ES2053198T3 - Sistema de suministro de un farmaco de glucano y adyuvante. - Google Patents

Sistema de suministro de un farmaco de glucano y adyuvante.

Info

Publication number
ES2053198T3
ES2053198T3 ES90910219T ES90910219T ES2053198T3 ES 2053198 T3 ES2053198 T3 ES 2053198T3 ES 90910219 T ES90910219 T ES 90910219T ES 90910219 T ES90910219 T ES 90910219T ES 2053198 T3 ES2053198 T3 ES 2053198T3
Authority
ES
Spain
Prior art keywords
glucan
drug
pct
beta
pharmacy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES90910219T
Other languages
English (en)
Inventor
Spiros Jamas
Gary R Ostroff
D Davidson Easson Jr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Alpha Beta Technology Inc
Original Assignee
Alpha Beta Technology Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alpha Beta Technology Inc filed Critical Alpha Beta Technology Inc
Application granted granted Critical
Publication of ES2053198T3 publication Critical patent/ES2053198T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5063—Compounds of unknown constitution, e.g. material from plants or animals
    • A61K9/5068—Cell membranes or bacterial membranes enclosing drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55555—Liposomes; Vesicles, e.g. nanoparticles; Spheres, e.g. nanospheres; Polymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55583—Polysaccharides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/81—Carrier - bound or immobilized peptides or proteins and the preparation thereof, e.g. biological cell or cell fragment as carrier
    • Y10S530/812—Peptides or proteins is immobilized on, or in, an organic carrier
    • Y10S530/815—Carrier is a synthetic polymer
    • Y10S530/817—Entrapped within the carrier, e.g. gel, hollow fibre

Abstract

ESTA INVENCION SE REFIERE A UN VEHICULO (BETA)-GLUCAN PORTADOR DE MEDICAMENTOS QUE POTENCIA NO-ESPECIFICAMENTE LA RESPUESTA INMUNE, Y QUE ES SEGURO PARA EL USO HUMANO. UNA MEDICINA SE INCORPORA A LA MICROPARTICULA DE (BETA)-GLUCAN Y LA COMBINACION ES ADMINISTRADA AL INDIVIDUO. EL VEHICULO (BETA)-GLUCAN PERMITE LA EMISION SOSTENIDA DEL COMPONENTE DE LA MEDICINA MIENTRAS QUE SIMULTANEAMENTE POTENCIA LA EFECTIVIDAD DE LA DROGA AL POTENCIAR LA RESPUESTA INMUNE ENDOGENA DEL INDIVIDUO.
ES90910219T 1989-06-15 1990-06-14 Sistema de suministro de un farmaco de glucano y adyuvante. Expired - Lifetime ES2053198T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/366,490 US5032401A (en) 1989-06-15 1989-06-15 Glucan drug delivery system and adjuvant

Publications (1)

Publication Number Publication Date
ES2053198T3 true ES2053198T3 (es) 1994-07-16

Family

ID=23443232

Family Applications (1)

Application Number Title Priority Date Filing Date
ES90910219T Expired - Lifetime ES2053198T3 (es) 1989-06-15 1990-06-14 Sistema de suministro de un farmaco de glucano y adyuvante.

Country Status (9)

Country Link
US (3) US5032401A (es)
EP (1) EP0476063B1 (es)
JP (1) JPH05503285A (es)
AT (1) ATE106013T1 (es)
AU (1) AU5933190A (es)
CA (1) CA2059275A1 (es)
DE (1) DE69009185T2 (es)
ES (1) ES2053198T3 (es)
WO (1) WO1990015596A1 (es)

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