ES2065345T3 - Procedimiento para medir una endotoxina. - Google Patents
Procedimiento para medir una endotoxina.Info
- Publication number
- ES2065345T3 ES2065345T3 ES89103104T ES89103104T ES2065345T3 ES 2065345 T3 ES2065345 T3 ES 2065345T3 ES 89103104 T ES89103104 T ES 89103104T ES 89103104 T ES89103104 T ES 89103104T ES 2065345 T3 ES2065345 T3 ES 2065345T3
- Authority
- ES
- Spain
- Prior art keywords
- endotoxin
- measuring
- procedure
- water
- soluble polysaccharide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/579—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving limulus lysate
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
- C12Q1/37—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving peptidase or proteinase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2337/00—N-linked chromogens for determinations of peptidases and proteinases
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2400/00—Assays, e.g. immunoassays or enzyme assays, involving carbohydrates
- G01N2400/10—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- G01N2400/12—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar
- G01N2400/24—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar beta-D-Glucans, i.e. having beta 1,n (n=3,4,6) linkages between saccharide units, e.g. xanthan
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Urology & Nephrology (AREA)
- Biotechnology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Microbiology (AREA)
- Biomedical Technology (AREA)
- Analytical Chemistry (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Biochemistry (AREA)
- Physics & Mathematics (AREA)
- Hematology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Cell Biology (AREA)
- General Engineering & Computer Science (AREA)
- Biophysics (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
- External Artificial Organs (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
Abstract
LA MEDICION DE LA ENDOTOXINA USANDO LA REACCION DE LISATA HEMOCITA DEL CANGREJO DE HERRADURA CON ENDOTOXINA EN UNA SOLUCION PUEDE SER REALIZADA EN PRESENCIA DE UN POLISACARIDO SOLUBLE EN AGUA CONTENIENDO UN ENLACE (BETA) - 1,3 GLUCOSIDICO Y/O UN DERIVADO POLISACARIDO SLUBLE EN AGUA CONTENIENDO UN ENLACE (BETA) - 1,3 GLUCOSIDICO.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP63045069A JPH0715474B2 (ja) | 1988-02-27 | 1988-02-27 | エンドトキシンの測定法 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2065345T3 true ES2065345T3 (es) | 1995-02-16 |
Family
ID=12709059
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES89103104T Expired - Lifetime ES2065345T3 (es) | 1988-02-27 | 1989-02-22 | Procedimiento para medir una endotoxina. |
Country Status (7)
Country | Link |
---|---|
US (2) | US5179006A (es) |
EP (1) | EP0330991B1 (es) |
JP (1) | JPH0715474B2 (es) |
AT (1) | ATE114051T1 (es) |
CA (1) | CA1339881C (es) |
DE (1) | DE68919245T2 (es) |
ES (1) | ES2065345T3 (es) |
Families Citing this family (30)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH0715474B2 (ja) * | 1988-02-27 | 1995-02-22 | 和光純薬工業株式会社 | エンドトキシンの測定法 |
US5594113A (en) * | 1988-06-23 | 1997-01-14 | Associates Of Cape Cod, Inc. | Endotoxin binding and neutralizing protein and uses thereof |
JP2547264B2 (ja) * | 1988-09-01 | 1996-10-23 | 生化学工業株式会社 | カブトガニ・アメボサイト・ライセートg因子活性化阻害剤 |
CA1328074C (en) * | 1988-09-01 | 1994-03-29 | Shigenori Tanaka | Horseshoe crab amebocyte lysate factor g inhibitor |
KR0141685B1 (ko) * | 1988-09-01 | 1998-07-01 | 야마따니 와따루 | 참게 아메보사이트 라이세이트 g 인자 활성화 저해제 |
JP2944721B2 (ja) * | 1990-08-22 | 1999-09-06 | 生化学工業株式会社 | エンドトキシンの測定剤 |
DE69129365T2 (de) * | 1990-08-22 | 1998-10-08 | Seikagaku Kogyo K K Seikagaku | Testagens für endotoxin |
US5681710A (en) * | 1991-03-14 | 1997-10-28 | Seikagaku Kogyo Kabushiki Kaisha | Reagent for determining (1→3)-β-D-glucan |
CA2112776C (en) * | 1993-01-21 | 2002-11-12 | Masakazu Tsuchiya | Process for inhibiting activity of endotoxin |
JP3242733B2 (ja) * | 1993-02-26 | 2001-12-25 | 生化学工業株式会社 | エンドトキシン特異的測定剤 |
CN1063489C (zh) * | 1993-06-29 | 2001-03-21 | 生化学工业株式会社 | 新多肽及编码该多肽的dna |
JP3429036B2 (ja) * | 1993-09-30 | 2003-07-22 | 生化学工業株式会社 | エンドトキシンの特異的測定剤 |
SG107124A1 (en) * | 1994-08-19 | 2004-11-29 | Univ Singapore | Expression of carcinoscorpius rotundicauda factor c in eukaryotes |
US5637474A (en) * | 1994-10-31 | 1997-06-10 | Wako Pure Chemical Industries, Ltd. | Process for measuring amount of endotoxin or (1→3)-β-D-glucan by kinetic turbidimetric method |
EP0837330B1 (en) | 1996-10-21 | 2005-08-24 | Seikagaku Corporation | Method for measuring Endotoxin |
US6270982B1 (en) | 1997-10-09 | 2001-08-07 | Charles River Laboratories | Methods and compositions for the detection of bacterial endotoxins |
EP0924220A3 (en) | 1997-12-16 | 2000-04-26 | Wako Pure Chemical Industries, Ltd. | Inhibitor of the activation of beta-glucan recognition protein |
US5998389A (en) * | 1998-05-20 | 1999-12-07 | Biowhitaker Technologies | Endotoxin-specific assay |
CN1081193C (zh) * | 1998-07-15 | 2002-03-20 | 王利亚 | 羧甲基茯苓聚糖的合成方法 |
US7329538B2 (en) | 2003-03-17 | 2008-02-12 | Charles River Laboratories, Inc. | Methods and compositions for the detection of microbial contaminants |
US20050026239A1 (en) * | 2003-04-18 | 2005-02-03 | Associates Of Cape Cod, Inc. | Kit for detecting endotoxin in aqueous solutions |
US20050048655A1 (en) * | 2003-04-18 | 2005-03-03 | Novitsky Thomas J. | Kit for detecting endotoxin |
JP2008522640A (ja) * | 2004-12-02 | 2008-07-03 | チャールズ リバー ラボラトリーズ, インコーポレイテッド | グラム陽性菌夾雑物の検出および/または定量化のための方法ならびに組成物 |
DE602006004553D1 (de) * | 2005-01-13 | 2009-02-12 | Charles River Lab Inc | Verfahren zur klassifizierung von mikroben in einer biologischen probe |
US20110065911A1 (en) * | 2008-02-19 | 2011-03-17 | Novogen Research Pty Ltd | Method for producing a bioactive glucan product substantially free of endotoxin contamination |
EP2252636A4 (en) * | 2008-03-11 | 2013-10-02 | Future Fibre Tech Pty Ltd | MODUSMETRIC FIBER SENSOR |
WO2009137244A1 (en) * | 2008-04-15 | 2009-11-12 | Charles River Laboratories, Inc. | Cartridge and method for sample analysis |
CU24073B1 (es) | 2011-12-27 | 2015-01-29 | Ct De Investigación Y Desarrollo De Medicamentos Cidem | COMPOSICIÓN A PARTIR DE EXTRACTO DE HEMOCITOS DE LANGOSTA PARA LA DETECCIÓN DE LIPOPOLISACÁRIDOS, PEPTIDOGLICANOS Y 1,3-ß-D-GLUCANOS |
CN102898533A (zh) * | 2012-10-08 | 2013-01-30 | 湖北省宏源药业有限公司 | 一种羧甲基茯苓多糖的制备方法 |
CN109030486A (zh) * | 2018-09-28 | 2018-12-18 | 润方(北京)生物医药研究院有限公司 | 一种血红蛋白样品的细菌内毒素检测方法 |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4038029A (en) * | 1976-01-20 | 1977-07-26 | Worthington Biochemical Corporation | Limulus lysate turbidity test for pyrogens |
JPS5813516A (ja) * | 1981-07-16 | 1983-01-26 | Seikagaku Kogyo Co Ltd | エンドトキシン特異性のカブトガニ・アメボサイト・ライゼート及びその製造方法 |
SE431228B (sv) * | 1981-12-17 | 1984-01-23 | Kenneth Soderhell | Sett att bestemma bakteriella endotoxin medelst profenoloxidashaltigt blodkroppslysat fran kreftdjur eller insekter och reagens herfor |
JPS5928474A (ja) * | 1982-08-05 | 1984-02-15 | Seikagaku Kogyo Co Ltd | カブトガニのアメボサイト・ライゼ−ト中に存在する凝固系阻害因子の採取法 |
JPS5927828A (ja) * | 1982-08-05 | 1984-02-14 | Seikagaku Kogyo Co Ltd | アメボサイト・ライゼートの調製方法 |
ATE92630T1 (de) * | 1984-06-27 | 1993-08-15 | Wako Pure Chem Ind Ltd | Geraet zur messung von endotoxin. |
JPS6272620A (ja) * | 1985-09-25 | 1987-04-03 | Res Dev Corp Of Japan | 播種性血管内凝固症候群予防・治療剤 |
JPH0715474B2 (ja) * | 1988-02-27 | 1995-02-22 | 和光純薬工業株式会社 | エンドトキシンの測定法 |
JPH0711523B2 (ja) * | 1988-03-16 | 1995-02-08 | 和光純薬工業株式会社 | 試薬の調製方法 |
CA1328074C (en) * | 1988-09-01 | 1994-03-29 | Shigenori Tanaka | Horseshoe crab amebocyte lysate factor g inhibitor |
JPH02216462A (ja) * | 1989-02-17 | 1990-08-29 | Taiyo Fishery Co Ltd | エンドトキシンに対する特異性の高いアメボサイト・ライセート |
JPH02221863A (ja) * | 1989-02-22 | 1990-09-04 | Taiyo Fishery Co Ltd | エンドトキシンに対する特異性の高いアメボサイト・ライセート |
-
1988
- 1988-02-27 JP JP63045069A patent/JPH0715474B2/ja not_active Expired - Fee Related
-
1989
- 1989-02-20 CA CA000591485A patent/CA1339881C/en not_active Expired - Lifetime
- 1989-02-22 ES ES89103104T patent/ES2065345T3/es not_active Expired - Lifetime
- 1989-02-22 EP EP89103104A patent/EP0330991B1/en not_active Expired - Lifetime
- 1989-02-22 AT AT89103104T patent/ATE114051T1/de not_active IP Right Cessation
- 1989-02-22 DE DE68919245T patent/DE68919245T2/de not_active Expired - Lifetime
- 1989-02-23 US US07/313,829 patent/US5179006A/en not_active Expired - Lifetime
-
1992
- 1992-12-07 US US07/986,300 patent/US5318893A/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
JPH0715474B2 (ja) | 1995-02-22 |
ATE114051T1 (de) | 1994-11-15 |
US5318893A (en) | 1994-06-07 |
JPH01219562A (ja) | 1989-09-01 |
DE68919245T2 (de) | 1995-05-18 |
EP0330991B1 (en) | 1994-11-09 |
CA1339881C (en) | 1998-05-26 |
EP0330991A2 (en) | 1989-09-06 |
US5179006A (en) | 1993-01-12 |
EP0330991A3 (en) | 1991-06-19 |
DE68919245D1 (de) | 1994-12-15 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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