A (da) 1989-06-30
JP3012244B2 (ja) 2000-02-21
DE3855275T4 (de) 1997-03-20
EP0313219B1 (en) 1996-05-08
DE3855275D1 (de) 1996-06-13

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