ES2052296T3 - Derivados de tieno(2,3-d)pirimidina. - Google Patents

Derivados de tieno(2,3-d)pirimidina.

Info

Publication number
ES2052296T3
ES2052296T3 ES91103547T ES91103547T ES2052296T3 ES 2052296 T3 ES2052296 T3 ES 2052296T3 ES 91103547 T ES91103547 T ES 91103547T ES 91103547 T ES91103547 T ES 91103547T ES 2052296 T3 ES2052296 T3 ES 2052296T3
Authority
ES
Spain
Prior art keywords
sub
rest
elevated
mean
hydroxy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES91103547T
Other languages
English (en)
Inventor
Matthias Dr Wiesenfeldt
Karl-Heinz Dr Etzbach
Peter Dr Hofmeister
Christoph Dr Kuenast
Karl-Otto Dr Westphalen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
BASF SE
Original Assignee
BASF SE
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by BASF SE filed Critical BASF SE
Application granted granted Critical
Publication of ES2052296T3 publication Critical patent/ES2052296T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/90—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having two or more relevant hetero rings, condensed among themselves or with a common carbocyclic ring system

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Plant Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Dentistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Pest Control & Pesticides (AREA)
  • Agronomy & Crop Science (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

TIENO [2,3-D] DERIVADOS DE PIRIMIDINA DE LA FORMULA GENERAL I EN LA QUE LOS SUSTITUYENTES TIENEN EL SIGUIENTE SIGNIFICADO; R ELEVADO 1 HIDROGENO, C SUB 1-C SUB 5 ALQUILO, C SUB 1-C SUB 3 CLOROALQUILO, C SUB 3-C SUB 6 CICLOALQUILO, FENILO O BENCILO R (AL CUADRADO) FLUOR, CLORO, BROMO, YODO, HIDROXY, ACIDO, CIANO, TIOCIANATO, MERCAPTO, UN RESTO ORGANICO NO UNIDO SOBRE NITROGENO O UN RESTO NR ELEVADO 5 R ELEVADO 6, DEL QUE R ELEVADO 5 Y R ELEVADO 6 SIGNIFICAN HIDROGENO, AMINO O RESTO ORGANICO INDEPENDIENTES ENTRE ELLOS O CONJUNTAMENTE CON EL ATOMO DE NITROGENO FORMAN UN RESTO HETEROCICLICO CON 3 HASTA 8 CICLOATOMOS, CON LA RESERVA, DE QUE R (AL CUADRADO) NO SIGNIFICA FENOXI-C SUB 2-C SUB 3 ALQUILAMINO, R ELEVADO 3 CLORO, BROMO, HIDROXY O MERCAPTO, CON LA RESERVA, DE QUE R (AL CUADRADO) HIDROXI Y R ELEVADO 3 NO SIGNIFICAN BROMO SIMULTANEAMENTE Y DE QUE NO SIGNIFICA SIMULTANEAMENTE R ELEVADO 3 HIDROXI Y R ELEVADO 4 ALCOXICARBONILO O CARBOXY R ELEVADO 4 HIDROGENO, C SUB 1-C SUB 6 ALQUILO, C SUB 3-C SUB 6 MONO-, DI-, O TRIHALOGENURO DE ALQUILO, FENILO CIANO, FORMILO, HIDROXIIMINOMETILO, CARBOXY, ALCOXICARBONILO, AMINOCARBONILO O UN RESTO DE LA FORMULA CH=X POR LA CUAL X SOBRE RESTO UNIDO DE NITROGENO DE UN AMINO PRIMARIO O SOBRE EL RESTO UNIDO DE CARBONO ES UNA COMBINACION METILOACTIVA, ASI COMO LOS TAUTOMEROS DE ESTE TIENO[2,3-D] DERIVADOS DE PIRAMIDINA Y LAS SALES TOLERADAS DE PLANTAS UTILES DE ESTE DERIVADO Y SUS TAUTOMEROS. LAS COMBINACIONES I ENCUENTRAN UTILIZACION COMO INSECTICIDAS, REGULADORES DE CRECIMIENTO, Y HERBICIDAS
ES91103547T 1990-03-19 1991-03-08 Derivados de tieno(2,3-d)pirimidina. Expired - Lifetime ES2052296T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19904008726 DE4008726A1 (de) 1990-03-19 1990-03-19 Thieno(2,3-d)pyrimidinderivate

Publications (1)

Publication Number Publication Date
ES2052296T3 true ES2052296T3 (es) 1994-07-01

Family

ID=6402524

Family Applications (1)

Application Number Title Priority Date Filing Date
ES91103547T Expired - Lifetime ES2052296T3 (es) 1990-03-19 1991-03-08 Derivados de tieno(2,3-d)pirimidina.

Country Status (6)

Country Link
EP (1) EP0447891B1 (es)
JP (1) JPH04217685A (es)
CA (1) CA2038521A1 (es)
DE (2) DE4008726A1 (es)
DK (1) DK0447891T3 (es)
ES (1) ES2052296T3 (es)

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US5869486A (en) * 1995-02-24 1999-02-09 Ono Pharmaceutical Co., Ltd. Fused pyrimidines and pyriazines as pharmaceutical compounds
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DE19924668A1 (de) * 1999-05-28 2000-11-30 Bayer Ag Substituierte alpha-Phenyl-beta-Ketosulfone
US6503914B1 (en) 2000-10-23 2003-01-07 Board Of Regents, The University Of Texas System Thienopyrimidine-based inhibitors of the Src family
AU2002333524A1 (en) 2001-09-11 2003-03-24 Glaxosmithkline K.K. Furo-and thienopyrimidine derivatives as angiogenesis inhibitors
AU2003246972A1 (en) 2002-08-06 2004-02-23 Astrazeneca Ab Condensed pyridines and pyrimidines with tie2 (tek) activity
JP2004137270A (ja) * 2002-09-26 2004-05-13 Nippon Nohyaku Co Ltd 新規除草剤、その使用方法、新規置換チエノピリミジン誘導体及びその中間体並びにそれらの製造方法
AR044743A1 (es) * 2002-09-26 2005-10-05 Nihon Nohyaku Co Ltd Herbicida, metodo de emplearlo, derivados de tienopirimidina sustituida,compuestos intermediarios, y procedimientos que se utilizan para producirlos,
ES2217956B1 (es) * 2003-01-23 2006-04-01 Almirall Prodesfarma, S.A. Nuevos derivados de 4-aminotieno(2,3-d)pirimidin-6-carbonitrilo.
WO2004089312A2 (en) * 2003-03-31 2004-10-21 Predix Pharmaceuticals Holdings, Inc. New piperidinylamino-thieno[2,3-d] pyrimidine compounds
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US7419978B2 (en) 2003-10-22 2008-09-02 Bristol-Myers Squibb Company Phenyl-aniline substituted bicyclic compounds useful as kinase inhibitors
WO2005080377A1 (ja) * 2004-02-20 2005-09-01 Kirin Beer Kabushiki Kaisha TGFβ阻害活性を有する化合物およびそれを含んでなる医薬組成物
US7488736B2 (en) 2004-05-17 2009-02-10 Epix Delaware, Inc. Thienopyridinone compounds and methods of treatment
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US7531482B2 (en) 2005-10-21 2009-05-12 Dow Agrosciences Llc Thieno-pyrimidine compounds having fungicidal activity
WO2007046809A1 (en) * 2005-10-21 2007-04-26 Dow Agrosciences Llc Thieno-pyrimidine compounds having fungicidal activity
AR059898A1 (es) 2006-03-15 2008-05-07 Janssen Pharmaceutica Nv Derivados de 3-ciano-piridona 1,4-disustituida y su uso como moduladores alostericos de los receptores mglur2
CA2651898A1 (en) 2006-04-07 2007-10-18 Develogen Aktiengesellschaft Thienopyrimidines having mnk1/mnk2 inhibiting activity for pharmaceutical compositions
BRPI0711772B8 (pt) * 2006-05-22 2017-08-01 Basf Se método para combater ou controlar insetos, aracnídeos ou nematódeos; método para proteger colheitas e plantas em crescimento do ataque ou infestação de insetos, aracnídeos ou nematódeos; e método para proteger sementes dos insetos de solo e raízes e rebentos das mudas dos insetos de solo; composto e composição agricultural ou veterinária
EP1889847A1 (en) 2006-07-10 2008-02-20 DeveloGen Aktiengesellschaft Pyrrolopyrimidines for pharmaceutical compositions
TW200900065A (en) 2007-03-07 2009-01-01 Janssen Pharmaceutica Nv 3-cyano-4-(4-pyridinyloxy-phenyl)-pyridin-2-one derivatives
TW200845978A (en) 2007-03-07 2008-12-01 Janssen Pharmaceutica Nv 3-cyano-4-(4-tetrahydropyran-phenyl)-pyridin-2-one derivatives
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UY33241A (es) 2010-02-26 2011-09-30 Boehringer Ingelheim Int ?Tienopirimidinas que contienen heterocicloalquilo para composiciones farmacéuticas?.
WO2011104340A1 (en) 2010-02-26 2011-09-01 Boehringer Ingelheim International Gmbh Thienopyrimidines containing a substituted alkyl group for pharmaceutical compositions
TW201219401A (en) 2010-09-14 2012-05-16 Lexicon Pharmaceuticals Inc Bicyclic inhibitors of Notum Pectinacetylesterase and methods of their use
JP5852665B2 (ja) 2010-11-08 2016-02-03 ジヤンセン・フアーマシユーチカルズ・インコーポレーテツド １，２，４−トリアゾロ［４，３−ａ］ピリジン誘導体およびｍＧｌｕＲ２受容体のポジティブアロステリックモジュレーターとしてのそれらの使用
WO2012062759A1 (en) 2010-11-08 2012-05-18 Janssen Pharmaceuticals, Inc. 1,2,4-TRIAZOLO[4,3-a]PYRIDINE DERIVATIVES AND THEIR USE AS POSITIVE ALLOSTERIC MODULATORS OF MGLUR2 RECEPTORS
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AR090037A1 (es) 2011-11-15 2014-10-15 Xention Ltd Derivados de tieno y/o furo-pirimidinas y piridinas inhibidores de los canales de potasio
JPWO2014073627A1 (ja) * 2012-11-09 2016-09-08 住友化学株式会社 植物の生長を促進する方法
JO3368B1 (ar) 2013-06-04 2019-03-13 Janssen Pharmaceutica Nv مركبات 6، 7- ثاني هيدرو بيرازولو [5،1-a] بيرازين- 4 (5 يد)- اون واستخدامها بصفة منظمات تفارغية سلبية لمستقبلات ميجلور 2
JO3367B1 (ar) 2013-09-06 2019-03-13 Janssen Pharmaceutica Nv مركبات 2،1، 4- ثلاثي زولو [3،4-a] بيريدين واستخدامها بصفة منظمات تفارغية موجبة لمستقبلات ميجلور 2
FR3015483B1 (fr) * 2013-12-23 2016-01-01 Servier Lab Nouveaux derives de thienopyrimidine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
AU2015208233B2 (en) 2014-01-21 2019-08-29 Janssen Pharmaceutica Nv Combinations comprising positive allosteric modulators or orthosteric agonists of metabotropic glutamatergic receptor subtype 2 and their use
ES2860298T3 (es) 2014-01-21 2021-10-04 Janssen Pharmaceutica Nv Combinaciones que comprenden moduladores alostéricos positivos del receptor glutamatérgico metabotrópico de subtipo 2 y su uso
KR20180075228A (ko) * 2016-12-26 2018-07-04 한미약품 주식회사 싸이에노피리미딘 화합물의 신규 제조방법 및 중간체
RU2746282C1 (ru) * 2020-07-30 2021-04-12 Федеральное государственное бюджетное образовательное учреждение высшего образования "Кубанский государственный университет" (ФГБОУ ВО "КубГУ") Способ повышения урожайности озимой пшеницы

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GB1570494A (en) * 1975-11-28 1980-07-02 Ici Ltd Thienopyrimidine derivatives and their use as pesticides
ZA782648B (en) * 1977-05-23 1979-06-27 Ici Australia Ltd The prevention,control or eradication of infestations of ixodid ticks

Also Published As

Publication number Publication date
EP0447891A1 (de) 1991-09-25
DE59101477D1 (de) 1994-06-01
DE4008726A1 (de) 1991-09-26
EP0447891B1 (de) 1994-04-27
DK0447891T3 (da) 1994-05-30
CA2038521A1 (en) 1991-09-20
JPH04217685A (ja) 1992-08-07

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