ES2044968T3 - Complejo de amida. - Google Patents
Complejo de amida.Info
- Publication number
- ES2044968T3 ES2044968T3 ES87730111T ES87730111T ES2044968T3 ES 2044968 T3 ES2044968 T3 ES 2044968T3 ES 87730111 T ES87730111 T ES 87730111T ES 87730111 T ES87730111 T ES 87730111T ES 2044968 T3 ES2044968 T3 ES 2044968T3
- Authority
- ES
- Spain
- Prior art keywords
- saturated
- carbamyl
- groups
- rest
- atoms
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
- C07D295/182—Radicals derived from carboxylic acids
- C07D295/185—Radicals derived from carboxylic acids from aliphatic carboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/0474—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group
- A61K51/0478—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group complexes from non-cyclic ligands, e.g. EDTA, MAG3
- A61K51/048—DTPA (diethylenetriamine tetraacetic acid)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
- C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
- C07C237/04—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
- C07C237/08—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated having the nitrogen atom of at least one of the carboxamide groups bound to an acyclic carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
- C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
- C07C237/22—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton having nitrogen atoms of amino groups bound to the carbon skeleton of the acid part, further acylated
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/20—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms
- C07D211/22—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
- C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
- C07D265/30—1,4-Oxazines; Hydrogenated 1,4-oxazines not condensed with other rings
- C07D265/32—1,4-Oxazines; Hydrogenated 1,4-oxazines not condensed with other rings with oxygen atoms directly attached to ring carbon atoms
- C07D265/33—Two oxygen atoms, in positions 3 and 5
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2123/00—Preparations for testing in vivo
Abstract
UNIONES DE LA FORMULA GENERAL, QUEDANDO N LOS NUMEROS 0, 1 O 2 R1 Y R2 ATOMOS DE HIDROGENO, GRUPOS DE AICINITA, GRUPOS DE FENILO, GRUPOS DE BENCILO O CUANDO N ESTA POR EL NUMERO 0 A LA VEZ POR UN GRUPO DE TRIMETILENO O TETRAMETILENO. R3 UN RESTO DE HIDROCARBURO CICLICO ALIPATICO, SATURADO O NO SATURADO ENCADENADO DIRECTAMENTE O DIVIDIDO, CON HASTA 16 ATOMOS C, O CUADO R4 ES UN ATOMO DE HIDROGENO, UN CICLOALQUILO O UN GRUPO ARAQUILOS SUSTITUIDO POR UNO O VARIOS GRUPOS DE ALQUILAMINO DI-C1-C6 O UNO O VARIOS GRUPOS DE ALCOXIDOS C1-C6. RN UN ATOMO DE HIDROGENO SATURADO O NO SATURADO, ENCADENAMIENTO DIRECTO O DOBLE O RESTO DE HIDROCARBURO CICLICO DE HASTA 16 ATOMOS. R3 Y R4 EN UNION SATURADO O NO SATURADO Y EN SU CASO CON UNO O VARIOS C1-C6 ALQUILAMICO C2-C6 ACILO, HIDROXICARBAMILO, CARBAMILO SUSTITUIDO C1-C6 ACILO EN CARBAMILO-NITROGENO UNO O DOS RETOS C1-C6 ACILO, QUE FORMAN UN ANILLO EN ATOMOS DE OXIGENO. CARBAMILO O UN C1-C6 ACILAMINO O C1-C6 RESTO DE ALQUILAMO SUSTITUIDOS EN ANILLO DE 5 O6 QUE A SU VEZ CONTIENE UN GRUPO DE CARBAMILO O UN ATOMO DE NITROGENO, OXIGENO O SULFURO. X UN ATOMO DE HIDROGENO Y/O UN EQUIVALENTE DE ION METALICO. Y UN GRUPO COSC SIGNIFICA: ASI COMO SUS SALES CON BASES ORGANICAS O INORGANICAS SON IMPORTENTES FORMACIONES DE COMPLEJOS Y COMPLEJOS DE SALES.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19863633245 DE3633245A1 (de) | 1986-09-26 | 1986-09-26 | Cyclische amid-komplexe |
DE19863633246 DE3633246A1 (de) | 1986-09-26 | 1986-09-26 | Amid-komplexe |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2044968T3 true ES2044968T3 (es) | 1994-01-16 |
Family
ID=25847991
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES87730111T Expired - Lifetime ES2044968T3 (es) | 1986-09-26 | 1987-09-23 | Complejo de amida. |
Country Status (13)
Country | Link |
---|---|
US (1) | US5693310A (es) |
EP (1) | EP0263059B1 (es) |
JP (1) | JP2509247B2 (es) |
AU (1) | AU612119B2 (es) |
DE (1) | DE3782606D1 (es) |
DK (1) | DK174771B1 (es) |
ES (1) | ES2044968T3 (es) |
GR (1) | GR3006370T3 (es) |
IE (1) | IE62181B1 (es) |
IL (1) | IL83966A (es) |
NO (1) | NO175364C (es) |
NZ (1) | NZ221932A (es) |
PT (1) | PT85794B (es) |
Families Citing this family (109)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3640708C2 (de) * | 1986-11-28 | 1995-05-18 | Schering Ag | Verbesserte metallhaltige Pharmazeutika |
GB9007965D0 (en) * | 1990-04-09 | 1990-06-06 | Nycomed As | Compounds |
US5399340A (en) * | 1987-09-24 | 1995-03-21 | Schering Aktiengesellschaft | Use of amide complex compounds |
DE3927444A1 (de) * | 1989-08-16 | 1991-02-28 | Schering Ag | Verwendung von amid-komplexverbindungen |
AU641361B2 (en) * | 1988-05-02 | 1993-09-23 | Zynaxis Technologies, Incorporated | Compounds, compositions and method for binding bio-affecting substances to surface membranes of bio-particles |
US5094950A (en) * | 1988-06-07 | 1992-03-10 | Nihon Medi-Physics Co., Ltd. | Diethylenetriamine pentaacetic acid derivatives |
US5137711A (en) * | 1988-07-19 | 1992-08-11 | Mallickrodt Medical, Inc. | Paramagnetic dtpa and edta alkoxyalkylamide complexes as mri agents |
US5130120A (en) * | 1988-07-19 | 1992-07-14 | Mallinckrodt Medical, Inc. | Paramagnetic DTPA and EDTA alkoxyalkylamide complexes as MRI agents |
NZ230778A (en) * | 1988-09-27 | 1993-01-27 | Salutar Inc | Diagnostic imaging contrast medium comprising biscarbamoyl derivatives |
US5314681A (en) * | 1988-12-23 | 1994-05-24 | Nycomed Innovation Ab | Composition of positive and negative contrast agents for electron spin resonance enhanced magnetic resonance imaging |
GB8900719D0 (en) * | 1989-01-13 | 1989-03-08 | Nycomed As | Compounds |
US5011925A (en) * | 1989-03-09 | 1991-04-30 | Mallinckrodt, Inc. | Morpholinoamido EDTA derivatives |
US5384108A (en) * | 1989-04-24 | 1995-01-24 | Mallinckrodt Medical, Inc. | Magnetic resonance imaging agents |
US5695739A (en) * | 1989-06-30 | 1997-12-09 | Schering Aktiengesellschaft | Derivatized DTPA complexes, pharmaceutical agents containing these compounds, their use, and processes for their production |
DE3922005A1 (de) * | 1989-06-30 | 1991-01-10 | Schering Ag | Derivatisierte dtpa-komplexe, diese verbindungen enthaltende pharmazeutische mittel, ihre verwendung und verfahren zu deren herstellung |
US6039931A (en) * | 1989-06-30 | 2000-03-21 | Schering Aktiengesellschaft | Derivatized DTPA complexes, pharmaceutical agents containing these compounds, their use, and processes for their production |
GB8916781D0 (en) * | 1989-07-21 | 1989-09-06 | Nycomed As | Compositions |
US5516503A (en) * | 1989-11-16 | 1996-05-14 | Guerbet S.A. | Diagnostic composition comprising a binuclear complex, its method of preparation and its use in magnetic resonance imaging |
FR2654344B1 (fr) * | 1989-11-16 | 1994-09-23 | Cis Bio Int | Complexe paramagnetique de gadolinium, son procede de preparation et son utilisation pour le diagnostic par irm. |
WO1992017215A1 (en) * | 1990-03-28 | 1992-10-15 | Nycomed Salutar, Inc. | Contrast media |
US5843399A (en) * | 1990-04-06 | 1998-12-01 | Schering Aktiengesellschaft | DTPA monoamides for MRI |
DE4011684A1 (de) | 1990-04-06 | 1991-10-10 | Schering Ag | Dtpa-monoamide, diese verbindungen enthaltende pharmazeutische mittel, ihre verwendung und verfahren zu deren herstellung |
GB9007967D0 (en) * | 1990-04-09 | 1990-06-06 | Nycomed As | Compounds |
JP2776953B2 (ja) * | 1990-04-10 | 1998-07-16 | 日本メジフィジックス株式会社 | 多官能性金属キレート化合物とその用途 |
US5077037A (en) * | 1990-08-03 | 1991-12-31 | Mallinckrodt Medical, Inc. | Novel compositions for magnetic resonance imaging |
IE920996A1 (en) * | 1991-03-27 | 1992-10-07 | Nycomed Salutar | Contrast media |
JP2807852B2 (ja) * | 1991-07-18 | 1998-10-08 | 株式会社ミドリ十字 | 新規キレート化剤、該キレート化剤と金属原子との錯化合物及びそれを含む診断剤 |
US6875864B2 (en) | 1991-08-01 | 2005-04-05 | Bracco International B.V. | Aminocarboxylate ligands having substituted aromatic amide moieties |
EP0702677A1 (en) * | 1994-04-08 | 1996-03-27 | BRACCO International B.V. | Aromatic amide compounds and metal chelates thereof |
US5672335A (en) * | 1994-11-30 | 1997-09-30 | Schering Aktiengesellschaft | Use of metal complexes as liver and gallbladder X-ray diagnostic agents |
DE19507820A1 (de) * | 1995-02-21 | 1996-08-22 | Schering Ag | Neuartig substituierte DTPA-Derivate, deren Metallkomplexe, diese Komplexe enthaltende pharmazeutische Mittel, deren Verwendung in der Diagnostik, sowie Verfahren zur Herstellung der Komplexe und Mittel |
DE19646762B4 (de) * | 1996-11-04 | 2004-05-13 | Schering Ag | Verwendung von Metallverbindungen zur Herstellung von Mitteln zur Strahlentherapie von Tumoren |
AR014975A1 (es) * | 1998-04-08 | 2001-04-11 | Nps Pharma Inc | Compuestos calciliticos, una composicion farmaceutica que los comprende, y el uso de los mismos para la fabricacion de un medicamento |
US6153655A (en) * | 1998-04-17 | 2000-11-28 | Enzon, Inc. | Terminally-branched polymeric linkers and polymeric conjugates containing the same |
US6455734B1 (en) | 2000-08-09 | 2002-09-24 | Magnesium Diagnostics, Inc. | Antagonists of the magnesium binding defect as therapeutic agents and methods for treatment of abnormal physiological states |
US6756037B2 (en) | 2000-03-31 | 2004-06-29 | Enzon, Inc. | Polymer conjugates of biologically active agents and extension moieties for facilitating conjugation of biologically active agents to polymeric terminal groups |
US6777387B2 (en) | 2000-03-31 | 2004-08-17 | Enzon Pharmaceuticals, Inc. | Terminally-branched polymeric linkers containing extension moieties and polymeric conjugates containing the same |
CA2419811A1 (en) | 2000-08-18 | 2002-02-28 | Atritech, Inc. | Expandable implant devices for filtering blood flow from atrial appendages |
MXPA03007392A (es) * | 2001-02-20 | 2003-12-04 | Enzon Inc | Enlazantes polimericos ramificados terminalmente y conjugados polimericos que contienen los mismos. |
US8603160B2 (en) | 2003-12-23 | 2013-12-10 | Sadra Medical, Inc. | Method of using a retrievable heart valve anchor with a sheath |
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EP2529697B1 (en) | 2003-12-23 | 2014-01-29 | Sadra Medical, Inc. | Repositionable heart valve |
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US20050137694A1 (en) | 2003-12-23 | 2005-06-23 | Haug Ulrich R. | Methods and apparatus for endovascularly replacing a patient's heart valve |
US9005273B2 (en) | 2003-12-23 | 2015-04-14 | Sadra Medical, Inc. | Assessing the location and performance of replacement heart valves |
US7329279B2 (en) | 2003-12-23 | 2008-02-12 | Sadra Medical, Inc. | Methods and apparatus for endovascularly replacing a patient's heart valve |
US20050137687A1 (en) | 2003-12-23 | 2005-06-23 | Sadra Medical | Heart valve anchor and method |
US7381219B2 (en) | 2003-12-23 | 2008-06-03 | Sadra Medical, Inc. | Low profile heart valve and delivery system |
US7988724B2 (en) | 2003-12-23 | 2011-08-02 | Sadra Medical, Inc. | Systems and methods for delivering a medical implant |
US7959666B2 (en) | 2003-12-23 | 2011-06-14 | Sadra Medical, Inc. | Methods and apparatus for endovascularly replacing a heart valve |
US8840663B2 (en) | 2003-12-23 | 2014-09-23 | Sadra Medical, Inc. | Repositionable heart valve method |
US7780725B2 (en) | 2004-06-16 | 2010-08-24 | Sadra Medical, Inc. | Everting heart valve |
US11278398B2 (en) | 2003-12-23 | 2022-03-22 | Boston Scientific Scimed, Inc. | Methods and apparatus for endovascular heart valve replacement comprising tissue grasping elements |
US9526609B2 (en) | 2003-12-23 | 2016-12-27 | Boston Scientific Scimed, Inc. | Methods and apparatus for endovascularly replacing a patient's heart valve |
US7445631B2 (en) | 2003-12-23 | 2008-11-04 | Sadra Medical, Inc. | Methods and apparatus for endovascularly replacing a patient's heart valve |
US8343213B2 (en) | 2003-12-23 | 2013-01-01 | Sadra Medical, Inc. | Leaflet engagement elements and methods for use thereof |
US8579962B2 (en) | 2003-12-23 | 2013-11-12 | Sadra Medical, Inc. | Methods and apparatus for performing valvuloplasty |
DE102005003632A1 (de) | 2005-01-20 | 2006-08-17 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Katheter für die transvaskuläre Implantation von Herzklappenprothesen |
US7962208B2 (en) | 2005-04-25 | 2011-06-14 | Cardiac Pacemakers, Inc. | Method and apparatus for pacing during revascularization |
US20070213813A1 (en) | 2005-12-22 | 2007-09-13 | Symetis Sa | Stent-valves for valve replacement and associated methods and systems for surgery |
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US7896915B2 (en) | 2007-04-13 | 2011-03-01 | Jenavalve Technology, Inc. | Medical device for treating a heart valve insufficiency |
ES2903231T3 (es) | 2008-02-26 | 2022-03-31 | Jenavalve Tech Inc | Stent para el posicionamiento y anclaje de una prótesis valvular en un sitio de implantación en el corazón de un paciente |
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CN102245256B (zh) | 2008-10-10 | 2014-07-23 | 萨德拉医学公司 | 医疗装置以及用于输送医疗装置的输送系统 |
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ES2890650T3 (es) * | 2012-11-26 | 2022-01-21 | Univ North Carolina Chapel Hill | Esteres de di-etilo de DTPA, composiciones de los mismos, y métodos para utilizar los mismos |
EP3038567B1 (en) | 2013-08-30 | 2022-09-07 | JenaValve Technology, Inc. | Radially collapsible frame for a prosthetic valve and method for manufacturing such a frame |
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US10449043B2 (en) | 2015-01-16 | 2019-10-22 | Boston Scientific Scimed, Inc. | Displacement based lock and release mechanism |
US9861477B2 (en) | 2015-01-26 | 2018-01-09 | Boston Scientific Scimed Inc. | Prosthetic heart valve square leaflet-leaflet stitch |
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US10426617B2 (en) | 2015-03-06 | 2019-10-01 | Boston Scientific Scimed, Inc. | Low profile valve locking mechanism and commissure assembly |
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EP3632378A1 (en) | 2015-05-01 | 2020-04-08 | JenaValve Technology, Inc. | Device and method with reduced pacemaker rate in heart valve replacement |
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US10179041B2 (en) | 2015-08-12 | 2019-01-15 | Boston Scientific Scimed Icn. | Pinless release mechanism |
WO2017089847A1 (en) | 2015-11-26 | 2017-06-01 | Debreceni Egyetem | New 3,6,9, 15-tetraaza-bicyclo [9.3.1 ]pentadeca- 1(14), 11(15), 12-triene based compounds and their application as ligands of essential metal ion based mri and 52mn based pet contrast agents |
WO2017089848A1 (en) | 2015-11-26 | 2017-06-01 | Debreceni Egyetem | New 2, 1 l -diaza-[3.3](2,6)pyridinophane compounds and their application as ligands of essential metal ion based mri contrast agents and 52mn based pet contrast agents |
US10494379B2 (en) | 2015-11-26 | 2019-12-03 | Debreceni Egyetem | 6-oxa-3,9,15-triaza-bicyclo[9.3.1]pentadeca-1(14),11(15),12-triene derivatives based compounds and their application as ligands of essential metal ion based MRI and 52MN based PET contrast agents |
US10342660B2 (en) | 2016-02-02 | 2019-07-09 | Boston Scientific Inc. | Tensioned sheathing aids |
US10583005B2 (en) | 2016-05-13 | 2020-03-10 | Boston Scientific Scimed, Inc. | Medical device handle |
EP3454795B1 (en) | 2016-05-13 | 2023-01-11 | JenaValve Technology, Inc. | Heart valve prosthesis delivery system for delivery of heart valve prosthesis with introducer sheath and loading system |
US10201416B2 (en) | 2016-05-16 | 2019-02-12 | Boston Scientific Scimed, Inc. | Replacement heart valve implant with invertible leaflets |
EP3573579B1 (en) | 2017-01-27 | 2023-12-20 | JenaValve Technology, Inc. | Heart valve mimicry |
US10828154B2 (en) | 2017-06-08 | 2020-11-10 | Boston Scientific Scimed, Inc. | Heart valve implant commissure support structure |
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-
1987
- 1987-09-21 IL IL83966A patent/IL83966A/xx unknown
- 1987-09-22 JP JP62236402A patent/JP2509247B2/ja not_active Expired - Lifetime
- 1987-09-23 DK DK198705003A patent/DK174771B1/da not_active IP Right Cessation
- 1987-09-23 EP EP87730111A patent/EP0263059B1/de not_active Expired - Lifetime
- 1987-09-23 DE DE8787730111T patent/DE3782606D1/de not_active Expired - Lifetime
- 1987-09-23 ES ES87730111T patent/ES2044968T3/es not_active Expired - Lifetime
- 1987-09-25 NZ NZ221932A patent/NZ221932A/xx unknown
- 1987-09-25 IE IE257987A patent/IE62181B1/en not_active IP Right Cessation
- 1987-09-25 AU AU78995/87A patent/AU612119B2/en not_active Ceased
- 1987-09-25 PT PT85794A patent/PT85794B/pt unknown
- 1987-09-25 NO NO874031A patent/NO175364C/no unknown
-
1990
- 1990-11-19 US US07/614,947 patent/US5693310A/en not_active Expired - Lifetime
-
1992
- 1992-11-26 GR GR920402741T patent/GR3006370T3/el unknown
Also Published As
Publication number | Publication date |
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IE872579L (en) | 1988-03-26 |
DK500387A (da) | 1988-03-27 |
IL83966A0 (en) | 1988-02-29 |
IE62181B1 (en) | 1994-12-28 |
NO874031D0 (no) | 1987-09-25 |
AU7899587A (en) | 1988-03-31 |
EP0263059B1 (de) | 1992-11-11 |
DE3782606D1 (de) | 1992-12-17 |
NO175364C (no) | 1994-10-05 |
EP0263059A3 (en) | 1989-02-22 |
NO874031L (no) | 1988-03-28 |
DK500387D0 (da) | 1987-09-23 |
NZ221932A (en) | 1990-07-26 |
EP0263059A2 (de) | 1988-04-06 |
IL83966A (en) | 1992-03-29 |
PT85794B (pt) | 1990-08-31 |
JPS6393758A (ja) | 1988-04-25 |
US5693310A (en) | 1997-12-02 |
DK174771B1 (da) | 2003-10-27 |
NO175364B (no) | 1994-06-27 |
GR3006370T3 (es) | 1993-06-21 |
AU612119B2 (en) | 1991-07-04 |
PT85794A (de) | 1987-10-01 |
JP2509247B2 (ja) | 1996-06-19 |
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