ES2058146T3 - Un procedimiento para preparar un compuesto tetrahidro ciclohepta(1,2-c:4,3-c')dipirazoles. - Google Patents

Un procedimiento para preparar un compuesto tetrahidro ciclohepta(1,2-c:4,3-c')dipirazoles.

Info

Publication number
ES2058146T3
ES2058146T3 ES88101181T ES88101181T ES2058146T3 ES 2058146 T3 ES2058146 T3 ES 2058146T3 ES 88101181 T ES88101181 T ES 88101181T ES 88101181 T ES88101181 T ES 88101181T ES 2058146 T3 ES2058146 T3 ES 2058146T3
Authority
ES
Spain
Prior art keywords
dipirazoles
compound
cyclohepta
tetrahydro
preparing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES88101181T
Other languages
English (en)
Inventor
Tourneau Michael E Le
Norton P Peet
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aventis Pharmaceuticals Inc
Original Assignee
Merrell Dow Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Dow Pharmaceuticals Inc filed Critical Merrell Dow Pharmaceuticals Inc
Application granted granted Critical
Publication of ES2058146T3 publication Critical patent/ES2058146T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)

Abstract

LA PRESENTE INVENCION SE DIRIGE A UN GRUPO DE TETRAHIDRO CICLOHEPTA [1,2-C:4,3-C''] DIPIRAZOLES Y BENZO [1,2-C:4,3-C''] DIPIRAZOLES METILADOS UTILES COMO BRONCODILATADORES. LOS COMPUESTOS SE PREPARAN POR REACCION DE UNA HIDRAZINA APROPIADA CON UNA 1,3-DICETONA ADECUADA O CON UN COMPUESTO QUE SEA QUIMICAMENTE EQUIVALENTE A UNA 1,3-DICETONA.
ES88101181T 1987-01-27 1988-01-27 Un procedimiento para preparar un compuesto tetrahidro ciclohepta(1,2-c:4,3-c')dipirazoles. Expired - Lifetime ES2058146T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/007,304 US4734429A (en) 1987-01-27 1987-01-27 Cycloalkane[1,2-c:4,3-c']dipyrazoles and their use as bronchodilators

Publications (1)

Publication Number Publication Date
ES2058146T3 true ES2058146T3 (es) 1994-11-01

Family

ID=21725387

Family Applications (1)

Application Number Title Priority Date Filing Date
ES88101181T Expired - Lifetime ES2058146T3 (es) 1987-01-27 1988-01-27 Un procedimiento para preparar un compuesto tetrahidro ciclohepta(1,2-c:4,3-c')dipirazoles.

Country Status (21)

Country Link
US (1) US4734429A (es)
EP (1) EP0276834B1 (es)
JP (1) JP2571410B2 (es)
KR (1) KR950011738B1 (es)
CN (1) CN88100329A (es)
AR (1) AR242578A1 (es)
AT (1) ATE90098T1 (es)
AU (1) AU594226B2 (es)
CA (1) CA1327586C (es)
DE (1) DE3881406T2 (es)
DK (1) DK35088A (es)
ES (1) ES2058146T3 (es)
FI (1) FI89358C (es)
HU (1) HU197905B (es)
IE (1) IE880193L (es)
IL (1) IL85187A (es)
NO (1) NO166366C (es)
NZ (1) NZ223257A (es)
PH (1) PH24127A (es)
PT (1) PT86624B (es)
ZA (1) ZA88527B (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2003218989A1 (en) * 2002-02-19 2003-09-09 Pharmacia Italia S.P.A. Tricyclic pyrazole derivatives, process for their preparation and their use as antitumor agents
BRPI0514736A (pt) * 2004-08-27 2008-06-24 Esteve Labor Dr inibidores do receptor sigma
EP1634873A1 (en) * 2004-08-27 2006-03-15 Laboratorios Del Dr. Esteve, S.A. Sigma receptor inhibitors
DE102011106849A1 (de) 2010-12-15 2012-06-21 Merck Patent Gmbh Verfahren zur Synthese N-N verknüpfter und um die N-N Bindung rotationsgehinderter bis-N-heterocyclische Carbene und deren Einsatz als Liganden für Metallkomplexe

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3404157A (en) * 1965-02-24 1968-10-01 American Cyanamid Co Substituted pyrroloindazole compounds
US4515948A (en) * 1973-09-12 1985-05-07 Hoffmann-La Roche Inc. 2,4-Diamino-5-(4-amino and 4-dimethylamino-3,5-dimethoxy benzyl)pyrimidines
JPS5615287A (en) * 1979-07-16 1981-02-14 Chugai Pharmaceut Co Ltd Pyrazoloindazole derivative and its preparation
KR880009024A (ko) * 1987-01-27 1988-09-13 게리 디.스트리트 기관지 확장제용 디피라졸

Also Published As

Publication number Publication date
FI880284A (fi) 1988-07-28
FI880284A0 (fi) 1988-01-22
KR950011738B1 (ko) 1995-10-09
NZ223257A (en) 1989-11-28
NO880338L (no) 1988-07-28
NO166366B (no) 1991-04-02
NO166366C (no) 1991-07-10
ATE90098T1 (de) 1993-06-15
FI89358B (fi) 1993-06-15
DE3881406T2 (de) 1993-09-16
HU197905B (en) 1989-06-28
AU1072588A (en) 1988-07-28
PT86624A (pt) 1988-02-01
JP2571410B2 (ja) 1997-01-16
CA1327586C (en) 1994-03-08
EP0276834A1 (en) 1988-08-03
HUT47280A (en) 1989-02-28
PH24127A (en) 1990-03-05
IE880193L (en) 1988-07-27
DK35088D0 (da) 1988-01-26
IL85187A0 (en) 1988-07-31
PT86624B (pt) 1991-12-31
CN88100329A (zh) 1988-09-28
IL85187A (en) 1991-07-18
AU594226B2 (en) 1990-03-01
FI89358C (fi) 1993-09-27
DE3881406D1 (de) 1993-07-08
KR880009023A (ko) 1988-09-13
ZA88527B (en) 1988-09-28
JPS63192774A (ja) 1988-08-10
AR242578A1 (es) 1993-04-30
DK35088A (da) 1988-07-28
EP0276834B1 (en) 1993-06-02
NO880338D0 (no) 1988-01-26
US4734429A (en) 1988-03-29

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