ATE110267T1 - Verfahren zur hestellung von tabletten, die sprühgetrocknetes naproxen oder naproxen natriumsalz enthalten. - Google Patents

Verfahren zur hestellung von tabletten, die sprühgetrocknetes naproxen oder naproxen natriumsalz enthalten.

Info

Publication number
ATE110267T1
ATE110267T1 AT90314164T AT90314164T ATE110267T1 AT E110267 T1 ATE110267 T1 AT E110267T1 AT 90314164 T AT90314164 T AT 90314164T AT 90314164 T AT90314164 T AT 90314164T AT E110267 T1 ATE110267 T1 AT E110267T1
Authority
AT
Austria
Prior art keywords
tablets
naproxen
spray dried
manufacture
drug
Prior art date
Application number
AT90314164T
Other languages
English (en)
Inventor
Roy Kuramoto
Randal Owen Pendleton
Zadauddin Tanwir Chowhan
Hafez Hafezzadeh
Original Assignee
Syntex Pharma Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Syntex Pharma Int filed Critical Syntex Pharma Int
Application granted granted Critical
Publication of ATE110267T1 publication Critical patent/ATE110267T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Rheumatology (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT90314164T 1989-12-22 1990-12-21 Verfahren zur hestellung von tabletten, die sprühgetrocknetes naproxen oder naproxen natriumsalz enthalten. ATE110267T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US45510989A 1989-12-22 1989-12-22

Publications (1)

Publication Number Publication Date
ATE110267T1 true ATE110267T1 (de) 1994-09-15

Family

ID=23807439

Family Applications (1)

Application Number Title Priority Date Filing Date
AT90314164T ATE110267T1 (de) 1989-12-22 1990-12-21 Verfahren zur hestellung von tabletten, die sprühgetrocknetes naproxen oder naproxen natriumsalz enthalten.

Country Status (16)

Country Link
EP (1) EP0436373B1 (de)
JP (1) JPH05320045A (de)
KR (1) KR910011241A (de)
AT (1) ATE110267T1 (de)
AU (1) AU640725B2 (de)
CA (1) CA2032956A1 (de)
DE (1) DE69011836T2 (de)
ES (1) ES2063296T3 (de)
FI (1) FI906372A (de)
HU (1) HUT59594A (de)
IE (1) IE904666A1 (de)
IL (1) IL96749A0 (de)
NO (1) NO905557L (de)
NZ (1) NZ236631A (de)
PT (1) PT96229B (de)
ZA (1) ZA9010353B (de)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK0636023T3 (da) * 1992-04-15 1999-12-06 Alteon Inc Fremgangsmåde til spraytørring af aminoguanidin
WO1998024410A2 (en) * 1996-12-03 1998-06-11 Schering-Plough Kabushiki Kaisha Controlled release matrix tablet and method for its preparation
ES2301670T3 (es) * 2001-07-30 2008-07-01 Dsm Ip Assets B.V. Composicion que comprende epigalocatequin galato.
PT1469833T (pt) 2002-02-01 2021-07-13 Bend Res Inc Método para produzir dispersões de fármaco amorfo sólido seco por pulverização homogéneas utilizando aparelho de secagem por pulverização modificado
US7704528B2 (en) * 2003-05-05 2010-04-27 Isp Investments Inc. Binder composition and method for processing poorly compressible drugs into tablets of predetermined hardness and friability
CL2004001884A1 (es) 2003-08-04 2005-06-03 Pfizer Prod Inc Procedimiento de secado por pulverizacion para la formacion de dispersiones solidas amorfas de un farmaco y polimeros.
UY28583A1 (es) * 2003-10-30 2005-05-31 Roche Consumer Health Ag Forma de presentación del naproxeno sodico
JP2008222567A (ja) * 2007-03-08 2008-09-25 Iwate Univ 微粒子の製造方法
TW201113266A (en) * 2009-09-02 2011-04-16 Ziopharm Oncology Inc Pharmaceutical formulations for indibulin
IE20100799A1 (en) * 2010-12-22 2012-08-01 Eurand Pharmaceuticals Ltd Pharmaceutical composites of poorly water soluble drugs and polymers
CN107847476A (zh) * 2015-07-13 2018-03-27 协和发酵生化株式会社 含高浓度精氨酸的片剂
JP6619644B2 (ja) * 2015-12-22 2019-12-11 アサヒグループ食品株式会社 錠剤の製造方法、及び錠剤原料用顆粒の製造方法
JP7163015B2 (ja) * 2016-10-31 2022-10-31 エスエス製薬株式会社 経口固形組成物
KR20220054349A (ko) * 2019-08-26 2022-05-02 디에스엠 아이피 어셋츠 비.브이. 나프록센 및 비타민 b12를 포함하는 고체 경구 투여 형태

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4744987A (en) * 1985-03-08 1988-05-17 Fmc Corporation Coprocessed microcrystalline cellulose and calcium carbonate composition and its preparation
US4753801A (en) * 1985-10-25 1988-06-28 Eli Lilly And Company Sustained release tablets
IE61676B1 (en) * 1987-07-08 1994-11-30 American Home Prod Spray dried ibuprofen composition
IT1226549B (it) * 1988-07-12 1991-01-24 Resa Farma Composizioni farmaceutiche ad attivita' analgesica ed antiinfiammatoria per uso orale, dotate di ottima palatabilita' ed esenti da effetti irritanti sulle mucose.

Also Published As

Publication number Publication date
PT96229A (pt) 1991-09-30
HUT59594A (en) 1992-06-29
DE69011836T2 (de) 1995-03-09
ES2063296T3 (es) 1995-01-01
HU908395D0 (en) 1991-07-29
PT96229B (pt) 1998-06-30
FI906372A0 (fi) 1990-12-21
NO905557L (no) 1991-06-24
IE904666A1 (en) 1991-07-17
IL96749A0 (en) 1991-09-16
DE69011836D1 (de) 1994-09-29
EP0436373A1 (de) 1991-07-10
NO905557D0 (no) 1990-12-21
JPH05320045A (ja) 1993-12-03
ZA9010353B (en) 1992-08-26
FI906372A (fi) 1991-06-23
AU6837590A (en) 1991-06-27
CA2032956A1 (en) 1991-06-23
KR910011241A (ko) 1991-08-07
EP0436373B1 (de) 1994-08-24
NZ236631A (en) 1993-03-26
AU640725B2 (en) 1993-09-02

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RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties