ES2063296T3 - Procedimiento para fabricar comprimidos que contienen naproxeno o naproxeno sodico secado por aspersion. - Google Patents
Procedimiento para fabricar comprimidos que contienen naproxeno o naproxeno sodico secado por aspersion.Info
- Publication number
- ES2063296T3 ES2063296T3 ES90314164T ES90314164T ES2063296T3 ES 2063296 T3 ES2063296 T3 ES 2063296T3 ES 90314164 T ES90314164 T ES 90314164T ES 90314164 T ES90314164 T ES 90314164T ES 2063296 T3 ES2063296 T3 ES 2063296T3
- Authority
- ES
- Spain
- Prior art keywords
- tablets
- naproxeno
- spray
- drug
- powder compositions
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pain & Pain Management (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Rheumatology (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
SE DESCRIBE LA PREPARACION DE COMPOSICIONES FARMACEUTICAS EN POLVO QUE SE PUEDAN COMPRIMIR DIRECTAMENTE EN TABLETAS. EL PROCESO DESCRITO INCLUYE EL SOMETER UNA SUSPENSION O DISOLUCION ACUOSA DE UN MEDICAMENTO ACTIVO FARMACEUTICAMENTE, ESPECIFICAMENTE NAPROXEN O NAPROXEN DE SODIO (QUE EN SUSPENSION PUEDE OBTENERSE DIRECTAMENTE SIN SECAR A PARTIR DE LA SINTESIS DEL MEDICAMENTO), SOLO O MEZCLADO CON UNA MEZCLA ACUOSA DE MATERIALES EXCIPIENTES, A UNA FORMA CONTROLADA DE SECADO POR PULVERIZACION PARA PRODUCIR UN POLVO SECO CON PARTICULAS DE TAMAÑO UNIFORME EN LA QUE EL MEDICAMENTO SE DISPERSA UNIFORMEMENTE Y SE CUBRE CON LOS EXCIPIENTES. EL POLVO PUEDE COMBINARSE FACILMENTE CON MATERIALES EXCIPIENTES SECOS ADICIONALES Y FORMARSE EN TABLETAS. EL PROCESO FACILITA AHORROS SUSTANCIALES EN LA FABRICACION DE LAS TABLETAS. LOS COMPUESTOS EN POLVO SECO POR PULVERIZACION SON ALTAMENTE COMPRIMIBLES. UTILIZANDO ESTOS COMPUESTOS EN POLVO SECO POR PULVERIZACION, LAS TABLETAS FORMADAS SE DISUELVEN FACILMENTEY TAMBIEN SON ESTABLES EN CONDICIONES NORMALES DE ALMACENAMIENTO Y CONDICIONES SEVERAS DE TEMPERATURA Y HUMEDAD RELATIVA.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US45510989A | 1989-12-22 | 1989-12-22 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2063296T3 true ES2063296T3 (es) | 1995-01-01 |
Family
ID=23807439
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES90314164T Expired - Lifetime ES2063296T3 (es) | 1989-12-22 | 1990-12-21 | Procedimiento para fabricar comprimidos que contienen naproxeno o naproxeno sodico secado por aspersion. |
Country Status (16)
Country | Link |
---|---|
EP (1) | EP0436373B1 (es) |
JP (1) | JPH05320045A (es) |
KR (1) | KR910011241A (es) |
AT (1) | ATE110267T1 (es) |
AU (1) | AU640725B2 (es) |
CA (1) | CA2032956A1 (es) |
DE (1) | DE69011836T2 (es) |
ES (1) | ES2063296T3 (es) |
FI (1) | FI906372A (es) |
HU (1) | HUT59594A (es) |
IE (1) | IE904666A1 (es) |
IL (1) | IL96749A0 (es) |
NO (1) | NO905557L (es) |
NZ (1) | NZ236631A (es) |
PT (1) | PT96229B (es) |
ZA (1) | ZA9010353B (es) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DK0636023T3 (da) * | 1992-04-15 | 1999-12-06 | Alteon Inc | Fremgangsmåde til spraytørring af aminoguanidin |
WO1998024410A2 (en) * | 1996-12-03 | 1998-06-11 | Schering-Plough Kabushiki Kaisha | Controlled release matrix tablet and method for its preparation |
ES2301670T3 (es) * | 2001-07-30 | 2008-07-01 | Dsm Ip Assets B.V. | Composicion que comprende epigalocatequin galato. |
PT1469833T (pt) | 2002-02-01 | 2021-07-13 | Bend Res Inc | Método para produzir dispersões de fármaco amorfo sólido seco por pulverização homogéneas utilizando aparelho de secagem por pulverização modificado |
US7704528B2 (en) * | 2003-05-05 | 2010-04-27 | Isp Investments Inc. | Binder composition and method for processing poorly compressible drugs into tablets of predetermined hardness and friability |
CL2004001884A1 (es) | 2003-08-04 | 2005-06-03 | Pfizer Prod Inc | Procedimiento de secado por pulverizacion para la formacion de dispersiones solidas amorfas de un farmaco y polimeros. |
UY28583A1 (es) * | 2003-10-30 | 2005-05-31 | Roche Consumer Health Ag | Forma de presentación del naproxeno sodico |
JP2008222567A (ja) * | 2007-03-08 | 2008-09-25 | Iwate Univ | 微粒子の製造方法 |
TW201113266A (en) * | 2009-09-02 | 2011-04-16 | Ziopharm Oncology Inc | Pharmaceutical formulations for indibulin |
IE20100799A1 (en) * | 2010-12-22 | 2012-08-01 | Eurand Pharmaceuticals Ltd | Pharmaceutical composites of poorly water soluble drugs and polymers |
CN107847476A (zh) * | 2015-07-13 | 2018-03-27 | 协和发酵生化株式会社 | 含高浓度精氨酸的片剂 |
JP6619644B2 (ja) * | 2015-12-22 | 2019-12-11 | アサヒグループ食品株式会社 | 錠剤の製造方法、及び錠剤原料用顆粒の製造方法 |
JP7163015B2 (ja) * | 2016-10-31 | 2022-10-31 | エスエス製薬株式会社 | 経口固形組成物 |
KR20220054349A (ko) * | 2019-08-26 | 2022-05-02 | 디에스엠 아이피 어셋츠 비.브이. | 나프록센 및 비타민 b12를 포함하는 고체 경구 투여 형태 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4744987A (en) * | 1985-03-08 | 1988-05-17 | Fmc Corporation | Coprocessed microcrystalline cellulose and calcium carbonate composition and its preparation |
US4753801A (en) * | 1985-10-25 | 1988-06-28 | Eli Lilly And Company | Sustained release tablets |
IE61676B1 (en) * | 1987-07-08 | 1994-11-30 | American Home Prod | Spray dried ibuprofen composition |
IT1226549B (it) * | 1988-07-12 | 1991-01-24 | Resa Farma | Composizioni farmaceutiche ad attivita' analgesica ed antiinfiammatoria per uso orale, dotate di ottima palatabilita' ed esenti da effetti irritanti sulle mucose. |
-
1990
- 1990-12-18 PT PT96229A patent/PT96229B/pt not_active IP Right Cessation
- 1990-12-21 DE DE69011836T patent/DE69011836T2/de not_active Expired - Fee Related
- 1990-12-21 KR KR1019900021295A patent/KR910011241A/ko not_active Application Discontinuation
- 1990-12-21 ZA ZA9010353A patent/ZA9010353B/xx unknown
- 1990-12-21 IL IL96749A patent/IL96749A0/xx unknown
- 1990-12-21 HU HU908395A patent/HUT59594A/hu unknown
- 1990-12-21 NZ NZ236631A patent/NZ236631A/xx unknown
- 1990-12-21 CA CA002032956A patent/CA2032956A1/en not_active Abandoned
- 1990-12-21 IE IE466690A patent/IE904666A1/en unknown
- 1990-12-21 EP EP90314164A patent/EP0436373B1/en not_active Expired - Lifetime
- 1990-12-21 AU AU68375/90A patent/AU640725B2/en not_active Ceased
- 1990-12-21 NO NO90905557A patent/NO905557L/no unknown
- 1990-12-21 FI FI906372A patent/FI906372A/fi not_active IP Right Cessation
- 1990-12-21 ES ES90314164T patent/ES2063296T3/es not_active Expired - Lifetime
- 1990-12-21 AT AT90314164T patent/ATE110267T1/de not_active IP Right Cessation
- 1990-12-25 JP JP2419117A patent/JPH05320045A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
PT96229A (pt) | 1991-09-30 |
HUT59594A (en) | 1992-06-29 |
DE69011836T2 (de) | 1995-03-09 |
HU908395D0 (en) | 1991-07-29 |
PT96229B (pt) | 1998-06-30 |
FI906372A0 (fi) | 1990-12-21 |
NO905557L (no) | 1991-06-24 |
IE904666A1 (en) | 1991-07-17 |
IL96749A0 (en) | 1991-09-16 |
DE69011836D1 (de) | 1994-09-29 |
EP0436373A1 (en) | 1991-07-10 |
NO905557D0 (no) | 1990-12-21 |
JPH05320045A (ja) | 1993-12-03 |
ZA9010353B (en) | 1992-08-26 |
FI906372A (fi) | 1991-06-23 |
AU6837590A (en) | 1991-06-27 |
CA2032956A1 (en) | 1991-06-23 |
KR910011241A (ko) | 1991-08-07 |
ATE110267T1 (de) | 1994-09-15 |
EP0436373B1 (en) | 1994-08-24 |
NZ236631A (en) | 1993-03-26 |
AU640725B2 (en) | 1993-09-02 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ES2063296T3 (es) | Procedimiento para fabricar comprimidos que contienen naproxeno o naproxeno sodico secado por aspersion. | |
KR880004805A (ko) | 분무건조된 아세트아미노펜 | |
ATE66141T1 (de) | Pharmazeutische zusammensetzung. | |
BR9206996A (pt) | Composição adequada para preparar esferóides por esferoidização processo para produzir um material em partículas processo para produzir uma forma de dosagem de sólido esferoidizado em partículas e forma de dosagem sólida | |
ATE125155T1 (de) | Niedrigdosierte getrocknete pharmazeutische präparate. | |
AR011080A1 (es) | Composicion en polvo seco, proceso para su preparacion y uso de dicha composicion para la fabricacion del medicamento | |
KR910014120A (ko) | 피모벤단의 경구용 약제학적 제제 | |
ES2040733T3 (es) | Medicamentos que contienen clodronato y procedimiento para su preparacion. | |
BR9913782A (pt) | Processo de preparação de uma formualação galênica que compreende fenofibrato como princìpio ativo, formulação galênica, medicamento e utilizações de um meio lìquido e de partìculas de fenofibrato | |
RU2002123182A (ru) | Содержащая ибупрофен композиция | |
ATE17650T1 (de) | Trockenpulverisierte n-acetyl-p-aminophenolzusammensetzungenund verfahren zu deren herstellung. | |
JPS5474855A (en) | Preparation of finely divided soluble cellulose derivative | |
US5534551A (en) | Aminoguanidine spray drying process | |
JPS557236A (en) | Preparation of powdery sodium acetate (anhydrous) | |
CZ286197B6 (cs) | Příprava tablet kyseliny fusidové | |
MY101266A (en) | Pharmaceutical formulations | |
BR1100487A (pt) | Processo para a preparação de pelotas e medicamentos para a administração oral | |
RU98115790A (ru) | Способ получения таблеток ранитидина | |
JPS56156214A (en) | Preparation of tableting enteric microcapsule | |
KR900000075A (ko) | 장용성 과립제의 제조방법 | |
RU97106462A (ru) | Способ получения таблетированной формы препарата |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
Ref document number: 436373 Country of ref document: ES |