DE69011836D1 - Verfahren zur Hestellung von Tabletten, die sprühgetrocknetes Naproxen oder Naproxen Natriumsalz enthalten. - Google Patents

Verfahren zur Hestellung von Tabletten, die sprühgetrocknetes Naproxen oder Naproxen Natriumsalz enthalten.

Info

Publication number
DE69011836D1
DE69011836D1 DE69011836T DE69011836T DE69011836D1 DE 69011836 D1 DE69011836 D1 DE 69011836D1 DE 69011836 T DE69011836 T DE 69011836T DE 69011836 T DE69011836 T DE 69011836T DE 69011836 D1 DE69011836 D1 DE 69011836D1
Authority
DE
Germany
Prior art keywords
tablets
naproxen
manufacture
drug
powder compositions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69011836T
Other languages
English (en)
Other versions
DE69011836T2 (de
Inventor
Roy Kuramoto
Randal Owen Pendleton
Zadauddin Tanwir Chowhan
Hafez Hafezzadeh
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Syntex Pharmaceuticals International Ltd
Original Assignee
Syntex Pharmaceuticals International Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Syntex Pharmaceuticals International Ltd filed Critical Syntex Pharmaceuticals International Ltd
Publication of DE69011836D1 publication Critical patent/DE69011836D1/de
Application granted granted Critical
Publication of DE69011836T2 publication Critical patent/DE69011836T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
DE69011836T 1989-12-22 1990-12-21 Verfahren zur Hestellung von Tabletten, die sprühgetrocknetes Naproxen oder Naproxen Natriumsalz enthalten. Expired - Fee Related DE69011836T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US45510989A 1989-12-22 1989-12-22

Publications (2)

Publication Number Publication Date
DE69011836D1 true DE69011836D1 (de) 1994-09-29
DE69011836T2 DE69011836T2 (de) 1995-03-09

Family

ID=23807439

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69011836T Expired - Fee Related DE69011836T2 (de) 1989-12-22 1990-12-21 Verfahren zur Hestellung von Tabletten, die sprühgetrocknetes Naproxen oder Naproxen Natriumsalz enthalten.

Country Status (16)

Country Link
EP (1) EP0436373B1 (de)
JP (1) JPH05320045A (de)
KR (1) KR910011241A (de)
AT (1) ATE110267T1 (de)
AU (1) AU640725B2 (de)
CA (1) CA2032956A1 (de)
DE (1) DE69011836T2 (de)
ES (1) ES2063296T3 (de)
FI (1) FI906372A (de)
HU (1) HUT59594A (de)
IE (1) IE904666A1 (de)
IL (1) IL96749A0 (de)
NO (1) NO905557L (de)
NZ (1) NZ236631A (de)
PT (1) PT96229B (de)
ZA (1) ZA9010353B (de)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH07505654A (ja) * 1992-04-15 1995-06-22 マリオン　メレルダウ　インコーポレーテッド アミノグアニジン噴霧乾燥法
WO1998024410A2 (en) * 1996-12-03 1998-06-11 Schering-Plough Kabushiki Kaisha Controlled release matrix tablet and method for its preparation
EP1411986B1 (de) * 2001-07-30 2008-03-12 DSM IP Assets B.V. Zusammensetzung enthaltend epigallocatechin-gallat
CN1309370C (zh) 2002-02-01 2007-04-11 辉瑞产品公司 使用改进的喷雾干燥设备制备均匀喷雾干燥的固体非晶形药物分散体的方法
US7704528B2 (en) * 2003-05-05 2010-04-27 Isp Investments Inc. Binder composition and method for processing poorly compressible drugs into tablets of predetermined hardness and friability
CL2004001884A1 (es) 2003-08-04 2005-06-03 Pfizer Prod Inc Procedimiento de secado por pulverizacion para la formacion de dispersiones solidas amorfas de un farmaco y polimeros.
PE20050445A1 (es) * 2003-10-30 2005-06-18 Bayer Consumer Care Ag Forma de presentacion del naproxeno sodico
JP2008222567A (ja) * 2007-03-08 2008-09-25 Iwate Univ 微粒子の製造方法
TW201113266A (en) * 2009-09-02 2011-04-16 Ziopharm Oncology Inc Pharmaceutical formulations for indibulin
IE20100799A1 (en) * 2010-12-22 2012-08-01 Eurand Pharmaceuticals Ltd Pharmaceutical composites of poorly water soluble drugs and polymers
CN107847476A (zh) * 2015-07-13 2018-03-27 协和发酵生化株式会社 含高浓度精氨酸的片剂
JP6619644B2 (ja) * 2015-12-22 2019-12-11 アサヒグループ食品株式会社 錠剤の製造方法、及び錠剤原料用顆粒の製造方法
JP7163015B2 (ja) * 2016-10-31 2022-10-31 エスエス製薬株式会社 経口固形組成物
KR20220054349A (ko) * 2019-08-26 2022-05-02 디에스엠 아이피 어셋츠 비.브이. 나프록센 및 비타민 b12를 포함하는 고체 경구 투여 형태

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4744987A (en) * 1985-03-08 1988-05-17 Fmc Corporation Coprocessed microcrystalline cellulose and calcium carbonate composition and its preparation
US4753801A (en) * 1985-10-25 1988-06-28 Eli Lilly And Company Sustained release tablets
EP0298666B1 (de) * 1987-07-08 1993-08-11 American Home Products Corporation Sprühgetrocknete Ibuprofen-Zusammensetzungen
IT1226549B (it) * 1988-07-12 1991-01-24 Resa Farma Composizioni farmaceutiche ad attivita' analgesica ed antiinfiammatoria per uso orale, dotate di ottima palatabilita' ed esenti da effetti irritanti sulle mucose.

Also Published As

Publication number Publication date
HUT59594A (en) 1992-06-29
ATE110267T1 (de) 1994-09-15
NZ236631A (en) 1993-03-26
CA2032956A1 (en) 1991-06-23
FI906372A0 (fi) 1990-12-21
ZA9010353B (en) 1992-08-26
PT96229A (pt) 1991-09-30
FI906372A (fi) 1991-06-23
IE904666A1 (en) 1991-07-17
ES2063296T3 (es) 1995-01-01
IL96749A0 (en) 1991-09-16
NO905557L (no) 1991-06-24
NO905557D0 (no) 1990-12-21
HU908395D0 (en) 1991-07-29
EP0436373A1 (de) 1991-07-10
AU640725B2 (en) 1993-09-02
DE69011836T2 (de) 1995-03-09
AU6837590A (en) 1991-06-27
KR910011241A (ko) 1991-08-07
EP0436373B1 (de) 1994-08-24
PT96229B (pt) 1998-06-30
JPH05320045A (ja) 1993-12-03

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8328 Change in the person/name/address of the agent

Free format text: BARZ, P., DIPL.-CHEM. DR.RER.NAT., PAT.-ANW., 80803 MUENCHEN

8339 Ceased/non-payment of the annual fee